Amino Acids (AA)

<p>Applications 3-MERCAPTO-4-METHYL-4H-1,2,4-TRIAZOLE (cas# 24854-43-1) is a useful research chemical.<br></p>

<p>Applications N,N-Diisopropyl-3-(2-methoxy-5-methyl-phenyl)-3-phenylpropylamide-d14 (cas# 1795013-34-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-(2-Methyl-1,3-dioxolan-2-yl)-6-methylpyridine is used in the synthesis and biological activity of metabolites of the antidiabetic, antihyperglycemic agent Pioglitazone (P471000).<br>References Defronzo, R., et al.: Diabetes, 1988, 37, 667 (1988), Hulin, B., et al.: J. Med. Chem., 35, 1853 (1992), Iwanishi, M., et al.: Metabolism, 42, 1017 (1993),<br></p>

<p>Applications N6-(2-Chloro-6-methyl-4-pyrimidinyl)-2-methyl-4,6-quinolinediamine is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.<br>References Gao, Y., et. al.: Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al.: Methods Enzymol, 406, 554 (2006)<br></p>

<p>Applications Labelled Furan-3-methanol. Furan-3-methanol is used in the synthesis of potentially prebiotic RNA precursors: adenine and uracil derivatives.<br>References Pavey, J.B.J., et al.: Tetrahedr. Lett., 36, 2657 (1995),<br></p>

<p>Applications 1-Methyldibenzothiophene, is an alkyldibenzothiophene present in crude oil. Research concerning the biodegradation of Dibenzothiophene by different types of bacteria is a currently being carried out, as these bacteria have the ability to breakdown other harmful PAH’s as well. This may be used in removing spilled oil from marine and terrestrial environments.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boberg, F., et al.: Erdoel &amp; Kohle, Erdgas, Petrochemie, 47, 187 (1994); Tanaka, Y., et al.: Applied Microbiology and Biotech., 59 (2), 325 (2002); Prince, R., Spill Sci. Tech. Bulletin, 8 (2), 145 (2003);<br></p>

<p>Applications 5-Bromo 3-O-Methyl Colterol is an intermediate used in the synthesis of 3-O-Methyl Colterol (M294570), which is a metabolite of Bitolterol, a new bronchodilator.<br>References Shargel, L., et al.: Drug Metab. Dispos., 4, 72 (1976)<br></p>

<p>Applications (E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone is an intermediate in the synthesis of (E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone Hydrochloride (M725995), which is a piperazinyl phenylethanone compound that acts as an inhibitor of traffic between the trans-Golgi network (TGN) and endosomes that depends on the clathrin adaptor complex AP-1. Additionally, Membrane Traffic Inhibitor, A5 has been shown to have little effect against other trafficking pathways involving endosomes and TGN.<br>References Duncan, M. C., et al.: Proc. Natl. Acad. Sci. U S A, 104, 6235 (2007)<br></p>

<p>Applications Ethyl 5-Methyl-1-phenyl-1H-pyrazole-4-carboxylate (cas# 89193-16-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Methyl-benzenesulfonic Acid 2-[3-(Dimethylphenylsilyl)cyclobutylidene]hydrazide is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.<br>References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);<br></p>

<p>Applications (2E)-3-[[(4-Methylphenyl)sulfonyl]oxy]-2-butenoic Acid Methyl Ester is an intermediate in the synthesis of Juvenile Hormone which (J211195) regulates development, reproduction, diapause, and polyphenisms in insects.<br>References Riddiford, L.: Adv. Insect Physiol., 24, 213 (1994); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>

<p>Applications 2-(4-Ethoxyphenyl)-2-methylpropanol (cas# 83493-63-4) is a useful research chemical.<br></p>

<p>Applications DL-2-Methylbutyric Acid is a common chemical reagent used in the synthesis of anticancer naphthoquinione aliphatic amides. Also used in the synthesis of novel erythromycins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kongkathip, B. et al.: Eur. J. Med. Chem., 60, 271 (2013); Pacey, M. et al.: J. Antibio. 51, 1029 (1998);<br></p>

<p>Applications (Acetonitrile)[4-tert-butyl-2-(diisopropylphosphino)-1-methyl-1H-imidazole-κN,κP](η5-cyclopentadienyl)ruthenium(1+) hexafluorophosphate, is an Alkene Zipper Catalyst, used in selective transformation of a large variety of ω-alkenyl cyclopropylcarbinols into stereodefined unconjugated (E)-acyclic aldehydes .<br>References Bruffaerts, J., Vasseur, A., &amp; Marek, I. (2018). Alkene-Zipper Catalyzed Selective and Remote Retro-ene Reaction of Alkenyl Cyclopropylcarbinol. Advanced Synthesis &amp; Catalysis, 360(7), 1389–1396.<br></p>

<p>Applications 1-[(S)-O-(5-Isoquinolinesulfonyl)-N-methyltyrosyl]-4-phenyl-piperazine (cas# 1391068-10-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methyl-4-nitropyridine (cas# 13508-96-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-[(4-Chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic Acid Methyl Ester-d3 is an intermediate in the synthesis of Isotope labelled Metconazole (M225795), an conazole based fungicide used for the control of black sigatoka disease on banana.<br></p>

<p>Applications Intermediate for the preparation of Isotope Labelled Valdecoxib.<br></p>

<p>Applications 4-Benzyloxy-3-methoxyphenylacetic Acid is a reactant in the synthesis of (+)- and (-)-govadine, which are dopamine D1 and D2 receptor modulators.<br>References Zhai, H., et. al.: Bioorg. Med. Chem. Lett., 22, 1557 (2012)<br></p>

<p>Applications 6-Hydroxy-8-methoxy-octanoic Acid Methyl Ester-d5 is a compound useful in organic synthesis.<br></p>