Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(98 productos)
- Receptor de adiponectina(5 productos)
- CFTR(66 productos)
- Receptor CGRP(54 productos)
- Canal de calcio(528 productos)
- Canal de cloruro(52 productos)
- Receptor GABA(360 productos)
- Transportador de monoamina(28 productos)
- Transportador de monocarboxilato(18 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(9 productos)
- OAT(31 productos)
- OCT(7 productos)
- P-gp(54 productos)
- Canal de potasio(280 productos)
- Bomba de protones(42 productos)
- SGLT(31 productos)
- Canal de sodio(206 productos)
- Canal TRP / TRPV(94 productos)
Mostrar 13 subcategorías más
Se han encontrado 2460 productos de "Transportador de membrana / canal de iones"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
1-Aminocyclobutanecarboxylic acid
CAS:<p>1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].</p>Fórmula:C5H9NO2Pureza:99.94%Forma y color:White To Tan Powder Crystals Crystalline Powder And/Or With ChunksPeso molecular:115.13Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Fórmula:C26H27F3N2O6Pureza:98.84% - >99.99%Forma y color:SolidPeso molecular:520.5MDK-4025
CAS:<p>MDK-4025 is an inhibitor of the high voltage-activated (HVA) Ca2+ current in pyramidal neurons.</p>Fórmula:C19H15ClOPureza:98.65%Forma y color:SolidPeso molecular:294.77Radiprodil
CAS:Radiprodil (RGH-896) is an oral NMDA NR2B antagonist for potential DPNP neuropathic pain treatment.Fórmula:C21H20FN3O4Pureza:99.74%Forma y color:SolidPeso molecular:397.4Memantine
CAS:Memantine treats moderate to severe Alzheimer's; it's an amantadine derivative blocking NMDA receptors.Fórmula:C12H21NPureza:≥98%Forma y color:White PowderPeso molecular:179.3Pipequaline hydrochloride
CAS:<p>Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative.</p>Fórmula:C22H25ClN2Pureza:99.46%Forma y color:SolidPeso molecular:352.9Trans-ACBD
CAS:Trans-ACBD (Trans-1-aminocyclobutane-1,3-dicarboxylic acid) is an effective and specific N-methyl-D-aspartate receptor agonist.Fórmula:C6H9NO4Pureza:99.47%Forma y color:SolidPeso molecular:159.14Phenibut (hydrochloride)
CAS:Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors.Fórmula:C10H14ClNO2Pureza:99.93%Forma y color:White Crystalline PowderPeso molecular:215.68(S)-(-)-5-Fluorowillardiine hydrochloride
CAS:(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific agonist of AMPAR.Fórmula:C7H9ClFN3O4Forma y color:SolidPeso molecular:253.62(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Fórmula:C14H14O3Pureza:97% - ≥95%Forma y color:White Fine PowderPeso molecular:230.26GNE-131
CAS:<p>GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).</p>Fórmula:C23H30N4O3SPureza:98.54% - 99.59%Forma y color:SolidPeso molecular:442.57XEN907
CAS:XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).Fórmula:C21H21NO4Pureza:99.92%Forma y color:SolidPeso molecular:351.4Lansoprazole sodium
CAS:Lansoprazole sodium is a PPI used to treat acid reflux and peptic ulcers.Fórmula:C16H13F3N3NaO2SPureza:99.14%Forma y color:SolidPeso molecular:391.34PF 05089771
CAS:PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.Fórmula:C18H12Cl2FN5O3S2Pureza:99.03% - 99.42%Forma y color:SolidPeso molecular:500.35Tegoprazan
CAS:<p>Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C20H19F2N3O3Pureza:98.22%Forma y color:SolidPeso molecular:387.38Esomeprazole magnesium salt
CAS:<p>Esomeprazole magnesium, an oral proton pump inhibitor, curbs gastric acid by blocking H+, K+-ATPase; used in treating GERD.</p>Fórmula:C17H21MgN3O3SForma y color:SolidPeso molecular:371.74Cinacalcet metabolite M4
CAS:<p>Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.</p>Fórmula:C10H12F3NPureza:97.13%Forma y color:SolidPeso molecular:203.2ML277
CAS:<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Fórmula:C23H25N3O4S2Pureza:99.35%Forma y color:SolidPeso molecular:471.59Acecainide hydrochloride
CAS:<p>Acecainide hydrochloride (NAPA) is the major hepatic metabolite of procainamide.Cost-effective and quality-assured.</p>Fórmula:C15H24ClN3O2Pureza:98.023% - 99.81%Forma y color:SolidPeso molecular:313.83Vonoprazan hydrochloride
CAS:<p>Vonoprazan hydrochloride is a potent PPI and P-CAB for treating acid-related diseases and H. pylori infection.</p>Fórmula:C17H17ClFN3O2SForma y color:SolidPeso molecular:381.85TC-I2000
CAS:<p>TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.</p>Fórmula:C23H18F4N2OPureza:99.778%Forma y color:SolidPeso molecular:414.4Indecainide hydrochloride
