Amino Acids (AA)

<p>N3-PEG(45)-OH is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, N3-PEG(45)-OH is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>Bosentan is a potent inhibitor of the uptake of organic anions. It is used in the treatment of pulmonary arterial hypertension and has been shown to be effective against pravastatin-resistant HIV protease inhibitors, such as saquinavir, quinidine, and rosuvastatin. Bosentan inhibits uptake by binding to the transporter protein at a site that does not overlap with the binding site for organic anion substrates. This leads to a change in kinetic parameters for substrates, such as pravastatin and saquinavir. The binding site on bosentan may also be elucidated through monolayer experiments with efflux transporters.</p>

<p>Please enquire for more information about 8-Fluoro-6-methoxy moxifloxacin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N,N-bis(Carboxymethyl)-L-glutamic acid is a synthetic compound that functions as a disinfectant. It has been shown to be effective against bacteria and fungi in vitro, with an efficacy of over 90%. N,N-bis(Carboxymethyl)-L-glutamic acid is used as a treatment for tumors due to its ability to penetrate the tumor cells and inhibit fatty acid uptake. This compound also prevents the formation of new blood vessels by inhibiting the synthesis of DNA and RNA. N,N-bis(Carboxymethyl)-L-glutamic acid can be used in coatings for metals or metal surfaces that are exposed to water or air because it is biodegradable and noncorrosive.</p>

<p>7-Fluoro-2-methylquinoline is a multistep synthetic compound that belongs to the family of quinoxalines. It has been shown to have potent antibacterial activity against a wide range of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 7-Fluoro-2-methylquinoline was developed as an analog of the natural product quinoxaline. The key step in its synthesis is the reaction between an aldehyde and hydroxyalkylating reagent in the presence of iron catalyst. This process results in the formation of functional groups such as hydroxyls, alkoxy, or halogens.</p>

<p>Please enquire for more information about H-Glu(Gly-OH)-OH trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>DL-alpha-Methyl-m-tyrosine (AMT) is a drug that is used to treat Parkinson's disease. It is an inhibitor of the uptake of dopamine and norepinephrine, which are neurotransmitters in the central nervous system. AMT blocks the action of a specific enzyme called aromatic L-amino acid decarboxylase, preventing the conversion of these neurotransmitters into their inactive metabolites. AMT also has been shown to be an antidepressant drug with stimulant properties. This may be due to its ability to inhibit uptake and release of monoamines in brain tissue.</p>

<p>Boc-glu(OFm)-OH is a synthetic, cyclic, amide-type molecule that has been shown to reversibly inhibit the activity of purine nucleoside phosphorylase. Boc-glu(OFm)-OH is an affinity ligand for caco-2 cells and has been used in the development of vaccines for porcine rotavirus. This compound has also been shown to have neutralizing effects on both enteroviruses and adenoviruses. The structure of Boc-glu(OFm)-OH is highly structured and it can be prodruged into a variety of analogues with different pharmacological profiles.</p>

<p>Decanoyl-arginine-arginine-leucine-chloromethylketone trifluoroacetate salt is a prohormone that is biosynthesized from the amino acid decanoic acid. It has been shown to inhibit fatty acid synthesis and mineralization in tissue samples, as well as drug target enzymes such as human pathogens. Decanoyl-arginine-arginine-leucine-chloromethylketone trifluoroacetate salt has also been shown to have insulin resistance properties and may be used for the treatment of metabolic disorders.</p>

<p>Please enquire for more information about N-Phenylbenzene-1,3-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Tryptophan methyl ester hydrochloride is an allylation product of L-tryptophan, which is a precursor to serotonin and melatonin. It is used in the synthesis of benzodiazepine receptor ligands and has serotonergic activity. L-Tryptophan methyl ester hydrochloride can be synthesized from L-tryptophan by amination reaction with methylamine and formaldehyde in the presence of a base. This chemical compound was also shown to have antitumour activity against MDA-MB231 breast cancer cells, which may be due to its ability to inhibit cell proliferation.</p>

<p>L-Alanyl-L-proline tert-butyl ester (LAP) is a potent inhibitor of proteases, including angiotensin converting enzyme (ACE), and can be used as an antihypertensive drug. LAP binds to the active site of the ACE and blocks the conversion of angiotensin I to angiotensin II. This inhibition leads to a reduction in blood pressure. LAP has been shown to inhibit the activity of other proteases such as cathepsins, chymotrypsin, trypsin, elastase, and papain. LAP also has potential for use as an anticancer agent due to its ability to inhibit cancer cell growth by blocking protein synthesis at the ribosome level.</p>

