Peptides
Subcategories of "Peptides"
Found 29707 products of "Peptides"
BNP-45 (Rat)
CAS:BNP-45 is a peptide that binds to the beta-subunit of the Na+/K+ ATPase, inhibiting its activity. It is a potent inhibitor of the enzyme and has been used in research as a tool to study ion channels and receptor activation. BNP-45 has been shown to inhibit ion-channel activity by binding to the beta subunit of the Na+/K+ ATPase. This inhibition leads to an increase in intracellular sodium and calcium levels, which may result in a variety of physiological effects.Formula:C213H349N71O65S3Purity:Min. 95%Molecular weight:5,040.7 g/molPhosphoramidon
CAS:Phosphoramidon is a phosphonate compound that inhibits the binding of two enzymes, cholinesterase and butyrylcholinesterase. It has been shown to cause a bronchoconstrictor response in mice, inhibit mesenteric enzyme activities, and inhibit cardiac enzyme activity in rats. Phosphoramidon is used as an experimental drug for treatment of myocardial infarcts. It also has an effect on the central nervous system by acting on neurokinin-1 receptors and kappa-opioid receptors.
Phosphoramidon is a monosodium salt with biochemical properties similar to those of other members of this class of drugs.Formula:C23H32N3O10P•2Na•2H20Purity:Min. 95%Molecular weight:623.5 g/molH-Phe-Leu-Leu-Arg-Asn-OH
CAS:H-Phe-Leu-Leu-Arg-Asn-OH is a β-amino acid that has been shown to have antioxidant properties. It acts as a competitive inhibitor of the enzyme collagenase and has been shown to inhibit the development of atherosclerotic lesions in mice. The amide form of H-Phe-Leu-Leu-Arg-Asn has also been shown to have site specific activity on ventricular myocardium cells, which may be related to its ability to induce cytosolic calcium release. HPLR also has protease activity that can be inhibited by urea nitrogen and β amino acid. Basophilic leukemia cells produce HPLR at high levels and it is thought that this is due to an increased requirement for the production of collagen in these cells. HPLR has been shown to activate thrombin receptors, which are found on the surface of platelets and endothelial cells. Activated thrombinFormula:C31H51N9O7Purity:Min. 95%Molecular weight:661.81 g/molHepcidin (Rat) (Bulk)
Consisting of the following disulfide Bonds: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22, this product is a rat Hepcidin peptide hormone available as a Trifluoroacetate Salt. Hepcidin is a hormone that regulates iron homeostasis in mammals. It is synthesized by hepatocytes and released into the blood, where it binds to ferroportin, expressed on the surface of cells lining the small intestine. Through binding to ferroportin, Hepcidin inhibits ferroportin's function and prevents iron from being absorbed from the gut.Formula:C111H169N31O35S8Purity:Min. 95%Molecular weight:2,712.2 g/molBoc-D-Trp(CHO)-OH
CAS:Boc-D-Trp(CHO)-OH is a synthetic peptide. It is an activator of ion channels and has been used to study the interactions between ligands and receptors. This product is suitable for life science, cell biology, pharmacology, and other research applications. Boc-D-Trp(CHO)-OH can be used as a research tool in studying protein interactions and receptor functions.Formula:C17H20N2O5Purity:Min. 95%Molecular weight:332.35 g/molDoxorubicin hydrochloride
CAS:Doxorubicin is a cytotoxic drug that belongs to the class of anthracyclines. It is used as an anticancer agent and in the treatment of various types of cancer. Doxorubicin has been shown to inhibit glucose uptake by cells, which may be due to its ability to form disulfide bonds with proteins. Doxorubicin also binds to iron-sulfur clusters, causing cell lysis, which may lead to tumor necrosis. In vitro assays have shown that doxorubicin inhibits drug transporter function, leading to reduced cellular uptake of drugs.Formula:C27H29NO11•HClPurity:Min. 95%Molecular weight:579.98 g/molOxyntomodulin, Glucagon-37 (Porcine)
CAS:Oxyntomodulin, a peptide hormone made up of 37 amino acids, is produced and released from gut endocrine L-cells. It has the ability to regulate gastric acids secretion in the gastric oxyntic glands. Oxyntomodulin, Glucagon-37 (Porcine) product is avaiable in the Trifluoroacetate salt form and can be used as an inhibitor of gastric acid secretion and pancreatic enzyme secretion. It has also been shown to reduce food intake and increase energy expenditure in humans. Central injection of oxyntomodulin reduces food intake and weight gain in rodents, suggesting that oxyntomodulin signals food ingestion to hypothalamic appetite-regulating circuits.Formula:C192H295N59O60SPurity:Min. 95%Molecular weight:4,421.92 g/molNeuromedin U8 (Porcine)
CAS:Neuromedin U8 (Porcine) is a peptide that binds to the receptor for Neuromedins. It has been shown to inhibit cell proliferation and induce apoptosis in some cancer cells. Neuromedin U8 has also been shown to have a protective effect on the bowel by inhibiting inflammatory bowel disease. The peptide is also known to be active on other physiological functions and metabolic disorders, such as amide metabolism and hypertrophy, which are due to its conformational properties.
