Amino Acids (AA)

<p>Applications N-Boc-piperazine (cas# 57260-71-6) is a compound useful in organic synthesis.<br></p>

<p>Impurity Imatinib EP Impurity G<br>Applications 1-Methylpiperazine (Imatinib EP Impurity G) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug. It is a COVID19-related research product.<br>References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);<br></p>

<p>Stability Hygroscopic<br>Applications Trigonelline-d3 HCl is deuterium labelled Trigonelline HCl. Trigonelline HCl has utility in developing site-specific system that delivers drugs to the brain. It has also been suggested as a potential anti-Alzheimer disease agent.<br>References Bodor, N., et al.: J. Med. Chem 26, 313 (1983); Makowska, J., et al.: J. Chromatogr. B 968, 101 (2014)<br></p>

<p>Applications 4-Hydroxy-4-methyl-2-pentanone-d12 (CAS# 114253-85-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Chloro-2-methylphenol can be used in the preparation of dichlorotoluqinones.<br>References James, C., et al.: J. Org. Chem., 16, 328 (1951)<br></p>

<p>Applications 1,2-Dichloro-2-methylpropane (cas# 594-37-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.<br>References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)<br></p>

<p>Applications Labelled 2-Methylbutyrylglycine (M294340). 2-Methylbutyrylglycine is one of the acylglycines, an important class of metabolites that have been used in the diagnosis of several inborn errors of metabolism (IEM).<br>References Costa, C., et al.: J. Pharmaceut. Biomed. Anal., 21, 1215 (2000), Garcia-Villoria, J., et al.: Clin. Biochem., 42, 2 (2009), Scalbert, A., et al.: Metabolomics, 5, 435 (2009),<br></p>

<p>Applications 3-Chloromethyl-5-methylpyridine is an intermediate in the synthesis of Rupatadine (R701650).<br>References Merlos, M., et al.: Pharmacol. Exp. Therap., 280, 114 (1997), Bell, I., et al.: J. Med. Chem., 41, 2146 (1998),<br></p>

<p>Impurity Esomeprazol EP Impurity A/ Omeprazole EP Impurity A<br>Applications 5-Methoxy-2-mercaptobenzimidazole (Esomeprazol EP Impurity A) is used in the synthesis of COX-2 inhibitors<br>References Frechette, S., et al.: Bioorg. Med. Chem. Lett., 18, 1502 (2008), Zhang, R., et al.: Eur. J. Med. Chem., 44, 3771 (2009),<br></p>

<p>Stability Temperature Sensitive<br>Applications Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate (cas# 1190403-86-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Azido-2-(2-methoxyethoxy)ethane (cas# 215181-61-6) is a useful research chemical.<br></p>

<p>Applications Ademethionine-d3 1,4-Butanedisulfonate, is a labeled analogue of Ademethionine 1,4-Butanedisulfonate (A280355), used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.<br></p>

<p>Applications 4-Methyl-valerophenone is an intermediate used in the synthesis of a-Pyrrolidinoisohexanophenone (Hydrochloride) (P841230), which is a phenone derivative used for research purposes.<br>References Guo, Z.K., et al.: Marine Drugs, 16, 45/1 (2018)<br></p>

<p>Applications 3-Methyl Salicylic Acid is a toxic compound, it’s toxicity is similar to salicylic acid. Reagent used in manufacturing and preparation of dyes.<br>References Egorova, T. V., et al.: Tekstil'naya Promyshlennost , 3, 48 (1987); Keshavarz, M. H., et al.: J. Hazard. Mater., 237, 79 (2012)<br></p>

<p>Applications (R)-D-Methioninol<br></p>

<p>Applications N-Boc-L-cis-4,5-Methanoprolineamide is an intermediate used to prepare methanoprolinenitrile-contg. dipeptide mimetics as DPP-IV inhibitors and as antidiabetic agents.<br>References Magnin, D., et al.: J. Med. Chem., 47, 2587 (2004)<br></p>

<p>Applications A Boc-protected bifunctional linking reagent.<br>References Jimenez-Castells, C., et al.: Bioorg. Med. Chem. Lett., 17, 5155 (2007), Carmona, S., et al.: Mol. Pharm., 6, 706 (2009), Nagahori, N., et al.: Biochem., 48, 583 (2009),<br></p>

