Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2275 productos de "Transportador de membrana / canal de iones"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PU-48
CAS:<p>PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 μM, exhibiting a significant diuretic effect in mouse models without</p>Fórmula:C14H12N2O3SForma y color:SolidPeso molecular:288.32URAT1 inhibitor 8
CAS:<p>URAT1 Inhibitor 8 (example 247) serves as a highly potent inhibitor of URAT1, demonstrating an IC50 value of 0.001 μM.</p>Fórmula:C19H13ClFN3O4SForma y color:SolidPeso molecular:433.84NaV1.7 Blocker-801
CAS:<p>NaV1.7 Blocker-801 is a potent NaV1.7 blocker.</p>Fórmula:C20H15ClF2N6O3S2Forma y color:SolidPeso molecular:524.95MCT1-IN-2
CAS:<p>SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.</p>Fórmula:C25H29N3O2SForma y color:SolidPeso molecular:435.58mGAT3/4-IN-2
CAS:<p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>Fórmula:C26H32ClN3OS2Forma y color:SolidPeso molecular:502.13GDC-6599
CAS:<p>GDC-6599 (Example 8) is an orally active inhibitor of the TRPA1 channel, potentially useful for researching TRPA1-mediated conditions, including pain [1].</p>Fórmula:C20H19ClN6O3Forma y color:SolidPeso molecular:426.86MONIRO-1
CAS:<p>MONIRO-1 blocks T/N-type Ca²⁺ channels: hCav2.2 (IC50: 34μM), hCav3.1 (3.3μM), hCav3.2 (1.7μM), hCav3.3 (7.2μM).</p>Fórmula:C23H24ClFN4O3Forma y color:SolidPeso molecular:458.92γ-Kainylglutamic acid
CAS:<p>gamma-Kainylglutamic acid is a selective amino acid-induced neuroexcitation antagonist.</p>Fórmula:C15H22N2O7Pureza:98%Forma y color:SolidPeso molecular:342.34(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Fórmula:C21H20ClNO6Pureza:98%Forma y color:SolidPeso molecular:417.84Y-27152
CAS:<p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>Fórmula:C21H22N2O4Pureza:98%Forma y color:SolidPeso molecular:366.41P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Fórmula:C12H17N5Pureza:99.85%Forma y color:SolidPeso molecular:231.3FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Forma y color:SolidPeso molecular:436.6CS-526
CAS:<p>CS-526 is a reversible proton pump inhibitor targeting the K+ site on H+,K+-ATPase, reducing gastric acid secretion and preventing mucosal lesions.</p>Fórmula:C20H22FN3OForma y color:SolidPeso molecular:339.41NMDA receptor modulator 6
CAS:<p>NMDA receptor regulator 6 (Compound 183) is an effective NMDA receptor regulator and has research value in neurological disorders.</p>Fórmula:C20H17FN2O4SForma y color:SolidPeso molecular:400.42Pumaprazole
CAS:<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Fórmula:C19H22N4O2Pureza:99.91%Forma y color:SolidPeso molecular:338.4ROMK-IN-32
CAS:<p>ROMK-IN-32 is an inhibitor of the extra-renal medullary potassium channel (ROMK) (IC50: 35 nM) and also inhibits hERG (IC50: 22 μM).</p>Fórmula:C24H28N4O5Forma y color:SolidPeso molecular:452.5N-Linolenoylethanolamine
CAS:<p>N-Linolenoylethanolamine (18:3 NAE), an endocannabinoid, functions as a vanillin receptor (TRPV1) agonist [1].</p>Fórmula:C20H35NO2Forma y color:SolidPeso molecular:321.505BMS-986169
CAS:<p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>Fórmula:C23H27FN2O2Pureza:97.61%Forma y color:SolidPeso molecular:382.47DNDS
CAS:<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Fórmula:C14H8N2Na2O10S2Pureza:99.92%Forma y color:Physical Description White Powder (Ntp 1992)Peso molecular:474.33Pristinamycin IA
CAS:<p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>Fórmula:C45H54N8O10Pureza:97.44%Forma y color:SolidPeso molecular:866.96CFTR corrector 6
CAS:<p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>Fórmula:C22H13F4N9Forma y color:SolidPeso molecular:479.39SLC13A5-IN-1
CAS:<p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>Fórmula:C19H19Cl3N2O3SPureza:99.67%Forma y color:SolidPeso molecular:461.79TRPC5 modulator-1
CAS:<p>TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.</p>Fórmula:C23H27FN2O4Forma y color:SolidPeso molecular:414.47AC-4
CAS:<p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>Fórmula:C26H25F3N4O2SForma y color:SolidPeso molecular:514.56PF 04531083
