Peptides

<p>Peptide H-DRV^YIHPFHL-OH is a heavy labelled form of Angiotensin I peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>HIV-1 p17 Gag (77-85), also called SL9, is a short part of the Human Immunodeficiency Virus 1 especially a short peptide of matrix composed of the viral protein p17 ensuring the integrity of the virion particle. HIV-1 p17 Gag (77-85) HLA-A*02:01-restricted was one of the first cytotoxic T lymphocytes epitope identified for HIV-1. It produces a specific cytotoxic T cells response in 75% of chronically infected adults but a rare activity in acute infection. Therefore, HIV-1 p17 Gag (77-85) may serve as target for anticancer immunotherapeutic strategies especially for vaccine development.<br>Applications of HIV-1 p17 Gag (77-85):<br>HIV-1 p17 Gag (77-85) is used to stimulate CTL responses in peripheral blood mononuclear cells (PBMCs). Then, ELISPOT assay is used to quantify peptide epitope specificity and IFN-γ releasing effector cells.<br>Potential cross-reactivities with FluM1 (58-66) and HCV NS5B (2594-2602):<br>Moreover, HIV-1 p17 Gag (77-85) share similarities with FluM1 (58-66) which can potentially show a cross-reactivity between these epitopes. It has been demonstrated a cross-reactivity and results suggest that immunity following infection by Influenza virus causes specific immune response to HIV-1 p17 Gag (77-85).<br>Similarities between two others HLA-A2-restricted epitopes of two viruses have been demonstrated too: the amino acid sequence of HIV-1 p17 Gag (77-85) (SLYNTVATL) and of HCV NS5B (2594-2602) (ALYDVVTKL). Therefore, researches are conducted to know if during HCV/HIV co-infection it could be exist a T cell cross reactivity.</p>

<p>CNP-53 is a Research Tool for the study of protein interactions, pharmacology and cell biology. It is an activator that interacts with Ligand Receptor and Cell Biology. CNP-53 is a peptide with a molecular weight of 5310.1 Da, which is purified to be 99% pure. This product is suitable for use in research as well as in clinical trials and has been shown to inhibit ion channels and high purity proteins.</p>

<p>Portion of CMV pp65</p>

<p>Angiotensin converting enzyme (ACE) light tryptic peptide standard for use in proteomics studies. ACE is involved in the regulation of blood pressure through converting inactive angiotensin I to active angiotensin II and also degrading active Bradykinin.</p>

<p>Anti NPY (1-19) is a peptide that binds to the NPY receptor. It is an agonist of the NPY receptor, which is a G-protein coupled receptor. This peptide has been shown to activate ion channels, such as nicotinic acetylcholine receptors and glutamate receptors. Anti NPY (1-19) has also been shown to inhibit ligand binding to the NPY receptor, and may be used as a research tool for studying this receptor in cell biology.</p>

<p>The 2'-5' oligoadenylate synthetase 1 (2-5A-1) is a protein that in humans is encoded by the OAS1 gene. This enzyme catalyzes the synthesis of 2'-5' oligoadenylates, which are potent activators of PKC and MAPK. 2-5A-1 has been shown to increase intracellular calcium levels, activate PKC and MAPK, and induce apoptosis in human cells.</p>

<p>H-Leu-D-Leu-OH is a nonproteinogenic amino acid that is used in the biosynthesis of proteins. It is formed from glutamic acid and leucine through an amide bond, and has a protonated amino group. The specificities of H-Leu-D-Leu are not yet known, but it has been shown to have antibacterial activity against Staphylococcus aureus and Streptococcus pyogenes. H-Leu-D-Leu may be transported across the cytoplasm membrane by means of a transport rate that is significantly higher than other amino acids. This amino acid also exhibits significant homology with nanosized molecules.</p>

