Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2277 productos de "Transportador de membrana / canal de iones"
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ABCG2-IN-2
CAS:<p>ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug</p>Fórmula:C25H34N4O4Pureza:98%Forma y color:SolidPeso molecular:454.56U-89843A
CAS:<p>U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].</p>Fórmula:C16H24ClN5Pureza:98%Forma y color:SolidPeso molecular:321.85TWIK-1/TREK-1-IN-1
CAS:<p>Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and</p>Fórmula:C21H24F3NO3Pureza:98%Forma y color:SolidPeso molecular:395.42D-3263 hydrochloride
CAS:<p>D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.</p>Fórmula:C21H32ClN3O3Pureza:99.93%Forma y color:SolidPeso molecular:409.95Vernakalant Hydrochloride
CAS:<p>Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.</p>Fórmula:C20H32ClNO4Pureza:99.89%Forma y color:SolidPeso molecular:385.93YHO-13351 free base
CAS:<p>YHO-13351 free base is the water-soluble prodrug of YHO-13177 which is an inhibitor of BCRP .</p>Fórmula:C26H33N3O4SPureza:99.89%Forma y color:SolidPeso molecular:483.62Pinacidil
CAS:<p>Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and</p>Fórmula:C13H19N5Pureza:99.9%Forma y color:SolidPeso molecular:245.32TRPV4 agonist-1
CAS:<p>TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).</p>Fórmula:C25H23ClF2N4O2Pureza:98%Forma y color:SolidPeso molecular:484.93PF 05089771 tosylate
CAS:<p>PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.</p>Fórmula:C18H12Cl2FN5O3S2·C7H8O3SPureza:98.55%Forma y color:SolidPeso molecular:672.56Lesogaberan
CAS:<p>Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).</p>Fórmula:C3H9FNO2PPureza:98%Forma y color:SolidPeso molecular:141.08UK 78282 hydrochloride
CAS:<p>UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.</p>Fórmula:C29H36ClNO2Pureza:99.68%Forma y color:SolidPeso molecular:466.05Puliginurad
CAS:<p>Puliginurad (YL-90148) is a urate transporter protein inhibitor that inhibits the reabsorption of uric acid.Puliginurad is used in the treatment of gout.</p>Fórmula:C19H16N2O2SPureza:99.96% - 99.96%Forma y color:SolidPeso molecular:336.41GX-674
CAS:<p>GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of</p>Fórmula:C21H13ClF2N6O3S2Pureza:98.60%Forma y color:SolidPeso molecular:534.95TRAM 39
CAS:<p>TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.</p>Fórmula:C20H14ClNPureza:99.97%Forma y color:SolidPeso molecular:303.78Tracazolate hydrochloride
CAS:<p>Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.</p>Fórmula:C16H25ClN4O2Pureza:99.52%Forma y color:SolidPeso molecular:340.85TRPM4-IN-2
CAS:<p>NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.</p>Fórmula:C19H14ClNO4Pureza:99.21%Forma y color:SolidPeso molecular:355.77RO 4938581
CAS:<p>RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).</p>Fórmula:C13H8BrF2N5Pureza:98%Forma y color:SolidPeso molecular:352.14JYL 1421
CAS:<p>JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).</p>Fórmula:C20H26FN3O2S2Pureza:98.83%Forma y color:SolidPeso molecular:423.57GDC-0276
CAS:<p>GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.</p>Fórmula:C24H31FN2O4SPureza:99.77%Forma y color:SolidPeso molecular:462.58RY796
CAS:<p>RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders.</p>Fórmula:C21H27N3O2Pureza:98.59%Forma y color:SolidPeso molecular:353.46RN9893
CAS:<p>RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.</p>Fórmula:C21H23F3N4O5SPureza:99.89%Forma y color:SolidPeso molecular:500.49ATX-II TFA
<p>ATX-II TFA, a specific Na+ channel modulator toxin, is derived from the venom of the sea anemone (Anemonia sulcata).</p>Pureza:98%Forma y color:Odour SolidAZD 3043
CAS:<p>AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.</p>Fórmula:C19H29NO5Pureza:98.19% - 99.55%Forma y color:SolidPeso molecular:351.44E 0747
CAS:<p>E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.</p>Fórmula:C21H28ClN3O4Pureza:95.17%Forma y color:SolidPeso molecular:421.92TRPV3 antagonist 74a
CAS:<p>TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.</p>Fórmula:C17H17F3N2O2Pureza:≥98.0%Forma y color:SolidPeso molecular:338.32AVE1231