Formula:C54H78N16O10Purity:Min. 95%Molecular weight:1,111.32 g/molH-Ser-Leu-Ile-Gly-Arg-Leu-OH
CAS:H-Ser-Leu-Ile-Gly-Arg-Leu-OH is a peptide that is derived from the amino acid sequence of the Protease Activated Receptor (PAR) and has been shown to be an inhibitor of PAR4. It has been shown to inhibit coagulation, myocardial infarct, cytosolic Ca2+, and receptor activity in vitro. H-Ser-Leu-Ile-Gly-Arg-Leu-OH has also been shown to decrease blood pressure in mice by inhibiting cyclase activity and reducing vascular reactivity.Formula:C29H55N9O8Purity:Min. 95%Molecular weight:657.82 g/molMet-MCA
CAS:Met-MCA is a peptide that can be used as an activator, antibody, or receptor. CAS No. 94367-34-7. It is a high purity product with high quality and good stability in salt solution or in PBS (PH 7.4). It inhibits ion channels and has been shown to inhibit the interactions of proteins. Met-MCA can be used as a pharmacological tool for research on protein interactions and ligand/receptor binding.Formula:C15H18N2O3SPurity:Min. 95%Molecular weight:306.38 g/molN-(4-Biphenylacetyl)-Cys(Me)-D-Arg-Phe-N-Phenylethylamide
CAS:N-(4-Biphenylacetyl)-Cys(Me)-D-Arg-Phe-N-Phenylethylamide is an inhibitor of serine proteases. It prevents the breakdown of proteins, which may result in a number of pathologies. N-(4-Biphenylacetyl)-Cys(Me)-D-Arg-Phe-N-Phenylethylamide has been shown to prevent reperfusion injury and proteinuria in mice by inhibiting renal inflammation and oxidative stress. This compound has also been shown to be effective in preventing the development of cancer, for example prostate cancer, by inhibiting angiogenesis, leading to reduced vascularization.Formula:C41H49N7O4SPurity:Min. 95%Molecular weight:735.96 g/molH-Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly-NH2
CAS:This peptide hormone is a member of the lipid-binding proteins. It is a basic protein that has been found to be expressed in human leukemia cells and may have an important function in cellular transformation. The hl-60 cells, treated with this agent, show changes in cell shape and motility. Epidermal growth factor (EGF) receptors are activated by this fatty acid, which leads to an increase in the production of EGF by the cells. This peptide hormone has been shown to bind to the epidermal growth factor receptor and stimulate the production of EGF. Monoclonal antibodies can be used to identify this peptide hormone. The binding sites for this peptide hormone are dinucleotide phosphate or cytosolic proteins. This peptide hormone has been associated with autoimmune diseases such as rheumatoid arthritis and psoriatic arthritis.Formula:C64H106N22O21Purity:Min. 95%Molecular weight:1,519.69 g/molUrotensin II (Human) Antiserum
Urotensin II (Human) Antiserum is a research tool for the study of ion channels and receptors. Urotensin II is a peptide that interacts with the G-protein coupled receptor, UTA1. The purified antibody can be used to detect the presence of this peptide in a sample by Western blotting or ELISA. This product is supplied in high purity and has not been shown to react with any other protein.