<p>Homoglutathione is a glutathione analog that contains an extra b-alanine residue. Homoglutathione has been shown to be a potent inhibitor of fatty acid synthesis. It inhibits the activity of the enzyme, acetyl-CoA carboxylase, which catalyzes the conversion of acetyl-CoA to malonyl-CoA. Homoglutathione also binds to and inhibits cytoplasmic proteins, such as glutamine synthetase and glutamate synthase. The binding of homoglutathione to these proteins prevents the formation of the active site by preventing the hydrogen bonding between amino acid residues. This process is important in energy metabolism because it regulates the production of ATP from ADP and phosphate.</p>

<p>DBCO-dPEG®12-Meso-TP-IR775 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DBCO-dPEG®12-Meso-TP-IR775 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Anti-C-Peptide I (Rat) Serum is an inhibitor of the C-peptide receptor. It can be used as a research tool to study the activation of the peptide receptor and its interactions with other proteins. Anti-C-Peptide I (Rat) Serum is also an excellent reagent for antibody detection, with high purity and good quality.</p>

<p>Biotin-dPEG®11-Oxyamine HCl is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®11-Oxyamine HCl is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Biotin-dPEG®23-Azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®23-Azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Mouse antibody against the human sequence of the enzyme Acyl-coenzyme A thioesterase 11 (StAR-related lipid transfer protein 14 or STARD14). Acyl-coenzyme A thioesterase 11 is part of the thioesterase family of enzymes that have roles in regulating levels of Coenzyme and intracellular fatty acids.</p>

<p>This Thyroglobulin Heavy Tryptic Peptide Standard is useful in protein identification and quantitation studies such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The use of tryptic peptides overcomes the challenges of quantifying serum thyroglobulin levels using immunoassays through removing the risk of interferences from Thyroglobulin antibodies. Thyroglobulin is a thyroid hormone production substrate and thus an important biomarker for differentiated thyroid cancer.</p>

<p>Big Endothelin-2 is a 38 amino acid peptide formed as a result of furin cleavage of proendothelin which in turn is produced from EDN2 gene transcription. Due to the actions of the Endothelin-Converting Enzymes: ECE-1 and ECE-2, Big Endothelin-2 is converted into Endothelin-2 (ET-2) peptide. ET-2 has affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure. This product has is available as a 0.1mg vial.</p>

<p>Insulin II is a peptide hormone that is secreted by the beta cells of the pancreas. Insulin II regulates glucose metabolism, promotes protein synthesis and inhibits lipolysis. It can be used as a research tool to study protein interactions, activators and ligands, receptor binding and ion channel activity. Insulin II can also be used to generate monoclonal antibodies against insulin II.<br>This product has the three code sequence: A-chain: Gly-Ile-Val-Asp-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn ; B-chain:Phe-Val-Lys-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Met-Ser, has the disulfide bonds: CysA6-CysA11, CysA7-CysB7, and CysA20-CysB19 and is available as a 50 µg vial.</p>

<p>Epidermal Growth Factor Receptor, Mouse Anti Human is a mouse monoclonal antibody that blocks the receptor for epidermal growth factor (EGF). It is used as an inhibitor of EGF to study the cell biology of EGF-dependent processes and for diagnosis of diseases such as cancer. Epidermal Growth Factor Receptor, Mouse Anti Human has shown specificity for human EGFR. This antibody can be used in immunohistochemistry and Western blotting procedures. The antibody recognizes the extracellular domain of EGFR, which is present on all cells that express this receptor.</p>

<p>This Thyroglobulin VIF Light Tryptic Peptide Standard is useful in protein identification and quantitation studies such as liquid chromatography-tandem mass spectrometry (LC-MS/MS). The use of tryptic peptides overcomes the challenges of quantifying serum thyroglobulin levels using immunoassays through removing the risk of interferences from Thyroglobulin antibodies. Thyroglobulin is a thyroid hormone production substrate and thus an important biomarker for differentiated thyroid cancer.</p>

