Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"
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NaV1.7 inhibitor-1
CAS:<p>NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).</p>Fórmula:C23H30FNO4SPureza:99.89%Forma y color:SolidPeso molecular:435.55QX-314 chloride
CAS:<p>QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.</p>Fórmula:C16H27ClN2OPureza:99.73%Forma y color:SolidPeso molecular:298.85Riparin III
CAS:<p>Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models.</p>Fórmula:C16H17NO4Pureza:95.13%Forma y color:SolidPeso molecular:287.31Flumazenil
CAS:<p>Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous</p>Fórmula:C15H14FN3O3Pureza:99.72% - 99.98%Forma y color:Less Crystals Colourless CrystalsPeso molecular:303.29Ropivacaine
CAS:<p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>Fórmula:C17H26N2OPureza:97.75% - >99.99%Forma y color:SolidPeso molecular:274.40Afoxolaner
CAS:<p>Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.</p>Fórmula:C26H17ClF9N3O3Pureza:99.1% - 99.38%Forma y color:SolidPeso molecular:625.87Eleclazine hydrochloride
CAS:<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Fórmula:C21H17ClF3N3O3Pureza:99.86%Forma y color:SolidPeso molecular:451.83ML418
CAS:<p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>Fórmula:C19H24ClN3O3Pureza:99.3%Forma y color:SolidPeso molecular:377.87Azosemide
CAS:<p>Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B).</p>Fórmula:C12H11ClN6O2S2Pureza:99.84%Forma y color:SolidPeso molecular:370.84Linopirdine
CAS:<p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>Fórmula:C26H21N3OPureza:99.45% - 99.78%Forma y color:SolidPeso molecular:391.46DSP-2230
CAS:<p>DSP-2230 is a selective blocker of Nav1.7/Nav1.8.</p>Fórmula:C20H20F3N5O2Pureza:97.14%Forma y color:SolidPeso molecular:419.4Cycloleucine
CAS:<p>Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.</p>Fórmula:C6H11NO2Pureza:99.90%Forma y color:SolidPeso molecular:129.16VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Fórmula:C20H22ClFN4O2SPureza:98.1%Forma y color:SoildPeso molecular:436.93Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Fórmula:C21H29N3OPureza:99.62%Forma y color:SolidPeso molecular:339.47BI-749327
CAS:<p>BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).</p>Fórmula:C23H21F3N4O2Pureza:99.68%Forma y color:SolidPeso molecular:442.43ICA-27243
CAS:<p>ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.</p>Fórmula:C12H7ClF2N2OPureza:99.54%Forma y color:SolidPeso molecular:268.65BMS-191095
CAS:<p>BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.</p>Fórmula:C22H21ClN4O2Pureza:>99.99%Forma y color:SolidPeso molecular:408.88NS5806
CAS:<p>NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).</p>Fórmula:C16H8Br2F6N6OPureza:97.95%Forma y color:SolidPeso molecular:574.07Methocarbamol
CAS:<p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>Fórmula:C11H15NO5Pureza:99.96%Forma y color:Crystals From Benzene SolidPeso molecular:241.24Meticrane
CAS:<p>Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.</p>Fórmula:C10H13NO4S2Pureza:99.16%Forma y color:SolidPeso molecular:275.34Fluxametamide
CAS:<p>Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).</p>Fórmula:C20H16Cl2F3N3O3Pureza:99.49%Forma y color:SolidPeso molecular:474.26γ-Aminobutyric acid
CAS:<p>γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.</p>Fórmula:C4H9NO2Pureza:99.95%Forma y color:White Or Almost White(According To Quality Test Specification It Can Be White Or Almost White ) Solid PowderPeso molecular:103.12GABAA receptor agent 1
CAS:<p>GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.</p>Fórmula:C13H8ClN3O2Pureza:99.31%Forma y color:SolidPeso molecular:273.67Penicillin G sodium salt
CAS:<p>Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a</p>Fórmula:C16H17N2NaO4SPureza:98.11%Forma y color:White To Off-White Crystalline PowderPeso molecular:356.37NS19504
CAS:<p>NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.</p>Fórmula:C10H9BrN2SPureza:99.87%Forma y color:SolidPeso molecular:269.16Isoguvacine hydrochloride
