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Apoptosis

Apoptosis

Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.

Subcategorías de "Apoptosis"

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Se han encontrado 5600 productos de "Apoptosis"

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  • Thalidomide-O-amido-PEG2-C2-NH2 TFA

    CAS:
    <p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>
    Fórmula:C23H27F3N4O10
    Pureza:95.74% - 99%
    Forma y color:Solid
    Peso molecular:576.48
  • PD173955

    CAS:
    <p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>
    Fórmula:C21H16Cl2N4OS
    Pureza:98.52% - 98.99%
    Forma y color:Solid
    Peso molecular:443.35
  • Solasodine

    CAS:
    <p>Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.</p>
    Fórmula:C27H43NO2
    Pureza:99.64% - 99.94%
    Forma y color:Solid
    Peso molecular:413.64
  • Xevinapant

    CAS:
    <p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>
    Fórmula:C32H43N5O4
    Pureza:98% - 99.94%
    Forma y color:Solid
    Peso molecular:561.71
  • TAS6417

    CAS:
    <p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>
    Fórmula:C23H20N6O
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:396.44
  • SBE13 Hydrochloride

    CAS:
    <p>SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.</p>
    Fórmula:C24H28Cl2N2O4
    Pureza:99.00% - ≥95%
    Forma y color:Solid
    Peso molecular:479.4
  • Ispinesib

    CAS:
    <p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>
    Fórmula:C30H33ClN4O2
    Pureza:98% - 99.09%
    Forma y color:Solid
    Peso molecular:517.06
  • 4E1rcat

    CAS:
    <p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>
    Fórmula:C28H18N2O6
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:478.45
  • IMT1

    CAS:
    <p>IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.</p>
    Fórmula:C21H21NO4
    Pureza:98.07% - 98.14%
    Forma y color:Solid
    Peso molecular:351.4
  • Scopoletin

    CAS:
    <p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>
    Fórmula:C10H8O4
    Pureza:97.06% - 99.88%
    Forma y color:Yellow To Beige Crystalline Powder
    Peso molecular:192.17
  • RGX-202

    CAS:
    <p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>
    Fórmula:C4H9N3O2
    Pureza:99.67% - 99.8%
    Forma y color:Solid
    Peso molecular:131.13
  • Cystamine dihydrochloride

    CAS:
    <p>Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.</p>
    Fórmula:C4H14Cl2N2S2
    Pureza:98.91% - 99.81%
    Forma y color:White Powder
    Peso molecular:225.19
  • Hexamethylene bisacetamide

    CAS:
    <p>Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.</p>
    Fórmula:C10H20N2O2
    Pureza:99.94%
    Forma y color:White Flakes
    Peso molecular:200.28
  • MS7972

    CAS:
    <p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>
    Fórmula:C14H13NO2
    Pureza:99.78%
    Forma y color:Solid
    Peso molecular:227.26
  • 4-MMPB

    CAS:
    <p>15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.</p>
    Fórmula:C16H19N5S
    Pureza:97.18%
    Forma y color:Solid
    Peso molecular:313.42
  • Macitentan

    CAS:
    <p>Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).</p>
    Fórmula:C19H20Br2N6O4S
    Pureza:98% - >99.99%
    Forma y color:Solid
    Peso molecular:588.27
  • Bay 11-7085

    CAS:
    <p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>
    Fórmula:C13H15NO2S
    Pureza:99.76% - 99.94%
    Forma y color:White Solid
    Peso molecular:249.33
  • LYN-1604 dihydrochloride

    CAS:
    <p>LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
    Fórmula:C33H45Cl4N3O2
    Pureza:98.95% - 99.92%
    Forma y color:Solid
    Peso molecular:657.54
  • Resatorvid

    CAS:
    <p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>
    Fórmula:C15H17ClFNO4S
    Pureza:99.31% - >99.99%
    Forma y color:Solid
    Peso molecular:361.82
  • GDC-0623

    CAS:
    <p>GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.</p>
    Fórmula:C16H14FIN4O3
    Pureza:98.95% - 99.02%
    Forma y color:Solid
    Peso molecular:456.21
  • UNC1215