<p>Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Phenylalanine betaine is a naturally occurring amino acid that is found in food. Phenylalanine betaines are used as a model system for studying the effects of hydroxyl groups on protein structures and functions. It can be found in urine samples, which indicates its presence in the body. The molecular modeling of phenylalanine betaine has shown that it can function both as an amino acid and a beta-hydroxy acid. Its inhibition constant is 3.5 µM, which indicates that it may have an antibacterial activity.</p>

<p>Please enquire for more information about (4S)-3,4-Dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1,1-dioxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methylthio-trans-zeatin is a naturally occurring sulfur containing compound found in plants. It has been shown to modulate the plant’s defense system, inducing the formation of nodules on the roots and increasing resistance against diseases. 2-Methylthio-trans-zeatin can also be used for bioanalytical purposes, as it can be used to detect other isomers of 2-methylthio-trans-zeatin. The compound can be detected by a number of methods such as mass spectrometry or chromatography. 2-Methylthio-trans-zeatin has been shown to inhibit bacterial growth by binding to the enzyme adenylyltransferase, which is essential for DNA replication. This mechanism of action is similar to that of quinolones, which are commonly used antibiotics.</p>

<p>Please enquire for more information about Fmoc-a-Me-Asn-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-2,6-dichloro-L-phenylalanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-[5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,5'-(1-Methylethylidene)-bis-[1,1'-(bisphenyl)-2-ol] (BPE) is an organic compound that is used in coatings. BPE has a high thermal expansion coefficient and can be used as a plasticizer to make polymers more flexible. BPE hydrolyzes under acidic conditions to produce mercaptoacetic acid, which is corrosive and toxic. It also reacts with proteins, like albumin, at pH 7.4. In wastewater treatment systems, BPE can react with chlorine at a rate of 3% per day to form chlorobenzene, which is known to cause cancer in humans. The use of BPE in the bioreactor process leads to the release of reactive functional groups that are not easily degraded by microbes. In addition, it has been shown that this chemical binds to nuclear hormone receptors and has estrogenic effects on animals.</p>

<p>C-type Natriuretic peptide is a peptide hormone that causes vasodilation, diuresis, and natriuresis. It is secreted by the heart and kidneys in response to volume overload. C-type Natriuretic peptide has been shown to cause fibrosis of the kidney as well as other tissues in mice. The binding of C-type Natriuretic peptide to its receptor activates cyclase, which converts ATP into cAMP. This leads to increased levels of cGMP, which causes smooth muscle relaxation and vasodilation.</p>

<p>Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH trifluoroacetate salt is a fluorescent marker that can be used in immunohistochemical staining. It binds to endogenous vasoactive intestinal peptide, calcitonin and other proteins in tissues and can be detected using immunostaining. Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH trifluoroacetate salt is optimised for use as a substrate for neutral endopeptidase and metalloendopeptidase enzymes, which are responsible for the degradation of vasoactive intestinal peptide.</p>

<p>Please enquire for more information about L-Cysteine-glutathione disulfide trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pyr-Pro-Arg-pNA hydrochloride salt is a chromogenic substrate that is used to detect microorganisms in the blood. This substrate is activated by the enzyme ochraceous, which catalyzes the hydrolysis of pyr-pro-arg-pNA. The reaction produces hydrogen peroxide and an orange color. Pyr-Pro-Arg-pNA hydrochloride salt can be used as an anticoagulant for blood plasma samples. It can also be used to identify Aspergillus ochraceus, a fungus that causes pulmonary infections in humans. Aspergillus ochraceus has been shown to produce this enzyme and to have a high affinity for this substrate.</p>

<p>Please enquire for more information about Boc-Met-Gly-OSu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methyl-L-cysteine hydrochloride is a synthetic molecule that is used as an organic solvent. It can be produced from the reaction of an inorganic base with an ester hydrochloride and has been shown to have stereoselective properties. The spontaneous formation of this molecule was enhanced by the addition of hydrochloric acid, which increased the reaction yield. 2-Methyl-L-cysteine hydrochloride has been shown to react spontaneously with inorganic materials, such as titanium dioxide, which causes a color change from white to yellow.</p>

<p>5-Hydroxy-5-methylhydantoin (5HMH) is a glycosylase that is used to repair damaged DNA. It reacts with the hydroxyl group of 5-methylcytosine and removes it, yielding thymine. The reaction proceeds through a nucleophilic attack on the carbon atom adjacent to the C5 methyl group. This reaction is dependent on neutral pH, uv absorption, and has been shown in vitro to be inhibited by the presence of oxidizing agents. 5HMH has been shown to remove UVB-induced damage from DNA in mammalian cells, which may lead to cancer.</p>