<p>Peptide H-LSPSFADLFR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-NVNDVIAPAFVK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LLSATDTLDEAER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AYGRKKRRQRRR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-HGEGTFTSDVSSYLEEQAAK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Myelin Oligodendrocyte Glycoprotein Peptide (35-55) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-GCGGGYGRKKRRQRRR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-ILVDWLVEV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DAGTIAGLNVMR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SSLLDVLAAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LGFDC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-SLQAFQDYIR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide Boc-SC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VMAPWTLIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LESNNYNTYR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IGLDLPALNMQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TVRHPEW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-PVLDLFRELLNELLEALKQKLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-GFLSDLLK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IFFVNPAPPYLWPAHK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Thymosin, beta 10 (human, rat) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>KLA10 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-EANQSTLENFLER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-SGRGKQGGKAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-LLEVPEGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Neuromedin-U-23 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-SQNPVQPIGPQTPK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-RRRRRRRRRC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Cancer/testis antigen 1 (92-100) is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>[Leu3]-Oxytocin is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-ILIDWLVQV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Human Natriuretic peptides A (NPPA) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-FELLPTPPL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-CGKLFGTSGQK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-NQEQVSPLERCG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Beta-Amyloid (17-28) is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-STRQALRPRADGPVG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-DIDDLELTLAK-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-QNTESKSSE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Lipopolysaccharide (LPS) binding protein heavy tryptic peptide standard for use in proteomic studies. LPS are located on the outer membrane of gram-negative bacteria and are made up of a hydrophilic core polysaccharide, an O-antigen and a hydrophobic lipid A domain. As LPS is involved in interactions between the host and the pathogen it can be used as a biomarker giving an indication of infection.</p>

<p>Hi-5 is a recombinant, human protein that inhibits the high mobility group box 1 (HMGB1), an inflammatory mediator. HMGB1 is produced by activated macrophages and triggers inflammation reactions in response to tissue injury or infection. Hi-5 can be used as a pharmacological tool for the study of HMGB1-mediated inflammation and as a research tool for the discovery of new drugs that target HMGB1.<br>Hi-5 has been shown to inhibit the interaction between HMGB1 and its receptors, which may be due to its ability to bind to both ligands and receptors of HMGB1.</p>

<p>A Cholesterol Ester Transfer Protein (CETP) light tryptic peptide standard responsible for use in protein identification and quantitation studies. CETP is an enzyme which moves cholesterol esters from high density lipoproteins (HDL) to apolioprotein B-containing particles. This action lowers the amount of HDL which may increase the risk of the disease atherosclerosis.</p>

<p>Peptide H-TRSEL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The recombinant human cytidine monophosphate kinase 1 (CMPK) enzyme is a peptide with an N-terminal His tag. The enzyme is activated by ATP and phosphorylates the 3' carbon of cytidine monophosphate to form CMP. CMPK is also inhibited by a number of ligands, including adenosine, AMP, and guanosine. It has been shown that the binding of these ligands to CMPK affects ion channel activity in cells. This recombinant human CMPK enzyme is used in research as a tool for investigating protein interactions and pharmacological responses.<br>CAS Number: 223435-78-6</p>

<p>ATP Synthase Subunit O, Mitochondrial is a recombinant protein that belongs to the ATP synthase subunit family. It has been shown to be an activator of ion channels and receptor. The protein is also able to facilitate the interactions between proteins and ligands. ATP Synthase Subunit O, Mitochondrial has a molecular weight of approximately 44 kDa and an isoelectric point of 9.6. This product can be used as research tool for cell biology, pharmacology, and biochemistry studies.</p>

<p>Human IgG3 (hinge) heavy tryptic peptide standard for use in protein identification and quantitation studies. Human IgG3 is one of the four subclasses of IgG and it induces complement-mediated cellular lysis. Its hinge region is extended and is made up of 62 amino acids.</p>

