Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2275 productos de "Transportador de membrana / canal de iones"
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PD-118057
CAS:<p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>Fórmula:C21H17Cl2NO2Pureza:99.16% - 99.97%Forma y color:SolidPeso molecular:386.27TASK-1-IN-1
CAS:<p>TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.</p>Fórmula:C22H20N2O2Pureza:99.57%Forma y color:SoildPeso molecular:344.41GW 542573X
CAS:<p>GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve</p>Fórmula:C19H28N2O5Pureza:99.91%Forma y color:SolidPeso molecular:364.44(+)-KCC2 blocker 1
CAS:<p>(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).</p>Fórmula:C22H25NO5SPureza:99.88%Forma y color:SolidPeso molecular:415.5Cerebrocrast
CAS:<p>Cerebrocrast (IOS-11212) has anti-inflammatory and hypoglycemic activity, blocks human platelet activation, and is used in the study of diabetes.</p>Fórmula:C26H35F2NO7Pureza:99.71%Forma y color:SolidPeso molecular:511.56Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Fórmula:C18H19N3O2Pureza:97.07%Forma y color:SolidPeso molecular:309.36SCH28080
CAS:<p>SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent</p>Fórmula:C17H15N3OPureza:99.24%Forma y color:SolidPeso molecular:277.32SKA-111
CAS:<p>SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.</p>Fórmula:C12H10N2SPureza:99.9%Forma y color:SolidPeso molecular:214.29PG01
CAS:<p>PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.</p>Fórmula:C28H29N3O2Pureza:99.87%Forma y color:SolidPeso molecular:439.55Saviprazole
CAS:<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Fórmula:C15H10F7N3O2S2Pureza:97.07% - 97.17%Forma y color:SolidPeso molecular:461.38SET 2
CAS:<p>SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.</p>Fórmula:C17H21F3N4O2SPureza:99.77%Forma y color:SolidPeso molecular:402.43Muscimol HBr
CAS:<p>Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.</p>Fórmula:C4H7BrN2O2Pureza:98.13%Forma y color:Off-White PowderPeso molecular:195.01MK-0448
CAS:<p>MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.</p>Fórmula:C24H21FN4O2SPureza:99.25% - 99.79%Forma y color:SolidPeso molecular:448.51RWJ-51204
CAS:<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Forma y color:SolidPeso molecular:399.39Fengabine
CAS:<p>Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.</p>Fórmula:C17H17Cl2NOPureza:99%Forma y color:SolidPeso molecular:322.23HC-070
CAS:<p>HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).</p>Fórmula:C22H20Cl2N4O4Pureza:98.48%Forma y color:SolidPeso molecular:475.32Abeprazan hydrochloride
CAS:<p>Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase</p>Fórmula:C19H18ClF3N2O3SPureza:98.57%Forma y color:SolidPeso molecular:446.87RL648_81
CAS:<p>RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.</p>Fórmula:C17H17F4N3O2Pureza:99.82%Forma y color:SolidPeso molecular:371.33Sarmazenil
CAS:<p>Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.</p>Fórmula:C15H14ClN3O3Pureza:99.46%Forma y color:SolidPeso molecular:319.74Pyr3
CAS:<p>Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.</p>Fórmula:C16H11Cl3F3N3O3Pureza:98.04%Forma y color:SolidPeso molecular:456.63Losigamone
CAS:<p>Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.</p>Fórmula:C12H11ClO4Pureza:99.98%Forma y color:SolidPeso molecular:254.67Sulcardine sulfate
CAS:<p>Sulcardine sulfate (B-87823) is a multi-ion channel blocker with antiarrhythmic activity that inhibits Na+, K+, and Ca2+ channels.</p>Fórmula:C24H35N3O8S2Pureza:98.74%Forma y color:SolidPeso molecular:557.68FR-167356
CAS:<p>FR-167356 inhibits a3 isoform H⁺-ATPase (IC50: 170-370 nM), targeting osteoclasts, kidneys, macrophages; reduces B16-F10 bone metastasis.</p>Fórmula:C19H17Cl2NO3Pureza:98.44% - 99.74%Forma y color:SolidPeso molecular:378.25Ani9
CAS:<p>Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.</p>Fórmula:C17H17ClN2O3Pureza:99.73%Forma y color:SolidPeso molecular:332.78Trombodipine