    CAS:
    <p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>
    Fórmula:C32H43N5O2
    Pureza:98% - 99.04%
    Forma y color:Solid
    Peso molecular:529.72
  • SNS-032

    CAS:
    <p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>
    Fórmula:C17H24N4O2S2
    Pureza:98.27% - 99.91%
    Forma y color:Solid
    Peso molecular:380.53
  • AES-350

    CAS:
    <p>AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.</p>
    Fórmula:C18H20N2O3
    Pureza:98.82%
    Forma y color:Solid
    Peso molecular:312.36
  • N-Formyl-Met-Leu-Phe

    CAS:
    <p>N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).</p>
    Fórmula:C21H31N3O5S
    Pureza:98.69% - ≥95%
    Forma y color:Solid
    Peso molecular:437.55
  • Euphorbia Factor L2

    CAS:
    <p>Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.</p>
    Fórmula:C38H42O9
    Pureza:99.53% - 99.96%
    Forma y color:Solid
    Peso molecular:642.73
  • Rotundic acid

    CAS:
    <p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>
    Fórmula:C30H48O5
    Pureza:96.91% - 99.97%
    Forma y color:Solid
    Peso molecular:488.7
  • Olsalazine

    CAS:
    <p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>
    Fórmula:C14H10N2O6
    Pureza:99.31%
    Forma y color:Solid
    Peso molecular:302.24
  • YK-4-279

    CAS:
    <p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>
    Fórmula:C17H13Cl2NO4
    Pureza:99.80% - ≥95%
    Forma y color:Solid
    Peso molecular:366.2
  • Cinobufagin

    CAS:
    <p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>
    Fórmula:C26H34O6
    Pureza:97.77% - 99.97%
    Forma y color:Solid
    Peso molecular:442.54
  • Necrostatin-1

    CAS:
    <p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>
    Fórmula:C13H13N3OS
    Pureza:99.25% - >99.99%
    Forma y color:Solid
    Peso molecular:259.33
  • FLLL32

    CAS:
    <p>FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of &lt;5 μM).</p>
    Fórmula:C28H32O6
    Pureza:97% - 97.90%
    Forma y color:Solid
    Peso molecular:464.55
  • Pralatrexate

    CAS:
    <p>Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate</p>
    Fórmula:C23H23N7O5
    Pureza:94.32% - 99.59%
    Forma y color:Solid
    Peso molecular:477.47
  • PD-1/PD-L1-IN-10

    CAS:
    <p>PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor activity.Cost-effective and quality-assured.</p>
    Fórmula:C33H31N3O7
    Pureza:99.63%
    Forma y color:Solid
    Peso molecular:581.62
  • Neobavaisoflavone

    CAS:
    <p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>
    Fórmula:C20H18O4
    Pureza:99.31% - 99.87%
    Forma y color:Solid
    Peso molecular:322.35
  • L-Glutamic acid monosodium salt

    CAS:
    <p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>
    Fórmula:C5H8NO4·Na
    Pureza:99.93%
    Forma y color:White Solid Crystalline
    Peso molecular:169.11
  • Bullatine A

    CAS:
    <p>1.</p>
    Fórmula:C22H33NO2
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:343.51
  • HS-1793

    CAS:
    <p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>
    Fórmula:C16H12O3
    Pureza:98.16% - 99.82%
    Forma y color:Solid
    Peso molecular:252.26
  • Obatoclax Mesylate

    CAS:
    Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and
    Fórmula:C20H19N3O·CH4O3S
    Pureza:99.58% - 99.88%
    Forma y color:Solid
    Peso molecular:413.49
  • Danshensu

    CAS:
    <p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>
    Fórmula:C9H10O5
    Pureza:98.4% - 99.74%
    Forma y color:Solid
    Peso molecular:198.17
  • CHR-6494 TFA

    CAS:
    <p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>
    Fórmula:C18H17F3N6O2
    Pureza:99.50%
    Forma y color:Solid
    Peso molecular:406.36
  • MPTP hydrochloride

