Amino Acids (AA)

<p>Applications N-Butyl-N-methylnitrosamine, is an nitroso impurity found in “Sartans” , a class of drugs that block the action of angiotensin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications L-Citrulline-d7, is the labeled analogue of L-Citrulline (C535700), which is an amino acid, first isolated from the juice of watermelon, Citrullus vulgaris Schrad., Cucurbitaceae. It is also used in the treatment of asthenia.<br>References Kurtz, et al.: J. Biol. Chem., 122, 477 (1938), Rajantie, J., et al.: J. Pediatr., 97, 927 (1980), Carpenter, T.O., et al.: N. Engl. J. Med., 312, 290 (1985),<br></p>

<p>Applications 2,2'-AZOBIS-(2-METHYLBUTYRONITRILE) (cas# 13472-08-7) is a useful research chemical.<br>Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.<br></p>

<p>Applications DL-Methionine methylsulfonium chloride (cas# 3493-12-07) is a useful research chemical.<br></p>

<p>5-Methylindole-3-acetic acid (5MI3A) is a molecule that has been shown to have antiproliferative properties in bladder cancer cells. 5MI3A binds to the receptor for GABA, which is an inhibitory neurotransmitter. It also inhibits the production of proinflammatory mediators and reactive oxygen species in cancer cells. 5MI3A has anticancer activity in prostate cancer cells and may act by inducing apoptosis and inhibiting cell proliferation. Consumption of 5MI3A may reduce the risk of cancer development by preventing DNA damage from carcinogens, suppressing inflammation, and regulating cell growth through its antagonistic properties.</p>

<p>1-(3,4-Methylenedioxyphenyl) 2-nitropropene (1-MPNP) is a phosphatase inhibitor that is active against gram-negative bacteria by inhibiting enterotoxins and chlamydia. 1-MPNP inhibits the activity of tyrosine phosphatases, which are enzymes that play a major role in bacterial virulence. 1-MPNP competitively inhibits the activity of tyrosine phosphatases and prevents them from catalyzing the hydrolysis of polyphosphate substrates. This inhibition leads to an accumulation of polyphosphates in the bacterial cell membrane, which disrupts its permeability and leads to cell death.</p>

<p>2-Amino-3-methylpyridine is a colorless crystalline compound. It has the molecular formula of CHN and a molecular weight of 115.2 g/mol. 2-Amino-3-methylpyridine has an asymmetric carbon atom, so it is chiral and can be found in two different forms, enantiomers. The intermolecular hydrogen bond between nitrogen atoms is responsible for the high melting point of -40°C. The coordination geometry of group P2 is pyramidal with the nitrogen atom at the apex and two hydrogen atoms bonded to each other on either side of the nitrogen atom at 120° angles. X ray crystal structures have shown that 2-amino-3-methylpyridine exists as a molecule with an acylation reaction mechanism and intramolecular hydrogen bonding. Methanol solvent was used in this study to dissolve 2 amino 3 methyl pyridine because it does not react with copper chloride</p>

<p>Antimicrobial cationic peptide; used for microscopy glass slides coating</p>

<p>1-[3-(Fluoro-Methylphosphoryl)Oxypropyl]Pyrene is a fluorescent derivative of pyrene. It has been used to label DNA and proteins for experiments involving fluorescence. The fluorophores in 1-[3-(Fluoro-Methylphosphoryl)Oxypropyl]Pyrene are activated by laser light, which causes emission of light at a wavelength of 590 nm. The emission spectrum of 1-[3-(Fluoro-Methylphosphoryl)Oxypropyl]Pyrene is sensitive to the environment and changes with chemical modification.</p>

<p>DL-Proline is a biological molecule that has been shown to bind to the DNA binding domains of proteins. This binding can be seen with the crystal structures of DL-proline and protein. The reaction mechanism for DL-proline is as follows:<br><br>DL-Proline + Protein → Proline + Protein<br><br>The equilibrium constant for this reaction is 1.0 at 298 K. The pKa value for the amide group in DL-proline is 4.8, which means that it will react with water and form an amine group at physiological pH levels. DL-Proline has been shown to have metabolic disorders.</p>

<p>7-[5-(Fluoro-methyl-phosphoryl)oxypentyl]-4-nitro-2,1,3-benzoxadiazole is a reactivator of the central nervous system. It is a noncompetitive antagonist at muscarinic receptors and blocks postsynaptic acetylcholine release from cholinergic neurons. It has been shown to have no effect on blood pressure but does cause an increase in locomotor activity in animals. This drug binds to the hippocampal formation and the ventral hippocampus, which are areas of the brain that are involved in memory and spatial navigation. The distribution of this drug postulated to be due to its ability to penetrate micron sized openings in cell membranes.</p>