Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(52 productos)
- Canal de calcio(496 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(337 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(277 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2293 productos de "Transportador de membrana / canal de iones"
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Lanicemine
CAS:<p>Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1 μM).</p>Fórmula:C13H14N2Pureza:98%Forma y color:SolidPeso molecular:198.26P2X2/3 modulator-1
CAS:<p>Compound 46, a P2X2/3 modulator, could aid in research of pain, CNS disorders, and inflammation.</p>Fórmula:C26H21N5OForma y color:SolidPeso molecular:419.48UTA1inh-C1
CAS:<p>UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.</p>Fórmula:C22H24N6O4S2Forma y color:SolidPeso molecular:500.59TRPC6-IN-3
CAS:<p>TRPC6-IN-3 is an oral TRPC6 ion channel inhibitor, regulating calcium levels and membrane potential.</p>Fórmula:C22H22FN5O3Forma y color:SolidPeso molecular:423.44KR-30450
CAS:<p>KR-30450, a potassium channel agonist, is used potentially for the treatment of hypertension.</p>Fórmula:C17H18N2O6Forma y color:SolidPeso molecular:346.33Taquidil
CAS:<p>Tocainide hydrochloride: oral antiarrhythmic, sodium channel blocker, akin to lidocaine.</p>Fórmula:C11H17ClN2OForma y color:SolidPeso molecular:228.718P-gp inhibitor 4
CAS:<p>P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM.</p>Fórmula:C38H38N2O8S2Forma y color:SolidPeso molecular:714.85NMDA-IN-2
CAS:<p>NMDA-IN-2 (compound 6b) is a Procaine derivative that is an inhibitor of NMDA receptor 2B subtype [1].</p>Fórmula:C15H22N2O3Forma y color:SolidPeso molecular:278.35PD-307243
CAS:<p>PD-307243 is an activator of hERG channel.</p>Fórmula:C20H15Cl2N3O2Forma y color:SolidPeso molecular:400.26RQ-00311651
CAS:<p>RQ-00311651 is a novel T-type Ca2+ channel blocker. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.</p>Fórmula:C19H18F3N5O2Forma y color:SolidPeso molecular:405.37DDO-02005
CAS:<p>DDO-02005, a Kv1.5 inhibitor (IC50: 0.72 μM), counters fibrillation and arrhythmias in rats.</p>Fórmula:C21H27Cl2N3O2Forma y color:SolidPeso molecular:424.37(±)-C3001a
CAS:<p>(RS)-C3001a is the racemic mixture of C3001a (CAS: 2415154-29-7). C3001a is a selective activator of the TREK channel.</p>Fórmula:C21H20N2O3SPureza:99.13%Forma y color:SolidPeso molecular:380.46TRPC3/6-IN-1
CAS:<p>TRPC3/6-IN-1 selectively inhibits hTRPC3/6 with IC50 of 1260/500 nM, useful in heart failure research.</p>Fórmula:C20H19N3O2SForma y color:SolidPeso molecular:365.45Ivacaftor-D9
CAS:<p>CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.</p>Fórmula:C24H19D9N2O3Forma y color:SolidPeso molecular:401.55RG100204
CAS:<p>RG100204 is an orally active AQP9 inhibitor with anti-inflammatory properties. It alleviates cardiac dysfunction (systolic and diastolic) induced by sepsis, improves renal dysfunction, and reduces the elevation of the cellular damage marker LDH.</p>Fórmula:C20H26N6O2S2Forma y color:SolidPeso molecular:446.59P-gp inhibitor 17
CAS:<p>P-gp Inhibitor 17 (compound 2g), a potent inhibitor, directly interacts with the transmembrane domain of P-gp. This compound is useful for studying P-gp-mediated multidrug resistance in tumor cells [1].</p>Fórmula:C36H49N3O3Forma y color:SolidPeso molecular:571.79CW0134
CAS:<p>CW0134 (Compound 12) serves as a modulator for exportin1 (XPO1), disrupting chromatin binding and inhibiting NFAT transcription factors and T cell activation [1].</p>Fórmula:C11H7ClF3N3O2Forma y color:SolidPeso molecular:305.64DPI 201-106
CAS:<p>DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.</p>Fórmula:C29H30N4O2Pureza:99.94%Forma y color:SolidPeso molecular:466.57(+)-Nipecotic acid
CAS:<p>(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors.</p>Fórmula:C6H11NO2Pureza:99.38%Forma y color:SolidPeso molecular:129.16Anxiolytic/nonsedative agent-1
CAS:<p>TCS 1205: Selective GABAA agonist, BzR affinity in bovine brain (Kis: 14-239 nM), α2 efficacy in vitro, anxioselective in vivo.</p>Fórmula:C18H15N3O4Pureza:98.61%Forma y color:SolidPeso molecular:337.33(S)-SNAP5114
CAS:<p>(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.</p>Fórmula:C30H35NO6Pureza:97%Forma y color:SolidPeso molecular:505.6Psora 4
CAS:<p>Psora 4 (5-(4-Phenylbutoxy)psoralen) is a Kv1.3 blocker and a caloric restriction mimetic.</p>Fórmula:C21H18O4Forma y color:SolidPeso molecular:334.373α,21-Dihydroxy-5α-pregnan-20-one
CAS:<p>3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.</p>Fórmula:C21H34O3Pureza:98.00%Forma y color:SolidPeso molecular:334.49AVE-0118
