Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
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Selonsertib
CAS:Producto controlado<p>Applications Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated.<br>References Nelson, C. H. et al.: Clin Pharmacol Ther. 98, 630 (2015); Lin, J. H., et al.: Nephron. 129, 29 (2015)<br></p>Fórmula:C24H24FN7OForma y color:NeatPeso molecular:445.496-(2-Hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine
CAS:Producto controlado<p>Applications An analogue of Olomoucine (Cat. # O567000) that acts as a potent inhibitor of Cdk 1 (IC50=100nm) and Cdk2 (IC50=80nm). Also displays antiproliferative and proapoptotic effects.<br>References Wermeulen, K., et al.: Leukemia, 16, 299(2002)<br></p>Fórmula:C18H24N6O2Forma y color:NeatPeso molecular:356.42N-Benzyloxycarbonyl-4-[(3R)-3-amino-1-oxo-4-(phenylthio)butyl]morpholine
CAS:<p>Applications Intermediate in the production of cell death regulators and apoptosis promoters.<br></p>Fórmula:C22H26N2O4SForma y color:Off White OilyPeso molecular:414.52N-(Ethoxycarbonylmethyl)piperazine
CAS:Producto controlado<p>Applications N-(Ethoxycarbonylmethyl)piperazine is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selective inducers of apoptosis and activators of procaspases for use as anticancer agents.<br>References Nakagawara, A., et al.: Cancer Res., 57, 4578 (1997), Denault, J., et al.: J. Biol. Chem., 278, 34042 (2003), Traven, A., et al.: Cancer Cell, 5, 107 (2004), Becattini, B., et al.: Chem. Biol., 11, 389 (2004),<br></p>Fórmula:C8H16N2O2Forma y color:NeatPeso molecular:172.22tert-Butyl 4-Bromo-2-fluorobenzoate
CAS:Producto controlado<p>Applications tert-Butyl 4-Bromo-2-fluorobenzoate is an intermediate of enzalutamide (M199800). Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Fórmula:C11H12BrFO2Forma y color:NeatPeso molecular:275.112-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexene-1-carboxaldehyde
CAS:Producto controlado<p>Applications 2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexene-1-carboxaldehyde is an intermediate in various reactions. For example, its an intermediate in preparation of N-(phenylsulfonyl)benzamides and N-(3-pyridylsulfonyl)benzamides as apoptosis-inducing agents for the treatment of cancer and immune diseases and autoimmune diseases.<br>References Bruncko, M., et al.: PCT Int. Appl. (2010), WO 2010138588 A2 20101202.<br></p>Fórmula:C15H17ClOForma y color:NeatPeso molecular:248.75Santamarine
CAS:<p>Applications Santamarine is a sesquiterpene lactone shows anticancer properties by inhibiting proliferation and inducing apoptosis.<br>References Mehmood, T., et al.: J. Cancer, 8, 1-11 (2017)<br></p>Fórmula:C15H20O3Forma y color:NeatPeso molecular:248.324-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]benzoic Acid
CAS:Producto controlado<p>Applications Intermediate in the production of cell death regulators and apoptosis promoters.<br>References Park, C., et al.: J. Med. Chem., 51, 6902 (2008),<br></p>Fórmula:C26H31ClN2O2Forma y color:NeatPeso molecular:438.99Aurintricarboxylic Acids (Technical Grade)
CAS:Producto controlado<p>Applications Aurintricarboxylic Acid is a cell-permeable apoptosis inhibitor.<br></p>Fórmula:C22H14O9Forma y color:NeatPeso molecular:422.34(R)-Irofulven
CAS:Producto controlado<p>Applications Semi-synrhetic antitumor agent derived from Illudin S. Inhibits DNA synthesis and induces apoptosis in tumor cells. Antineoplastic.<br>References Woynarowski, J.M., et al.: Biochem. Pharmacol., 54, 1181 (1997), Alexandre, J., et al.: Clin. Cancer Res., 10, 3377 (2004), Senzer, N., et al.: Am. J. Clin. Oncol., 28, 36 (2005),<br></p>Fórmula:C15H18O3Forma y color:NeatPeso molecular:246.312',5'-Dimethoxyacetophenone
CAS:Producto controladoFórmula:C10H12O3Forma y color:NeatPeso molecular:180.24-Methyl-1H-Imidazole-5-Carboxylic Acid Hydrate
CAS:Producto controlado<p>Applications 4-Methyl-1H-imidazole-5-carboxylic Acid is used in preparation of Cyclohexyl Benzamide compounds for treatment of type II diabetes. Also, used in preparation of Triazolylphenyl substituted Amides as apoptosis signal-regulating kinase inhibitors.<br>References Hu, Z., et al.: PCT Int. Appl.,(2018); Corkey, B., et al.: U.S., (2015);<br></p>Fórmula:C5H6N2O2·xH2OForma y color:NeatPeso molecular:126.11 + x(18.02)20(S)-Ginsenoside F2
