Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(52 productos)
- Canal de calcio(496 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(277 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2290 productos de "Transportador de membrana / canal de iones"
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SYM2206
CAS:<p>SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated</p>Fórmula:C20H22N4O3Pureza:99.88%Forma y color:SolidPeso molecular:366.41SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Fórmula:C16H16Cl2NO6PPureza:98.13%Forma y color:SolidPeso molecular:420.18Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Fórmula:C21H20F5N3O4Pureza:98.08% - 99.27%Forma y color:SolidPeso molecular:473.39(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFórmula:C19H27NO3Pureza:98.69%Forma y color:SolidPeso molecular:317.42(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Fórmula:C21H20BrNO6Forma y color:WhitePeso molecular:462.29A-887826
CAS:A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.Fórmula:C26H29ClN4O3Forma y color:SolidPeso molecular:480.995-Hydroxylansoprazole
CAS:<p>5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.</p>Fórmula:C16H14F3N3O3SPureza:99.00%Forma y color:SolidPeso molecular:385.36Umbellulone
CAS:Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.Fórmula:C10H14OPureza:98%Forma y color:SolidPeso molecular:150.22Indapamide
CAS:<p>Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.</p>Fórmula:C16H16ClN3O3SPureza:98.97% - 99.83%Forma y color:SolidPeso molecular:365.832-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Fórmula:C3H10NO3PPureza:98%Forma y color:SolidPeso molecular:139.091PF-06761281
CAS:<p>PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.</p>Fórmula:C13H17NO6Forma y color:SolidPeso molecular:283.283-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Fórmula:C6H8O4Pureza:98%Forma y color:SolidPeso molecular:144.13Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.51(Rac)-Lanicemine
CAS:<p>(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for the NMDA receptor and IC50 values of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].</p>Fórmula:C13H14N2Forma y color:SolidPeso molecular:198.26Verapamil EP Impurity C hydrochloride
CAS:<p>NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.</p>Fórmula:C12H20ClNO2Forma y color:SolidPeso molecular:245.75Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].</p>Fórmula:C10H15Cl4N5O2Pureza:99.30%Forma y color:SolidPeso molecular:379.07L-Cysteine S-sulfate sodium salt sesquihydrate
CAS:<p>L-Cysteine S-sulfate sodium salt sesquihydrate is a useful organic compound for research related to life sciences. The catalog number is T64782 and the CAS number is 150465-29-5.</p>Fórmula:C9H25N3Na3O17S6Forma y color:SolidPeso molecular:708.63Zastaprazan
CAS:<p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>Fórmula:C22H26N4OPureza:99.97%Forma y color:SolidPeso molecular:362.48GNE-9278
CAS:<p>GNE-9278 is a highly selective NMDAR orthosteric modulator that targets the GluN1 transmembrane structural domain (TMD), enhancing peak current and agonist affinity in activated NMDAR.</p>Fórmula:C21H27N5O3SForma y color:SolidPeso molecular:429.54Indoxacarb
CAS:<p>Indoxacarb is an Oxadiazine insecticide.</p>Fórmula:C22H17ClF3N3O7Pureza:98%Forma y color:SolidPeso molecular:527.83Dexivacaine
CAS:Dexivacaine is an type of anesthetic.Fórmula:C15H22N2OForma y color:SolidPeso molecular:246.35(±)-Vasicine
CAS:<p>(±)-Vasicine, the racemate of Vasicine, is isolated from Peganum harmala seeds and exhibits anti-ulcer activity.</p>Fórmula:C11H12N2OPureza:98%Forma y color:SolidPeso molecular:188.23Filapixant
CAS:<p>Filapixant, a purinoreceptor antagonist. This compound serves as the active reference substance for Eliapixant.</p>Fórmula:C24H26F3N5O3SForma y color:SolidPeso molecular:521.56Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Fórmula:C18H20NO3PSPureza:98%Forma y color:SolidPeso molecular:361.4Pazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Fórmula:C25H23ClN4O4Pureza:97.79% - 99.07%Forma y color:SolidPeso molecular:478.93CGP 44532
CAS:<p>CGP 44532 a GABAB receptor agonist.</p>Fórmula:C4H12NO3PPureza:98%Forma y color:SolidPeso molecular:153.12T16A(inh)-C01
CAS:<p>T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.</p>Fórmula:C18H16O5Pureza:98%Forma y color:SolidPeso molecular:312.32Motugivatrep
CAS:<p>Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.</p>Fórmula:C22H20F3NO3Pureza:99.22%Forma y color:SolidPeso molecular:403.39Gacyclidine
CAS:<p>Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.</p>Fórmula:C16H25NSPureza:99.85% - 99.92%Forma y color:SolidPeso molecular:263.44Phenamil methanesulfonate
CAS:<p>TRPP3 channel inhibitor</p>Fórmula:C13H16ClN7O4SPureza:98%Forma y color:SolidPeso molecular:401.83Pipequaline
CAS:<p>Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.</p>Fórmula:C22H24N2Pureza:98%Forma y color:SolidPeso molecular:316.44Ref: TM-T4655
Producto descatalogadoCMPDA
CAS:<p>CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].</p>Fórmula:C16H28N2O4S2Pureza:98%Forma y color:SolidPeso molecular:376.53Tifenazoxide
CAS:<p>Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.</p>Fórmula:C9H10ClN3O2S2Pureza:98%Forma y color:SolidPeso molecular:291.78HMR 1556
CAS:<p>HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).</p>Fórmula:C17H24F3NO5SForma y color:SolidPeso molecular:411.44CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Fórmula:C19H30NO5PPureza:98%Forma y color:SolidPeso molecular:383.42Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Fórmula:C26H37N3O2Pureza:98%Forma y color:SolidPeso molecular:423.59Ref: TM-T78670
Producto descatalogadoVMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Fórmula:C27H36F3NO6SPureza:98%Forma y color:SolidPeso molecular:559.64Ref: TM-T79061
Producto descatalogadoBumetanide sodium
CAS:<p>Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).</p>Fórmula:C17H19N2NaO5SForma y color:SolidPeso molecular:386.4LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Fórmula:C12H11N5OS2Pureza:98%Forma y color:SolidPeso molecular:305.38Belfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Fórmula:C27H50O7P2Pureza:98%Forma y color:SolidPeso molecular:548.63
