Amino Acids (AA)

<p>Applications 5,6-Dihydro-5-methyluridine (cas# 23067-10-9) is a useful research chemical.<br></p>

<p>Applications A reagent used to synthesize 5-HT2A and 5-HT3 receptor ligands for use in treating CNS-related disorders.<br>References Bermudez, J., et al.: J. Med. Chem., 33, 1924 (1990),<br></p>

<p>Applications 9-(N-Methylaminomethyl)anthracene is a reactant that has been used in the synthesis of anthracene-oxyquinoline dyad as a fluorescent indicator for Hg(II).<br>References Praveen, L., et. al.: Tetrahedron Lett., 53, 3951 (2012)<br></p>

<p>Applications L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.<br>References Demant, T. et al.: Am. J. Physiol., 270, E1022 (1996); Diraison, F. et al.: Am. J. Physiol., 277, E529 (1999); Suryawan, A. et al.: J. Anim. Sci., 89, 2004 (2011); Peyrollier, K. et al.: Biochem. J., 350, 361 (2000);<br></p>

<p>Applications 5-Methylfurfural is a common chemical reagent used in a wide variety of chemical reactions and organic synthesis. Polycyclic pyridazine based derivatives are synthesized with this compound to form antimicrobial agents. Also used in the preparation of antiinflammatory diarylpentanoid analogues.<br>References Deeb, A. et al.: Eur. Chem. Bull., 3, 897 (2014); Leong, S. et al.: Molecules, 19, 16058 (2014);<br></p>

<p>Stability Very Hygroscopic<br>Applications Hydroxyisovaleroyl Carnitine is used as a diagnostic tool to identify the presence of orofacial clefts. Also used in the screening and diagnostics of inborn errors of metabolism.<br>References Denes, J. et al.: Anal. Chem., 84, 10113 (2012); Budner, M. et al.: Arch. Oral. Biol., 58, 459 (2013);<br></p>

<p>Applications L-Serine (15n, 98%) (cas# 59935-32-9) is a useful research chemical.<br></p>

<p>Applications 3,4-Dihydroxy-5-methoxybenzoic acid (cas# 3934-84-7) is a useful research chemical.<br></p>

<p>Applications L-2-Aminobutyric Acid-d6 is the isotope labelled analog of L-2-Aminobutyric Acid (A602930); a receptor antagonist.<br>References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995)<br></p>

<p>Applications Fmoc-Ser(TBDMS)-OH (cas# 146346-81-8) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications N-Isopropyl-N-methylamine (cas# 4747-21-1) is a compound useful in organic synthesis.<br> E0<br></p>

<p>Applications Methylpropylnitrosamine is used in biological studies as human liver microsomal cytochrome P-450 enzymes which are involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.<br>References Shimada, T., et al.: Cancer Res., 48, 3218 (1989);<br></p>

<p>Applications 12-(t-Boc-amino)-1-dodecanol (cas# 67341-03-1) is a compound useful in organic synthesis.<br></p>

<p>Impurity Ranitidine EP Impurity H<br>Applications N-Methylnitroacetamide (Ranitidine EP Impurity H) is a degradation product of Ranitidine (R120000).<br>References Sharma, N. et al.: Sci. Pharmac., 79, 309 (2011); Haywood, P.A. et al.: J. Chem. Soc., 5, 951 (1987);<br></p>

<p>Applications Ac-lys(ac)-oh was used in the reaction of HOCl with amino acids and peptides with ESR evidence for rapid rearrangement and fragmentation reactions of nitrogen-centered radicals.<br>References Hawkins, C., et al.: J. Chem. Soc. Perkin Trans. 2, 9, 1937 (1998);<br></p>

<p>Applications: Isotope labelled analogue of 2-Methoxyacetic Acid, a synthetic intermediate in the synthesis of dimethyl(alkyloxy)[(methylsulfonyl)phenyl]furanones as COX-2 inhibitors.<br>Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leblanc, Y., et al.: Bioorg. Med. Chem. Lett., 9, 2207 (1999);<br></p>

<p>Stability Hygroscopic<br>Applications Chlorobutanol is used as a preservative and sedative. It has also been shown to exhibit antibacterial properties.<br>References Dutta, T., et al.: PCT Int. Appl., 22, (2020); Ibibia, E., et al.: Asian. J. Pharm. Clin. Res., 9, 179-182 (2016)<br></p>