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Ginsenoside F2 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to regulate element-binding protein cleavage activating protein and transforming growth factor-β pathways. This control over apoptosis can lead to a control over hair growth and hair loss in mammals.<br>References Shin, H. et al.: Biol. Pharm. Bull., 37, 755 (2014); Shin, H. et al.: Eur. J. Pharm., 730, 82 (2014);<br></p>Fórmula:C42H72O13Forma y color:NeatPeso molecular:785.01Melittin Trifluoroacetic Acid Salt (~80%)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications MelittinTrifluoroacetic Acid Salt is the Trifluoroacetic Acid Salt version of Melittin which is an apoptosis inducer, a NF-κB inhibitor, and a PLA2 activator.<br>References Han, S., et al.: J Asian Nat Prod Res. 11, 796-804 (2009); Park, C., et al.: Biochem. Biophys. Res. Commun., 394, 170-172 (2010); Park, J.H., et al.: Mol. Cells., 29, 209-215 (2010);<br></p>Fórmula:C131H229N39O31·x(C2HF3O2)Pureza:~80%Forma y color:NeatPeso molecular:2846.46 + x(114.02)Delanzomib
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Delanzomib is an orally active proteasome inhibitor. Delanzomib has been shown to down-modulate NF-κB, induce apoptosis, inhibit angiogenesis and M-CSF-RANKL-induced osteoclastogenesis.<br>References Piva, R. et al.: Blood, 111, 2765 (2008); Sanchez, E. et al.: Br. J. Haematol., 148, 569 (2010);<br></p>Fórmula:C21H28BN3O5Forma y color:NeatPeso molecular:413.28SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Forma y color:Orange PowderPeso molecular:568.09Riviciclib hydrochloride
CAS:<p>Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.</p>Fórmula:C21H20ClNO5·HClPureza:99.51%Forma y color:SolidPeso molecular:438.3Cot inhibitor-2
CAS:<p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>Fórmula:C26H25Cl2FN8Pureza:98.87%Forma y color:SolidPeso molecular:539.43Camptothecin
CAS:<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Fórmula:C20H16N2O4Pureza:99.52% - 99.88%Forma y color:Solid PowderPeso molecular:348.35Flurochloridone
CAS:<p>Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.</p>Fórmula:C12H10Cl2F3NOPureza:99.86%Forma y color:SolidPeso molecular:312.12Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Fórmula:C22H14Pureza:99.97%Forma y color:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Peso molecular:278.35SAR405838
CAS:MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.Fórmula:C29H34Cl2FN3O3Pureza:98.63%Forma y color:SolidPeso molecular:562.5L-Cystathionine
CAS:<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Fórmula:C7H14N2O4SPureza:96.43% - >99.99%Forma y color:SolidPeso molecular:222.26NPB
CAS:<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Fórmula:C29H31Cl2N3O2Pureza:99.93%Forma y color:SolidPeso molecular:524.48(Z)-4EGI-1
CAS:<p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>Fórmula:C18H12Cl2N4O4SForma y color:SolidPeso molecular:451.28CDK6/PIM1-IN-1
CAS:<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Fórmula:C25H28FN9Forma y color:SolidPeso molecular:473.55TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Fórmula:C18H9Cl4N5OForma y color:SolidPeso molecular:453.11Ramentaceone
CAS:<p>Ramentaceone is an antineoplastic.</p>Fórmula:C11H8O3Pureza:98%Forma y color:SolidPeso molecular:188.18AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Fórmula:C25H20N4O2Pureza:98%Forma y color:SolidPeso molecular:408.45MDM2-p53-IN-16
CAS:<p>MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.</p>Fórmula:C32H33N3O5Forma y color:SolidPeso molecular:539.62CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Forma y color:SolidPeso molecular:295.76YLT205
CAS:<p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>Fórmula:C16H12BrClN4O2S2Pureza:98%Forma y color:SolidPeso molecular:471.78MPT0B214
CAS:<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Fórmula:C20H20N2O5Forma y color:SolidPeso molecular:368.38PD-1/PD-L1-IN-29