<p>An apolipoprotein E C-term light tryptic peptide standard for use in protein identification and quantitation studies. As part of a fat-binding protein family, apolipoprotein E plays a role in the metabolism of fats in the body through interacting with the low density lipoprotein receptor, which is involved in the catabolism of triglyceride rich lipoproteins. Apolipoprotein E is also a major component in cholesterol metabolism and is a carrier of cholesterol in the brain. Additionally when forming a complex with C1q, apolipoprotein E is an inhibitor of the classical complement pathway. The N and C terminal regions of apolipoprotein are connected by a hinge region and the C-terminal region is a hydrophobic surface made up of three alpha helices and a low density lipoprotein receptor binding site.</p>

<p>TentaGel® Macrobead-NH2 Resin (Particle size: 140-170 µm) is a building block for peptide synthesis. It is a resin of crosslinked polystyrene macroparticles with an average particle size of 140-170 µm. TentaGel® Macrobead-NH2 Resin (Particle size: 140-170 µm) is used as a solid support in peptide synthesis. The resin is made up of crosslinked polystyrene macroparticles that are insoluble in water and organic solvents, making it particularly suitable for use as a solid support in peptide synthesis.</p>

<p>For Protein Identification and Quantitation</p>

<p>An Alpha-2-antiplasmin heavy tryptic peptide standard for protein identification and quantitation studies. Alpha-2-antiplasmin is a serine protease inhibitor of plasmin, an enzyme involved in fibrinolysis.</p>

<p>Please enquire for more information about Fmoc-His(MBom)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>T22 peptide, also known as [Tyr5,12,Lys7]-polyphemusin II peptide, is a short, positively charged peptide, analog of polyphemusin peptide which exerts a strong anti- HIV activity. Polyphemusins are known to inhibit the growth of gram-negative bacteria and some fungi such as Candida Albicans. T22 is a potent antagonist of CXCR4 (IC50 = 5.05 nM), a co-receptor used by HIV to penetrate cells.<br>It has been suggested that T22 exerts its effect against HIV-1 especially by blocking virus-cell fusion and that T22 might interact with HIV envelope protein (such as gp120 ) and T-cell surface protein. T22 antiviral activity has been shown on HIV-infected MT-4 cells with an IC50 of 0.008 µg/mL (2.6 nM). The cytotoxic concentration on HIV virus (CC50) of T22 is 54 µg/mL (17 mM).</p>

<p>Hepcidin is a peptide hormone that regulates iron absorption in the intestine. It is secreted by hepatocytes, the primary cells of the liver. Hepcidin-Murine Compete^TM ELISA Kit (1ea) is a competitive enzyme-linked immunosorbent assay (ELISA) kit for measuring hepcidin concentrations in mouse serum. This assay has been validated to measure hepcidin concentrations up to 1000 pg/mL with sensitivity as low as 1 pg/mL. The kit can be used to diagnose iron deficiency anemia and other diseases associated with hepcidin deficiency.</p>

<p>Ala-Arg-Gly-Ile-Lys-Gly-Ile-Arg-Gly-Phe-Ser-Gly• 3AcOH• 5H2O is a peptide that is the substrate for lysine hydroxylase. Lysine hydroxylase catalyzes the conversion of lysine to 2,3 diaminopropionic acid (DAPA) and hydrogen peroxide. The reaction proceeds in two steps: first, the enzyme converts L -lysine to L -3,4 diaminobutyric acid (DABA), then it reacts with oxygen to form DAPA.</p>

<p>For Protein Identification and Quantitation</p>

<p>Please enquire for more information about Pirin Human Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>An Alpha-2-Macroglobulin light tryptic peptide standard for protein identification and quantitation studies. Alpha-2-Macroglobulin is a broad spectrum protease inhibitor which also plays roles in cell migration and in the binding of growth factors and cytokines.</p>

