STAT
Las proteínas STAT son componentes críticos de la vía de señalización JAK/STAT, que transmite señales extracelulares de citoquinas y factores de crecimiento al núcleo celular, influyendo en la expresión génica. Las proteínas STAT están involucradas en la regulación de respuestas inmunitarias, crecimiento celular, diferenciación y supervivencia. La desregulación de la señalización STAT está implicada en diversas enfermedades, incluido el cáncer, trastornos autoinmunes e inflamación crónica. En CymitQuimica, ofrecemos una amplia gama de moduladores de la vía STAT para apoyar su investigación en transducción de señales, inmunología y desarrollo terapéutico.
Se han encontrado 109 productos para "STAT".
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Saikosaponin D
CAS:Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.Fórmula:C42H68O13Pureza:98.34% - 99.73%Forma y color:White SolidPeso molecular:780.9815Protosappanin A
CAS:Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Fórmula:C15H12O5Pureza:99.42% - 99.82%Forma y color:White SolidPeso molecular:272.2528AS1517499
CAS:AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!Fórmula:C20H20ClN5O2Pureza:98.27% - 99.3%Forma y color:SolidPeso molecular:397.858Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Fórmula:C30H52O3Pureza:98% - 99.9%Forma y color:SolidPeso molecular:460.73212-(1,8-naphthyridin-2-yl)phenol
CAS:2-NP is a STAT1 enhancer.Fórmula:C14H10N2OPureza:99.82% - 99.94%Forma y color:SolidPeso molecular:222.242BD750
CAS:BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM inFórmula:C14H13N3OSPureza:99.02%Forma y color:SolidPeso molecular:271.338FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Fórmula:C28H32O6Pureza:97.90% - 99.10%Forma y color:SolidPeso molecular:464.5501SH5-07
CAS:SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).Fórmula:C29H28F5N3O5SPureza:95.54%Forma y color:SolidPeso molecular:625.607Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Fórmula:C40H52O4Pureza:95.10% - 99.79%Forma y color:SolidPeso molecular:596.8385Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFórmula:C25H28O6Pureza:99.33% - 99.94%Forma y color:Yellow SolidPeso molecular:424.4862Stattic
CAS:Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Fórmula:C8H5NO4SPureza:98.32% - 99.76%Forma y color:SolidPeso molecular:211.195AS1810722
CAS:AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.Fórmula:C25H25F2N7OPureza:99.13%Forma y color:SolidPeso molecular:477.5091HJC0152 hydrochloride
CAS:HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.Fórmula:C15H14Cl3N3O4Pureza:99.01% - 99.06%Forma y color:SolidPeso molecular:406.6481-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Fórmula:C21H13ClF3N3O2Pureza:97.56%Forma y color:White SolidPeso molecular:431.795Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Fórmula:C15H18O2Pureza:97.55% - 99.92%Forma y color:White SolidPeso molecular:230.3022Picroside I
CAS:Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.Fórmula:C24H28O11Pureza:99.70% - 99.93%Forma y color:White SolidPeso molecular:492.4725Casticin
CAS:Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.Fórmula:C19H18O8Pureza:99.59% - ≥95%Forma y color:SolidPeso molecular:374.3414Fraxinellone
CAS:1.Fórmula:C14H16O3Pureza:99.35% - 99.88%Forma y color:Yellow SolidPeso molecular:232.275ML116
CAS:ML116 is a potent and selective STAT3 inhibitor.Fórmula:C18H19N3SPureza:99.49%Forma y color:SolidPeso molecular:309.429