CAS:<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Fórmula:C26H24N2O6Forma y color:SolidPeso molecular:460.48MR2938
CAS:<p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>Fórmula:C21H24N4O3Forma y color:SolidPeso molecular:380.44CCT373566
CAS:<p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.</p>Fórmula:C26H29ClF2N6O3Forma y color:SolidPeso molecular:547Apoptotic agent-3
CAS:<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Fórmula:C31H21N5OSForma y color:SolidPeso molecular:511.6PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Fórmula:C16H10Cl2N2OSPureza:98%Forma y color:SolidPeso molecular:349.23CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Fórmula:C22H18N2O3Forma y color:SolidPeso molecular:358.39K145
CAS:<p>K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.</p>Fórmula:C18H24N2O3SPureza:98%Forma y color:SolidPeso molecular:348.46Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Forma y color:SolidPeso molecular:424.44TrxR inhibitor D9
CAS:<p>TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).</p>Fórmula:C25H20AuOPSForma y color:SolidPeso molecular:596.43BMS-566394
CAS:<p>BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).</p>Fórmula:C22H21F3N4O4Forma y color:SolidPeso molecular:462.42p53 Activator 2
CAS:<p>p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.</p>Fórmula:C20H21N5O2Forma y color:SolidPeso molecular:363.41ORY-1001 free base
CAS:<p>ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).</p>Fórmula:C15H22N2Pureza:98%Forma y color:SolidPeso molecular:230.35QTX125
CAS:<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Fórmula:C23H19N3O5Forma y color:SolidPeso molecular:417.41Topoisomerase II inhibitor 7
CAS:<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Fórmula:C32H28BrN5O5SForma y color:SolidPeso molecular:674.56ATX inhibitor 13
CAS:<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Fórmula:C31H35Cl2N5O3Forma y color:SolidPeso molecular:596.55RIPK1-IN-13
CAS:<p>RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.</p>Fórmula:C21H20ClN3O3Forma y color:SolidPeso molecular:397.85Aurora kinase-IN-1
<p>Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.</p>Fórmula:C30H25Br2N3O5Forma y color:SolidPeso molecular:667.34PD173952
CAS:<p>PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.</p>Fórmula:C24H21Cl2N5O2Pureza:99.5%Forma y color:SolidPeso molecular:482.36PI3K inhibitor C 96
CAS:<p>PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.</p>Fórmula:C11H8N2O3SPureza:98%Forma y color:SolidPeso molecular:248.26(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Fórmula:C25H26F2N4O3Forma y color:SolidPeso molecular:468.5A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Fórmula:C16H26N4O3Pureza:96.29%Forma y color:SolidPeso molecular:322.4Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Fórmula:C4H10ClNO2SePureza:98%Forma y color:SolidPeso molecular:218.54SAHA-OH
CAS:<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Fórmula:C15H22N2O4Pureza:98%Forma y color:SolidPeso molecular:294.35p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C29H32F6N4OForma y color:SolidPeso molecular:566.58Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Fórmula:C9H9NO3Forma y color:SolidPeso molecular:179.17BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Fórmula:C30H23Cl2FN4O4Forma y color:SolidPeso molecular:593.43PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Fórmula:C34H51NO2Forma y color:SolidPeso molecular:505.77ATSP-7041
CAS:<p>ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)</p>Fórmula:C87H125N17O21Forma y color:SolidPeso molecular:1745.02GEM144
CAS:<p>GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.</p>Fórmula:C28H31NO5Forma y color:SolidPeso molecular:461.55Tigilanol tiglate
CAS:<p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>Fórmula:C30H42O10Pureza:98%Forma y color:SolidPeso molecular:562.65BMS-37
CAS:<p>BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.</p>Fórmula:C27H32N2O4Forma y color:SolidPeso molecular:448.55Cadein1
<p>Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.</p>Fórmula:C33H48F2INO2Forma y color:SolidPeso molecular:655.64MMP2-IN-1
