Amino Acids (AA)

<p>Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH is a molecule that can be used to generate an antigen against tumor necrosis factor alpha (TNFα). It has been shown to be able to bind TNFα and prevent it from binding to its receptors. This leads to a decrease in the production of cytokines, as well as a decrease in the activation of cytosolic guanylate cyclase. Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH has also been shown to inhibit the proliferation of cancer cells by inhibiting extracellular Ca2+ influx and cytosolic Ca2+ ion concentrations.</p>

<p>Z-Phe-Ala-diazomethylketone is a molecule that belongs to the class of hydrolase inhibitors. It has been shown to have inhibitory properties against trichomonas vaginalis and proteolytic activity against liver cells. Z-Phe-Ala-diazomethylketone also has a kinetic energy of 11.2 kcal/mol, which is higher than most protease inhibitors. This molecule has been shown to be effective as a cell vaccine in wild-type mice and as a protease inhibitor in brain cells. The optimal ph for this molecule is 7.5, which corresponds to its pKa value of 5.1.</p>

<p>Please enquire for more information about Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Bz-Asn-Gly-Thr-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trifluoroacetate salt</p>

<p>Please enquire for more information about (Tyr0)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Ala-Ala-Pro-Ala-OH is a tetrapeptide that inhibits elastase, an enzyme that breaks down elastin. This compound has been shown to have anti-elastolytic activity in vitro and in vivo. H-Ala-Ala-Pro-Ala-OH was administered intraperitoneally to hamsters with induced emphysema, resulting in a decrease of elastin abnormalities and improvement of the ultrastructure of the lungs. It also improves pancreatic morphology and function in porcine pancreatitis models.</p>

<p>Please enquire for more information about HIV-1 rev Protein (34-50) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polymyxin B is a cationic detergent that binds to bacterial membranes and destroys the cell wall. Polymyxin B has been shown to be a potent antagonist of spermatozoa and microglia, which are cells that maintain the homeostasis of the central nervous system. It also has been shown to be an inhibitor of chemotaxis in polymorphonuclear leucocytes (PMN), which are white blood cells that participate in inflammatory processes. Polymyxin B has been shown to have chemotactic activity for PMN and inhibit protein synthesis in mitochondria. This compound also inhibits chelerythrine, a cyclase inhibitor that is used as an antineoplastic agent.</p>

<p>HIV is a type of virus that causes AIDS. HIV infects the cells of the human immune system, destroying them and making the body vulnerable to infections from other types of viruses and bacteria. The gp120 protein is an envelope glycoprotein that mediates binding to the CD4 receptor on host T-helper cells and induces fusion of viral and cellular membranes. The gp120 protein has been studied using a variety of methods, including neutralizing antibody binding experiments, enzyme-linked immunosorbent assays (ELISA), Western blotting, peptide mapping, and density lipoprotein binding assays. This fragment contains residues 308-331 in a human immunodeficiency virus (HIV) type 1 gp120 protein.</p>

<p>Please enquire for more information about ([13C6]Leu10)-CRF (human, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Nocistatin (bovine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy-5-methylisoxazole (3HM) is a bacterial strain that belongs to the class of slow-release antibiotics. It is designed to release its active form, 3-hydroxy-5-methylisoxazole carboxylic acid, over time. The release process can be controlled by the ratio of 3HM and citric acid in the solution and by temperature changes. Titration calorimetry has shown that 3HM releases heat when it interacts with hydrochloric acid in a reaction solution. The detection sensitivity for this compound is 0.1 μM, which is lower than that for most other compounds of this type. Optimum concentrations are between 10 μM and 20 μM with a kinetic data of 0.0004/s at 20 μM concentration and an analytical method using vitro assays.</p>

<p>Please enquire for more information about H-Gln(Trt)-2-chlorotrityl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Arg-Glu-OH is a small molecule that is used as a pharmacological agent for the treatment of diabetes. It has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory mediators such as prostaglandin E2 and nitric oxide. H-Arg-Glu-OH also induces apoptosis in human monocytes and macrophages by binding to toll-like receptor 4 (TLR4) on the cell surface. This binding activates NFκB and JNK pathways, leading to the induction of apoptosis. H-Arg-Glu-OH binds with high affinity to monoclonal antibodies against glutamic acid and glycine, which are not present in humans. The compound may be toxic at a neutral pH because it is highly reactive due to intramolecular hydrogen bonding between carbonyl oxygens and amide hydrogens.</p>

