Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"
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UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Fórmula:C22H30BrClN2O5Forma y color:SolidPeso molecular:517.85ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Fórmula:C106H178N40O32S7·C2HF3O2Forma y color:SolidPeso molecular:2863.27Agitoxin-2
CAS:<p>Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).</p>Fórmula:C169H278N54O48S8Pureza:98%Forma y color:SolidPeso molecular:4090.87FD 12-9
CAS:<p>FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.</p>Fórmula:C51H47N3O11Pureza:98%Forma y color:SolidPeso molecular:877.93Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Fórmula:C49H75NO13Forma y color:SolidPeso molecular:886.133Cyclocreatine
CAS:<p>Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.</p>Fórmula:C5H9N3O2Pureza:99.864%Forma y color:SolidPeso molecular:143.14Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Fórmula:C79H131N31O24S4Pureza:98%Forma y color:SolidPeso molecular:2027.34Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Fórmula:C66H95N19O24Pureza:98.2%Forma y color:SolidPeso molecular:1538.57PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Fórmula:C17H23N3Pureza:98%Forma y color:SolidPeso molecular:269.38Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Fórmula:C272H429N85O84S10Pureza:98%Forma y color:SolidPeso molecular:6554.51TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Fórmula:C11H8ClN3Forma y color:SolidPeso molecular:217.66Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Fórmula:C10H19NO2Forma y color:SolidPeso molecular:185.26P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Fórmula:C35H60N2O4Forma y color:SolidPeso molecular:572.86(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Fórmula:C10H20ClNO2Pureza:99.26% - >99.99%Forma y color:SoildPeso molecular:221.72Roquefortine C
CAS:<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Fórmula:C22H23N5O2Pureza:98%Forma y color:SolidPeso molecular:389.45Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Fórmula:C17H16N6O3SForma y color:SolidPeso molecular:384.41AQP4 (201-220)
CAS:<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Fórmula:C97H143N27O27SForma y color:SolidPeso molecular:2151.4Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Fórmula:C18H27N5OForma y color:SolidPeso molecular:329.448LU-32-176B
CAS:<p>LU32-176B is a bioactive chemical.</p>Fórmula:C23H24F2N2O2Forma y color:SolidPeso molecular:398.45EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Fórmula:C22H20F4N2O3Forma y color:SolidPeso molecular:436.43-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Fórmula:C3H10NO2PForma y color:SolidPeso molecular:123.092D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Fórmula:C6H12Na2O12P2Forma y color:SolidPeso molecular:384.08(-)-(S)-Cibenzoline
CAS:<p>Cibenzoline, also known as Escibenzoline, is the S(+)-enantiomer of Cibenzoline and functions as an antiarrhythmic agent.</p>Fórmula:C18H18N2Forma y color:SolidPeso molecular:262.35Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Pureza:96.97%Forma y color:SolidElgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Fórmula:C29H33FN2O6Pureza:98.95% - 99.50%Forma y color:SolidPeso molecular:524.58GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Fórmula:C185H273N49O45S6Pureza:98%Forma y color:SolidPeso molecular:4095.84Conantokin-R
CAS:<p>Conantokin-R is an NMDA receptor peptide antagonist (IC50=93 nM); Conantokin-R exhibits anticonvulsant activity; Conantokin-R binds Zn2+ and Mg2+ (Kds 0.15 μM</p>Fórmula:C127H201N35O49S3Forma y color:SolidPeso molecular:3098.38Isotachysterol 3
CAS:<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Fórmula:C27H44OForma y color:SolidPeso molecular:384.64AVLX-125
CAS:<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Fórmula:C62H104N10O29Forma y color:SolidPeso molecular:1453.54S-Sulfo-L-cysteine sodium salt
CAS:<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Fórmula:C3H6NNaO5S2Pureza:99.88%Forma y color:SolidPeso molecular:223.2Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Fórmula:C28H44N2O2Pureza:99.88%Forma y color:SolidPeso molecular:440.666,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Fórmula:C10H9NO2Pureza:98.98%Forma y color:SolidPeso molecular:175.18URAT1 inhibitor 11
CAS:<p>URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.</p>Fórmula:C20H16F4N2O2Forma y color:SolidPeso molecular:392.35μ-Conotoxin SxIIIC
<p>μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including</p>Fórmula:C90H142N42O27S6Pureza:98%Forma y color:SolidPeso molecular:2436.75Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Fórmula:C32H49NO9Forma y color:SolidPeso molecular:591.742δ-Theraphotoxin-Hm1a toxin
<p>δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [</p>Fórmula:C170H240N48O53S6Pureza:98%Forma y color:SolidPeso molecular:3996.4Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Forma y color:SoildPeso molecular:532.523AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Fórmula:C20H25BrN4Forma y color:SolidPeso molecular:401.34GpTx-1
CAS:<p>GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].</p>Fórmula:C176H271N53O45S7Pureza:98%Forma y color:SolidPeso molecular:4073.82Heteropodatoxin-1
<p>Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9</p>Fórmula:C168H238N46O51S6Pureza:98%Forma y color:SolidPeso molecular:3910.35(S)-PF-03716556
CAS:<p>(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.</p>Fórmula:C22H26N4O3Pureza:99.8% - 99.91%Forma y color:SoildPeso molecular:394.47GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Forma y color:SolidPeso molecular:395.71Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Fórmula:C19H38ClN5O2SForma y color:SolidPeso molecular:436.06Astressin 2B
CAS:<p>CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.</p>Fórmula:C183H307N49O53Pureza:98%Forma y color:SolidPeso molecular:4041.69Nicardipine-d3 hydrochloride
CAS:<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Fórmula:C26H30ClN3O6Pureza:98%Forma y color:SolidPeso molecular:519Halofantrine hydrochloride
CAS:<p>Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.</p>Fórmula:C26H31Cl3F3NOPureza:98%Forma y color:SolidPeso molecular:536.89(S)-Nicardipine
CAS:<p>(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Fórmula:C26H29N3O6Forma y color:SolidPeso molecular:479.53Lubiprostone hemiketal
CAS:<p>Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.</p>Fórmula:C20H32F2O5Forma y color:SolidPeso molecular:390.46Ethacizine hydrochloride
CAS:<p>Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.</p>Fórmula:C22H28ClN3O3SPureza:98.08% - 98.08%Forma y color:SolidPeso molecular:449.99MRK-016
CAS:<p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>Fórmula:C17H20N8O2Pureza:99.76%Forma y color:SolidPeso molecular:368.39
