STAT
Las proteínas STAT son componentes críticos de la vía de señalización JAK/STAT, que transmite señales extracelulares de citoquinas y factores de crecimiento al núcleo celular, influyendo en la expresión génica. Las proteínas STAT están involucradas en la regulación de respuestas inmunitarias, crecimiento celular, diferenciación y supervivencia. La desregulación de la señalización STAT está implicada en diversas enfermedades, incluido el cáncer, trastornos autoinmunes e inflamación crónica. En CymitQuimica, ofrecemos una amplia gama de moduladores de la vía STAT para apoyar su investigación en transducción de señales, inmunología y desarrollo terapéutico.
Se han encontrado 98 productos de "STAT"
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Saikosaponin D
CAS:<p>Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.</p>Fórmula:C42H68O13Pureza:98.34% - 99.73%Forma y color:White PowderPeso molecular:780.98Protosappanin A
CAS:<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Fórmula:C15H12O5Pureza:99.42% - 99.82%Forma y color:SolidPeso molecular:272.25AS1517499
CAS:<p>AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!</p>Fórmula:C20H20ClN5O2Pureza:98.27% - 98.7%Forma y color:SolidPeso molecular:397.86BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Fórmula:C14H13N3OSPureza:99.02%Forma y color:SolidPeso molecular:271.34Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84AS1810722
CAS:<p>AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.</p>Fórmula:C25H25F2N7OPureza:99.13%Forma y color:SolidPeso molecular:477.511-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Fórmula:C21H13ClF3N3O2Pureza:99.41%Forma y color:SolidPeso molecular:431.8Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Fórmula:C15H18O2Pureza:97.55% - 99.92%Forma y color:SolidPeso molecular:230.3C188-9
CAS:<p>C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.</p>Fórmula:C27H21NO5SPureza:98.07% - >99.99%Forma y color:SolidPeso molecular:471.52Casticin
CAS:<p>Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.</p>Fórmula:C19H18O8Pureza:99.37% - ≥95%Forma y color:SolidPeso molecular:374.34Fraxinellone
CAS:<p>1.</p>Fórmula:C14H16O3Pureza:99.35% - 99.92%Forma y color:SolidPeso molecular:232.27Corylifol A
CAS:<p>1.</p>Fórmula:C25H26O4Pureza:97.19% - 99.5%Forma y color:SolidPeso molecular:390.47AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Forma y color:Yellow SolidPeso molecular:294.3Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Fórmula:C15H20O2Pureza:99.02% - 99.66%Forma y color:Crystalline PowderPeso molecular:232.32Angoline
CAS:<p>Angoline hydrochloride: IL6/STAT3 inhibitor, IC50: 11.56 μM, blocks STAT3 phosphorylation and cancer cell growth.</p>Fórmula:C22H21NO5Pureza:99.43% - 99.96%Forma y color:SolidPeso molecular:379.41Mogrol
CAS:<p>Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.</p>Fórmula:C30H52O4Pureza:99.85% - 99.90%Forma y color:SolidPeso molecular:476.73Colivelin
CAS:<p>Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).</p>Fórmula:C119H206N32O35Pureza:96.56%Forma y color:SolidPeso molecular:2645.1Stafia-1
CAS:<p>Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.</p>Fórmula:C24H27O10PPureza:98.08%Forma y color:SolidPeso molecular:506.44Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Fórmula:C19H14O4Pureza:99.21%Forma y color:SolidPeso molecular:306.31