<p>pTH (1-31) amide is a polymer conjugate that is used to treat osteoporosis. It has been shown to be effective in reducing the risk of fracture and increasing bone mineral density in animals. The compound binds to the extracellular domain of the estrogen receptor, altering its conformation and preventing it from interacting with other proteins in the nucleus. pTH (1-31) amide has also been shown to reduce blood pressure in animals by inhibiting angiotensin-converting enzyme. Clinical data on this drug are limited, but it has been well tolerated so far.</p>

<p>Please enquire for more information about (Nle 13,Glu14)-Motilin (human, porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(S)-1-Phenyl-2-propanol is a chiral, enantiopure alcohol that is used as a substrate for the preparation of various drugs. It can be prepared by the reduction of (R)-1-phenyl-2-propanol with sodium borohydride. To obtain the desired product, high substrate concentrations are required. Molecular modeling and bioreactor studies have shown that this process can also be carried out in cells. Subtilis sps. were found to be suitable for this process due to their ability to synthesize (S)-1-phenyl-2-propanol from 6-phosphate and l-tert-leucine in a stepwise manner. The use of subtilis sps. may reduce the cost and time needed for production of (S)-1-phenyl-2-propanol because it does not require expensive starting materials or purification steps.END&gt;&gt;</p>

<p>Please enquire for more information about H-Ile-2-chlorotrityl resin (200-400 mesh) (Low Substitution) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Substance P is a neuropeptide that is found in the central nervous system. It is also found in the gastrointestinal tract and plays a role in the regulation of smooth muscle contraction. Substance P has been shown to be involved in inflammatory responses, immune responses, and regulation of water and electrolyte balance. The maximal response of substance P occurs at concentrations between 0.1 to 1 nM and its inhibitory effect on the apical Ca2+ response occurs at concentrations between 10-100 nM. In addition, substance P has been shown to have an excitatory effect on 5-HT7 receptors with subunit composition GluN1/GluN2A/GluN2B/GluN3A/5-HT7(H).</p>

<p>Please enquire for more information about AMCA-Glu-Glu-Lys-Pro-Ile-Ser-Phe-Phe-Arg-Leu-Gly-Lys(biotinyl)-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Adipokinetic hormone G is a peptide found in the hemolymph of Gryllus bimaculatus, a species of cricket. It has been shown to have anti-lipemic and antilipaemic effects in animal models. Adipokinetic hormone G can be detected by bioassay and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.</p>

<p>Nectofibrin Hexapeptide is a peptide that interacts with the antigen-binding site of an antibody. It has been shown to be able to bind to the ovary cells of rats and may have diagnostic value in autoimmune diseases such as idiopathic thrombocytopenic purpura. The sequence of this molecule is Arg-Gly-Asp, which shows complementarity with the receptor binding site on the ovary cells. This peptide could be used for immunotherapy or diagnostics in autoimmune diseases.</p>

<p>Please enquire for more information about HIV Protease Substrate III-B (Native Sequence) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Leu-Phe-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Gly-Arg-Gly-Glu-Ser-Pro-OH is a peptide fragment of collagen that has been used in research to study the effects of this protein on fibrosis, bowel disease, and autoimmune diseases. It has also been found to be able to activate stem cells and is being studied for its application as a cell factor. This peptide fragment inhibits the growth of Candida glabrata by stimulating the production of growth factors such as β1 and colony stimulating factor. It also stimulates the production of integrin receptors, which are important for cell adhesion. H-Gly-Arg-Gly-Glu-Ser-Pro-OH has also been shown to have an antiviral effect in vivo models.</p>

<p>Please enquire for more information about Z-Gly-Pro-Arg-4MbNA acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 is a peptide hormone that is involved in the regulation of water balance and blood pressure. It is a vasoconstrictor and has been shown to have an inhibitory effect on cellular targets such as soluble guanylate cyclase, which are involved in the synthesis of cGMP. Vasopressin 3-mercaptopropionyl-Tyr-Phe-Val-Asn-Cys Pro D Arg Gly NH2 also binds to the oxytocin receptor, which may be responsible for its vasodilatory effect.</p>

<p>H-Gly-Gly-Glu-OH is a hydrolysate of the proteasome peptide. It has reversed-phase and liquid chromatography properties, which make it a useful biochemical tool for the analysis of proteins. The carboxylate group at the end of H-Gly-Gly-Glu-OH can be used as an isopeptide to determine the sequence of peptides that are synthesized by a prokaryotic or eukaryotic cell. H-Gly-Gly-Glu-OH can also be used to cleave ligation products in order to analyse them.</p>