Purity:Min. 95%(Gly-Pro-Pro)7
Gly-Pro-Pro (Gly-Pro-Pro)7 is a peptide that has been shown to inhibit the activity of various proteases, including collagenase and elastase. It also inhibits the activity of matrix metalloproteinases, which are enzymes that degrade collagen and other extracellular matrix proteins. Gly-Pro-Pro (Gly-Pro-Pro)7 is therefore potentially useful for the treatment of diseases involving excessive degradation of connective tissue.
Formula:C84H121N21O22Purity:Min. 95%Molecular weight:1,777.03 g/molFmoc-Thr(tBu)-Wang Resin (100-200 mesh) 1% DVB
Fmoc-Thr(tBu)-Wang Resin (100-200 mesh) 1% DVB is a pharmacological research tool that is used to study protein interactions. It is also used as an inhibitor in the synthesis of peptides and has a high purity. This resin can be used for the production of antibodies, which are antibodies that specifically bind to a particular antigen. Fmoc-Thr(tBu)-Wang Resin (100-200 mesh) 1% DVB is an ion channel inhibitor that blocks voltage gated sodium channels, which are involved in pain transmission.Purity:Min. 95%Pyroglutamylated RFamide Peptide (Human)
RFamide peptides are a family of neuropeptides that are involved in the regulation of appetite and metabolism. Pyroglutamylated RFamide peptide (human) is an inhibitor of the G protein-coupled receptor, which has been shown to activate the Ligand-gated ion channel. The high purity of this product makes it suitable for use in research as well as antibody production.Formula:C199H301N55O65Purity:Min. 95%Molecular weight:4,503.8 g/molGhrelin (Human, 1-18)
Amino acids 1-18 of the 28 amino acid peptide hormone Ghrelin which has various effects on the body, including stimulating appetite, nutrient sensing and meal initiation. It has also been found to regulate insulin resistance, diabetes and obesity and asserts its functional affects through acting as an endogenous ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin is able to associate with the GHS-R due to it containing a unique N-octanoyl group which is linked to its serine 3 residue covalently. Its wider functions such as glucose homeostasis, energy homeostasis, cardio-protective effects, its role in bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases.
Formula:C96H157N31O30Purity:Min. 95%Molecular weight:2,225.51 g/molH-Arg(Pbf)-2-ClTrt-Resin (100-200 mesh) 1% DVB
H-Arg(Pbf)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin used in the synthesis of peptides. This resin contains two amino acid residues that are used to form peptide bonds. These residues can be either H-Arg or H-Lys, but not both. The resin also contains a reagent called 2,4,6-trichlorophenoxyacetic acid (Troc), which reacts with the NH groups on the amino acids to form an ester linkage. The resin is typically used for building blocks and as an intermediate for synthesizing more complex molecules such as peptides and proteins.Purity:Min. 95%Wang Resin (200-400 mesh) 1% DVB
Wang Resin is a resin for peptide synthesis with a high loading capacity. Wang Resin is an unsubstituted polystyrene resin and has been used in peptide synthesis as a solid phase. It can be used as a building block to create other resins or as a solid phase support in peptide synthesis. Wang Resin is also used in the manufacture of pharmaceuticals, agrochemicals, and cosmetics.
Purity:Min. 95%BKT140
CAS:BKT140 is a potent and selective inhibitor of the CXCR4 receptor. It blocks binding of the chemokine stromal cell-derived factor-1α (SDF-1α) to its receptor, inhibiting cellular proliferation and inducing apoptosis in human cancer cells. BKT140 also inhibits the activity of cyclin-dependent kinases, which are enzymes that regulate the progress of cells through the cell cycle.Formula:C97H144FN33O19S2Purity:Min. 95%Molecular weight:2,159.53 g/mol
