Amino Acids (AA)

<p>Applications 4-Chloro-2-methoxyphenol is used as a reagent in the synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists which may be used in development of treatment against autoimmue diseases and viral infections. Also used in the synthesis of novel inhibtors of P. falciparum enoyl-ACP-reductase which may be used in treatment of malaria.<br>References Guerrero, M., et al.: Bioorg. Med. Chem. Lett., 22, 537 (2012); Belluti, F., et al.: J. Med. Chem., 56, 7516 (2013);<br></p>

<p>Applications N-(Carboxymethyl)-N-[2-[(carboxymethyl)amino]ethyl]-glycine Calcium Salt Hydrate is an intermediate used to prepare copper alkylenediaminetriacetic acid complexes.<br>References Matovic, Z., et al.: Inorganica Chimica Acta, 360, 2420 (2007)<br></p>

<p>Applications 2-Methylindoline is an intermediate in the production of various indole derivatives<br>References Severino, B., et al.: Bioorg. Med. Chem., 16, 6009 (2008); Zlotos, D., et al.: J. Med. Chem., 52, 826 (2009);<br></p>

<p>Applications Substrate for TenA enzyme in the thiamin salvage pathway<br>References Jenkins, A., et al.: Nat. Chem. Biol., 3, 492 (2007), Jenkins, A., et al.: Bioorg. Chem., 36, 29 (2008),<br></p>

<p>Applications 3-Methyl-1,3-butanediol is a useful compound in carbon oxygen coupling reactions.<br></p>

<p>Applications The selenocyanation and thiocyanation of electron rich arene, 1-Methylindole, achieved using N-iodosuccinimide (NIS) as a catalyst and aqueous tert-Bu hydroperoxide (TBHP) as an oxidant at room temperature.<br>References Muniraj, N., et al.: ChemistrySelect, 1, 1033-1038 (2016)<br></p>

<p>Stability Hygroscopic<br>Applications Hexanoyl-L-carnitine-(N-methyl-d3) Chloride, is the labeled analogue of Hexanoyl-L-carnitine Hydrochloride (H294440), which is used as reactant in the synthesis of carnitine benzyl esters as prodrugs.<br>References Gong, X., et. al.: J. Chem. Res., 6, 327 (2008)<br></p>

<p>Applications Threonine derivative used in the synthesis of peptide.<br>References Dekker, C.A., et al.: J. Biol. Chem., 180, 155 (1949),<br></p>

<p>Applications 2-Methoxy-1-[4-(oxiranylmethoxy)phenyl]ethanone (cas# 110458-44-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,6-Di-(tert-butyl-d9)-4-methylphenol-3,5-d2,OD (CAS# 64502-99-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methoxyphenol-3,4,5,6-d4 (CAS# 7329-52-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Piperazine derivative used as reference material for forensic laboratories.<br>References Brady, J., et al.: Drug Dev. Res., 20, 231 (1990), Winter, J., et al.: J. Pharmacol. Exp. Ther., 262, 682 (1992), Ator, N., et al.: Eur. J. Pharmacol., 241, 237 (1993), Forster, E., et al.: Eur. J. Pharmacol., 281, 81 (1995),<br></p>

<p>Stability Hygroscopic<br>Applications 2-Fluoro-4-methylphenylboronic Acid (cas# 170981-26-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Methylpropylnitrosamine is used in biological studies as human liver microsomal cytochrome P-450 enzymes which are involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.<br>References Shimada, T., et al.: Cancer Res., 48, 3218 (1989);<br></p>

<p>Applications 1-Ethyl-1-methylcyclopentane, is one of the chemical components of Gas-Phase organic carbon emissions from motor vehicles. It is also a volatile component of frying oils.<br>References Gentner, D. R., et al.: Environ. Sci. Tech., 47, 11937 (2013); Prevot, A. Frying Food, 155 (1988);<br></p>