CAS:MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Fórmula:C15H13NO5SForma y color:SolidPeso molecular:319.33Bcl-2/Mcl-1-IN-2
CAS:<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Fórmula:C26H24ClNO3Forma y color:SolidPeso molecular:433.93AV123
CAS:AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.Fórmula:C11H14N4O2Forma y color:SolidPeso molecular:234.252'-Deoxyadenosine
CAS:<p>2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.</p>Fórmula:C10H13N5O3Pureza:99.71%Forma y color:SolidPeso molecular:251.24Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Fórmula:C32H30F6N4O4Forma y color:SolidPeso molecular:648.6Quinidine polygalacturonate
CAS:Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.Fórmula:C26H34N2O9Forma y color:SolidPeso molecular:518.22643RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Fórmula:C30H30Cl2FN5O4Pureza:98%Forma y color:SolidPeso molecular:614.49TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Fórmula:C30H38N6OPureza:98%Forma y color:SolidPeso molecular:498.66ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Fórmula:C17H15N3O2Forma y color:SolidPeso molecular:293.32Anticancer agent 83
CAS:<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Fórmula:C20H19N5OSForma y color:SolidPeso molecular:377.46c-Met-IN-14
CAS:<p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>Fórmula:C34H38ClFN4O7SForma y color:SolidPeso molecular:701.2LLP-3
CAS:<p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>Fórmula:C32H23ClN2O4Forma y color:SolidPeso molecular:534.99Antioxidant agent-5
CAS:<p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>Fórmula:C24H24N6OForma y color:SolidPeso molecular:412.49ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Fórmula:C17H16N2O3Forma y color:SolidPeso molecular:296.32Cl-amidine
CAS:<p>Cl-amidine, an oral PAD inhibitor (IC50: 0.8-6.2 μM for PAD1/3/4), induces apoptosis in cancer cells.</p>Fórmula:C14H19ClN4O2Pureza:98%Forma y color:SolidPeso molecular:310.78HLI98C
CAS:<p>HLI98C is a HDM2 ubiquitin ligase inhibitor with anti-tumor activity.</p>Fórmula:C17H9ClN4O4Forma y color:SolidPeso molecular:368.73EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Fórmula:C28H28Cl2N6OForma y color:SolidPeso molecular:535.47IDO1/TDO-IN-1
CAS:<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Fórmula:C21H16O6Forma y color:SolidPeso molecular:364.35Alteminostat
CAS:<p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>Fórmula:C27H36N6O3Forma y color:SolidPeso molecular:492.61Topoisomerase II inhibitor 10
CAS:<p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>Fórmula:C27H20N6O7SForma y color:SolidPeso molecular:572.55DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Fórmula:C23H20N2O6SPureza:98.49% - 99.1%Forma y color:SolidPeso molecular:452.48DMH2
CAS:<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Fórmula:C27H25N5O2Pureza:98%Forma y color:SolidPeso molecular:451.52TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Fórmula:C20H17FN4O2Pureza:98%Forma y color:SolidPeso molecular:364.37Docetaxel trihydrate
CAS:<p>Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.</p>Fórmula:C43H59NO17Pureza:98.68% - >99.99%Forma y color:White Crystalline PowderPeso molecular:861.95BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Fórmula:C33H38BrFN4OForma y color:SolidPeso molecular:605.58SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Fórmula:C31H22N2O2Forma y color:SolidPeso molecular:454.52CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Fórmula:C35H53N7O7Forma y color:SolidPeso molecular:683.84SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Fórmula:C20H25ClN6OForma y color:SolidPeso molecular:400.91MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Forma y color:SolidPeso molecular:669.8ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Fórmula:C20H26N2O5SPureza:98.26%Forma y color:SolidPeso molecular:406.5Anticancer agent 72
CAS:<p>Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.</p>Fórmula:C20H19N7O2Forma y color:SolidPeso molecular:389.41MI-63
CAS:<p>MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.</p>Fórmula:C29H35Cl2FN4O3Forma y color:SolidPeso molecular:577.52p-nitro-Pifithrin-α