<p>Applications 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole, is a 4-methyl-1H-imidazole (4-MEI) derivative.<br></p>

<p>Applications A product from thermal and hydrolytic degradation of Orlistat. Orlistat impurity.<br>References Stalder, H., et al.: Helv. Chimica Acta, 75, 1593 (1992),<br></p>

<p>Applications A nitroamino subsituted primary alcohol.<br></p>

<p>Applications 2-ethyl-6-methylpyrazine (cas# 13925-03-6) is a useful research chemical.<br></p>

<p>Applications 5-Amino-6-methylbenzimidazolone<br></p>

<p>Applications 1-Boc-4-(6-aminopyridin-3-yl)piperazine is used to prepare pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of cyclin-dependent kinases 4 and 6.<br>References Toogood, P., et al.: J. Med. Chem., 48, 2388 (2005); Cho, Y., et al.: J. Med. Chem., 53, 7938 (2010)<br></p>

<p>Applications (2-methylphenoxy)acetic acid (cas# 1878-49-5) is a useful research chemical.<br></p>

<p>Impurity Cyclobenzaprine USP Related Compound A<br>Applications 5-Hydroxy-N-methylprotriptyline acts as a reducing agent in chemical reactions. Cyclobenzaprine USP Related Compound A.<br>References Gribble, G. et al.: Synthesis., 3, 172 (1977);<br></p>

<p>Stability Air Sensitive<br>Applications N-Methyl-L-cysteine Hydrochloride is an intermediate used to prepare analogs of pyochelin (P840365), a siderophore of Pseudomonas aeruginosa.<br>References Rivault, F., et al.: Tetrahedron, 60, 12139 (2004); Noel, S., et al.: Bioorgan. Chem. Lett., 24, 132 (2014); Ankenbauer, R., et al.: J. Bacteriol., 170, 5344 (1988)<br></p>

<p>Applications 4-Methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-amine can be used as reactant/reagent in preparation of N-phenylsulfony-N'-pyrimidinylureas as herbicides.<br>References Hamprecht, G., et al.: Ger. Offen., DE 4322726 A1 19950112 (1995)<br></p>

<p>Applications Labelled L-Methionine, an essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.<br>References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),<br></p>

<p>Applications An inhibitor of the enzyme Glyoxalase 1.<br>References Vince, R. and Wadd, W.B.: Biochemical and Biophysical Res. Commun., 35, 5 (1969), Vegvari, A., et al.: ChemBioChem, 3(11), 1117 (2002)<br></p>

<p>Applications 6-Methylquinoline, is a building block used for the synthesis of various pharmaceutical compounds, and biologically active compounds. It can be used for the preparation of pyranobenzopyrone compounds, having anti-norovirus activity.<br>References Pokhrel, L., et al.: bioorg. Med. Chem. Lett., 22, 3480 (2012);<br></p>

<p>Applications Zinc Glycinate is used in the preparation of hydroxy acid complexes used in skin antiaging, acne and skin whitening formulations.<br></p>

<p>Applications Calcium D-gluconate monohydrate (cas# 66905-23-5) is a useful research chemical.<br></p>

<p>Stability Temperature Sensitive, Light Sensitive<br>Applications 2-Ethyl-4-methylpentyl Acrylate<br></p>

<p>Stability Air Sensitive<br>Applications 4-Chloro-2-methylaniline<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications 3-Methyl-2-oxobutyric acid calcium salt (cas# 51828-94-5) is a useful research chemical.<br></p>

<p>Applications 1-(4-Hydroxy-3-methoxyphenyl)-1-propanone is a derivative of Guaiacol, a precursor to various flavorants, such as eugenol and vanillin.<br>References Allen, C., et al.: Org. Synth., 3, 418 (1955); Esposito, L., et al.: Kirk-Othmer Encyclopedia of Chemical Technology, 4th edition, 24, 812 (1997)<br></p>

<p>Applications D-Homotyrosine hydrobromide<br></p>

<p>Applications N-Benzyloxycarbonyl L-Threonine Amide O-Methanesulfonate (cas# 80082-51-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methoxy-3-methylaniline is an important building block.<br></p>

<p>Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.<br>References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)<br></p>

<p>Applications A receptor adenine derivative binding membrane brain animal cell line.<br>References Camaioni, E., et al.: Bioorg. Med. Chem., 6, 523 (1998), Kelly, M., et al.: Br. J. Pharmacol., 125, 979 (1998), Redzic, Z., et al.: Brain Res., 888, 66 (2001), Levy, D., et al.: J. Med. Chem., 46, 2177 (2003),<br></p>