<p>Boc-Pro-Leu-Val-OMe is a peptide analog of Dolastatin 10 which has been shown to inhibit the production of ATP in mitochondria. The compound binds to the active site of bacterial topoisomerase IV, and this binding prevents the enzyme from cleaving DNA. Boc-Pro-Leu-Val-OMe is a small molecule that has an intramolecular structure, and it interacts with DNA to form a stable complex.</p>

<p>H-Leu-Trp-Met-Arg-Phe-Ala-OH acetate salt is a synthetic amino acid. It has been shown to be a substrate for peptidases and proteolytic enzymes, including serine protease. H-Leu-Trp-Met-Arg-Phe-Ala-OH acetate salt also has catalytic activity, which leads to the formation of methyl ketones. This product is used as an analytical reagent in the determination of specificities of proteolytic enzymes. It is also used to measure the activity of amyloid protein and peptidases.</p>

<p>Used in treatment of nonspecific ulcerative colitis</p>

<p>Please enquire for more information about (R)-methyl pyrrolidine-3-carboxylate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-Tyr-NH2 acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Val-Pro-OtBu·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Vasonatrin Peptide (VNP) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Atrial Natriuretic Factor (3-28) (human, bovine, porcine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Ala-Tyr-Ala-OH is a peptidomimetic that has shown promising anti-inflammatory and anticancer properties. It has been found to inhibit the proliferation of human cancer cells and to suppress the growth of human tumor xenografts in mice. It also has shown an ability to cross the blood brain barrier, which may be due to its high lipophilicity. H-Ala-Tyr-Ala-OH inhibits the production of inflammatory cytokines, such as TNFα, IL1β, IL6, and IL8, by inhibiting NFκB activation in immune cells. This inhibition leads to decreased inflammation and fibrosis in various tissues. H-Ala-Tyr-Ala-OH is also active against bacteria and viruses, which may be due to its low molecular weight.</p>

<p>Please enquire for more information about Boc-D-Asp-OFm including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-His(Bzl)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Des-Tyr1-Met-Enkephalin H-Gly-Gly-Phe-Met-OH is a peptide that is derived from the endorphin family. It has been shown to have both amnestic and enkephalin effects, which may be due to its antagonistic effect on naloxone. This endogenous peptide has been studied in a dose response curve, with an increase in amnesia and decrease in memory retention as the dose increases. Des-Tyr1-Met-Enkephalin H-Gly-Gly-Phe-Met-OH also binds to receptors at the same sites as other substances such as epinephrine, β endorphin, and behavioral effects are observed.</p>

<p>Please enquire for more information about Tyr-Leptin (26-39) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-FAM-Woodtide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trifluoroacetate salt</p>

<p>Please enquire for more information about (D-Ala2)-Dynorphin A (1-9) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Ala-Phe-pNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fibronectin fragment (196-203) H-Ser-Arg-Asn-Arg-Cys-Asn-Asp-Gln, is a synthetic peptide that has been shown to have antiinflammatory properties. It can inhibit the inflammatory response by inhibiting the production of cytokines and chemokines. Fibronectin fragment (196-203) H-Ser-Arg-Asn-Arg-Cys-Asn, has also been shown to inhibit angiogenesis and tumor growth in vitro, as well as stabilize blood vessels and reduce the incidence of lymphatic vessel leakage. This peptide may be used in cancer therapy and for other diseases such as Kaposi's sarcoma, rheumatoid arthritis, autoimmune diseases, or infectious diseases.</p>

<p>Please enquire for more information about Ac-Asp-D-Gla-Leu-Ile-b-cyclohexyl-Ala-Cys-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-5-chloro-3-methylbenzoic acid (ACMB) is a substructure of the insecticidal compound chlorantraniliprole. It is a solid at room temperature and has a molecular weight of 142.15 g/mol. ACMB can be extracted from n-hexane, chlorantraniliprole, or xylene using gravimetric analysis. The bioactivity of ACMB can be determined by an anthranilic assay, while its solubility data are available in the literature. ACMB has been shown to have insecticidal activity against lepidoptera larvae and cyanuric activity against mosquito larvae.</p>

<p>L-Alanine methyl ester HCl is a compound that is used in wastewater treatment. It has been shown to inhibit the enzyme DPP-IV, which is associated with metabolic disorders. L-Alanine methyl ester HCl also has been shown to have antimicrobial activity against a number of bacteria, including methicillin resistant Staphylococcus aureus (MRSA). L-Alanine methyl ester HCl has been shown to have anti-inflammatory properties and can be used for the treatment of autoimmune diseases. This compound also has a significant effect on biological properties such as phase transition temperature and thermal expansion.</p>