CAS:<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Fórmula:C15H16BrN3O3SForma y color:SolidPeso molecular:398.27S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Fórmula:C13H15F2N3O6S2Pureza:98%Forma y color:SolidPeso molecular:411.4Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Fórmula:C28H32N4OForma y color:SolidPeso molecular:440.58Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Fórmula:C27H22ClN3O4Pureza:98%Forma y color:SolidPeso molecular:487.93Selicrelumab
CAS:<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Pureza:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Forma y color:LiquidNSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Fórmula:C26H32N4O2SPureza:98%Forma y color:SolidPeso molecular:464.62TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSForma y color:SolidPeso molecular:379.48PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Fórmula:C25H28F3N3O6Forma y color:SolidPeso molecular:523.5CDK/HDAC-IN-2
CAS:<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Fórmula:C25H20Cl2N6O3Forma y color:SolidPeso molecular:523.37IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Fórmula:C21H28N4O2Forma y color:SolidPeso molecular:368.47Anti-inflammatory agent 22
CAS:<p>Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.</p>Fórmula:C22H16O6Forma y color:SolidPeso molecular:376.36VO-OHPic
CAS:<p>VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.</p>Fórmula:C12H10N2O8VForma y color:SolidPeso molecular:361.16Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Fórmula:C19H16Cl2N2O3Forma y color:SolidPeso molecular:391.25GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Fórmula:C24H28N4O3Forma y color:SolidPeso molecular:420.5Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Fórmula:C27H26ClNO4Forma y color:SolidPeso molecular:463.95cRIPGBM
CAS:<p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>Fórmula:C26H20FN2O2Pureza:98%Forma y color:SolidPeso molecular:411.45DPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Fórmula:C24H14N2O2Pureza:98.08%Forma y color:SolidPeso molecular:362.38Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Fórmula:C20H18ClN3O3Forma y color:SolidPeso molecular:383.83(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Fórmula:C20H18O6Forma y color:SolidPeso molecular:354.35(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Fórmula:C12H14N2O2Forma y color:SolidPeso molecular:218.25PI3Kδ-IN-11
CAS:<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Fórmula:C27H21N5OForma y color:SolidPeso molecular:431.49PI3K-IN-33
CAS:<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Fórmula:C23H21BrN6O2Forma y color:SolidPeso molecular:493.36CMC2.24
CAS:<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Fórmula:C26H21NO5Forma y color:SolidPeso molecular:427.45Antitumor agent-57
CAS:<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Fórmula:C20H15NO5Forma y color:SolidPeso molecular:349.34AP23464
CAS:<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Fórmula:C26H30N5O2PForma y color:SolidPeso molecular:475.52CZS-241
<p>CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.</p>Fórmula:C26H24ClF2N9OForma y color:SolidPeso molecular:551.98Berubicin HCl
CAS:<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Fórmula:C34H36ClNO11Forma y color:SolidPeso molecular:670.1HIOC
CAS:<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Fórmula:C16H19N3O3Forma y color:SolidPeso molecular:301.34AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Fórmula:C17H15N5SForma y color:SolidPeso molecular:321.4AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Fórmula:C22H32O2Forma y color:SolidPeso molecular:328.49HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Fórmula:C32H45N7O4Forma y color:SolidPeso molecular:591.74Metallo-β-lactamase-IN-5
CAS:<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Fórmula:C19H16N4O3Forma y color:SolidPeso molecular:348.36EGFR-IN-57
CAS:<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Fórmula:C22H15N3O2SForma y color:SolidPeso molecular:385.44RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H28N8O2Forma y color:SolidPeso molecular:496.56Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Fórmula:C18H13ClF3N5OForma y color:SolidPeso molecular:407.78Z-LEVD-FMK
