Amino Acids (AA)

<p>Applications 2,2'-AZOBIS-(2-METHYLBUTYRONITRILE) (cas# 13472-08-7) is a useful research chemical.<br>Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.<br></p>

<p>Applications L-Citrulline-d7, is the labeled analogue of L-Citrulline (C535700), which is an amino acid, first isolated from the juice of watermelon, Citrullus vulgaris Schrad., Cucurbitaceae. It is also used in the treatment of asthenia.<br>References Kurtz, et al.: J. Biol. Chem., 122, 477 (1938), Rajantie, J., et al.: J. Pediatr., 97, 927 (1980), Carpenter, T.O., et al.: N. Engl. J. Med., 312, 290 (1985),<br></p>

<p>Applications N-Butyl-N-methylnitrosamine, is an nitroso impurity found in “Sartans” , a class of drugs that block the action of angiotensin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications DL-Methionine methylsulfonium chloride (cas# 3493-12-07) is a useful research chemical.<br></p>

<p>Gly-Asp-OH is a medicine that has proliferative activity. It is also an immunoregulatory and biologically active substance, which suppresses the production of cytokines IL-10 in mononuclear cells. Gly-Asp-OH is a synthetic compound with medicinal properties. The structure of this compound was elucidated by chemical analysis and spectroscopic methods. It can be used as an anti-inflammatory agent or to prevent cell death induced by necrosis or apoptosis.</p>

<p>Poly epsilon L-lysine HCl is a water soluble, biodegradable, cationic peptide that can be produced via fermentation by Streptomyces albulus. It shows a wide range of antimicrobial activity against microorganisms such as bacteria, yeasts and molds and is stable at high temperatures and under both acidic and alkaline conditions. This non-toxic poly-L-lysine is commonly used as a supplement or preservative in various food, beverage and cosmetics products. It can also be used for microscopy glass slides coating.</p>

<p>2-Amino-3-methylpyridine is a colorless crystalline compound. It has the molecular formula of CHN and a molecular weight of 115.2 g/mol. 2-Amino-3-methylpyridine has an asymmetric carbon atom, so it is chiral and can be found in two different forms, enantiomers. The intermolecular hydrogen bond between nitrogen atoms is responsible for the high melting point of -40°C. The coordination geometry of group P2 is pyramidal with the nitrogen atom at the apex and two hydrogen atoms bonded to each other on either side of the nitrogen atom at 120° angles. X ray crystal structures have shown that 2-amino-3-methylpyridine exists as a molecule with an acylation reaction mechanism and intramolecular hydrogen bonding. Methanol solvent was used in this study to dissolve 2 amino 3 methyl pyridine because it does not react with copper chloride</p>

<p>1-(3,4-Methylenedioxyphenyl) 2-nitropropene (1-MPNP) is a phosphatase inhibitor that is active against gram-negative bacteria by inhibiting enterotoxins and chlamydia. 1-MPNP inhibits the activity of tyrosine phosphatases, which are enzymes that play a major role in bacterial virulence. 1-MPNP competitively inhibits the activity of tyrosine phosphatases and prevents them from catalyzing the hydrolysis of polyphosphate substrates. This inhibition leads to an accumulation of polyphosphates in the bacterial cell membrane, which disrupts its permeability and leads to cell death.</p>

<p>(1R,2S,3S,5S)-3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylicacid methyl ester is a molecule that has been shown to be effective in lowering the symptoms of Parkinson's disease. It also prevents the uptake of dopamine and serotonin in the brain by binding to dopamine and serotonin transporters on the cell membrane. This drug has been shown to be safe at doses up to 100 mg/kg/day in rats, but has not been tested in humans. The drug is stable in neutral pH environments and does not degrade upon exposure to light or oxygen.</p>

<p>2-Methoxy 17b-estradiol is a synthetic estrogen that binds to DNA and alters the transcriptional process. It has been shown to induce apoptosis by activating the pro-apoptotic protein Bax and inhibiting the anti-apoptotic protein Bcl-2. This drug inhibits the metabolic response of cancer cells to chemotherapy, leading to a decrease in tumor size, and can be used as an implantable device for treating cancer. 2-Methoxy 17b-estradiol also has minimal toxicity in comparison to other estrogens, with no significant cytotoxicity observed in cells of reproductive tissues or endocrine organs, nor any significant toxic effects on liver function tests or serum lipids.</p>

<p>7-[5-(Fluoro-methyl-phosphoryl)oxypentyl]-4-nitro-2,1,3-benzoxadiazole is a reactivator of the central nervous system. It is a noncompetitive antagonist at muscarinic receptors and blocks postsynaptic acetylcholine release from cholinergic neurons. It has been shown to have no effect on blood pressure but does cause an increase in locomotor activity in animals. This drug binds to the hippocampal formation and the ventral hippocampus, which are areas of the brain that are involved in memory and spatial navigation. The distribution of this drug postulated to be due to its ability to penetrate micron sized openings in cell membranes.</p>