CAS:<p>Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist.</p>Fórmula:C6H10ClNO2Pureza:99.59%Forma y color:SolidPeso molecular:163.6Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Fórmula:C14H24N2O3Pureza:99.16% - >99.99%Forma y color:White To Yellow Solid Solid Particulate/PowderPeso molecular:268.35Dooku1
CAS:<p>Dooku1, Yoda1 analog, blocks Piezo1 channels, halting Ca2+ entry. IC50: 1.3μM in HEK 293, 1.5μM in HUVEC, stops Yoda1's aortic relaxation.</p>Fórmula:C13H9Cl2N3OSPureza:98.87% - 99.74%Forma y color:SolidPeso molecular:326.2Tocainide hydrochloride
CAS:<p>Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.</p>Fórmula:C11H17ClN2OPureza:97%Forma y color:SolidPeso molecular:228.72Diphenidol hydrochloride
CAS:<p>Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.</p>Fórmula:C21H28ClNOPureza:99.15% - 99.33%Forma y color:Crystals Soluble In Methanol WaterPeso molecular:345.91Glipizide
CAS:<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Fórmula:C21H27N5O4SPureza:99.67% - 99.75%Forma y color:SolidPeso molecular:445.54Manidipine dihydrochloride
CAS:<p>Manidipine dihydrochloride (Manidipine 2HCl) is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).</p>Fórmula:C35H40Cl2N4O6Pureza:99.76% - 99.86%Forma y color:SolidPeso molecular:683.62NMDA-IN-1
CAS:<p>NMDA-IN-1 is a potent and NR2B-selective antagonist of NMDA(NMDA Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM).</p>Fórmula:C20H23ClFN3OPureza:99.57%Forma y color:SolidPeso molecular:375.87CIQ
CAS:<p>CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.</p>Fórmula:C26H26ClNO5Pureza:99.5%Forma y color:SolidPeso molecular:467.94Prilocaine hydrochloride
CAS:<p>Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.</p>Fórmula:C13H21ClN2OPureza:99.97%Forma y color:Needles White Or Off White Crystalline PowderPeso molecular:256.77EN6
CAS:<p>EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.</p>Fórmula:C19H14F2N4O2Pureza:95.74% - 97.04%Forma y color:SolidPeso molecular:368.34Bupivacaine hydrochloride
CAS:<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Fórmula:C18H28N2O·HClPureza:99.9% - >99.99%Forma y color:SolidPeso molecular:324.89DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Fórmula:C22H28Cl2O4Pureza:99.79% - 99.87%Forma y color:SolidPeso molecular:427.36Bemegride
CAS:<p>Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.</p>Fórmula:C8H13NO2Pureza:99.89%Forma y color:Physical Description White Crystalline Solid Sublimes At 212°F And 200 Mm Pressure (Ntp 1992)Peso molecular:155.19IK1 inhibitor PA-6
CAS:<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Fórmula:C31H32N4O2Pureza:98.9%Forma y color:SolidPeso molecular:492.61Clomethiazole
CAS:<p>Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It has potential for treating convulsive status epilepticus.</p>Fórmula:C6H8ClNSPureza:99.06%Forma y color:SolidPeso molecular:161.65Celivarone
CAS:<p>Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.</p>Fórmula:C34H47NO4Pureza:99.53%Forma y color:SolidPeso molecular:533.74Lotilaner
CAS:<p>Lotilaner is a parasiticide.</p>Fórmula:C20H14Cl3F6N3O3SPureza:99.56%Forma y color:SolidPeso molecular:596.76Trichlormethiazide
CAS:<p>Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics.</p>Fórmula:C8H8Cl3N3O4S2Pureza:98.8% - 99.54%Forma y color:SolidPeso molecular:380.66Miconazole
CAS:<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Fórmula:C18H14Cl4N2OPureza:98% - >99.99%Forma y color:SolidPeso molecular:416.13Elexacaftor
CAS:<p>Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.</p>Fórmula:C26H34F3N7O4SPureza:98.87% - 99.87%Forma y color:SolidPeso molecular:597.65Omeprazole
CAS:<p>Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.</p>Fórmula:C17H19N3O3SPureza:98.43% - 98.48%Forma y color:White SolidPeso molecular:345.42Phenazopyridine hydrochloride
CAS:<p>Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.</p>Fórmula:C11H12ClN5Pureza:99.27%Forma y color:Brownish-Yellow Crystals Aqueous Solutions Are Yellow To Brick-Red And Slightly Acidic; They May Be Stabilized By The AdditionPeso molecular:249.7GFB-8438
CAS:<p>GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).</p>Fórmula:C16H14ClF3N4O2Pureza:99.58%Forma y color:SolidPeso molecular:386.76Eact
CAS:<p>Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.</p>Fórmula:C22H24N2O5SPureza:98.14%Forma y color:SolidPeso molecular:428.5