CAS:<p>Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.</p>Fórmula:C31H45FN4O10Forma y color:SolidPeso molecular:652.71Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Fórmula:C31H34Cl2N6O3P2RuForma y color:SolidPeso molecular:772.56CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Forma y color:SolidPeso molecular:261.27PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Fórmula:C20H22N6O4Pureza:98%Forma y color:SolidPeso molecular:410.43ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Fórmula:C24H32N4O3Forma y color:SolidPeso molecular:424.54Arylquin 1
CAS:<p>Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.</p>Fórmula:C17H16FN3Forma y color:SolidPeso molecular:281.33Ludartin
CAS:<p>Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.</p>Fórmula:C15H18O3Forma y color:SolidPeso molecular:246.3Tubulin polymerization-IN-17
CAS:<p>Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.</p>Fórmula:C26H23NO5Forma y color:SolidPeso molecular:429.46PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Forma y color:SolidPeso molecular:468.5Topoisomerase II inhibitor 11
CAS:<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Fórmula:C27H21BrCl2N2O2SForma y color:SolidPeso molecular:588.34Mammea A/BA
CAS:<p>Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.</p>Fórmula:C25H26O5Forma y color:SolidPeso molecular:406.47AFG206
CAS:AFG206 is the novel first-generation type II" FLT3 inhibitor."Fórmula:C20H19N3O2Forma y color:SolidPeso molecular:333.38Aurora A inhibitor 2
CAS:<p>Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).</p>Fórmula:C24H26N6O3Forma y color:SolidPeso molecular:446.5Antitumor agent-56
CAS:<p>Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.</p>Fórmula:C28H28N2O10SForma y color:SolidPeso molecular:584.59PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Fórmula:C29H26N6O3Forma y color:SolidPeso molecular:506.56Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Fórmula:C28H26O8Forma y color:SolidPeso molecular:490.5CX-5011
CAS:<p>CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].</p>Fórmula:C20H12N4O2Pureza:98%Forma y color:SolidPeso molecular:340.33RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Fórmula:C23H24N4O4SForma y color:SolidPeso molecular:452.53Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Fórmula:C32H33NO5SForma y color:SolidPeso molecular:543.67PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Fórmula:C11H17N5O8Pureza:98%Forma y color:SolidPeso molecular:347.28UCB-6876
CAS:<p>UCB-6876 inhibits TNF signaling, stabilizes trimer asymmetry, shows concentration response, and is selective for TNFR1.</p>Fórmula:C17H18N2OForma y color:SolidPeso molecular:266.34ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Fórmula:C11H13NSeForma y color:SolidPeso molecular:238.19DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Fórmula:C22H24N2O3SForma y color:SolidPeso molecular:396.5MI-3
CAS:<p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>Fórmula:C18H25N5S2Pureza:98.66% - 99.61%Forma y color:SolidPeso molecular:375.55CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Forma y color:SolidPeso molecular:392.47PD-1/PD-L1-IN 5
CAS:<p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>Fórmula:C22H18N4O3SForma y color:SolidPeso molecular:418.47NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Forma y color:SolidPeso molecular:495.49SZM-1209
CAS:<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Fórmula:C31H29F5N4O5S2Pureza:98%Forma y color:SolidPeso molecular:696.71PI3Kδ/γ-IN-3
CAS:<p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>Fórmula:C23H20ClN9OForma y color:SolidPeso molecular:473.92Justicidin B
CAS:<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Fórmula:C21H16O6Forma y color:SolidPeso molecular:364.35Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Fórmula:C20H18O5Forma y color:SolidPeso molecular:338.35Anticancer agent 58
