Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 1431 productos de "Angiogénesis"

Pureza (%)

100

productos por página.

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Momelotinib HCl
CAS:
- 1380317-28-1
Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.
Fórmula:C₂₃H₂₄Cl₂N₆O₂
Forma y color:Solid
Peso molecular:487.38
Ref: TM-T70823
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EHop-016
CAS:
- 1380432-32-5
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
Fórmula:C₂₅H₃₀N₆O
Pureza:98.99% - >99.99%
Forma y color:Solid
Peso molecular:430.55
Ref: TM-T2427
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SB-431542
CAS:
- 301836-41-9
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.
Fórmula:C₂₂H₁₆N₄O₃
Pureza:99.035% - >99.99%
Forma y color:Solid
Peso molecular:384.39
Ref: TM-T1726
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Adaphostin
CAS:
- 241127-58-2
Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.
Fórmula:C₂₄H₂₇NO₄
Pureza:98.29%
Forma y color:Solid
Peso molecular:393.48
Ref: TM-T22553
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(Z)-SU4312
CAS:
- 90828-16-3
(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Fórmula:C₁₇H₁₆N₂O
Pureza:99.17%
Forma y color:Solid
Peso molecular:264.32
Ref: TM-T5676
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GDC-0214
CAS:
- 1831144-46-7
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
Fórmula:C₂₈H₂₈ClF₂N₉O₃
Pureza:99.75%
Forma y color:Solid
Peso molecular:612.03
Ref: TM-T9826
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E-4031 dihydrochloride
CAS:
- 113559-13-0
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
Fórmula:C₂₁H₂₉Cl₂N₃O₃S
Pureza:99.31% - 99.87%
Forma y color:Solid
Peso molecular:474.44
Ref: TM-T7198
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SKLB4771
CAS:
- 1370256-78-2
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
Fórmula:C₂₅H₂₇N₇O₃S₂
Pureza:98% - >99.99%
Forma y color:Solid
Peso molecular:537.66
Ref: TM-T2051
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WS6
CAS:
- 1421227-53-3
WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
Fórmula:C₂₉H₃₁F₃N₆O₃
Pureza:97.65% - 99.95%
Forma y color:Solid
Peso molecular:568.59
Ref: TM-T2106
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CZC-8004
CAS:
- 916603-07-1
CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Fórmula:C₁₇H₁₆FN₅
Pureza:99.29%
Forma y color:Solid
Peso molecular:309.34
Ref: TM-T7186
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NRC-2694 hydrochloride
CAS:
- 1172626-99-1
NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.
Fórmula:C₂₄H₂₇ClN₄O₃
Forma y color:Solid
Peso molecular:454.95
Ref: TM-T71332
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NS309
CAS:
- 18711-16-5
NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.
Fórmula:C₈H₄Cl₂N₂O₂
Pureza:97.55%
Forma y color:Solid
Peso molecular:231.04
Ref: TM-T4612
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Zorifertinib
CAS:
- 1626387-80-1
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.
Fórmula:C₂₂H₂₃ClFN₅O₃
Pureza:98.20% - 99.36%
Forma y color:White To Off-White Solid
Peso molecular:459.9
Ref: TM-T3659
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(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.
Fórmula:C₂₉H₃₂N₄O₈
Forma y color:Solid
Peso molecular:564.59
Ref: TM-T63998
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Afatinib
CAS:
- 850140-72-6
Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.
Fórmula:C₂₄H₂₅ClFN₅O₃
Pureza:98.56% - 99.9%
Forma y color:Off-White Solid
Peso molecular:485.94
Ref: TM-T21312
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NVP-BSK805 trihydrochloride
CAS:
- 2320258-95-3
NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.
Fórmula:C₂₇H₃₁Cl₃F₂N₆O
Forma y color:Solid
Peso molecular:599.93
Ref: TM-T39858
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CGP77675 hydrate
CGP77675 hydrate: Oral Src family kinase inhibitor with IC50s of 5-20/40 nM (Src auto/phosphorylation) and has anticancer properties.
Forma y color:Solid
Ref: TM-T30855L
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Trastuzumab
CAS:
- 180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.
Pureza:98% - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%
Forma y color:Liquid
Peso molecular:Approximately 145.53 kDa
Ref: TM-T9912
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AG1557
CAS:
- 189290-58-2
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Fórmula:C₁₆H₁₄IN₃O₂
Pureza:98.61% - 99.23%
Forma y color:Solid
Peso molecular:407.21
Ref: TM-T2034
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Canertinib
CAS:
- 267243-28-7
Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.
Fórmula:C₂₄H₂₅ClFN₅O₃
Pureza:98% - >99.99%
Forma y color:White Or Similar To White Crystalline Powder
Peso molecular:485.94
Ref: TM-T6136