<p>Peptide H-NVEDLSGGELQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>An Apolipoprotein B light tryptic peptide standard for use in protein identification and quantitation studies. Apolipoprotein B is responsibly for carrying lipids such as low density lipoprotein (LDL), chylomicrons, intermediate-density lipoprotein, very low-density lipoprotein and lipoprotein (a).</p>

<p>Jingzhaotoxin III is a small peptide that has been expressed in Drosophila melanogaster and has been shown to have an inhibitory effect on brain natriuretic peptide (BNP). Jingzhaotoxin III decreases the amplitude of BNP-induced camp levels, and this decrease can be reversed by removing extracellular calcium. Jingzhaotoxin III also has a voltage-gated sodium channel blocking effect, which can be inhibited by adding extracellular calcium. Jingzhaotoxin III interacts with calyces and blocks their activation. This inhibition of calyx activation is reversible when extracellular calcium is removed.</p>

<p>Research Peptide</p>

<p>PP27894</p>

<p>Research Peptide</p>

<p>Research peptide</p>

<p>Amyloid Beta-Protein (Human, 1-40) Antiserum is an antibody, which is a protein that recognizes and binds to a specific antigen. The Amyloid Beta-Protein (Human, 1-40) Antiserum can bind to amyloid beta protein in the brain and trigger immune system cells to clear it from the body. This antibody can also be used as a research tool for studying the structure of amyloid beta protein and how it affects human cells.</p>

<p>TGF-β is a cytokine with two forms, TGF-β1 and TGF-β2. The tgf-beta protein is a molecule that controls cell growth, differentiation and apoptosis. It can be found in the desiccated state, which must be reconstituted before use. Reconstitution of the protein requires acetonitrile and trifluoroacetic acid. Cytokines are molecules that regulate cell behavior by acting on other cells. Chromatographic techniques are used to separate these molecules by size and charge, while growth factors are molecules that promote cell growth and differentiation. The experimentally determined molecular mass of TGF-β1 is 25 kDa.END&gt;</p>

<p>NHS-m-dPEG® (MW = 685) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-m-dPEG® (MW = 685) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Hepatitis E virus (HEV) is a virus that infects the liver and causes hepatitis. Recombinant HEV ORF2 protein was produced by recombinant techniques in Escherichia coli. The recombinant HEV ORF2 protein has been shown to be immunogenic in mice, rabbits, and humans. Immunodominant epitopes were found at amino acid positions 448-456 and 468-480.</p>

<p>Peptide H-TSALLAGTITSGWTF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Vimentin is a protein that is expressed in the cytoplasm of cells. It is found in fibroblasts, osteoblasts, and endothelial cells. Vimentin is a member of the intermediate filament family. This antibody reacts with vimentin as well as other intermediate filaments such as desmin and keratin. The FITC tag allows for visualization of the antibody under fluorescent microscopy. Reconstitute with PBS before use.</p>

<p>Cyclosporin-A is a cyclic peptide that inhibits mitochondrial functions and has been used to prevent organ rejection in transplant patients. It binds to the cyclase enzyme and prevents the formation of cyclic adenosine monophosphate (cAMP) from ATP, which is required for cell growth. Cyclosporin-A also inhibits the production of proteins by preventing transcription, replication, and translation. This drug can cause neurotoxicity when administered at high doses or over a long period of time. In vitro assays have shown that cyclosporin-A has cytotoxic effects on platinum-resistant ovarian cancer cells. It also has an effect on microdialysis probes, which may be due to its ability to inhibit neurotransmitter release from neurons. Cyclosporin-A has been shown to inhibit the production of protein in vivo, as evidenced by a decrease in weight gain in rats treated with this drug for one week.</p>

<p>Anti C-Peptide II (Rat) Serum is a high-purity peptide that can be used as a research tool to study the pharmacology of peptides and their interactions with receptors. It can also be used as an inhibitor in cell biology experiments.</p>