<p>Applications 5-Methoxy-N-methyl-N-(1-methylethyl)-α-oxo-1H-indole-3-acetamide is an intermediate used in the synthesis of 5-Methoxy-N-methyl-N-isopropyl Tryptamine (M271680), which is a psychedelic tryptamine related to N-methyl-N-isopropyltryptamine. 5-Methoxy MiPT potently inhibits the re-uptake of the monoamines serotonin and norepinephrine but does not affect dopamine re-uptake. 5-Methoxy MiPT has no effect on the release of monoamines from rat brain synaptosomes. This product is intended for forensic and research applications.<br>References Katagi, M., et al.: Jpn. J. Forensic Toxicol., 20, 303 (2002), Meatherall, R., et al.: J. Anal. Toxicol., 27, 313 (2003), Wilson, J., et al.: Forensic Sci. Int., 148, 31 (2005), Kamata, T., et al.: Drug Metab. Dispos., 34, 281 (2006),<br></p>

<p>Impurity Ranitidine EP Impurity H<br>Applications N-Methylnitroacetamide (Ranitidine EP Impurity H) is a degradation product of Ranitidine (R120000).<br>References Sharma, N. et al.: Sci. Pharmac., 79, 309 (2011); Haywood, P.A. et al.: J. Chem. Soc., 5, 951 (1987);<br></p>

<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>

<p>Applications N-Methylaniline is used as an additive in gasoline because of its antiknock properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Li-jun, et al.: Huaxue Shiji, 37(1), 53-55, 96 (2015); Qin, Li-xia, et al.: Guangzhou Huagong, 43(8), 138-139, 148 (2015);<br></p>

<p>Applications 5-amino-2-methyl-benzenesulfonamide (cas# 6973-09-7) is a useful research chemical.<br></p>

<p>Applications 3-Methylbutyl Acetate-d3 (CAS# 1219804-75-7) is a useful isotopically labeled research compound.<br></p>

<p>Stability Volatile<br>Applications 2-Chloro-2-Methylpentane (cas# 4325-48-8) is a useful research chemical.<br></p>

<p>Applications Used in the methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins. Also used in the studies on the separation and photometric determination of antiepileptics.<br>References Quednow, B., et al.: Pharmazie, 34, 724 (1979),<br></p>

<p>Applications 1-(2-METHOXYPHENETHYL)PIPERAZINE (cas# 6722-54-9) is a useful research chemical.<br></p>

<p>Applications An inhibitor of the enzyme Glyoxalase 1.<br>References Vince, R. and Wadd, W.B.: Biochemical and Biophysical Res. Commun., 35, 5 (1969), Vegvari, A., et al.: ChemBioChem, 3(11), 1117 (2002)<br></p>

<p>Applications 4-Chloro-3-methylaniline (cas# 7149-75-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4'-Methylenebis[2-chlorophenol] is used in the manufacture of fire-resistant polyester material and is used in the synthesis of photo-sensitive print plates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yu, S. et al.: Faming Zhuanli Shenqing (2009), CN 101597219 A 20091209.<br></p>

<p>Stability Moisture Sensitive<br>Applications (Z)-Metominostrobin (cas# 133408-51-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methylpropylamine is used in the synthesis of arylsulfonamide inhibitors that act upon afflictions of osteoarthritis. In addition, it is used in the synthesis of novel reservatrol amide derivatives that act as anti-tumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yao, Ri-Sheng. et al.: Eur. J. Med. Chem. Lett., 62, 222 (2013); Nuti, E. et al.: Eur. j. Med. Chem., 62, 379 (2013)<br></p>

<p>Applications N-Acetyl-S-(3-hydroxypropyl)-L-cysteine Dicyclohexylamine Salt (unlabelled) (CAS# 14369-42-7) is a useful research compound.<br></p>

<p>Applications N-Fmoc-L-tyrosine Benzyl Ester is used to synthesize truncated analogues of preptin-(1-16) as possible osteoblast proliferation stimulant. It is also an intermediate used to prepare phosphotyrosinyl phosphoramidite derivatives useful in the incorporation of multiple reporter groups on synthetic oligonucleotides.<br>References Kowalczyk, R., et al.: Bioorg. Med. Chem., 22, 3565 (2014); Misiura, K., et al.: Nucl. Acids Res., 18, 4345 (1990)<br></p>

<p>Applications 4,4-methylenebis(N,N-diethylaniline) (cas# 135-91-1) is a useful research chemical.<br></p>