<p>M03060 - H-Leu-OH</p>

<p>Applications 5-Methyl-5-phenylhydantoin is a reactant for synthesis of beta-amino alcohols as inhibitors of anti-tubercular target N-acetyltransferase, chlorohydantoins and specific MMP inhibitors.<br>References Fullam, E., et al.: Bioorg. Med. Chem. Lett., 21, 1185 (2011); Whitehead, D., et al.: Tetrahedron Lett., 50, 3 (2009); Chollet, A., et al.: Bioorg. Med. Chem., 10, 531 (2002)<br></p>

<p>Applications 2-Azido-2-deoxy-D-glucose is a glucose derivative that have been used to study the substrate specificity of galactokinase.<br>References Zou, W., et al.: Bioorg. Med. Chem. Lett., 22, 3540 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Methyl-2-benzothiazolinone Hydrazone Hydrochloride Hydrate is a chromegenic reagent for the determination of benzodiazepines, cholesterol, and enzyme activity. 3-Methyl-2-benzothiazolinone Hydrazone Hydrochloride Hydrate is used as an electrophilic coupling reagent used in the spectrophotometric determination of chloramine-B (CAB) and other residual chlorine content in various environmental water samples.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Syed, A. et al.: Environ. Sci. Indian J., 3, 49 (2008); Syed, A.A. et al.: Chem. Environ. Res., 15, 41 (2006); Mohan, J. et al.: Indian J. Chem., 32B, 44 (1993);<br></p>

<p>Applications L-Threonic acid calcium salt is the salt of L-Threonic acid, a naturally occurring compound that can be found in the leaves of Pelargonium crispum. L-Threonic acid is also the degradation product of Dehydroascorbate (DHA), a metabolite of Vitamin C (A786990).<br>References Helsper, J. &amp; Loewus, F.: Plant Phys., 69, 1365 (1982); Koch, C. &amp; Biaglow, J.: J. Cell. Phys., 94, 299 (1978); Nielsen J., et al.: J. Agr. Food Chem., 49, 2998 (2001)<br></p>

<p>Stability Light Sensitive, Volatile<br>Applications Labelled 2-Methylfuran (M305440). 2-Methylfuran is a volatile organic compound (VOCs) used as a potential non-intrusive tool for screening of lung cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McWilliams, et al.: Curr. Oncol. Rep., 4, 487 (2002), Buszewski, B., et al.: Biomed. Chromatogr., 21, 553 (2007), Ligor, T., et al.: J. Breath. Res., 1, 1 (2007),<br></p>

<p>Applications 2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(3-(3-(tert-butyl)-4-hydroxy-5-methylphenyl)propanoate) (cas# 90498-90-1) is a useful compound used as a modifier for the thermo-oxidative stabilization of synthesized meterials such as polypropylene-based materials, and spider silk.<br>References Matta, A.; et al.: Polym. Degrad. Stab., 142, 50 (2017); Dao, A. T.; et al.: Polym. Degrad. Stab., 153, 37 (2018).<br></p>

<p>Applications 2-Methyl-5-nitrophenol is used as a reactant in the preparation of pyranocarbazole alkaloids.<br>References Zang, Yingda, et al.: Euro. J. of Med. Chem., 143, 438-448 (2018)<br></p>

<p>Applications Ethametsulfuron-methyl is a regulator of the early steps of complement activation on mucosal surfaces. It can be used in combination treatment of ohmic heating with various essential oil components for inactivation of food-​borne pathogens in buffered peptone water and salsa.<br>References Kim, S. S., et al.: Food Control, 80, 29 (2017); Reichhardt, M. P., et al.: Front Immunol, 7, 85 (2016)<br></p>

<p>Applications N-Acetylglycine-d5 is an isotopic analog of N-Acetyl-glycine (A178260), a derivative of Glycine (G615990). It is an intermediate used to synthesize rac 3-O-Methyl DOPA (M303805) which is an impurity of Levodopa.<br>References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001), Perera, A., et al.: J. Labelled Comp. Radiopharm., 46, 389 (2003),<br></p>

<p>Applications N-Acetyl-S-(2,5-dimethylbenzene)-L-cysteine-d3 (cas# 1331909-07-9) is a compound useful in organic synthesis.<br>References Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>