CAS:<p>Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.</p>Fórmula:C21H24N2O7SPureza:98.73% - 99.14%Forma y color:SolidPeso molecular:448.49DFP00173
CAS:<p>DFP00173: Potent, selective AQP3 inhibitor; IC50 ~0.1-0.4 μM; less effective on AQP7, AQP9.</p>Fórmula:C11H7Cl2N3O3SPureza:99.53% - 99.53%Forma y color:SolidPeso molecular:332.16DMP-543
CAS:<p>DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.</p>Fórmula:C26H18F2N2OPureza:99.89%Forma y color:SolidPeso molecular:412.43Leminoprazole
CAS:<p>Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.</p>Fórmula:C19H23N3OSPureza:99.08% - 99.56%Forma y color:SolidPeso molecular:341.47UK 66914
CAS:<p>UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.</p>Fórmula:C18H24N4O3SPureza:99.75%Forma y color:SolidPeso molecular:376.47ZM 226600
CAS:<p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>Fórmula:C16H14F3NO4SPureza:99.87%Forma y color:SolidPeso molecular:373.35NNC 05-711
CAS:<p>NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.</p>Fórmula:C21H23ClN2O3Pureza:99.92%Forma y color:SolidPeso molecular:386.87Quinabactin
CAS:<p>Quinabactin (LC-66C6): ABA agonist, induces guard cell closure, reduces water loss, hinders germination, boosts drought resistance in Arabidopsis/soybean.</p>Fórmula:C20H24N2O3SPureza:99.63%Forma y color:SolidPeso molecular:372.48NaV1.2/1.6 channel blocker-1
CAS:<p>NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.</p>Fórmula:C14H14N2OSPureza:99.54%Forma y color:SolidPeso molecular:258.34XE991
CAS:<p>XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.</p>Fórmula:C26H20N2OPureza:98.87%Forma y color:SolidPeso molecular:376.45Silperisone HCl
CAS:<p>Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.</p>Fórmula:C15H25ClFNSiPureza:99.62%Forma y color:SolidPeso molecular:301.9Ru-32514
CAS:<p>Ru-32514 is a benzodiazepine receptor agonist.</p>Fórmula:C18H17N3O2Pureza:99.21%Forma y color:SolidPeso molecular:307.35TWIK-1/TREK-1-IN-3
CAS:<p>TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.</p>Fórmula:C19H27F3N2O2Pureza:99.04%Forma y color:SolidPeso molecular:372.43IKs124
CAS:<p>IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.</p>Fórmula:C18H26N2O3SPureza:99.53%Forma y color:SolidPeso molecular:350.48UCL 2077
CAS:<p>UCL 2077 blocks KCNQ channels, related to epilepsy, and selective slow-afterhyperpolarization channels, with 500 nM IC50, sparing Ca2+ channels.</p>Fórmula:C25H22N2Pureza:99.58%Forma y color:SolidPeso molecular:350.46Aptiganel
CAS:<p>Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke.</p>Fórmula:C20H21N3Pureza:98.13% - 98.90%Forma y color:SolidPeso molecular:303.4Cirsimaritin
CAS:<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Fórmula:C17H14O6Pureza:99.9%Forma y color:SolidPeso molecular:314.29YM758
CAS:<p>YM758 is an inhibitor of If current channel.</p>Fórmula:C26H32FN3O4Pureza:99.65%Forma y color:SolidPeso molecular:469.55Golexanolone
CAS:<p>Golexanolone can be used to study neurological diseases.</p>Fórmula:C21H31NO2Pureza:99.90% - 99.99%Forma y color:SolidPeso molecular:329.48BPDBA
CAS:<p>BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and</p>Fórmula:C19H20Cl2N2OPureza:99.37% - 99.95%Forma y color:SolidPeso molecular:363.28TC-I 2014
CAS:<p>TC-I 2014 shows antiallodynic properties in pain models.</p>Fórmula:C23H19F6N3OPureza:99.07%Forma y color:SolidPeso molecular:467.41R 56865
CAS:<p>R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.</p>Fórmula:C23H28FN3OSPureza:99.52%Forma y color:SolidPeso molecular:413.55Orphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Fórmula:C18H23NOPureza:98.91% - 99.11%Forma y color:SolidPeso molecular:269.38GSK 2833503A
CAS:<p>GSK 2833503A: potent TRPC6/3 antagonist; IC50: 3-16/21-100 nM; >63x selective; inhibits cardiac hypertrophy signaling.</p>Fórmula:C18H21ClFN3OSForma y color:SolidPeso molecular:381.9Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Fórmula:C21H26N4O2Pureza:99.54%Forma y color:SolidPeso molecular:366.46OADS
CAS:<p>OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).</p>Fórmula:C30H42N2O8S2Forma y color:SolidPeso molecular:622.79