<p>Applications 5-((2-Hydroxyethyl)amino)-2-methylphenol (cas# 55302-96-0) is a useful research chemical.<br></p>

<p>Applications Ac-lys(ac)-oh was used in the reaction of HOCl with amino acids and peptides with ESR evidence for rapid rearrangement and fragmentation reactions of nitrogen-centered radicals.<br>References Hawkins, C., et al.: J. Chem. Soc. Perkin Trans. 2, 9, 1937 (1998);<br></p>

<p>Applications Dl-valine<br></p>

<p>Applications This compound contains up to 25% of the two other regioisiomers.<br></p>

<p>Applications 2-Methyl-7-methylamino-8-nitro-quinoxaline (cas# 78411-55-9) is a compound useful in organic synthesis.<br></p>

<p>Stability Air Sensitive<br>Applications N-Methyl-L-cysteine Hydrochloride is an intermediate used to prepare analogs of pyochelin (P840365), a siderophore of Pseudomonas aeruginosa.<br>References Rivault, F., et al.: Tetrahedron, 60, 12139 (2004); Noel, S., et al.: Bioorgan. Chem. Lett., 24, 132 (2014); Ankenbauer, R., et al.: J. Bacteriol., 170, 5344 (1988)<br></p>

<p>Applications Potassium 2-hydroxy-4-methoxybenzoate (cas# 152312-71-5) is a useful research chemical.<br></p>

<p>Applications 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine, can beused in the synthesis of Dibenzo[c,f][1,2]thiazepine derivatives.<br>References Gilleron, P., et al.: Bioorg. Med. Chem. Lett., 17, 5465 (2007),<br></p>

<p>Applications Tetrahydro-5-methyl-2-furanol is an intermediate in synthesizing 2,3-Dihydro-2-methylfuran (D447355), which is a general reagent used in next generation of biofuels. Dihydrofuranyl derivative.<br>References Simmie, J. et al.: J. Phys Chem., 116, 4528 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Methyl-2-oxobutyric acid calcium salt (cas# 51828-94-5) is a useful research chemical.<br></p>

<p>Applications 2-(Diphenylmethoxy)-N-methylethylamine is used in the pereparation of H1 and H2 receptor antagonists containing Diphenhydramine (D486900) derivatives. Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine (D486900) is categorized as an antihistaminic; sedative, hypnotic.<br>References Wolf, C. et al.: Archiv. de Pharm., 329, 87 (1996); Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),<br></p>

<p>Stability Hygroscopic<br>Applications endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine Acetate is an impurity of Granisetron HCl (G780000), a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy<br>References Kilpatrick, G.J., et al.: Nature, 330, 746 (1987), Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997), Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996),<br></p>

<p>Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>

<p>Applications 5-Methylfurfural is a common chemical reagent used in a wide variety of chemical reactions and organic synthesis. Polycyclic pyridazine based derivatives are synthesized with this compound to form antimicrobial agents. Also used in the preparation of antiinflammatory diarylpentanoid analogues.<br>References Deeb, A. et al.: Eur. Chem. Bull., 3, 897 (2014); Leong, S. et al.: Molecules, 19, 16058 (2014);<br></p>

<p>Applications N-t-Boc-2-bromoethylamine (Technical grade, ~90%) (cas# 39684-80-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-[2-(4-Hydroxyphenyl)-4-methylpentan-2-yl]phenol could be a useful reagent for making visible-transparent aromatic polymers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agou, T., et al.: Macromolecules (Washington, DC, U. S.), 53, 2942 (2020)<br></p>

<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>

<p>Applications 2-Methyl-1-phenyl-1-propene can be used in analytical study of analysis and comparison of aroma compounds from traditional Tangshan sorghum liquor and samples of improved fermentation process by GC-​MS.<br>References Jiang, X., et al.: Shipin Gongye Keji, 37, 87 (2016)<br></p>

<p>Applications 4-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 4-Methylimidazole is a product which results from the interaction of reducing sugars with ammonia. 4-Methylimidazole showed convulsant activity in animals and is listed as a possible carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969): Cunha, S.C. et al.: J. Food Comp. Anal., 24, 609 (2011); Chan, P.C. et al.: Arch. Toxicol., 82, 55 (2008);<br></p>