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Transportador de membrana / canal de iones

Transportador de membrana / canal de iones

Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.

Subcategorías de "Transportador de membrana / canal de iones"

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Se han encontrado 2293 productos de "Transportador de membrana / canal de iones"

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  • PHP 501 trifluoroacetate
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    PHP 501 trifluoroacetate

    CAS:
    <p>GABAA antagonist</p>
    Fórmula:C20H21N3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.4

    Ref: TM-T23152

  • ML-252 hydrochloride
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    ML-252 hydrochloride

    CAS:
    <p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>
    Fórmula:C20H24N2OHCl
    Forma y color:Solid
    Peso molecular:344.9

    Ref: TM-T85299

  • JYL-273
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    JYL-273

    CAS:
    JYL-273 is a TRPV1 agonist.
    Fórmula:C28H39NO4S
    Forma y color:Solid
    Peso molecular:485.68

    Ref: TM-T24236

  • Kv3 modulator 3
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    Kv3 modulator 3

    CAS:
    <p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>
    Fórmula:C19H18N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:350.37

    Ref: TM-T11789

  • CGP36216 hydrochloride
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    CGP36216 hydrochloride

    CAS:
    <p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>
    Fórmula:C5H15ClNO2P
    Forma y color:Solid
    Peso molecular:187.6

    Ref: TM-T84878

  • Licostinel
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    Licostinel

    CAS:
    <p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>
    Fórmula:C8H3Cl2N3O4
    Pureza:98.02%
    Forma y color:Solid
    Peso molecular:276.03

    Ref: TM-T27828

  • (R)-Vanzacaftor
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    (R)-Vanzacaftor

    CAS:
    <p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>
    Fórmula:C32H39N7O4S
    Forma y color:Solid
    Peso molecular:617.76

    Ref: TM-T84699

  • JT010
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    JT010

    CAS:
    <p>JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).</p>
    Fórmula:C16H19ClN2O3S
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:354.85

    Ref: TM-T15628

  • LOE 908 hydrochloride
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    LOE 908 hydrochloride

    CAS:
    <p>Broad spectrum cation channel blocker</p>
    Fórmula:C41H49ClN2O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:749.29

    Ref: TM-T22929

  • Oct4 inducer-2
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    Oct4 inducer-2

    CAS:
    <p>Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].</p>
    Fórmula:C14H16N2O2S
    Forma y color:Solid
    Peso molecular:276.35

    Ref: TM-T79208

  • P2X3 antagonist 34
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    P2X3 antagonist 34

    CAS:
    Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.
    Fórmula:C24H26F2N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:456.48

    Ref: TM-T10560

  • PZ-II-029
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    PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Fórmula:C18H15N3O3
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:321.33

    Ref: TM-T28479

  • A-1165442
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    A-1165442

    CAS:
    <p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>
    Fórmula:C22H20ClF2N3O2
    Forma y color:Solid
    Peso molecular:431.86

    Ref: TM-T14067

  • NaPi2b-IN-2
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    NaPi2b-IN-2

    CAS:
    <p>NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human</p>
    Fórmula:C41H47ClF3N5O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:814.36

    Ref: TM-T78146

  • Risevistinel
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    Risevistinel

    CAS:
    <p>Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative</p>
    Fórmula:C14H23N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:297.35

    Ref: TM-T79857

  • Dimethylamiloride
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    Dimethylamiloride

    CAS:
    <p>Dimethylamiloride is a specific inhibitor of antiporters [1].</p>
    Fórmula:C8H12ClN7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:257.68

    Ref: TM-T78139

  • PF-05105679
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    PF-05105679

    CAS:
    <p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>
    Fórmula:C26H21FN2O3
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:428.45

    Ref: TM-T16483

  • NO-711ME
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    NO-711ME

    CAS:
    <p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>
    Fórmula:C22H24N2O3
    Pureza:99.54%
    Forma y color:Solid
    Peso molecular:364.44

    Ref: TM-T24540

  • mGAT-IN-1
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    mGAT-IN-1

    CAS:
    <p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>
    Fórmula:C28H34ClN3O2S2
    Forma y color:Solid
    Peso molecular:544.17

    Ref: TM-T63832

  • 8-Pcpt-cGMP
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    8-Pcpt-cGMP

    CAS:
    <p>8-Pcpt-cGMP acts as an agonist for cyclic nucleotide-gated (CNG) channels with an EC50 of 0.5 μM and exhibits good membrane permeability. This compound is utilized in research to explore the role of CNG channels in visual and olfactory signal transduction.</p>
    Fórmula:C16H15ClN5O7PS
    Forma y color:Solid
    Peso molecular:487.81

    Ref: TM-T88702