<p>Insulin-like growth factor 1 (IGF1) is a cytokine that belongs to the family of growth factors. IGF1 is a peptide hormone that mediates its effects by binding to cell surface receptors and activating signal transduction pathways inside cells. IGF1 stimulates glucose uptake, protein synthesis, and lipolysis in muscle and adipose tissue. The A67T variant of IGF1 has been shown to have increased activity in stimulating insulin-like signaling pathways and mediating the effects of IGF1 on glucose metabolism. This variant is associated with increased risk for type 2 diabetes mellitus (DM).</p>

<p>IP-10 is a chemokine that is expressed in the human immune system. IP-10 can be released from cells such as macrophages, neutrophils, and mast cells in response to inflammatory stimuli. This protein is important for the recruitment of lymphocytes and monocytes to sites of infection or injury. IP-10 also has antitumor activity, which may be due to its ability to induce apoptosis in tumor cells.</p>

<p>The anti G-protein: Galpha i3 (105-127) is a recombinant human serum protein. This antibody was raised against the peptide sequence of human Galpha i3 (105-127). It has been purified by Protein A and gel exclusion chromatography. The peptide sequence of this antibody is as follows: YGRKKRRQRRRPPPPPPRRRQRRKSSSSSEEEEDEESDS.</p>

<p>SPDP-dPEG®8-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. SPDP-dPEG®8-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>IL-11 is a cytokine that is synthesized by cells of the immune system and functions as an autocrine growth factor for cells of the myeloid lineage. IL-11's receptor is a protein that binds to the IL-11 peptide and this binding activates intracellular signaling pathways.</p>

<p>RNA Binding Motif Protein 3 (RBMY3) is a high-quality research peptide that is commonly used in scientific studies. It is a recombinant protein derived from Escherichia Coli. RBMY3 plays a crucial role in RNA metabolism and regulation, specifically in the binding and processing of RNA molecules. This protein is highly purified and has been extensively tested for its quality and functionality. Researchers rely on RBMY3 to study various cellular processes, including gene expression, mRNA splicing, and post-transcriptional modifications. With its exceptional purity and reliability, RBMY3 is an essential tool for any laboratory conducting cutting-edge research in the field of RNA biology.</p>

<p>Neurotensin is a neuropeptide that is involved in the regulation of a variety of physiological functions, including neurotransmission, cardiovascular function, and appetite. It is composed of 13 amino acids and is primarily produced in the gastrointestinal tract and the central nervous system.<br>Neurotensin acts as a neurotransmitter and neuromodulator in the brain, where it is synthesized by neurons in several regions, including the hypothalamus, amygdala, and nucleus accumbens. In addition to its role in neurotransmission, neurotensin has been shown to be involved in the regulation of food intake and energy metabolism. It is thought to promote satiety and reduce food intake by interacting with the hypothalamus and other brain regions involved in appetite regulation.<br>Neurotensin has also been studied for its potential therapeutic applications as it has been shown to be associated with the pathophysiology of conditions such as Parkinson's disease, pain, schizophrenia, cancer and inflammatory bowel disease.</p>

<p>Urocortin 2 (Mouse)-EIA Kit is a specialty product that can be used to detect the presence of Urocortin 2 in mouse serum. It is an antibody-based sandwich ELISA kit that has been optimized for use in mouse sera and other biological fluids. The kit includes all necessary reagents, including antibodies, standards, and conjugates, to perform an assay. The assay is performed by adding the sample to the plate followed by the detection antibody and a conjugate. After incubation, unbound materials are washed away and the plate is developed with Tetramethylbenzidine (TMB) substrate. A stop solution turns TMB into a blue color that can be measured at 450 nm with a spectrophotometer. The intensity of color corresponds to the concentration of Urocortin 2 in the sample.br&gt;br&gt;<br>The Urocortin 2 (Mouse)-EIA Kit is designed for research purposes only and not for diagnostic</p>

