Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(97 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(53 productos)
- Canal de calcio(520 productos)
- Canal de cloruro(51 productos)
- Receptor GABA(351 productos)
- Transportador de monoamina(26 productos)
- Transportador de monocarboxilato(18 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(9 productos)
- OAT(28 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(280 productos)
- Bomba de protones(40 productos)
- SGLT(31 productos)
- Canal de sodio(203 productos)
- Canal TRP / TRPV(94 productos)
Mostrar 13 subcategorías más
Se han encontrado 2402 productos de "Transportador de membrana / canal de iones"
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TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Fórmula:C11H8ClN3Forma y color:SolidPeso molecular:217.66Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Forma y color:SolidPeso molecular:376.45Conantokin G
CAS:GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.Fórmula:C88H138N26O44Pureza:98%Forma y color:White Lyophilised SolidPeso molecular:2264.21NF279
CAS:<p>P2X1 antagonist</p>Fórmula:C49H36N6Na6O23S6Pureza:98%Forma y color:SolidPeso molecular:1407.17Ampullosporin A
CAS:<p>Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.</p>Fórmula:C77H127N19O19Forma y color:SolidPeso molecular:1622.95JC-229
CAS:<p>JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).</p>Fórmula:C20H14Cl4N2O3SPureza:97.14%Forma y color:SolidPeso molecular:504.21(R)-Lanicemine
CAS:<p>(R)-Lanicemine ((R)-AZD6765), an R-enantiomer with less activity, is a low-trapping NMDA blocker with antidepressant effects.</p>Fórmula:C13H14N2Forma y color:SolidPeso molecular:198.26S-WJM992
<p>S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.</p>Fórmula:C22H18ClFN6O3Forma y color:SolidPeso molecular:468.87Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Fórmula:C169H278N54O48S8Pureza:98%Forma y color:SolidPeso molecular:4090.87Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Fórmula:C22H25ClN2O2Forma y color:SolidPeso molecular:384.9PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.Fórmula:C17H23N3Pureza:98%Forma y color:SolidPeso molecular:269.38ω-Agatoxin IVA
CAS:Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.Fórmula:C217H360N68O60S10Pureza:98%Forma y color:SolidPeso molecular:5202.25Huwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Fórmula:C161H246N48O44S6Pureza:98%Forma y color:SolidPeso molecular:3750.36JAMI1001A
CAS:JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.Fórmula:C16H17F3N4O3SForma y color:SolidPeso molecular:402.39TP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Fórmula:C16H15ClF2N6OForma y color:SolidPeso molecular:380.78P-gp inhibitor 15
P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123Fórmula:C35H60N2O4Forma y color:SolidPeso molecular:572.86Ouabagenin
CAS:<p>Ouabagenin, a naturally occurring LXR ligand with selective agonist activity, functions as an EC 3.6.3.9 (Na(+)/K(+)-transport ATPase) inhibitor [1] [2].</p>Fórmula:C23H34O8Forma y color:SolidPeso molecular:438.51GDC-0334
CAS:GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.Fórmula:C24H19F8N5O3SForma y color:SolidPeso molecular:609.5Roquefortine C
CAS:Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteinsFórmula:C22H23N5O2Pureza:98%Forma y color:SolidPeso molecular:389.45Way 125971
CAS:Way 125971 is a bioactive chemcial.Fórmula:C22H28N4O5S2Forma y color:SolidPeso molecular:492.61
