Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2270 productos de "Transportador de membrana / canal de iones"
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Phenibut
CAS:<p>Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).</p>Fórmula:C10H13NO2Pureza:99.55%Forma y color:SolidPeso molecular:179.22γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Fórmula:C9H16N2O7Pureza:99.81%Forma y color:SolidPeso molecular:264.23GET73
CAS:<p>GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.</p>Fórmula:C13H16F3NO2Pureza:99.54%Forma y color:SolidPeso molecular:275.27Etimizol
CAS:<p>Etimizol improves memory by aiding the consolidation stage, effective against amnesia from hypoxia or brain injury.</p>Fórmula:C9H14N4O2Pureza:99%Forma y color:SolidPeso molecular:210.23Oxybuprocaine hydrochloride
CAS:<p>Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.</p>Fórmula:C17H29ClN2O3Pureza:>99.99%Forma y color:White Crystalline PowderPeso molecular:344.88DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Fórmula:C22H28Cl2O4Pureza:99.79% - 99.87%Forma y color:SolidPeso molecular:427.36Doxapram hydrochloride hydrate
CAS:<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Fórmula:C24H33ClN2O3C24H30N2O2·ClH·H2OPureza:99.64% - >99.99%Forma y color:SolidPeso molecular:432.99Glimepiride
CAS:<p>Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.</p>Fórmula:C24H34N4O5SPureza:97.84% - 98.87%Forma y color:White Cyrstalline SolidPeso molecular:490.62Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Fórmula:C21H29N3OPureza:99.62%Forma y color:SolidPeso molecular:339.473,4,5-Trimethoxycinnamic acid
CAS:<p>3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the</p>Fórmula:C12H14O5Pureza:98.91%Forma y color:SolidPeso molecular:238.24Butamben
CAS:<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Fórmula:C11H15NO2Pureza:99.43%Forma y color:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Peso molecular:193.24Penicillin G sodium salt
CAS:<p>Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a</p>Fórmula:C16H17N2NaO4SPureza:98.11%Forma y color:White To Off-White Crystalline PowderPeso molecular:356.37Leptomycin A
CAS:<p>Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.</p>Fórmula:C32H46O6Pureza:98%Forma y color:SolidPeso molecular:526.7EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Fórmula:C22H20F4N2O3Forma y color:SolidPeso molecular:436.4Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Fórmula:C18H27N5OForma y color:SolidPeso molecular:329.448Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Fórmula:C17H13N5O2Forma y color:SolidPeso molecular:319.32Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Fórmula:C29H33FN2O6Pureza:98.95% - 99.50%Forma y color:SolidPeso molecular:524.58GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Fórmula:C11H16N6OPureza:99.79%Forma y color:SoildPeso molecular:248.28TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Fórmula:C11H8ClN3Forma y color:SolidPeso molecular:217.66(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Fórmula:C6H11NO2Forma y color:SolidPeso molecular:129.16GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Fórmula:C185H273N49O45S6Pureza:98%Forma y color:SolidPeso molecular:4095.84BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Fórmula:C174H261N51O52S6Pureza:98%Forma y color:SolidPeso molecular:4091.65GeX-2
CAS:<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Fórmula:C103H169N43O27Forma y color:SolidPeso molecular:2441.72α,β-Methylene-ATP dilithium
CAS:<p>α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.</p>Fórmula:C11H16Li2N5O12P3Forma y color:SolidPeso molecular:517.07GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Forma y color:Odour SolidWAY-326766
CAS:<p>WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).</p>Fórmula:C21H23N3O5Pureza:98.76%Forma y color:SolidPeso molecular:397.42AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Fórmula:C20H25BrN4Forma y color:SolidPeso molecular:401.34Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Fórmula:C15H20O8Forma y color:SolidPeso molecular:328.317Trans (2,3)-Dihydrotetrabenazine
CAS:<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Fórmula:C19H29NO3Pureza:98%Forma y color:SolidPeso molecular:319.44LRRK2-IN-15
<p>LRRK2-IN-15 is an inhibitor of LRRK2. It exhibits an IC50 value of 5 nM in PBMC cells and 1.5 μM for BCRP. This compound is utilized in the research of Parkinson's disease.</p>Forma y color:Odour SolidTP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Fórmula:C16H15ClF2N6OForma y color:SolidPeso molecular:380.78Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Fórmula:C20H18O6Forma y color:SolidPeso molecular:354.358Jingzhaotoxin-XII TFA
<p>Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.</p>Forma y color:Odour Solid3-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Fórmula:C3H10NO2PForma y color:SolidPeso molecular:123.092Huwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Fórmula:C161H246N48O44S6Pureza:98%Forma y color:SolidPeso molecular:3750.36LY-466195
CAS:<p>LY-466195 is a competitive antagonist of GLUK5 receptor.</p>Fórmula:C16H24F2N2O4Forma y color:SolidPeso molecular:346.37Hyp9
CAS:<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Fórmula:C18H26O5Forma y color:SolidPeso molecular:322.40AChE/Aβ-IN-2
<p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>Fórmula:C20H25ClN4Forma y color:SolidPeso molecular:356.89Chlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Fórmula:C160H250F3N53O49S11Forma y color:SolidPeso molecular:4109.74JAMI1001A
CAS:<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Fórmula:C16H17F3N4O3SForma y color:SolidPeso molecular:402.39SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Fórmula:C19H13ClN2O2SPureza:99.86%Forma y color:SolidPeso molecular:368.84Homocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Fórmula:C10H16N4O3Forma y color:SolidPeso molecular:240.26Idactamab
CAS:<p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:146.2 kDaAnticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Fórmula:C22H24N4O2Forma y color:SolidPeso molecular:376.45Crofelemer
CAS:<p>Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.</p>Forma y color:Solid2,4,6-Tri-tert-butylphenol
CAS:<p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>Fórmula:C18H30OPureza:99.55%Forma y color:SolidPeso molecular:262.43Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Fórmula:C15H14F3N3O4S2Pureza:98% - >99.99%Forma y color:Crystals From Dioxane SolidPeso molecular:421.41Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.18Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Fórmula:C22H25ClN2O2Forma y color:SolidPeso molecular:384.9Resolvin D2 methyl ester
CAS:<p>RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.</p>Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.52