<p>[D-Ala2,Met5]-Enkephalin is an inhibitory neurotransmitter that binds to receptors in the brain and spinal cord. It affects physiological functions such as locomotion, pain sensation, and blood pressure. Enkephalins are analogs of the natural neurotransmitter enkephalin that are synthesized by enzymatic cleavage of the latter from a larger precursor molecule called proenkephalin. [D-Ala2,Met5]-Enkephalin has been shown to be an effective antinociceptive agent when administered intraperitoneally or intravenously in rats. It also acts as a pressor agent and produces dextran sulfate-induced nociception in mice. The pharmacological properties of enkephalins have been shown using various analytical methods including acid analysis.</p>

<p>Insulin is a peptide hormone that regulates glucose levels in the blood. It is produced by beta cells in the pancreas and released when blood sugar levels rise. Insulin lowers blood sugar levels, but it also has other functions, such as protein synthesis and cell growth. Insulin stimulates receptors on cells to take up glucose from the bloodstream. Inhibitors of insulin are used for type 1 diabetes mellitus treatment and research purposes. Insulin can be used to study ion channels, antibody production, and receptor binding.</p>

<p>FRETS-25Met (1 umol) (1umol) is a peptide that binds to the beta2-adrenergic receptor. It is a high purity, research tool and can be used for binding studies as well as for inhibition of the receptor. FRETS-25Met (1 umol) (1umol) has been shown to bind to the beta2-adrenergic receptor with an affinity of 5 nM and an IC50 of 1.6 uM. This peptide has also been shown to act as a potent agonist in stimulating cAMP production in CHO cells expressing the beta2-adrenergic receptor.</p>

<p>MAL-dPEG®12-t-boc-Hydrazide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®12-t-boc-Hydrazide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Oxytocin is a hormone and neurotransmitter that is produced in the hypothalamus. It is released by the pituitary gland during labor to help with uterine contractions, and it stimulates milk production in the mammary glands. Oxytocin may be used to stimulate lactation or to assist in childbirth. The molecular mass of oxytocin is approximately 3,500 Da, which can be determined using chromatography with a retention time of 8-10 minutes and a peak at 3.5 minutes on reverse phase high performance liquid chromatography (RP-Hplc). Oxytocin has been synthesized chemically and freeze dried for use in research settings. Reconstitute with sterile water for injections before use. Oxytocin may also be used as an additive in food products as a flavor enhancer or preservative.</p>

<p>TentaGel B resins represent a line of bifunctional resins that are useful for orthogonal synthesis. TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 90 µm; capacity: 02-03 meq/g<br>Inside: NH2 Outside: Boc</p>

<p>The most potent microbicide of the mouse Paneth cell α-defensins and is degraded by MMP-7. This product has disulfide bonds between Cys4-Cys30, Cys15-Cys37, and Cys19-Cys39, is available in the Hydrochloride salt form and as a 0.1mg vial.</p>

<p>An aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition.  The amine terminus of the molecule reacts with carboxylic acids and their active esters to form stable amide bonds. Insoluble in water, DBCO-amine is slightly soluble to sparingly soluble in most organic solvents.</p>

<p>TentaGel is a water-soluble polymer that can be used as a building block for various applications including drug delivery, food and beverage, cosmetics, and electronics. It consists of two main components: polyethylene glycol (PEG) and polypropylene glycol (PPG). TentaGel is soluble in water and has an average molecular weight of about 10,000 Da. The PEG-based component allows the polymer to be easily processed into particles or fibers by sonication or extrusion. TentaGel M RAM is a modified version of the original TentaGel. It contains methacrylic acid groups that have been grafted onto the PEG backbone to provide additional functionality such as reactive surfaces for conjugation with proteins or other molecules.</p>

<p>Anti Insulin, humanSerum is a Research Tool used in the study of protein interactions. It is an antibody that binds to insulin and can be used as a research tool to identify other proteins with which insulin interacts. This product has been purified and is at least 98% pure.</p>