CAS:<p>AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.</p>Fórmula:C20H27N3O4SPureza:98.03%Forma y color:SolidPeso molecular:405.51Phaclofen
CAS:<p>GABAB antagonist</p>Fórmula:C9H13ClNO3PPureza:99.32%Forma y color:White SolidPeso molecular:249.63GAL-021 sulfate
CAS:<p>GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.</p>Fórmula:C11H24N6O5SPureza:99.92%Forma y color:SolidPeso molecular:352.41Istaroxime hydrochloride
CAS:<p>Istaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and SERCA 2 activator, and is a novel positive inotropic compound.</p>Fórmula:C21H33ClN2O3Forma y color:SolidPeso molecular:396.95GX-585
CAS:<p>GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.</p>Fórmula:C24H25Cl2FN4O3SPureza:99.02% - 99.03%Forma y color:SolidPeso molecular:539.45SRI-37240
CAS:<p>SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.</p>Fórmula:C24H23N3O2Pureza:98.73%Forma y color:SolidPeso molecular:385.46Aprikalim
CAS:<p>Aprikalim opens KATP channels, protects the heart, and at high doses, dilates blood vessels.</p>Fórmula:C12H16N2OS2Pureza:99.42% - 99.90%Forma y color:SolidPeso molecular:268.4Suriclone
CAS:<p>Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.</p>Fórmula:C20H20ClN5O3S2Pureza:99.21% - 99.73%Forma y color:SolidPeso molecular:477.99KT-362 fumarate
CAS:<p>KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.</p>Fórmula:C26H32N2O7SPureza:99.75% - 99.98%Forma y color:SolidPeso molecular:516.61AGN-201904
CAS:AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers.Fórmula:C25H25N3O8S2Pureza:97.32%Forma y color:SolidPeso molecular:559.61DMT1 blocker 1
CAS:<p>DMT1 blocker 1 inhibits DMT1; IC50=0.64μM; may prevent intestinal iron absorption.</p>Fórmula:C16H14N4O2Pureza:99.73%Forma y color:SolidPeso molecular:294.31Trombodipine
CAS:<p>Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.</p>Fórmula:C21H24N2O7SPureza:98.73% - 99.14%Forma y color:SolidPeso molecular:448.49Elismetrep
CAS:<p>Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.</p>Fórmula:C27H21F3N2O5SPureza:99.37% - 99.93%Forma y color:SolidPeso molecular:542.53R 56865
CAS:<p>R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.</p>Fórmula:C23H28FN3OSPureza:99.52%Forma y color:SolidPeso molecular:413.55Riluzole hydrochloride
CAS:<p>Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).</p>Fórmula:C8H6ClF3N2OSPureza:99.76%Forma y color:SolidPeso molecular:270.66SKF96067
CAS:<p>SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.</p>Fórmula:C21H22N2O2Pureza:99.89%Forma y color:SolidPeso molecular:334.41Losigamone
CAS:<p>Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.</p>Fórmula:C12H11ClO4Pureza:99.98%Forma y color:SolidPeso molecular:254.67TASK-1-IN-1
CAS:<p>TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.</p>Fórmula:C22H20N2O2Pureza:99.57%Forma y color:SoildPeso molecular:344.41Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Fórmula:C18H19N3O2Pureza:97.07%Forma y color:SolidPeso molecular:309.36Fengabine
CAS:<p>Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.</p>Fórmula:C17H17Cl2NOPureza:99%Forma y color:SolidPeso molecular:322.23TAK-653
CAS:<p>TAK-653 is a selective AMPA receptor PAM with minimal agonist activity, showing antidepressant-like effects and safety in rats.</p>Fórmula:C19H23N3O3SPureza:99.89%Forma y color:SolidPeso molecular:373.47Neboglamine hydrochloride
CAS:<p>Neboglamine (CR-2249, XY-2401) hydrochloride boosts NMDA receptor, aids schizophrenia research, and is orally active.</p>Fórmula:C13H25ClN2O3Pureza:99.19%Forma y color:SolidPeso molecular:292.8DSP-0565
CAS:<p>DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.</p>Fórmula:C14H12FNOPureza:99.51% - 99.56%Forma y color:SolidPeso molecular:229.25Alpidem
CAS:<p>Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.</p>Fórmula:C21H23Cl2N3OPureza:99.56% - 99.97%Forma y color:White To Off-White SolidPeso molecular:404.33Muscimol HBr
CAS:<p>Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.</p>Fórmula:C4H7BrN2O2Pureza:98.13%Forma y color:Off-White PowderPeso molecular:195.01