    CAS:
    <p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>
    Fórmula:C12H16ClN
    Pureza:96.35% - >99.99%
    Forma y color:Solid
    Peso molecular:209.72
  • Ketorolac

    CAS:
    <p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>
    Fórmula:C15H13NO3
    Pureza:99.68%
    Forma y color:White Crystalline Or White Powder
    Peso molecular:255.27
  • MDK83190

    CAS:
    <p>MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .</p>
    Fórmula:C15H9Cl2NO2
    Pureza:97.40% - 98%
    Forma y color:Orange Solid
    Peso molecular:306.14
  • Choline

    CAS:
    <p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>
    Fórmula:C5H15NO2
    Pureza:99.97% - ≥98%
    Forma y color:Liquid
    Peso molecular:121.18
  • Niraparib hydrochloride

    CAS:
    <p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>
    Fórmula:C19H21ClN4O
    Pureza:99.26%
    Forma y color:Solid
    Peso molecular:356.85
  • BG45

    CAS:
    <p>BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and &gt;20 μM for HDAC3/1/2/6 in cell-free assays, respectively.</p>
    Fórmula:C11H10N4O
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:214.22
  • (S)-crizotinib

    CAS:
    <p>(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>
    Fórmula:C21H22Cl2FN5O
    Pureza:98.52% - 99.47%
    Forma y color:Solid
    Peso molecular:450.34
  • 7,8-Dihydroxyflavone

    CAS:
    <p>7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula tree leaves.</p>
    Fórmula:C15H10O4
    Pureza:98.48% - 99.81%
    Forma y color:Solid
    Peso molecular:254.24
  • RHPS4

    CAS:
    <p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>
    Fórmula:C22H17F2N2·CH3O4S
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:458.48
  • Tenilsetam

    CAS:
    <p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>
    Fórmula:C8H10N2OS
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:182.24
  • AZD1208

    CAS:
    <p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>
    Fórmula:C21H21N3O2S
    Pureza:97.24% - 99.83%
    Forma y color:Solid
    Peso molecular:379.48
  • SEC inhibitor KL-1

    CAS:
    <p>KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.</p>
    Fórmula:C18H16ClNO4
    Pureza:97.42%
    Forma y color:Solid
    Peso molecular:345.78
  • Tomivosertib HCl

    CAS:
    <p>Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.</p>
    Fórmula:C17H21ClN6O2
    Forma y color:Solid
    Peso molecular:376.845
  • Dienogest

    CAS:
    <p>Dienogest (STS 557), an oral 4th-gen progestogen, is used in hormone therapy and contraception with antiandrogenic effects.</p>
    Fórmula:C20H25NO2
    Pureza:98% - 99.43%
    Forma y color:Pale Yellow Solid
    Peso molecular:311.42
  • AZD-3463

    CAS:
    <p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>
    Fórmula:C24H25ClN6O
    Pureza:99.13%
    Forma y color:Solid
    Peso molecular:448.95
  • EPI-001

    CAS:
    <p>EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ~6 μM and a selective PPAR-gamma modulator.</p>
    Fórmula:C21H27ClO5
    Pureza:99% - 99.67%
    Forma y color:Solid
    Peso molecular:394.89
  • Vesatolimod

    CAS:
    <p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>
    Fórmula:C22H30N6O2
    Pureza:97.46% - 99.03%
    Forma y color:Solid
    Peso molecular:410.51
  • WYE-354

    CAS:
    <p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (&gt;100x) and PI3Kγ (&gt;500x), sparing P-AKT(T308).</p>
    Fórmula:C24H29N7O5
    Pureza:97.86% - 99.61%
    Forma y color:Solid
    Peso molecular:495.53
  • Rabeprazole sodium

    CAS:
    <p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>
    Fórmula:C18H20N3NaO3S
    Pureza:98% - 99.912%
    Forma y color:White Or Off White Crystalline Powder
    Peso molecular:381.42
  • Simazine

    CAS:
    <p>Simazine (Tafazine), a chlorotriazine herbicide/pesticide, may cause reproductive harm, endocrine disruption, and cancer.</p>
    Fórmula:C7H12ClN5
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:201.66
  • Thalidomide-O-amido-C6-NH2 hydrochloride

