Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(98 productos)
- Receptor de adiponectina(5 productos)
- CFTR(66 productos)
- Receptor CGRP(53 productos)
- Canal de calcio(525 productos)
- Canal de cloruro(51 productos)
- Receptor GABA(355 productos)
- Transportador de monoamina(26 productos)
- Transportador de monocarboxilato(18 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(9 productos)
- OAT(28 productos)
- OCT(7 productos)
- P-gp(52 productos)
- Canal de potasio(280 productos)
- Bomba de protones(40 productos)
- SGLT(31 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(94 productos)
Mostrar 13 subcategorías más
Se han encontrado 2430 productos de "Transportador de membrana / canal de iones"
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4'-hydroxy Trazodone
CAS:<p>4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is</p>Fórmula:C19H22ClN5O2Forma y color:SolidPeso molecular:387.87NAADP tetrasodium salt
CAS:Ca2+ mobilizing agentFórmula:C21H27N6O18P3Pureza:98%Forma y color:SolidPeso molecular:744.39ATP Synthesis-IN-1
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties.Forma y color:Odour SolidAnticancer agent 108
Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to bothFórmula:C18H9NO5S2Forma y color:SolidPeso molecular:383.4WAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Fórmula:C21H23N3O5Pureza:99.87%Forma y color:SolidPeso molecular:397.42Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.18GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Forma y color:Odour SolidMS7710
<p>MS7710 is a brain-penetrant inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. It reduces Ih current by inhibiting HCN channels, thereby decreasing the activity of dopamine neurons in the ventral tegmental area (VTA). MS7710 effectively improves social interaction deficits and reward-related cognitive flexibility in mouse models of chronic social defeat stress (CSDS) and shows promise for depression research.</p>Forma y color:Odour Solid8-Azido-ATP
CAS:8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties.Fórmula:C10H15N8O13P3Forma y color:SolidPeso molecular:548.19AR-C141990 hydrochloride
CAS:<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Fórmula:C26H29ClN4O4SForma y color:SolidPeso molecular:529.05AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Fórmula:C42H32FN3O7Pureza:98%Forma y color:SolidPeso molecular:709.72Idrevloride
CAS:Idrevloride (WO2016133967) inhibits ENaC, used in skin disorder research.Fórmula:C30H49ClN8O7Forma y color:SolidPeso molecular:669.22Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Forma y color:SolidPeso molecular:376.45Flufiprole
CAS:Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Fórmula:C16H10Cl2F6N4OSForma y color:SolidPeso molecular:491.24(2R,3S,11bS)-Dihydrotetrabenazine
CAS:<p>(2R,3S,11bS)-Tetrabenazine impurity, VMAT inhibitor for movement disorders.</p>Fórmula:C19H29NO3Pureza:99.29%Forma y color:SolidPeso molecular:319.44NF864
CAS:NF864, a suramin analog, is a P2X1 receptor inhibitor.Fórmula:C57H28N6Na12O41S12Pureza:98%Forma y color:SolidPeso molecular:2113.5Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Forma y color:Odour SolidAnticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Fórmula:C15H11N5OForma y color:SolidPeso molecular:277.28Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Fórmula:C29H42N8O4SPureza:98%Forma y color:SolidPeso molecular:598.76Ruzinurad
CAS:<p>Ruzinurad (WO2020088641, compound I) is a potent URAT1 inhibitor, exhibiting high selectivity.</p>Fórmula:C14H12BrNO2SForma y color:SolidPeso molecular:338.22
