Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2272 productos de "Transportador de membrana / canal de iones"
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URAT1 inhibitor 1
CAS:<p>URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.</p>Fórmula:C19H15Br2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:569.29Clobutinol hydrochloride
CAS:<p>Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].</p>Fórmula:C14H23Cl2NOPureza:98%Forma y color:SolidPeso molecular:292.25Xeniafaraunol A
CAS:<p>Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].</p>Fórmula:C20H28O2Forma y color:SolidPeso molecular:300.446,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Fórmula:C15H10O4Pureza:99.44% - 99.67%Forma y color:SolidPeso molecular:254.24MK-2295
CAS:<p>MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.</p>Fórmula:C27H31FN6O2Pureza:98.83% - 99.44%Forma y color:SolidPeso molecular:490.57XR9051
CAS:<p>XR9051, a synthetic derivative of a natural compound, potently reverses P-glycoprotein MDR (EC50 = 1.4 nM) by inhibiting cytotoxic binding.</p>Fórmula:C39H38N4O5Forma y color:SolidPeso molecular:642.74Ritivixibat
CAS:<p>Ritivixibat inhibits IBAT and modulates bile acids, used in research for cardiovascular, metabolic, GI, and liver diseases.</p>Fórmula:C26H36N2O5S2Forma y color:SolidPeso molecular:520.7MK-8153
CAS:<p>MK-8153: Selective, potent ROMK inhibitor, orally active, IC50: ROMK EP 5 μM, hERG EP 34 μM; potential diuretic.</p>Fórmula:C24H28N2O6Forma y color:SolidPeso molecular:440.49Lingdolinurad
CAS:<p>Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.</p>Fórmula:C17H12BrN3O2Pureza:96.26%Forma y color:SolidPeso molecular:370.2JYL-1511
CAS:<p>JYL-1511 is the TRPV1 channel partial agonist.</p>Fórmula:C21H29N3O3S2Pureza:98%Forma y color:SolidPeso molecular:435.6D-erythro-Sphingosine hydrochloride
CAS:<p>D-erythro-Sphingosine HCl activates TRPM3 and dephosphorylates retinoblastoma protein.</p>Fórmula:C18H38ClNO2Forma y color:SolidPeso molecular:335.95TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.43NO-711ME
CAS:<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Fórmula:C22H24N2O3Pureza:99.54%Forma y color:SolidPeso molecular:364.44Kv3 modulator 2
CAS:<p>Kv3 modulator 2 is a potent Kv3 channels modulator.has analgesic activity and is used in the prophylaxis or treatment of related disorders.</p>Fórmula:C21H21N3O4Pureza:98%Forma y color:SolidPeso molecular:379.41TRPC5-IN-3
CAS:<p>TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).</p>Fórmula:C18H15ClF3N5OForma y color:SolidPeso molecular:409.79NS1219
CAS:<p>NS1219, an isomer of NS1209, is a selective AMPA antagonist for studying stroke, neuropathic pain, and epilepsy.</p>Fórmula:C24H28N4O7SForma y color:SolidPeso molecular:516.57Budiodarone
CAS:<p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>Fórmula:C27H31I2NO5Forma y color:SolidPeso molecular:703.35Kv3 modulator 3
CAS:<p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>Fórmula:C19H18N4O3Pureza:98%Forma y color:SolidPeso molecular:350.37CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Fórmula:C5H15ClNO2PForma y color:SolidPeso molecular:187.6(R)-Vanzacaftor
CAS:<p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>Fórmula:C32H39N7O4SForma y color:SolidPeso molecular:617.76Oct4 inducer-2
CAS:<p>Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].</p>Fórmula:C14H16N2O2SForma y color:SolidPeso molecular:276.35VU0463271
CAS:<p>VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>Fórmula:C19H18N4OS2Pureza:97.84% - 99.55%Forma y color:SolidPeso molecular:382.5Antiarrhythmic agent-1
CAS:<p>Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiac</p>Fórmula:C25H27N3O4SForma y color:SolidPeso molecular:465.56Diproqualone
CAS:<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Fórmula:C12H14N2O3Forma y color:SolidPeso molecular:234.255Naltiazem
CAS:<p>Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.</p>Fórmula:C26H28N2O4SPureza:98%Forma y color:SolidPeso molecular:464.58NPBA
CAS:<p>NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2). This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].</p>Fórmula:C16H14F3N3O3Forma y color:SolidPeso molecular:353.3Nalanthalide