<p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>Fórmula:C39H55NO5Forma y color:SolidPeso molecular:617.86PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Forma y color:SolidPeso molecular:430.46hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Fórmula:C13H13N3O6P2SForma y color:SolidPeso molecular:401.27IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Fórmula:C22H23N3O3S2Forma y color:SolidPeso molecular:441.57Mps1-IN-5
CAS:<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Fórmula:C24H25N9Forma y color:SolidPeso molecular:439.52GK563
CAS:<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Fórmula:C16H22O2Forma y color:SolidPeso molecular:246.34hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Forma y color:SolidPeso molecular:419.43Thioxodihydroquinazolinone-19
CAS:<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Fórmula:C16H14N2OSPureza:98%Forma y color:SolidPeso molecular:282.36Anticancer agent 99
CAS:<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Fórmula:C19H20F3N3O2Forma y color:SolidPeso molecular:379.38Caspase-3/7 activator 2
<p>Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.</p>Fórmula:C32H34N2O7Forma y color:SolidPeso molecular:558.62MRS 2693 trisodium salt
CAS:<p>MRS 2693 trisodium salt is a P2Y6 agonist.</p>Fórmula:C9H22IN5O12P2Pureza:98%Forma y color:SolidPeso molecular:581.15Luxeptinib
CAS:<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Fórmula:C25H17F4N5O2Forma y color:SolidPeso molecular:495.43CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Fórmula:C22H23NO2Forma y color:SolidPeso molecular:333.42EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Forma y color:SolidPeso molecular:501.54Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Forma y color:SolidPeso molecular:421.49Tubulin/MMP-IN-2
CAS:<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Fórmula:C40H48NO11PForma y color:SolidPeso molecular:749.78Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Fórmula:C26H23NOForma y color:SolidPeso molecular:365.47Anticancer agent 47
CAS:<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Fórmula:C19H14N2O4SForma y color:SolidPeso molecular:366.39BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Forma y color:SolidPeso molecular:674.76Verticillin A
CAS:<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Fórmula:C30H28N6O6S4Pureza:98%Forma y color:SolidPeso molecular:696.84SK-7041
CAS:<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Fórmula:C19H21N3O3Pureza:98%Forma y color:SolidPeso molecular:339.39PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Forma y color:SolidPeso molecular:374.97GW-3333
CAS:<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Fórmula:C22H36N4O4Pureza:98%Forma y color:SolidPeso molecular:420.55p-DDAP
CAS:<p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>Fórmula:C18H31NOPureza:98%Forma y color:SolidPeso molecular:277.44HDAC6-IN-4
CAS:<p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>Fórmula:C30H38N2O5Forma y color:SolidPeso molecular:506.63VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Fórmula:C26H21ClF3N5O3S2Forma y color:SolidPeso molecular:608.05AZD 1152 (hydrochloride)
CAS:<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Fórmula:C26H33Cl2FN7O6PForma y color:SolidPeso molecular:660.47VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Fórmula:C19H19FN2O2Forma y color:SolidPeso molecular:326.36SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Fórmula:C27H28F3N5O2Pureza:98%Forma y color:SolidPeso molecular:511.54RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Fórmula:C22H25FN8OPureza:98.31%Forma y color:SolidPeso molecular:436.49CAY10747
CAS:<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Fórmula:C42H48FNO6Forma y color:SolidPeso molecular:681.83CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OForma y color:SolidPeso molecular:472.5Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Fórmula:C9H12F2N3O7PForma y color:SolidPeso molecular:343.18MMP-9-IN-5
CAS:<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Fórmula:C27H20IN3O4Forma y color:SolidPeso molecular:577.37PK9327
CAS:<p>PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.</p>Fórmula:C21H22N2SForma y color:SolidPeso molecular:334.48
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