    CAS:
    <p>Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.</p>
    Fórmula:C21H27ClN4O6
    Pureza:97.33%
    Forma y color:Solid
    Peso molecular:466.915
  • Garcinol

    CAS:
    <p>Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).</p>
    Fórmula:C38H50O6
    Pureza:98.59%
    Forma y color:Solid
    Peso molecular:602.8
  • SBI-0640756

    CAS:
    <p>SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.</p>
    Fórmula:C23H14ClFN2O2
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:404.82
  • Tenovin-1

    CAS:
    <p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>
    Fórmula:C20H23N3O2S
    Pureza:99.33%
    Forma y color:Solid
    Peso molecular:369.48
  • 2,5-dimethyl Celecoxib

    CAS:
    <p>2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.</p>
    Fórmula:C18H16F3N3O2S
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:395.4
  • B-AP15

    CAS:
    <p>B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.</p>
    Fórmula:C22H17N3O6
    Pureza:91.43% - 98.77%
    Forma y color:Solid
    Peso molecular:419.39
  • Sophocarpine

    CAS:
    <p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>
    Fórmula:C15H22N2O
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:246.35
  • CHIR-124

    CAS:
    <p>CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.</p>
    Fórmula:C23H22ClN5O
    Pureza:96.33% - 98.35%
    Forma y color:Solid
    Peso molecular:419.91
  • IC261

    CAS:
    <p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>
    Fórmula:C18H17NO4
    Pureza:99.45% - 99.91%
    Forma y color:Solid
    Peso molecular:311.33
  • Delanzomib

    CAS:
    <p>Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.</p>
    Fórmula:C21H28BN3O5
    Pureza:95.52% - 99.46%
    Forma y color:Solid
    Peso molecular:413.28
  • Semaglutide

    CAS:
    <p>Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).</p>
    Fórmula:C187H291N45O59
    Pureza:96.92% - 99.78%
    Forma y color:Solid
    Peso molecular:4114
  • Onvansertib

    CAS:
    <p>Onvansertib (NMS-1286937) is a PLK1 inhibitor with high selectivity and oral activity. Onvansertib has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C24H27F3N8O3
    Pureza:98.3% - 99.88%
    Forma y color:Solid
    Peso molecular:532.52
  • Linifanib

    CAS:
    <p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>
    Fórmula:C21H18FN5O
    Pureza:98% - 98.24%
    Forma y color:Solid
    Peso molecular:375.4
  • Gardenin B

    CAS:
    <p>Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .</p>
    Fórmula:C19H18O7
    Pureza:98.80% - 99.74%
    Forma y color:Solid
    Peso molecular:358.34
  • Salvigenin

    CAS:
    <p>Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.</p>
    Fórmula:C18H16O6
    Pureza:99.17% - 99.78%
    Forma y color:Solid
    Peso molecular:328.32
  • Afatinib

    CAS:
    <p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>
    Fórmula:C24H25ClFN5O3
    Pureza:98.56% - 99.9%
    Forma y color:Off-White Solid
    Peso molecular:485.94
  • Mitochonic acid 5

    CAS:
    <p>MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.</p>
    Fórmula:C18H13F2NO3
    Pureza:98.85%
    Forma y color:Solid
    Peso molecular:329.3
  • Hypericin

    CAS:
    <p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>
    Fórmula:C30H16O8
    Pureza:99.05% - ≥98%
    Forma y color:Red-Coloured Anthraquinone-Derivative
    Peso molecular:504.44
  • T0901317

    CAS:
    <p>T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).</p>
    Fórmula:C17H12F9NO3S
    Pureza:98% - 99.64%
    Forma y color:Solid
    Peso molecular:481.33
  • PATULIN

    CAS:
    <p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>
    Fórmula:C7H6O4
    Pureza:99.91% - 99.98%
    Forma y color:Compact Prisms Or Thick Plates From Ether Or Chloroform White Crystalline
    Peso molecular:154.12
  • Momordin Ic

