Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(52 productos)
- Canal de calcio(496 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(337 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(277 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2293 productos de "Transportador de membrana / canal de iones"
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CGP 39551
CAS:<p>CGP 39551 is a NMDA antagonist.</p>Fórmula:C8H16NO5PPureza:98%Forma y color:White SolidPeso molecular:237.19bis(7)-Tacrine
CAS:<p>Bis(7)-tacrine dihydrochloride: dimeric AChE inhibitor; may treat Alzheimer's; blocks NMDA, antagonizes GABA A.</p>Fórmula:C33H42Cl2N4Forma y color:SolidPeso molecular:565.63AS1928370
CAS:<p>AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1).</p>Fórmula:C29H31N3O2Forma y color:SolidPeso molecular:453.58NAB-14
CAS:<p>NAB-14: non-competitive GluN2C/D antagonist, IC50 580 nM for GluN1/2D, >800x selectivity over GluN2A/B, blood-brain-barrier penetrant.</p>Fórmula:C20H21N3O3Forma y color:SolidPeso molecular:351.4Ac32Az19
CAS:<p>Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed</p>Fórmula:C37H33N3O6Forma y color:SolidPeso molecular:615.67GABAA receptor agent 7
CAS:<p>Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.</p>Fórmula:C18H13ClN4OForma y color:SolidPeso molecular:336.77ZK93423
CAS:<p>ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.</p>Fórmula:C23H22N2O4Forma y color:SolidPeso molecular:390.43AMG-1
CAS:<p>AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.</p>Fórmula:C18H9ClF5N3OForma y color:SolidPeso molecular:413.73Efflux inhibitor-1
CAS:<p>Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor.</p>Fórmula:C28H25N5O3Forma y color:SolidPeso molecular:479.53(Rac)-NMDAR antagonist 1
CAS:<p>(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.</p>Fórmula:C20H20BrN3O2Forma y color:SolidPeso molecular:414.3P-gp inhibitor 3
<p>P-gp inhibitor 3 boosts Paclitaxel's effect by strongly reversing MDR via P-gp efflux blockade.</p>Fórmula:C48H67N3O6Forma y color:SolidPeso molecular:782.06Clobutinol
CAS:<p>Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].</p>Fórmula:C14H22ClNOForma y color:SolidPeso molecular:255.78(R)-Posenacaftor sodium
CAS:<p>(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.</p>Fórmula:C27H27NNaO5Forma y color:SolidPeso molecular:468.505P-CAB agent 2 hydrochloride
CAS:<p>P-CAB agent 2 hydrochloride is a strong oral gastric acid secretion inhibitor with IC50 <100 nM on H+/K+ ATPase and 18.69 µM on hERG channel, non-toxic.</p>Fórmula:C22H26ClFN2O4SForma y color:SolidPeso molecular:468.97SK3 Channel-IN-1
CAS:<p>SK3 Channel-IN-1: Potent, selective SK3 modulator; inhibits MDA-MB-435 migration, low cytotoxicity.</p>Fórmula:C25H49NOForma y color:SolidPeso molecular:379.66Xininurad
CAS:<p>Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.</p>Fórmula:C15H10Br2FN3O2Forma y color:SolidPeso molecular:443.07MRS-1477
CAS:<p>MRS-1477 is used as a TRPV1 positive allosteric modulator (PAM).</p>Fórmula:C21H27NO4SPureza:98%Forma y color:SolidPeso molecular:389.51Cgp 31358
CAS:<p>CGP 31358 is a new chemical that targets the NMDA receptor, potentially aiding in molecular pharmacology research.</p>Fórmula:C19H19ClN4O2Forma y color:SolidPeso molecular:370.83(1R,2R)-ML-SI3
CAS:<p>(1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases.</p>Fórmula:C23H31N3O3SForma y color:SolidPeso molecular:429.58GLPG-3221
CAS:<p>GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.</p>Fórmula:C30H37F3N2O6Pureza:98%Forma y color:SolidPeso molecular:578.62IDO1-IN-19
CAS:<p>IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.</p>Fórmula:C25H22F4N2O3Forma y color:SolidPeso molecular:474.45P2X7 receptor antagonist-3
CAS:<p>P2X7 receptor antagonist-3 is a powerful inhibitor of the P2X7 receptor, exhibiting IC50 values of 4.2 nM in humans and 6.8 nM in rats, indicating its high</p>Fórmula:C17H12ClF3N6OForma y color:SolidPeso molecular:408.77FFN200 dihydrochloride
CAS:<p>FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue.</p>Fórmula:C11H14Cl2N2O2Forma y color:SolidPeso molecular:277.15Ivabradine