CAS:Indecainide hydrochloride is a cardiac depressant.Fórmula:C20H25ClN2OForma y color:SolidPeso molecular:344.885,7-Dichlorokynurenic acid
CAS:5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.Fórmula:C10H5Cl2NO3Pureza:99.71%Forma y color:SolidPeso molecular:258.06PF-01247324
CAS:PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).Fórmula:C13H10Cl3N3OPureza:99.22%Forma y color:SolidPeso molecular:330.6CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Fórmula:C13H13NO4Pureza:97.37%Forma y color:SolidPeso molecular:247.25(2S)-6-Prenylnaringenin
CAS:(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.Fórmula:C20H20O5Pureza:99.47%Forma y color:SolidPeso molecular:340.37AZD-9056 free base
CAS:AZD9056 is a potent, selective, orally bioavailable P2X7 receptor antagonist.Fórmula:C24H35ClN2O2Forma y color:SolidPeso molecular:419Songorine
CAS:Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.Fórmula:C22H31NO3Pureza:98% - 99.92%Forma y color:SolidPeso molecular:357.49IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Forma y color:SolidPeso molecular:232.69Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Fórmula:C18H13F6N3O2SPureza:99.69% - 99.7%Forma y color:SolidPeso molecular:449.37CGP52432
CAS:CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM).Fórmula:C15H24Cl2NO4PPureza:98.75%Forma y color:SolidPeso molecular:384.24VX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Fórmula:C21H17F4N2O7PPureza:97.58%Forma y color:SolidPeso molecular:516.34Zosuquidar
CAS:Zosuquidar (RS 33295-198) is a potent P-glycoprotein inhibitor with antitumor activity that inhibits tumor growth.Fórmula:C32H31F2N3O2Pureza:99.99%Forma y color:SolidPeso molecular:527.6α-Thujone
CAS:α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Fórmula:C10H16OPureza:97.02% - 98.41%Forma y color:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Benzocaine xHCl(94-09-7(free base))
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).Fórmula:C9H11NO2·xHClPureza:99.37%Forma y color:SolidPeso molecular:N/ABenzamil
CAS:Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.Fórmula:C13H14ClN7OPureza:99.79%Forma y color:SolidPeso molecular:319.75Felbamate
CAS:Felbamate (W-554) is an Anti-epileptic Agent.Fórmula:C11H14N2O4Pureza:99% - >99.99%Forma y color:White Powder SolidPeso molecular:238.24TCN 201
CAS:TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.Fórmula:C21H17ClFN3O4SPureza:98.5%Forma y color:SolidPeso molecular:461.89Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Fórmula:C41H72O2Pureza:99.65%Forma y color:SolidPeso molecular:597.01BRITE-338733
CAS:<p>BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria (IC50=4.7 μM) for the bacterial infections treatment.</p>Fórmula:C27H35N3O2Pureza:99.85%Forma y color:SolidPeso molecular:433.59Lumacaftor
CAS:Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.Fórmula:C24H18F2N2O5Pureza:99.48% - 99.68%Forma y color:SolidPeso molecular:452.41Senicapoc
CAS:Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.Fórmula:C20H15F2NOPureza:95.7% - 99.47%Forma y color:SolidPeso molecular:323.34ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Fórmula:C17H23NOPureza:>99.99%Forma y color:SolidPeso molecular:257.37Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Fórmula:C16H18N2O3Pureza:99.74%Forma y color:SolidPeso molecular:286.33Drotaverine hydrochloride
CAS:Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilationFórmula:C24H32ClNO4Pureza:99.81%Forma y color:Pale-Yellow Crystalline SolidPeso molecular:433.968DQP 1105
CAS:<p>DQP 1105 is a NMDA receptor antagonist.</p>Fórmula:C29H24BrN3O4Pureza:98.6%Forma y color:SolidPeso molecular:558.42Tricaine methanesulfonate
CAS:<p>Tricaine methanesulfonate (TMS/MS-222) is an anesthetic used in hatcheries and studies to immobilize fish for marking, transport, and invasive procedures.</p>Fórmula:C10H15NO5SPureza:99.259% - 99.86%Forma y color:White PowderPeso molecular:261.30(S)-(-)-5-Fluorowillardiine
CAS:(S)-(-)-5-Fluorowillardiine ((S)-5-Fluorowillardiine) is an AMPA receptor-specific agonistFórmula:C7H8FN3O4Pureza:99.69%Forma y color:Off-White SolidPeso molecular:217.152'MeO6MF
CAS:2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functionalFórmula:C17H14O3Pureza:99.28% - 99.63%Forma y color:SolidPeso molecular:266.29JNJ-17203212
CAS:JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Fórmula:C17H15F6N5OPureza:99.18%Forma y color:SolidPeso molecular:419.32
