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Transportador de membrana / canal de iones

Transportador de membrana / canal de iones

Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.

Subcategorías de "Transportador de membrana / canal de iones"

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Se han encontrado 2460 productos de "Transportador de membrana / canal de iones"

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  • Moxetomidate
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    Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Fórmula:C15H18N2O3
    Forma y color:Solid
    Peso molecular:274.315

    Ref: TM-T205308

  • Crinecerfont tosylate
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    Crinecerfont tosylate

    CAS:
    <p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>
    Fórmula:C34H36ClFN2O4S2
    Forma y color:Solid
    Peso molecular:655.242

    Ref: TM-T205414

  • (3S,6R)-NML
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    (3S,6R)-NML

    CAS:
    <p>(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.</p>
    Fórmula:C20H27NO
    Forma y color:Solid
    Peso molecular:297.435

    Ref: TM-T205321

  • Logo de CymitQuimica
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    URAT1 inhibitor 2

    URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.
    Fórmula:C21H18BrN3O2S
    Forma y color:Solid
    Peso molecular:456.36

    Ref: TM-T62825

  • Insecticidal agent 21
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    Insecticidal agent 21

    CAS:
    Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.
    Fórmula:C37H40ClN3O2
    Forma y color:Solid
    Peso molecular:594.185

    Ref: TM-T206704

  • ATPase-IN-5
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    ATPase-IN-5

    CAS:
    <p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>
    Fórmula:C10H10N4O3S
    Pureza:99.19%
    Forma y color:Solid
    Peso molecular:266.28

    Ref: TM-T204943

  • Logo de CymitQuimica
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    PDE1-IN-4

    PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.
    Fórmula:C33H33N3O4
    Forma y color:Solid
    Peso molecular:535.63

    Ref: TM-T63776

  • Logo de CymitQuimica
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    P2X receptor-1

    P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.
    Fórmula:C14H14ClN3O3S2
    Forma y color:Solid
    Peso molecular:371.86

    Ref: TM-T61490

  • 5-O-Desmethyl donepezil
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    5-O-Desmethyl donepezil

    CAS:
    <p>5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.</p>
    Fórmula:C23H27NO3
    Forma y color:Solid
    Peso molecular:365.465

    Ref: TM-T206238

  • ICA-105665
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    ICA-105665

    CAS:
    ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.
    Fórmula:C19H15F2N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:355.34

    Ref: TM-T11606

  • GNE-616
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    GNE-616

    CAS:
    <p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>
    Fórmula:C24H23F4N5O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:537.53

    Ref: TM-T11439

  • (RS)-AMPA hydrobromide
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    (RS)-AMPA hydrobromide

    CAS:
    AMPAR agonist
    Fórmula:C7H11BrN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:267.08

    Ref: TM-T23267

  • KV1.3-IN-2
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    KV1.3-IN-2

    CAS:
    <p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>
    Fórmula:C16H23ClN2O4
    Forma y color:Solid
    Peso molecular:342.818

    Ref: TM-T205655

  • Opakalim
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    Opakalim

    CAS:
    <p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>
    Fórmula:C18H22F2N4O
    Forma y color:Solid
    Peso molecular:348.39

    Ref: TM-T206117

  • Logo de CymitQuimica
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    WS-898

    <p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>
    Fórmula:C33H25N7OS
    Forma y color:Solid
    Peso molecular:567.66

    Ref: TM-T64016

  • Blixeprodil
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    Blixeprodil

    CAS:
    Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.
    Fórmula:C13H16FNO
    Forma y color:Solid
    Peso molecular:221.271

    Ref: TM-T206599

  • Logo de CymitQuimica
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    IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Fórmula:C16H13F6NO2
    Forma y color:Solid
    Peso molecular:365.27

    Ref: TM-T61393

  • Logo de CymitQuimica
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    VU0463271 quarterhydrate

    VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].
    Fórmula:C19H20N4O2S2
    Forma y color:Solid
    Peso molecular:387

    Ref: TM-T61725

  • V-ATPase-IN-1
    Targetmol
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    V-ATPase-IN-1

    CAS:
    <p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>
    Fórmula:C21H20ClNO2
    Forma y color:Solid
    Peso molecular:353.84

    Ref: TM-T200467

  • (S)-Albuterol
    Targetmol
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    (S)-Albuterol

    CAS:
    <p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>
    Fórmula:C13H21NO3
    Forma y color:Solid
    Peso molecular:239.311

    Ref: TM-T206288