    CAS:
    <p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>
    Fórmula:C41H64O13
    Pureza:98% - 99.69%
    Forma y color:Solid
    Peso molecular:764.94
  • Benzyl isothiocyanate

    CAS:
    <p>BITC, found in cruciferous veggies, exhibits anticancer, antimicrobial, and immunomodulatory effects.</p>
    Fórmula:C8H7NS
    Pureza:99.25% - 99.83%
    Forma y color:Clear Yellow Liquid
    Peso molecular:149.21
  • Pemetrexed disodium hemipenta hydrate

    CAS:
    <p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>
    Fórmula:C20H21N5O6·2NaH2O
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:518.43
  • PX-12

    CAS:
    <p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>
    Fórmula:C7H12N2S2
    Pureza:98% - 99.21%
    Forma y color:Solid
    Peso molecular:188.31
  • Neferine

    CAS:
    <p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>
    Fórmula:C38H44N2O6
    Pureza:98.81% - 99.65%
    Forma y color:Solid
    Peso molecular:624.77
  • PKR-IN-C16

    CAS:
    <p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>
    Fórmula:C13H8N4OS
    Pureza:97.8%
    Forma y color:Solid
    Peso molecular:268.29
  • Moexipril

    CAS:
    <p>Moexipril is an oral ACE inhibitor, lipid-soluble, targets plasma/tissue ACE, and is used for cardiovascular research.</p>
    Fórmula:C27H34N2O7
    Forma y color:Solid
    Peso molecular:498.57
  • Chrysosplenol D

    CAS:
    <p>Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.</p>
    Fórmula:C18H16O8
    Pureza:97.87% - 99.98%
    Forma y color:Solid
    Peso molecular:360.31
  • Nutlin-3

    CAS:
    <p>Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C30H30Cl2N4O4
    Pureza:98.13% - 99.89%
    Forma y color:Solid
    Peso molecular:581.49
  • Epoxomicin

    CAS:
    <p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>
    Fórmula:C28H50N4O7
    Pureza:98.65% - 98.86%
    Forma y color:White To Off-White Solid
    Peso molecular:554.72
  • BIX01294 (hydrochloride hydrate)

    CAS:
    <p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>
    Fórmula:C28H43Cl3N6O3
    Forma y color:Solid
    Peso molecular:618.04
  • Dacarbazine citrate

    CAS:
    <p>Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.</p>
    Fórmula:C12H18N6O8
    Forma y color:Solid
    Peso molecular:374.31
  • Helichrysetin

    CAS:
    <p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>
    Fórmula:C16H14O5
    Pureza:96.32% - ≥95%
    Forma y color:Solid
    Peso molecular:286.28
  • Anagrelide hydrochloride

    CAS:
    <p>Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.</p>
    Fórmula:C10H7Cl2N3O·HCl
    Pureza:99.58%
    Forma y color:Off-White Powder
    Peso molecular:292.55
  • DIM-C-pPhOH

    CAS:
    <p>CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.</p>
    Fórmula:C23H18N2O
    Pureza:98.61%
    Forma y color:Solid
    Peso molecular:338.4
  • PIK-75

    CAS:
    <p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>
    Fórmula:C16H14BrN5O4S
    Pureza:98.52% - >99.99%
    Forma y color:Solid
    Peso molecular:452.28
  • Evofosfamide

    CAS:
    <p>Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage and potentially induce apoptosis.</p>
    Fórmula:C9H16Br2N5O4P
    Pureza:98.74% - 99.75%
    Forma y color:Solid
    Peso molecular:449.04
  • Tandutinib

    CAS:
    <p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>
    Fórmula:C31H42N6O4
    Pureza:99.45% - ≥98%
    Forma y color:White Solid
    Peso molecular:562.7
  • LDN-57444

    CAS:
    <p>LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .</p>
    Fórmula:C17H11Cl3N2O3
    Pureza:97.8% - 99.87%
    Forma y color:Solid
    Peso molecular:397.64
  • DMU-212

    CAS:
    <p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>
    Fórmula:C18H20O4
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:300.35