Topoisomerasa
Las topoisomerasas son enzimas que regulan la topología del ADN durante procesos como la replicación, transcripción y segregación de cromosomas, introduciendo rupturas transitorias en las hebras de ADN para aliviar el estrés torsional. Los inhibidores de topoisomerasa interfieren con este proceso, lo que lleva a la acumulación de rupturas en el ADN y la inducción de la muerte celular, particularmente en células que se dividen rápidamente. Estos inhibidores se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer. En CymitQuimica, ofrecemos una amplia gama de inhibidores de topoisomerasa de alta calidad para apoyar su investigación en replicación del ADN, terapia contra el cáncer y regulación del ciclo celular.
Se han encontrado 140 productos de "Topoisomerasa"
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Enoxacin hydrate
CAS:<p>Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.</p>Fórmula:C15H17FN4O3H2OPureza:99.50%Forma y color:SolidPeso molecular:347.34Lurtotecan
CAS:<p>Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.</p>Fórmula:C28H30N4O6Pureza:99.18%Forma y color:SoildPeso molecular:518.56Nalidixic acid sodium salt
CAS:<p>Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.</p>Fórmula:C12H11N2NaO3Pureza:99.72% - 99.95%Forma y color:White To Off-White PowderPeso molecular:254.22Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFórmula:C27H29NO10·HClPureza:96.21% - 99.53%Forma y color:Cancer DrugPeso molecular:563.99Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.52%Forma y color:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Topotecan hydrochloride
CAS:<p>Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.</p>Fórmula:C23H24ClN3O5Pureza:97.88% - 99.41%Forma y color:White Crystalline SolidPeso molecular:457.92Nalidixic acid
CAS:Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.Fórmula:C12H12N2O3Pureza:99.9% - 99.95%Forma y color:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:232.24Gatifloxacin
CAS:Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.Fórmula:C19H22FN3O4Pureza:99.50% - 99.85%Forma y color:White PowderPeso molecular:375.39Hycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Fórmula:C20H24N2O2SPureza:98.78%Forma y color:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48Moxifloxacin hydrochloride
CAS:Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.Fórmula:C21H25ClFN3O4Pureza:99.91% - >99.99%Forma y color:SolidPeso molecular:437.89Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Fórmula:C20H18ClNO4Pureza:99.47% - 99.93%Forma y color:Yellow Crystalline PowderPeso molecular:371.80Oxaquin TEA
<p>Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and</p>Fórmula:C37H48F2N5O11PPureza:99.79%Forma y color:SolidPeso molecular:807.77Ciprofloxacin monohydrochloride
CAS:Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.Fórmula:C17H18FN3O3·HClPureza:99.5% - 99.73%Forma y color:White Or Light Yellow Crystalline PowderPeso molecular:367.80Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Fórmula:C17H18FN3O3Pureza:98.77% - 99.91%Forma y color:White PowderPeso molecular:331.34Mitoxantrone dihydrochloride
CAS:<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Forma y color:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Fórmula:C33H39ClN4O6Pureza:98% - 99.94%Forma y color:Yellow Crystalline PowderPeso molecular:623.14Lomefloxacin
CAS:Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.Fórmula:C17H19F2N3O3Pureza:98.59%Forma y color:Off-White To Yellow CrystalsPeso molecular:351.35Epirubicin hydrochloride
CAS:<p>Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C27H30ClNO11Pureza:98.13% - 99.79%Forma y color:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.98Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Fórmula:C33H45ClN4O9Pureza:98.22% - >99.99%Forma y color:Pale Yellow To Yellow Crystalline PowderPeso molecular:677.18Pefloxacin Mesylate
CAS:Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-Fórmula:C18H24FN3O6SPureza:99.86%Forma y color:SolidPeso molecular:429.46
