Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(93 productos)
Mostrar 13 subcategorías más
Se han encontrado 2275 productos de "Transportador de membrana / canal de iones"
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Nepaprazole
CAS:<p>Nepaprazole (TY-11345) is a potent proton pump inhibitor; IC50: 5.8µM at pH 6.0, 9.9µM at pH 7.4. Better inhibition in weak acid.</p>Fórmula:C18H19N3O2SPureza:98%Forma y color:SolidPeso molecular:341.43RS 5773
CAS:<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Fórmula:C29H33ClN2O4SPureza:98%Forma y color:SolidPeso molecular:541.1JT010
CAS:<p>JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).</p>Fórmula:C16H19ClN2O3SPureza:99.75%Forma y color:SolidPeso molecular:354.85BTG 502
CAS:<p>BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).</p>Fórmula:C21H24BrNOPureza:99.30%Forma y color:SolidPeso molecular:386.33TROX-1
CAS:<p>TROX-1 is the activation state-dependent Cav2 channel antagonist.</p>Fórmula:C22H16ClFN6OPureza:98%Forma y color:SolidPeso molecular:434.85Dasolampanel etibutil
CAS:<p>Dasolampanel etibutil is a novel selective antagonist of ionotropic glutamate receptor 5 (iGluR5).</p>Fórmula:C23H32ClN5O3Forma y color:SolidPeso molecular:461.98U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Fórmula:C16H23N5Pureza:99.62%Forma y color:SolidPeso molecular:285.39(R)-3,4-DCPG
CAS:<p>AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors</p>Fórmula:C10H9NO6Pureza:98%Forma y color:SolidPeso molecular:239.18JM-1232
CAS:<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Fórmula:C24H27N3O2Forma y color:SolidPeso molecular:389.49Afizagabar
CAS:<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Fórmula:C19H12FN3O2SForma y color:SolidPeso molecular:365.38CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Fórmula:C18H28Cl2NO3PPureza:98%Forma y color:SolidPeso molecular:408.3CFTR corrector 12
CAS:<p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>Fórmula:C19H21ClN4O2S2Pureza:99.47%Forma y color:SolidPeso molecular:436.98M084 hydrochloride
CAS:<p>M084 hydrochloride, a TRPC4/5 channel blocker, exhibits IC50 values of 10.3 μM and 8.2 μM, respectively. This compound is noted for its antidepressant and anxiolytic effects [1] [2].</p>Fórmula:C11H16ClN3Forma y color:SolidPeso molecular:225.72PPADS tetrasodium
CAS:<p>PPADS tetrasodiuma is a P2X receptor antagonist and an inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle.</p>Fórmula:C14H10N3Na4O12PS2Pureza:95% - ≥95%Forma y color:SolidPeso molecular:599.3NaPi2b-IN-2
CAS:<p>NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human</p>Fórmula:C41H47ClF3N5O5SPureza:98%Forma y color:SolidPeso molecular:814.36Crobenetine hydrochloride
CAS:<p>Crobenetine hydrochloride, a sodium channel antagonist, is used potentially for the treatment of stroke.</p>Fórmula:C25H34ClNO2Forma y color:SolidPeso molecular:416CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Fórmula:C18H23Cl3NO3PForma y color:SolidPeso molecular:438.71XR9051 Hydrochloride
CAS:<p>XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein.</p>Fórmula:C39H39ClN4O5Forma y color:SolidPeso molecular:679.21α,β-Methylene ATP trisodium
CAS:<p>α,β-Methylene ATP trisodium is a ligand of P2X3 and P2X7 receptor.</p>Fórmula:C11H15N5Na3O12P3Pureza:99.66%Forma y color:SolidPeso molecular:571.15Dimethylamiloride
CAS:<p>Dimethylamiloride is a specific inhibitor of antiporters [1].</p>Fórmula:C8H12ClN7OPureza:98%Forma y color:SolidPeso molecular:257.68PF-05105679
CAS:<p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>Fórmula:C26H21FN2O3Pureza:99.84%Forma y color:SolidPeso molecular:428.45L 691121
CAS:<p>L 691121 is a class III antiarrhythmic compound. It also blocks potassium currents.</p>Fórmula:C22H25ClN4O5SPureza:98%Forma y color:SolidPeso molecular:492.98mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17Risevistinel
CAS:<p>Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative</p>Fórmula:C14H23N3O4Pureza:98%Forma y color:SolidPeso molecular:297.35LOE 908 hydrochloride