CAS:<p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>Fórmula:C17H16ClN5O2Pureza:99.85%Forma y color:SolidPeso molecular:357.79CP 154526
CAS:<p>CRF1 receptor antagonist</p>Fórmula:C23H33ClN4Pureza:98%Forma y color:SolidPeso molecular:400.99AMPA receptor modulator-2
CAS:<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Fórmula:C15H6F6N4OSPureza:99.8%Forma y color:SolidPeso molecular:404.29TRPC3/6-IN-2
CAS:<p>TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].</p>Fórmula:C18H23F2N5Forma y color:SolidPeso molecular:347.41PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Fórmula:C18H15N3O3Pureza:99.79%Forma y color:SolidPeso molecular:321.33Potassium Channel Activator 1
CAS:<p>Potassium Channel Activator 1 aids treatment of ADHD, schizophrenia, and mood disorders by targeting the dopaminergic system.</p>Fórmula:C19H23N3O3Pureza:99.86%Forma y color:SolidPeso molecular:341.4A-1165442
CAS:<p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>Fórmula:C22H20ClF2N3O2Forma y color:SolidPeso molecular:431.86Dibutyryl-cGMP sodium
CAS:<p>Bt2cGMP sodium is a cGMP analog, activates PKG, inhibits platelet [3H]-arachidonate, and induces analgesia via K+ channels.</p>Fórmula:C18H24N5NaO9PPureza:98%Forma y color:SolidPeso molecular:508.38NMDA receptor modulator 4
CAS:<p>NMDA receptor modulator 4 (Compound 169) can be used for the research of neurological disorder that is a potent modulator of NMDA receptor [1].</p>Fórmula:C13H9F3N2O3SForma y color:SolidPeso molecular:330.28P2X3 antagonist 34
CAS:<p>Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.</p>Fórmula:C24H26F2N4O3Pureza:98%Forma y color:SolidPeso molecular:456.48ML-252 hydrochloride
CAS:<p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>Fórmula:C20H24N2OHClForma y color:SolidPeso molecular:344.9Licostinel
CAS:<p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>Fórmula:C8H3Cl2N3O4Pureza:98.02%Forma y color:SolidPeso molecular:276.033′-Acetate-ATP
CAS:<p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>Fórmula:C12H18N5O14P3Forma y color:SolidPeso molecular:549.22GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Fórmula:C21H31F3O3Pureza:98%Forma y color:SolidPeso molecular:388.46Biricodar
CAS:<p>Biricodar is a P-glycoprotein and MRP-1 modulator.</p>Fórmula:C34H41N3O7Pureza:98%Forma y color:SolidPeso molecular:603.71ADX71441
CAS:<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Fórmula:C19H15ClF2N4O4Forma y color:SolidPeso molecular:436.8Cavα2δ1&NET-IN-3
CAS:<p>Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).</p>Fórmula:C24H30N6O2SForma y color:SolidPeso molecular:466.6p-fin4
CAS:<p>p-fin4, a peptide, inhibits STEP-GluA2 interaction, Ki 0.4 μM; may enhance cognition, has anxiolytic and antidepressant effects.</p>Fórmula:C39H53N8O18PForma y color:SolidPeso molecular:952.85Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Fórmula:C18H18FN7Forma y color:SolidPeso molecular:351.38CGP 64213
CAS:<p>CGP 64213 is a GABAb receptor agonist.</p>Fórmula:C26H36IN2O7PPureza:98%Forma y color:SolidPeso molecular:646.45PF-06456384
CAS:<p>PF-06456384 is a highly potent and selective NaV1.7 inhibitor with IC50 value of 0.01 nM.</p>Fórmula:C35H32F3N7O3S2Pureza:98%Forma y color:SolidPeso molecular:719.8AGN-201904Z
CAS:<p>AGN-201904Z is a slow-release, acid-resistant pro-PPI that turns into omeprazole, offering extended acid suppression.</p>Fórmula:C25H25N3NaO8S2Pureza:98%Forma y color:SolidPeso molecular:582.6VU6007477
CAS:<p>VU6007477: M1 PAM, EC50=230 nM, min. agonist activity, penetrates CNS, no seizure AEs.</p>Fórmula:C24H26N6O2Forma y color:SolidPeso molecular:430.5AR-C141990
CAS:<p>AR-C141990 is a lactate transporters inhibitor.</p>Fórmula:C26H28N4O4SForma y color:SolidPeso molecular:492.59Piprofurol
CAS:<p>Piprofurol is used as a Calcium channel blocker.</p>Fórmula:C26H33NO6Pureza:98%Forma y color:SolidPeso molecular:455.54(Rac)-AMG8379
CAS:<p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>Fórmula:C25H16ClF2N3O5SPureza:99.6%Forma y color:SolidPeso molecular:543.93