CAS:<p>Nalanthalide, serving as a voltage-gated potassium channel Kv1.3 blocker (IC50 = 3.9 µM) with potential immunosuppressive properties, is applicable in the research of inflammatory immune diseases including neuroinflammation [1] [2].</p>Fórmula:C30H44O5Forma y color:SolidPeso molecular:484.67CRF1 receptor antagonist-1
CAS:<p>CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].</p>Fórmula:C27H28ClFN2O2SPureza:98%Forma y color:SolidPeso molecular:499.04Kv3 modulator 4
CAS:<p>Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.</p>Fórmula:C20H24N2O4Pureza:98%Forma y color:SolidPeso molecular:356.42SN40 hydrochloride
CAS:<p>SN40 hydrochloride is a potent inhibitor of amino acid transport (AAT), exhibiting inhibitory constants (Kis) of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM, and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1, and EAAT5, respectively. It is utilized in cancer research. [1]</p>Fórmula:C18H21ClN2O2Forma y color:SolidPeso molecular:332.82COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Forma y color:SolidPeso molecular:337.82BMT-108908
CAS:<p>BMT-108908 is a Negative Allosteric Modulator. It is selective for the NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.</p>Fórmula:C22H25FN2O2Forma y color:SolidPeso molecular:368.44Ebio1
CAS:<p>Ebio1, a selective activator of the voltage-gated potassium channel KCNQ2, enhances channel conductance by promoting the formation of an expanded gate at a saturation voltage of +50 mV, leading to increased channel activity [1].</p>Fórmula:C19H14FNOForma y color:SolidPeso molecular:291.32Coelenterazine h
CAS:<p>Coelenterazine H, a Ca2+ sensitive synthetic derivative, is a luminescent biomolecule used to measure Ca2+ changes.</p>Fórmula:C26H21N3O2Pureza:99.49%Forma y color:Yellow To Brownish PowderPeso molecular:407.46Etidocaine Hydrochloride
CAS:<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Fórmula:C17H29ClN2OPureza:99.86%Forma y color:SolidPeso molecular:312.88α,β-Methylene-ATP
CAS:<p>α,β-Methylene ATP，一种ATP的膦酸酯类似物，充当P2X3和P2X7受体的配体。该化合物对P2X1和P2X3表现出高选择性激动剂活性，而在P2X2, 4, 7受体上无活性。</p>Fórmula:C11H18N5O12P3Forma y color:SolidPeso molecular:505.21URAT1 inhibitor 6
CAS:<p>URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone,</p>Fórmula:C9H7BrN3NaO2S2Forma y color:SolidPeso molecular:356.2Glibornuride
CAS:<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>Fórmula:C18H26N2O4SPureza:99.5%Forma y color:SolidPeso molecular:366.48PF-05241328
CAS:<p>PF-05241328 is an effective and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (IC50: 31 nM).</p>Fórmula:C19H21ClN4O4SPureza:98%Forma y color:SolidPeso molecular:436.91VMAT2-IN-I HCl
CAS:<p>VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.</p>Fórmula:C25H32ClF4NO4Pureza:98%Forma y color:SolidPeso molecular:521.97L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.79PHP 501 trifluoroacetate
CAS:<p>GABAA antagonist</p>Fórmula:C20H21N3OPureza:98%Forma y color:SolidPeso molecular:319.4UBP316
CAS:<p>GluR5-containing kainate receptor antagonist</p>Fórmula:C20H19N3O6SPureza:98%Forma y color:SolidPeso molecular:429.45ADCI
CAS:<p>ADCI inhibits voltage-activated sodium and NMDA channels; boosts dopamine metabolism in prefrontal cortex and nucleus accumbens.</p>Fórmula:C16H14N2OPureza:98%Forma y color:SolidPeso molecular:250.3TCS 46b
CAS:<p>TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.</p>Fórmula:C22H23N3OPureza:99.78% - 99.78%Forma y color:SolidPeso molecular:345.4411-deoxy-PGF2a
CAS:<p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>Fórmula:C20H34O4Forma y color:SolidPeso molecular:338.48Zelquistinel
CAS:<p>Zelquistinel, an NMDA receptor agonist, aids research on depression, anxiety, and psychiatric disorders.</p>Fórmula:C15H25N3O5Forma y color:SolidPeso molecular:327.38(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Fórmula:C21H20INO6Pureza:99.24%Forma y color:SolidPeso molecular:509.29ARN 11391
CAS:<p>ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion</p>Fórmula:C22H29N3O3Forma y color:SolidPeso molecular:383.49JYL-273
CAS:<p>JYL-273 is a TRPV1 agonist.</p>Fórmula:C28H39NO4SForma y color:SolidPeso molecular:485.68
