Enyzmmodulatoren

Zoledronic acid is a drug that is used for the treatment of malignancy associated with …

Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 …

Natural anti-cancer agent; inhibitor of histone deacetylases

Bortezomib is a selective and reversible inhibitor of the multicatalytic 26S proteasome. The inhibition of …

Indirubin is a chemical compound that belongs to the indole family. It has been studied …

Inhibitor of GSK3 kinase; activator of Wnt signalling

Inhibitor of p38 MAPK kinase

Mitochondrial division inhibitor (mdivi-1) inhibits dynamin related protein-1 (drp1)-dependent mitochondrial fission. It is a therapeutic …

Inhibitor of sodium/potassium ATP-ase; anti-arrhythmic

Sumoylation inhibitor; reported to inhibit histone acetylation transferase

Gemcitabine is as a synthetic pyrimidine nucleoside prodrug. The hydrogen atoms on the 2' carbon …

Nicotinamide phosphoribosyl transferase (NAMPT) competitive inhibitor with IC50 = 3.1 nM. A major consequence of …

Imatinib is a tyrosine kinase inhibitor that is used in the treatment of various leukemias …

Inhibitor of histone deacetylase 3 (HDAC3) with IC50 in nanomolar range. BRD 9908 was shown …

Rapamycin is a macrolide antibiotic that has been studied as a potential anticancer agent. It …

Selective, potent, competitive and reversible inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) with IC50 …

Irreversible blocker of three members of the ErbB family (ErbB1, ErbB2/HER2, and ErbB4) with IC50 …

Inhibits Mer receptor tyrosine kinase (IC50 = 4.3 nM). Selective over Axl (84-fold) and Tyro3 …

Selective inhibitor of the mutated RET variant RETV804M, which is the anticipated drug-resistant RET mutant …

Inhibitor of VEGF receptor tyrosine kinases and non-receptor tyrosine kinases

Cerivastatin is a drug that belongs to the class of drugs called statins. This drug …

Protein kinase B (also known as RAC-alpha serine/threonine-protein kinase: Atk) is a serum and glucocorticoid-regulated …

The sequence of this peptide has been derived from a highly conserved region of the …

Cyclin-dependent kinases (CDKs) are a family of kinases that regulate the cell cycle and gene …

Ile-Pro-Pro (IPP) has the ability to inhibit angiotensin-converting enzyme and stimulate the production of nitric …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is negative regulator of hepatic low-density lipoprotein (LDL) receptors …

Abltide represents the optimal substrate peptide of Abl (or c-Abl), a non-receptor tyrosine kinase (NRTK) …

RNase A (8-13) is a site-specific endoribonuclease that cleaves RNA and is used for the …

eV1-2 is a selective εPKC inhibitor peptide which interferes with protein-protein interactions between the ϵPKC …

Acid α-glucosidase (83-99) (human) is derived from the exogenous enzyme which degrades glycogen, maltose and …

This peptide is phosphorylated by Janus kinase 2 (JAK2) and is an ideal substrate for …

During extraction of lecithin from egg yolk, peptide by-products can be isolated and purified by …

A15 also known as alpha2-Antiplasmin is a serine/protease inhibitor which inactivates plasmin in the blood. …

DARKtide is a substrate peptide for death-associated protein kinase (DAPK) for use in kinases assays. …

Amino acids 651-660 of Poly(ADP-ribose) polymerase 1 (PARP1). PARP1 is a nuclear DNA repair enzyme …

Axltide-is a substrate peptide for use in kinase assays and is based on the mouse …

Substrate for proline-rich tyrosine kinase 2 (Pyk2)- can be used for substrate phosphorylation assays. Pyk2 …

ERKtide Substrate Peptide.

During extraction of lecithin from egg yolk, peptide by-products can be isolated and purified by …

During extraction of lecithin from egg yolk, peptide by-products can be isolated and purified by …

The peptide IRW, characterised from egg protein, exhibits inhibitory properties against the angiotensin converting enzyme …

Peptide derived from the endothelial nitric oxide synthase which synthesises nitric oxide in order to …

Human epidermal growth factor receptor 2 (HER-2)/epidermal growth factor receptor-2 (ErbB-2), is a key receptor …

This peptide is phosphorylated by Janus kinase 1 (JAK1) and is an ideal substrate for …

Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) and its negative regulator Kelch-Like ECH-Associated Protein 1 …

A glycogen synthase kinase 3β- (GSK3β-) / crosstide fragment representing the phosphorylation site on GSK3β-. …

Amino acids 487-496 of Poly(ADP-ribose) polymerase 1 (PARP1). PARP1 is a nuclear DNA repair enzyme …

LRRKtide (also called moesin) is a peptide substrate for leucine-rich repeat kinase 2 (LRRK2). The …

A protein kinase G selective substrate for use in kinases assays, with a preference for …

Substrate peptide for protein tyrosine phosphatase 1B (PTP1B)- an ubiquitously expressed non-receptor tyrosine phosphatase. PTP1B …

Autocamtide-2-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor.CAMK represents a class of …

Amino acids 359-409 of human glycogen synthase kinase 3 β (GSKβ), a multifunctional serine/threonine kinase …

Amino acids 487-496 of Poly(ADP-ribose) polymerase 1 (PARP1). PARP1 is a nuclear DNA repair enzyme …

Cell permeable peptide which is able to activate phosphoinositide 3- kinase, for which it binds …

LRRKtide (also called moesin) is a peptide substrate for leucine-rich repeat kinase 2 (LRRK2). The …

AMARA peptide is a fragment containing the phosphorylation site for AMP activated protein kinase (AMPK) …

MGMT, known as O6-methylguanine-DNA methyltransferase, is a DNA repair enzyme that plays an important role …

This peptide is phosphorylated by Janus kinase 1 (JAK1) and is an ideal substrate for …

During extraction of lecithin from egg yolk, peptide by-products can be isolated and purified by …

Autocamtide-3-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor. AC3-I is derived from …

HMG-CoA reductase inhibitor; anti-hypercholesterolemia agent

Orlistat is a drug that has been approved for the treatment of obesity. It inhibits …

Etoricoxib is a cyclooxygenase-2 (COX-2) inhibitor, which is a type of nonsteroidal anti-inflammatory drug (NSAID). …

Cyclosporin A (CsA) is a cyclic undecapeptide that is extracted from the fungus Tolypocladium inflatum. …

novel tricyclic indole; promising new treatment for a variety of diseases

Pentoxifylline is a methylxanthine derivative that is used to treat intermittent claudication that is caused …

Inhibitor of S-adenosylhomocysteine hydrolase that disrupts histone methylation by EZH2. Anti-proliferative in some breast cancer …

Ozagrel is an antiplatelet agent that is also a thromboxane A2 synthetase inhibitor. It is …

Doxorubicin hydrochloride is an inhibitor of topoisomerase II with anti-neoplastic activity and belongs to the …

Bruton's tyrosine kinase antagonist; reduces Fcγ receptor signaling

γ-secretase inhibitor; inhibits notch signaling

Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is …

Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. …

Potent and specific inhibitor of the tyrosine protein kinase Mer precursor (MERTK) with 38-fold selectivity …

Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia …

Inhibits JAK1 and JAK2 kinases

Toceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be …

Nabumetone is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and …

Sorafenib is a drug that belongs to the class of multikinase inhibitors. It inhibits a …

Pan-class I phosphatidylinositide 3-kinase (PI3K) inhibitor (IC50 = 3, 33, 3 and 75 nM at …

Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric …

Acetylcholinesterase inhibitor; therapy for Alzheimer's disease