<p>Please enquire for more information about Disodium (1-methyl-4-oxoimidazolidin-2-ylidene)phosphoramidate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(methoxymethoxy)-L-phenylalanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Fmoc-4-bromo-L-tryptophan including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl2-(acetylamino)-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,6-Dimethyl-4-phenylpyronium tetrafluoroborate is a high quality reagent that is useful for the preparation of complex compounds. It is also a useful intermediate and building block. The CAS No. 97606-13-8, 2,6-Dimethyl-4-phenylpyronium tetrafluoroborate has been used in research chemicals and as a versatile building block for the synthesis of speciality chemicals. This reagent can be used in reactions to form many organic molecules that are not commercially available or difficult to synthesize.</p>

<p>Please enquire for more information about 1-Phenyl-4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-[(1-Methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole is a reactive heterocyclic compound. It is a carboxylic acid and an amide with a peptic and cephalalgic effect. The symptoms of 5-[(1-methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole are hemicrania and amnesia. It has been expressed in the calf thymus DNA.</p>

<p>Please enquire for more information about 5-Amino-4-methyl-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>[[4-[[2-(4-Cyclohexylphenoxy)ethyl]ethylamino]-2-methylphenyl]methylene]malononitrile (CAS #: 68436-91-7) is a reactive chemical species that has been used as a crosslinking agent and an uv absorption dye. CEM is a styryl dye that absorbs radiation in the uv range, with a maximum absorption at about 275 nm. It is a substrate film for light emission and can be used to measure viscosity. CEM is also chemically related to aromatic hydrocarbons and fatty acids, and can be synthesized from hydroxyl groups.</p>

<p>7-[(2S,3R)-3-Amino-2-methyl-azetidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-quinoline-3-carboxylic acid (ABT) is a drug that binds to bacterial enzymes and inhibits their ability to synthesize proteins. ABT is a conjugate of fluoroquinolone and an amino acid. As the drug is degradable by hydrolysis, it has been shown to be less toxic in Sprague Dawley rats than other fluoroquinolones. This drug has been used in diagnostic tests as a ligand for affinity ligands, but has not been approved for human use. The drug also possesses functional groups that are important for binding to reconstituted enzymes.br&gt;br&gt;ABT's ester linkages are degradable by hydrolysis and can be</p>

<p>Phospho-L-arginine is a derivative of arginine.</p>

<p>2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.</p>

<p>Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].</p>

<p>Please enquire for more information about N-Me-D-Gln-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-Phe-Arg-4MbNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Boc-Asn-Gly-OEt is a reactive propionate that has been shown to be an antioxidant and to inhibit the formation of reactive oxygen species. The molecule is d-alanine, which is a pharmacophore for the enzyme racemase. Boc-Asn-Gly-OEt catalyzes the conversion of L-alanine to D-alanine by racemase, which assists in the biosynthesis of amino acids. It also has an active site that accepts azide, which may be used for protein labeling. Boc-Asn-Gly-OEt has been shown to have enzymatic activity in stearothermophilus and other bacteria.</p>

<p>D-allo-Threoninol is a conformational analogue of threonine. It has been shown to inhibit the growth of Escherichia coli, Bacillus subtilis, and Staphylococcus aureus in vitro. D-allo-Threoninol binds to the enzyme methionine adenosyltransferase (MAT) by forming hydrogen bonds with its amino acid side chains. This binding prevents the formation of the MAT-coenzyme A complex, inhibiting protein synthesis and cell division.</p>

<p>Diethyl ethyl(1-methylbutyl)malOnate is a polypropylene glycol that can be used as a co-monomer with polyethylene glycol (PEG) to produce polylactic acid. This chemical has been shown to have the ability to withstand high temperatures and therefore can be used for recycling plastics. Diethyl ethyl(1-methylbutyl)malOnate is a white powder, which is soluble in water and glycerin. It can be used as an additive in food products, such as leaves, to prevent them from sticking together during processing. Diethyl ethyl(1-methylbutyl)malOnate is also useful in the manufacture of polyethylene glycols, which are often used in pharmaceuticals and cosmetics.</p>

<p>Please enquire for more information about Fmoc-SDMA(Boc)2-ONa including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline (2HAIQ) is a reactive compound that binds to DNA. It has been shown to be a potent inhibitor of the enzyme cytosolic protein kinase C, which plays an important role in regulating cellular metabolism. 2HAIQ also inhibits the activity of enzymes such as hydroxylases and polymerases. The binding of 2HAIQ to DNA is thought to inhibit transcription by preventing RNA polymerase from transcribing DNA. 2HAIQ may also inhibit replication by binding to the dinucleotide phosphate molecule, which is essential for DNA synthesis.</p>

<p>Please enquire for more information about DL-Dopaquinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (2S,3R,6RS)-2-(3-Oxobutyl)-3-methyl-6-[(R)-2-propanal]cyclohexanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>