Proteins

R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes.

Bikunin/AMBP Protein, Human, Recombinant (aa 1-203, His) is expressed in HEK293 mammalian cells with His tag.

Genetic engineers have used glutathione S-transferase to create the GST gene fusion system.

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer.

CD200R Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.

CD19 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CD16b Protein, Human, Recombinant (NA2,His & Avi), Biotinylated is expressed in HEK293 mammalian cells.

CEACAM1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

ACVR2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas.

VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.

As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta,

Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays

FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

IL-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.7 kDa and the accession number is P01586.

Acitretin is a synthetic retinoid that can be used to treat skin conditions such as acne, psoriasis, and eosinophilic fasciitis. It has been shown to be an active inhibitor of squamous cell carcinoma in the laboratory. Acitretin works by inhibiting the excessive cell growth and keratinisation seen in psoriasis therefore reducing the thickening of the skin, plaque formation and scaling.

Rho/MRTF/SRF mediated gene transcription inhibitor

As a synthetic trifluorinated glucocorticoid receptor agonist, Fluticasone exhibits anti-inflammatory properties. When binding to and activating glucocorticoid receptors, Fluticasone initiates the activation of lipocortin which inhibits cytosolic phospholipase A2. Consequently, the cascade of inflammatory mediator synthesis reactions are inactivated and the production of inflammatory cells namely mast cells, dendritic cells, macrophages and eosinophils and the cytokines that they produce are greatly reduced.It is this anti-inflammatory role which has enabled Fluticasone to successfully treat conditions such as asthma, emphysema, allergic rhinitis and atopic dermatitis. It has also been seen to increase anti-inflammatory effects of annexoin-1 and mitogen-activated kinase phosphatase-1; reduce mucus gland secretions and increase the number of beta-2 receptors on smooth muscles of the airways.
Fluticasone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha.

Eplerenone is a drug known as an aldosterone antagonist. It is a type of potassium-sparing diuretic that is used to treat chronic heart failure and high blood pressure, particularly for patients with resistant hypertension due to elevated aldosterone. It does this by blocking the activity of the enzyme that produces aldosterone, which increases levels of sodium and water in the body. This leads to a decrease in blood pressure.

Please enquire for more information about PSA, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pioglitazone is a thiazolidinedione drug that is used in combination with diet change and exercise to treat glycemic levels in patients with type 2 diabetes mellitus. This drug is an agonist of peroxisome proliferator-activated receptor-gamma and increases glucose uptake. In animal studies, Pioglitazone has shown to have anti-inflammatory properties.

Estrogen receptor degrader; therapeutic use in breast cancer

Bexarotene is a retinoid and antineoplastic agent that is used for the treatment of solid tumours and t-cell lymphomas. It inhibits the growth in vitro of some tumor cell lines of hematopoietic and squamous cell origin and research has shown that it induces tumor regression in vivo in some animal models.

Please enquire for more information about PSA, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page

PPARγ antagonist

ALPK1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.

May act as a negative regulator of collagen matrix deposition.