CAS:<p>AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.</p>Fórmula:C30H29N3O3Pureza:97.04% - 98.93%Forma y color:SolidPeso molecular:479.57L589-420
CAS:<p>L589-420 is a sodium pump inhibitor in human erythrocytes.</p>Fórmula:C14H14Cl2O4Pureza:98%Forma y color:SolidPeso molecular:317.16YM928
CAS:<p>YM928 is an orally active antagonist of the AMPA receptor.</p>Fórmula:C14H10ClN3OSPureza:98%Forma y color:SolidPeso molecular:303.77CCMQ
CAS:inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sitesFórmula:C12H9NO4Pureza:98%Forma y color:SolidPeso molecular:231.2Bms 188107
CAS:<p>Bms 188107 is a calcium antagonist, it has cardioprotective effects.</p>Fórmula:C25H26N2O4Pureza:98%Forma y color:SolidPeso molecular:418.48Caramiphen
CAS:<p>Caramiphen is an antimuscarinic and anticholinergic agent that acts as an antagonist of the NMDA receptor.</p>Fórmula:C18H27NO2Pureza:98%Forma y color:SolidPeso molecular:289.41Viquidil
CAS:<p>Viquidil is an agent with the activity of a vasodilator.</p>Fórmula:C20H24N2O2Pureza:98%Forma y color:SolidPeso molecular:324.42(R)-Licarbazepine Acetate
CAS:<p>(R)-Licarbazepine Acetate is a hopeful antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.</p>Fórmula:C17H16N2O3Forma y color:SolidPeso molecular:296.32COR628
CAS:<p>COR628 is the GABA(B) receptor positive allosteric modulator.</p>Fórmula:C16H23NO3SForma y color:SolidPeso molecular:309.42AZD 2066
CAS:<p>AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.</p>Fórmula:C19H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:381.82BBR 2160
CAS:<p>BBR 2160: a calcium-antagonist dihydropyridine derivative, reduces heart tissue contractility and shortens action potentials.</p>Fórmula:C21H25N3O7SForma y color:SolidPeso molecular:463.5LY-395153
CAS:<p>LY-395153 is a novel potentiator of AMPA receptor.</p>Fórmula:C19H24N2O3SForma y color:SolidPeso molecular:360.47Tolperisone free base
CAS:Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm.Fórmula:C16H23NOPureza:98%Forma y color:SolidPeso molecular:245.36Lercanidipine, (S)-
CAS:(S)-Lercanidipine: a dihydropyridine calcium blocker with prolonged antihypertensive and kidney-protective properties.Fórmula:C36H41N3O6Pureza:98%Forma y color:SolidPeso molecular:611.73Ensaculin HCl
CAS:<p>Ensaculin: NMDA antagonist, 5HT1A agonist, may treat Alzheimer's, enhances memory, neuroprotective, binds multiple receptors.</p>Fórmula:C26H33ClN2O5Pureza:98%Forma y color:SolidPeso molecular:489Naftazone
CAS:<p>Naftazone: vasoprotectant for hemostasis; boosts vein cell growth in vitro without affecting clotting.</p>Fórmula:C11H9N3O2Pureza:98%Forma y color:SolidPeso molecular:215.21Tiropramide
CAS:<p>Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS.</p>Fórmula:C28H41N3O3Pureza:98%Forma y color:SolidPeso molecular:467.64Riodipine
CAS:Riodipine, a calcium channel blocker, is used as cardiovascular drugs.Fórmula:C18H19F2NO5Pureza:98%Forma y color:SolidPeso molecular:367.34DS28120313
CAS:DS28120313 is an oral inhibitor of hepcidin production (IC50: 0.093 μM).Fórmula:C16H17N5O2Forma y color:SolidPeso molecular:311.34CPP-115
CAS:<p>CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.</p>Fórmula:C7H9F2NO2Forma y color:SolidPeso molecular:177.15Ethopropazine Hydrochloride
CAS:<p>Ethopropazine Hydrochloride is the salt form of Profenamine，anticholinergic, antihistamine, and anti-adrenergic，Parkinson's disease,an AChE inhibitor</p>Fórmula:C19H25ClN2SPureza:98.25%Forma y color:SolidPeso molecular:348.93DHP-218
CAS:<p>DHP-218, a calcium channel blocker, inhibits rat aorta contractions; pA2: 9.11, IC50: 6.3 nmol/L (high K+) & 66 nmol/L (phenylephrine).</p>Fórmula:C18H21N2O7PPureza:98%Forma y color:SolidPeso molecular:408.34BCTP
CAS:<p>BCTP is a polymodal inhibitor of TRPV1. It has a reduced liability for hyperthermia.</p>Fórmula:C17H16ClN3OSPureza:98%Forma y color:SolidPeso molecular:345.85Chlormethiazole edisylate
CAS:<p>Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.</p>Fórmula:C8H14ClNO6S3Pureza:98%Forma y color:SolidPeso molecular:351.85Talopram hydrochloride
CAS:<p>noradrenalin transporter (NET) inhibitor</p>Fórmula:C20H26ClNOPureza:98%Forma y color:SolidPeso molecular:331.88IAA-94
CAS:<p>IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.</p>Fórmula:C17H18Cl2O4Forma y color:SolidPeso molecular:357.23A 39355
CAS:<p>A 39355 may specifically overcome multidrug resistance without the serious hypotensive effects associated with calcium antagonists.</p>Fórmula:C28H39Cl2N3OPureza:98%Forma y color:SolidPeso molecular:504.54