<p>4-Formyl-Benzamido-dPEG®12-EDA-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. 4-Formyl-Benzamido-dPEG®12-EDA-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Pro-Hyp-Gly is a polypeptide that inhibits collagenase, an enzyme that breaks down collagen. Collagenase is an enzyme that breaks down the protein collagen, which forms the connective tissue in humans and other animals. Pro-Hyp-Gly has been found to be a potent inhibitor of collagenase, and can be used for treatment of inflammatory diseases such as arthritis or skin lesions. Pro-Hyp-Gly also inhibits enzymes called proteases, which break down proteins outside of cells. Proteases are important in the breakdown of food particles in the stomach.</p>

<p>Apo B-1 is a major component of the lipoprotein particle. The APOB MS Calibrator provides a high quality, stable preparation of Apo B-1 for use as an internal standard for mass spectrometry analysis. The calibrator also contains a tryptic peptide that can be used for identification and quantification of this protein in proteomics experiments.</p>

<p>IGF-1 V44M is a recombinant protein that is an activator of the insulin receptor. It has been developed as a research tool to study the function of the insulin receptor and is used in pharmacological and cell biology studies. IGF-1 V44M is a single amino acid substitution of Valine at position 44, which replaces Methionine. The recombinant protein has a molecular weight of 10 kDa, and its purity is &gt;90%. IGF-1 V44M can be used to inhibit the activity of the insulin receptor by binding to it with high affinity.</p>

<p>m-dPEG®12-Amido-dPEG®12-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Amido-dPEG®12-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>FRETS-25Phe (1umol) (1umol) is a synthetic amino acid that is used as a research tool. It activates the Ligand and Receptor, which are proteins that bind to other proteins. FRETS-25Phe (1 umol) (1umol) binds to the Ion channels, which are protein structures that regulate the flow of ions across cell membranes. The activity of FRETS-25Phe (1 umol) (1umol) on Ion channels has been shown using an antibody, which is a type of protein used in immunology to identify, detect and measure antigens. FRETS-25Phe (1 umol) (1umol) also interacts with Cell Biology and Peptides, which are types of proteins involved in cell growth or division.</p>

<p>Human Serum Albumin is a stable protein that binds to fatty acids and helps transport them in the circulatory system. It can also bind to other molecules, such as drugs, and help with the transport of these molecules in the bloodstream. The protein is composed of amino acids, which are linked together by peptide bonds. The human serum albumin molecule has four subunits that are connected by disulfide bonds. These subunits are called alpha (α), beta (β), gamma (γ), and delta (δ). Human serum albumin contains many hydrophobic amino acids, which make it soluble in lipids and water. This protein is an important part of energy metabolism because it accepts electrons from fatty acid oxidation and transfers them to electron acceptors such as oxygen or NADPH.</p>

<p>Azido-PEG3-DYKDDDDK is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>Amino-dPEG®4-(m-dPEG®24)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®4-(m-dPEG®24)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Phth-dPEG®12-Tris (-TFP Ester)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Phth-dPEG®12-Tris (-TFP Ester)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>DBCO-dPEG®24-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DBCO-dPEG®24-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Beta-Defensin-1 (BD-1) is an antimicrobial peptide that is produced by various cells and tissues in mice, including epithelial cells in the skin, lungs, and intestines. BD-1 is a member of the beta-defensin family, which are small cationic peptides that play a role in innate immunity by protecting against microbial pathogens, including bacteria, fungi, and viruses.<br>In mice, BD-1 is constitutively expressed, meaning that it is produced at a relatively constant level in healthy animals. Its expression can be induced by various stimuli, including bacterial and viral infections, cytokines, and inflammatory mediators.<br>BD-1 is known to have broad-spectrum antimicrobial activity against a variety of pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. It achieves its antimicrobial activity by disrupting the cell membranes of the pathogens, leading to cell lysis and death.<br>In addition to its antimicrobial activity, BD-1 has been found to have other functions in mice, including promoting wound healing, regulating inflammation, and modulating the immune response.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>