CAS:<p>Broad spectrum cation channel blocker</p>Fórmula:C41H49ClN2O9Pureza:98%Forma y color:SolidPeso molecular:749.29Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Fórmula:C5H11NO3SPureza:98%Forma y color:SolidPeso molecular:165.21NPEC-caged-(S)-AMPA
CAS:<p>AMPA receptor agonist</p>Fórmula:C16H17N3O8Pureza:98%Forma y color:SolidPeso molecular:379.32Sodium Channel inhibitor 4
CAS:<p>Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].</p>Fórmula:C19H18ClN3O4S2Pureza:98%Forma y color:SolidPeso molecular:451.95ZM 260384
CAS:<p>ZM 260384 is a potassium channel opener.</p>Fórmula:C15H11F4N3O4Forma y color:SolidPeso molecular:373.26NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.23CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Forma y color:SolidPeso molecular:444.76S-Pantoprazole sodium trihydrate
CAS:<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>Fórmula:C16H20F2N3NaO7SPureza:98%Forma y color:SolidPeso molecular:459.4TRPV2-selective blocker 1
CAS:<p>TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM.</p>Fórmula:C15H18OS2Forma y color:SolidPeso molecular:278.43CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Fórmula:C17H19N3O2Pureza:98%Forma y color:SolidPeso molecular:297.35Aneratrigine
CAS:<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Fórmula:C19H20ClF2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:487.97(R)-Elexacaftor
CAS:<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Fórmula:C26H34F3N7O4SPureza:98.991%Forma y color:SolidPeso molecular:597.65SCS
CAS:<p>SCS is a GABAA receptor antagonist.</p>Fórmula:C14H12N2O3Pureza:99.73%Forma y color:SolidPeso molecular:256.26KVI-020
CAS:<p>KVI-020: oral Kv1.5 blocker (IC50: 480nM), hERG inhibitor (IC50: 15100nM), potent antiarrhythmic for AF studies.</p>Fórmula:C20H25N3O5SForma y color:SolidPeso molecular:419.49Chromanol 293B
CAS:<p>slow delayed rectifier K+ current (IKs) blocker</p>Fórmula:C15H20N2O4SPureza:98%Forma y color:SolidPeso molecular:324.4GDC-0310
CAS:<p>GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.</p>Fórmula:C25H29Cl2FN2O4SPureza:99.877%Forma y color:SolidPeso molecular:543.48GNE-0723
CAS:<p>GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, GluN2A.blood-brain barrier (BBB) and Dravet syndrome and Alzheimer's disease (AD).</p>Fórmula:C16H8ClF6N5OSPureza:97.29% - 99.91%Forma y color:SolidPeso molecular:467.78PF-4778574
CAS:<p>PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).</p>Fórmula:C19H22N2O3S2Pureza:98%Forma y color:SolidPeso molecular:390.52Mioflazine
CAS:<p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>Fórmula:C29H30Cl2F2N4O2Pureza:98%Forma y color:SolidPeso molecular:575.48DPO-1
CAS:<p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5，也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>Fórmula:C22H29OPPureza:99.78%Forma y color:SolidPeso molecular:340.44CLP257
CAS:<p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>Fórmula:C14H14FN3O2SPureza:99.5%Forma y color:SolidPeso molecular:307.348-Pcpt-cGMP
CAS:<p>8-Pcpt-cGMP acts as an agonist for cyclic nucleotide-gated (CNG) channels with an EC50 of 0.5 μM and exhibits good membrane permeability. This compound is utilized in research to explore the role of CNG channels in visual and olfactory signal transduction.</p>Fórmula:C16H15ClN5O7PSForma y color:SolidPeso molecular:487.81BMS-199264 hydrochloride
CAS:<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Fórmula:C26H32Cl2N4O4SPureza:99.86%Forma y color:SolidPeso molecular:567.53Co 102862
CAS:<p>Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.</p>Fórmula:C14H12FN3O2Pureza:99.82%Forma y color:SolidPeso molecular:273.26Mesendogen
CAS:<p>Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7</p>Fórmula:C18H16ClF3N2OSPureza:99.66%Forma y color:SolidPeso molecular:400.85GSK3395879
CAS:<p>GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).</p>Fórmula:C20H15F4N3O5SPureza:98%Forma y color:SolidPeso molecular:485.41
