Amino Acids (AA)

Applications L-Homocysteine Thiolactone Hydrochloride is used to prepare substituted homocysteine analogs as inhibitors of peptidylglycine α-amidating monooxygenase. It is also used to synthesize (mercaptoacyl)alanylprolines as metalloprotease inhibitors.
References Erion, M., et al.: J. Med. Chem., 37, 4430 (1994); Slusarchyk, W., et al.: Bioorg. Med. Chem. Lett., 5, 753 (1995)

Applications 6,6'-Methylenebis(2-(tert-butyl)-4-ethylphenol) (cas# 88-24-4) is a useful research chemical.

Applications L-Alanine-d7 (CAS# 74280-71-0) is a useful isotopically labeled research compound.

Applications: 3-Methyl-2,5-dihydrothiophene-1,1-dioxide is a reagent used in Diels-Alder reactions of butadienylpyridinium bromides.
References Lee, S., et al.: J. Org. Chem., 62, 7812 (1997);

Applications 2,2-Dimethoxy-N-methylethanamine is an impurity formed in the synthetic process of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification,
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),

Applications Labelled L-Glutamine (G597000). L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.
References Rivett, A., et al.: J. Biol. Chem., 260, 300 (1985), Watford, M., et al.: Metabolism, 49, 141 (2000), Wilmore, D., et al.: J. Nutr., 131, 2543S (2001),

Applications 6-Methylquinoline, is a building block used for the synthesis of various pharmaceutical compounds, and biologically active compounds. It can be used for the preparation of pyranobenzopyrone compounds, having anti-norovirus activity.
References Pokhrel, L., et al.: bioorg. Med. Chem. Lett., 22, 3480 (2012);

Applications Zinc Glycinate is used in the preparation of hydroxy acid complexes used in skin antiaging, acne and skin whitening formulations.

Applications It is used as labelled biomarker for metabolic age.
References Selmer, T., et al.: Eur. J. Biochem., 268, 1363 (2001), Connelly, J., et al.: Drug Metab. Dispos., 30, 1357 (2002), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006), Monteagudo, E., et al.: Xenobiotica, 37, 1000 (2007),

Applications N-Methyldiethanolamine-13C,d3 Hydrochloride is isotopically labelled salt form of N-Methyldiethanolamine (M301625), which is used as a reagent in the synthesis of broad-spectrum antimicrobial polycarbonate hydrogels with fast degradability. It is also used as a reagent in the synthesis of dihydroxy quaternary ammonium salts with long chain alkyl bromides that can exhibit antibacterial and antifungal activity.
References Pascual, A., et al.: Biomacromolecules, 16, 1169 (2015); Liu, W., et al.: Chem. Biol. Drug Des., 85, 91 (2015);

Applications 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.
References Sutton, J., et al.: Bioorg. Med. Chem. Lett., 22, 1464 (2012); Lai, Z., et al.: Eur. J. Med. Chem., 83, 547 (2014)

Applications 2-Azido-2-deoxy-D-glucose is a glucose derivative that have been used to study the substrate specificity of galactokinase.
References Zou, W., et al.: Bioorg. Med. Chem. Lett., 22, 3540 (2012);

Applications 4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline (cas# 550-10-7) is used for the antagonism of ABCG4, Lyn kinase, and c-Cbl E3 ligase to increase platelet count as therapy for thrombocytopenia.
References Wang, N., et al.: PCT Int. Appl. 107pp. (2014)

Applications Tris(2-(2-methoxyethoxy)ethyl)amine (cas# 70384-51-9) is a useful research chemical.

Applications 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (cas# 83732-72-3) is a useful research chemical.

Applications 6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.

Applications D-Glutamic acid 1-tert-butyl ester is a protected form of D-Glutamic acid (G596965). D-Glutamic acid is an unnatural isomer of L-Glutamic acid (G596960), and is found in bacterial cell wall peptidoglycan of gram-positive and gram-negative bacteria. D-Glutamic acid also occurs as poly-gamma-Glutamic acid, which is a weak immunogen but is capable of acting as a hapten (a small molecule that induces the production of antibodies, as well as binding to them).
References Dougherty, T., et al.: J. Bacteriol., 175, 111 (1993); Goodman, J. & Nitecki, D.: Immunology, 13, 577 (1967); Robinson, T.: Life Sci., 19, 1097 (1976)

Stability Hygroscopic
Applications Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
References Morita, M., et al.: J. Med. Chem., 38, 2176 (1995), Sakai, T., et al.: J. Med. Chem., 42, 1836 (1999),

Applications N-[(R)-1-Carbethoxybutyl]-(S)-alanine is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)

Applications 5-Methylfuran-2(3H)-one is an aromatic compound responsible for the aroma of caramel, dried and roated nori, wine, and brewed coffee.
References Paravisini, L., et. al.: Flavour Frag. J., 27, 424 (2012); Shu, N., Shen, H.: Flavour Frag. J., 27, 157 (2012); Chin, S., et. al.: J. Chrom. A, 1218, 7487 (2011)

3'-Iodo-4'-methoxyacetophenone is a chemical compound that is used in the synthesis of other organic compounds. It is a byproduct of the reaction between acetophenone and iodomethane. 3'-Iodo-4'-methoxyacetophenone is soluble in most solvents, such as ethanol, ether, chloroform, and acetone. The compound has a CAS number of 79324-77-9.

5-Chloro-DL-tryptophan is an antibiotic that is synthesized from tryptophan. It is used as a precursor for the synthesis of other antibiotics, including 5-chloro-dl-tryptophan and indole. 5-Chloro-DL-tryptophan has been shown to have a significant effect on the synthesis of protein amino acids, such as d-aspartic acid and α-amino acids. The steric properties of 5-chloro-dl-tryptophan are also important in its ability to block protein synthesis. Ozonization can be used to oxidize α,β unsaturated carbonyl compounds found in 5 - chloro - DL - tryptophan.