
Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(142 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(138 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(14 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(56 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5903 productos de "Apoptosis"
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Mancozeb
CAS:Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.Fórmula:C8H12MnN4S8ZnPureza:98%Forma y color:Grayish-Yellow PowderPeso molecular:541.08Olsalazine
CAS:<p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>Fórmula:C14H10N2O6Pureza:99.31%Forma y color:SolidPeso molecular:302.24SEC inhibitor KL-1
CAS:KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.Fórmula:C18H16ClNO4Pureza:97.42%Forma y color:SolidPeso molecular:345.78WYE-354
CAS:WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Fórmula:C24H29N7O5Pureza:97.86% - 99.61%Forma y color:SolidPeso molecular:495.53EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Forma y color:SolidPeso molecular:311.33Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Fórmula:C11H11NO4SPureza:98.71%Forma y color:SolidPeso molecular:253.27McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Forma y color:SolidPeso molecular:925.16CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Fórmula:C23H16N4OPureza:99.16%Forma y color:SolidPeso molecular:364.4TASIN-1
CAS:<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Fórmula:C18H28N2O3SPureza:99.86%Forma y color:SolidPeso molecular:352.49CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Fórmula:C15H20ClN5O4Pureza:99.1%Forma y color:Off-White To Light Yellow SolidPeso molecular:369.8Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Forma y color:White Crystalline PowderPeso molecular:610.66Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61NVP-ADW742
CAS:<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Fórmula:C28H31N5OPureza:96.14% - 98.70%Forma y color:SolidPeso molecular:453.58Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Forma y color:SolidPeso molecular:409.26TASIN-1 Hydrochloride
CAS:<p>TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated</p>Fórmula:C18H29ClN2O3SPureza:99.94%Forma y color:SolidPeso molecular:388.951R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Fórmula:C23H21ClN2O5Pureza:99.51%Forma y color:SolidPeso molecular:440.88Amcasertib
CAS:<p>Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.</p>Fórmula:C31H33N5O2SPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:539.69Paroxetine
CAS:Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.Fórmula:C19H20FNO3Pureza:98.59% - 98.89%Forma y color:White To Off-White PowderPeso molecular:329.37Parcetasal
CAS:Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.Fórmula:C17H15NO5Pureza:99.07%Forma y color:SolidPeso molecular:313.3Romidepsin
CAS:Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Forma y color:SolidPeso molecular:540.7TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFórmula:C17H18ClNO3SPureza:97.33%Forma y color:PowderPeso molecular:351.85PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Forma y color:SolidPeso molecular:188.31L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Fórmula:C13H13ClN4OSPureza:98.6% - 99.13%Forma y color:SolidPeso molecular:308.79PCNA-I1
CAS:<p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>Fórmula:C17H14N2O2SPureza:97.64%Forma y color:SolidPeso molecular:310.37Tilmicosin phosphate
CAS:<p>Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.</p>Fórmula:C46H83N2O17PPureza:95.29% - 97.13%Forma y color:Light Yellow PowderPeso molecular:967.1Elevenostat
CAS:<p>Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.</p>Fórmula:C16H17N3O4Pureza:95% - 96.14%Forma y color:SolidPeso molecular:315.32D-Saccharic acid 1,4-lactone hydrate
CAS:D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.Fórmula:C17H20ClN3OPureza:99.49% - ≥98%Forma y color:SolidPeso molecular:317.81Benzarone
CAS:Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.Fórmula:C17H14O3Pureza:99.77%Forma y color:SolidPeso molecular:266.293-hydroxy-3-phenylpentanamide
CAS:<p>Chiral 3-hydroxy-3-phenylpentanamide: neuroprotective, may treat anxiety/depression/addiction, anticancer.</p>Fórmula:C11H15NO2Pureza:98.42%Forma y color:SolidPeso molecular:193.24Isobutylparaben
CAS:<p>Isobutylparaben is a preservative and preservative insecticide.</p>Fórmula:C11H14O3Pureza:99.36%Forma y color:White CreamPeso molecular:194.23Quinocetone
CAS:<p>Quinocetone is an animal growth promoter and potential anti-tumor activity.</p>Fórmula:C18H14N2O3Pureza:98.06%Forma y color:SolidPeso molecular:306.32Ceftiofur
CAS:<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Fórmula:C19H17N5O7S3Pureza:98.26%Forma y color:SolidPeso molecular:523.56Dantrolene sodium hemiheptahydrate
CAS:Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFórmula:C14H9N4NaO5·5H2OPureza:99.72%Forma y color:Orange PowderPeso molecular:399.29GYY4137
CAS:GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with antihypertensive, anti-inflammatory and anticancer activity.Fórmula:C11H16NO2PS2·C4H9NOPureza:95.54% - 99.97%Forma y color:SolidPeso molecular:376.47DIM-C-pPhCO2Me
CAS:DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.Fórmula:C25H20N2O2Pureza:99.55% - 99.86%Forma y color:SolidPeso molecular:380.44Desciclovir
CAS:Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.Fórmula:C8H11N5O2Pureza:99.54%Forma y color:SolidPeso molecular:209.212-HBA
CAS:2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.Fórmula:C17H14O3Pureza:99.76%Forma y color:SolidPeso molecular:266.29NSC 3852
CAS:NSC 3852 is a potent inhibitor of histone deacetylase.Fórmula:C9H6N2O2Pureza:99.64%Forma y color:Slightly Yellow To Yellow-Green PowderPeso molecular:174.163,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Fórmula:C9H4Cl2O2Pureza:97.94%Forma y color:SolidPeso molecular:215.03Thalidomide-NH-CH2-COOH TFA
CAS:2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.Fórmula:C17H14F3N3O8Pureza:95.00%Forma y color:SolidPeso molecular:445.3036Hexamethylene bisacetamide
CAS:Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.Fórmula:C10H20N2O2Pureza:99.94%Forma y color:White FlakesPeso molecular:200.28PDL-1 cpd 10
CAS:<p>PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.</p>Fórmula:C21H23N5O2Pureza:97.08%Forma y color:SolidPeso molecular:377.44Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Fórmula:C35H41ClN6O4Pureza:99.52%Forma y color:SolidPeso molecular:645.19Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Fórmula:C24H30N2O2SPureza:99.9% - 99.92%Forma y color:SolidPeso molecular:410.57(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Fórmula:C18H15N5O6S2Pureza:97.62% - 98%Forma y color:SolidPeso molecular:461.47OTS964 hydrochloride
CAS:<p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>Fórmula:C23H24N2O2S·HClPureza:96.5% - 98.03%Forma y color:SolidPeso molecular:428.97Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Fórmula:C21H28FN3O7Pureza:98.24% - 99.79%Forma y color:SolidPeso molecular:453.46Sinapinic Acid
CAS:<p>Sinapinic Acid (Synapoic acid) is a phenolic isolated from the roots of Hydnophytum formicarumJack. It is an HDAC inhibitor and also inhibits ACE-I activity.</p>Fórmula:C11H12O5Pureza:99.88% - >99.99%Forma y color:SolidPeso molecular:224.21Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Fórmula:C14H11N3O3SPureza:98% - 99.91%Forma y color:Physical Description White Powder (Ntp 1992)Peso molecular:301.32Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Fórmula:C16H14N2O2Pureza:99.94% - >99.99%Forma y color:SolidPeso molecular:266.29