<p>Applications 4-Methoxy-3-nitrobenzonitrile<br></p>

<p>Applications 4-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 4-Methylimidazole is a product which results from the interaction of reducing sugars with ammonia. 4-Methylimidazole showed convulsant activity in animals and is listed as a possible carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969): Cunha, S.C. et al.: J. Food Comp. Anal., 24, 609 (2011); Chan, P.C. et al.: Arch. Toxicol., 82, 55 (2008);<br></p>

<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>

<p>Applications (2-hydroxy-4-methoxyphenyl)(4-methylphenyl)methanone (cas# 1641-17-4) is a useful research chemical.<br></p>

<p>Applications A compound contents in musts and wines from Vitis vinifera variety Cabernet Sauvignon.<br>References Murray, K., et al.: J. Sci. Food Agric., 26, 973 (1975), Maga, J., et al.: Food Rev. Int., 8, 479 (1992), Allen, M., et al.: J. Agric. Food Chem., 43, 769 (1995),<br></p>

<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>

<p>Applications Methyl 5-(Ethylsulfonyl)-2-methoxybenzoate (cas# 62140-67-4) is a useful research chemical.<br></p>

<p>Applications 5-Amino-6-methylbenzimidazolone<br></p>

<p>Applications 1-Bromo-3-methylbutane, is used as an extraction solvent to determine various polycyclic aromatic hydrocarbons in water samples though dispersive liquid-liquid microextraction along with GC-MS (gas chromatography- mass spectrometry).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rezaee, M., et al.: J. Chromat. A., 1116, 1 (2006)<br></p>

<p>Applications N-(5-Methyl-3-isoxazolyl)benzenesulfonamide is used in the preparation of isoxazolecarboxylic acid derivatives as agricultural fungicides.<br>References Gomes, J.R.B., et al.: Tetrahedron, 61, 2705 (2005),<br></p>

<p>Applications 3-Methoxy-2',4',6',4-tetrahydroxychalcone piperidine complex (cas# 52218-19-6) is a useful research chemical.<br></p>

<p>Applications 2-Methyl-d3-propyl-3,3,3-d3 Alcohol (CAS# 72182-69-5) is a useful isotopically labeled research compound.<br></p>

<p>Stability Volatile<br>Applications 3-ETHYL-3-METHYLHEPTANE (cas# 17302-01-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Intermediate for the preparation of Naratriptan and other indole sulfonamide derivatives.<br></p>

<p>Applications N-Methylaniline is used as an additive in gasoline because of its antiknock properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Li-jun, et al.: Huaxue Shiji, 37(1), 53-55, 96 (2015); Qin, Li-xia, et al.: Guangzhou Huagong, 43(8), 138-139, 148 (2015);<br></p>

<p>Applications L-Hydroxyprolylglycine_x000D__x000D (cas# 7672-35-7) is a useful research chemical.<br></p>

<p>Applications 2-Methoxyphenylsulfate is used in the analysis of alkylsulfatases and their kinetics.<br>References Bateman, T. et al.: Biochem. J., 236, 401 (1986);<br></p>

<p>Stability Temperature Sensitive<br>Applications Precursor of Diazomethane. It has a cytotoxicity effect.This product contains an undetermined amount of water.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970), Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975),<br></p>

<p>Applications 2,6-Di-(tert-butyl-d9)-4-methylphenol-3,5-d2,OD (CAS# 64502-99-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Amino-3-methylpyridine is used in the synthesis of ketones from aldehydes.<br>References Jun, C. et al.: J. Org. Chem., 62, 1200 (1997); Jun, C. et al.: Angew. Chem. Int. Ed., 37, 145 (1998);<br></p>

<p>Applications 4-(4-Chloro-2-methylphenoxy-d3)butyric Acid (CAS# 1219803-42-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Acetyl-S-(3-hydroxypropyl)-L-cysteine Dicyclohexylamine Salt (unlabelled) (CAS# 14369-42-7) is a useful research compound.<br></p>

<p>Applications 3,4-Dihydroxy-5-methoxybenzoic acid (cas# 3934-84-7) is a useful research chemical.<br></p>

<p>Applications 5,6-Dihydro-5-methyluridine (cas# 23067-10-9) is a useful research chemical.<br></p>

<p>Applications DL-Proline is the racemic mixture of both L-Proline (P755995) and D-Proline (P755990).<br>References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);<br></p>

<p>Applications Ac-lys(ac)-oh was used in the reaction of HOCl with amino acids and peptides with ESR evidence for rapid rearrangement and fragmentation reactions of nitrogen-centered radicals.<br>References Hawkins, C., et al.: J. Chem. Soc. Perkin Trans. 2, 9, 1937 (1998);<br></p>