CAS:<p>Ivabradine: oral HCN blocker, lowers heart rate without affecting blood pressure, has anticonvulsant and anti-anginal properties.</p>Fórmula:C27H36N2O5Forma y color:SolidPeso molecular:468.59SN40
CAS:<p>SN40: AAT inhibitor for cancer research; inhibits hASCT1 (7.29 μM), rASCT2 (2.42 μM), hASCT2 (2.94 μM), EAAT1/EAAC1/EAAT5 (5.55 μM), EAAT2 (24.43 μM).</p>Fórmula:C18H20N2O2Forma y color:SolidPeso molecular:296.36Cl-HIBO
CAS:<p>desensitising AMPA receptor agonist</p>Fórmula:C6H7ClN2O4Pureza:98%Forma y color:SolidPeso molecular:206.58NHE3-IN-2
CAS:<p>NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.</p>Fórmula:C15H12ClN5Forma y color:SolidPeso molecular:297.74Irampanel
CAS:<p>Irampanel is a neuroprotectant and anticonvulsant.</p>Fórmula:C18H19N3O2Forma y color:SolidPeso molecular:309.36GYKI 52466 HCl
CAS:<p>GYKI 52466 is an AMPA antagonist with IC50 of 7.5 µM, also blocking kainate currents (IC50 11 µM) and reduces EPSCs and seizures in rats.</p>Fórmula:C17H16ClN3O2Forma y color:SolidPeso molecular:329.784Nemadipine-A
CAS:<p>Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.</p>Fórmula:C19H18F5NO4Forma y color:SolidPeso molecular:419.34KR 60436
CAS:<p>KR 60436 is an inhibitor of potassium hydrogen ATPase.</p>Fórmula:C22H22F3N3O3Forma y color:SolidPeso molecular:433.42Zoniporide dihydrochloride
CAS:<p>Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor</p>Fórmula:C17H18Cl2N6OPureza:98%Forma y color:SolidPeso molecular:393.27(R)-Olacaftor
CAS:<p>(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.</p>Fórmula:C29H34FN3O4SForma y color:SolidPeso molecular:539.66A1899
CAS:<p>A1899 is a effective and selective TASK-1 and TASK-3 antagonist.</p>Fórmula:C30H26F2N2O3Pureza:98%Forma y color:SolidPeso molecular:500.54JNJ-54166060
CAS:<p>JNJ-54166060 is a potent and selective antagonist of P2X7 receptor, with IC 50 s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively [1].</p>Fórmula:C20H15ClF4N4OForma y color:SolidPeso molecular:438.81L-AP5
CAS:<p>L-AP5 is a NMDA antagonist.</p>Fórmula:C5H12NO5PPureza:98%Forma y color:SolidPeso molecular:197.13UMB68 sodium
CAS:<p>UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.</p>Fórmula:C6H12NaO3Forma y color:SolidPeso molecular:155.149Cgp 55802A
CAS:<p>CGP 55802A is a novel photoaffinity ligand for in-situ labeling of NMDA receptors.</p>Fórmula:C18H24IN5NaO7PForma y color:SolidPeso molecular:603.286PPPA
CAS:<p>PPPA is a NMDA receptor antagonist.</p>Fórmula:C9H18NO5PPureza:98%Forma y color:SolidPeso molecular:251.22PA1 2HCl
CAS:<p>PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC).</p>Fórmula:C18H16ClN9OForma y color:SolidPeso molecular:409.83Lercanidipine. (R)-
CAS:<p>(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.</p>Fórmula:C36H41N3O6Forma y color:SolidPeso molecular:611.73OptoBI-1
CAS:<p>OptoBI-1 是一种光敏分子，是光致变色的TRPC3激动剂，可用作控制神经元放电的光药理学工具。</p>Fórmula:C32H37N5O2Forma y color:SoildPeso molecular:523.674,9-Anhydrotetrodotoxin
CAS:<p>4,9-anhydro-TTX blocks Nav1.6 channels (IC50=7.8 nM); has varying IC50 for Nav1.2-Nav1.8.</p>Fórmula:C11H15N3O7Forma y color:SolidPeso molecular:301.25RA-2
CAS:<p>RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries.</p>Fórmula:C22H16F2O6Forma y color:SolidPeso molecular:414.36Procyclidine
CAS:<p>Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.</p>Fórmula:C19H29NOForma y color:SolidPeso molecular:287.44TMB 8 (hydrochloride)
CAS:<p>TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.</p>Fórmula:C22H38ClNO5Forma y color:White SolidPeso molecular:431.99Etbicyphat
CAS:<p>Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.</p>Fórmula:C6H11O4PForma y color:SolidPeso molecular:178.12CGP-78608
CAS:<p>CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.</p>Fórmula:C11H13BrN3O5PForma y color:SolidPeso molecular:378.12TTT-28
CAS:<p>TTT-28, a thiazole-valine peptidomimetic, selectively inhibits ABCB1 to reverse MDR with low toxicity.</p>Fórmula:C31H31N3O6SPureza:98%Forma y color:SolidPeso molecular:573.66Radequinil
CAS:<p>Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).</p>Fórmula:C18H14N4O3Pureza:98%Forma y color:SolidPeso molecular:334.33
