Transportador de membrana / canal de iones
Los inhibidores de transportadores de membrana y canales iónicos son compuestos que bloquean la función de proteínas responsables del transporte de iones, nutrientes y otras moléculas a través de las membranas celulares. Estos inhibidores son cruciales para estudiar la regulación de la homeostasis celular, la transducción de señales y la neurotransmisión. Los inhibidores de transportadores de membrana y canales iónicos también son importantes para desarrollar tratamientos para trastornos como la epilepsia, las enfermedades cardiovasculares y los síndromes metabólicos. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad de transportadores de membrana y canales iónicos para apoyar su investigación en fisiología, neurociencia y farmacología.
Subcategorías de "Transportador de membrana / canal de iones"
- ABC(3 productos)
- ATPasa(93 productos)
- Receptor de adiponectina(5 productos)
- CFTR(64 productos)
- Receptor CGRP(51 productos)
- Canal de calcio(493 productos)
- Canal de cloruro(49 productos)
- Receptor GABA(336 productos)
- Transportador de monoamina(23 productos)
- Transportador de monocarboxilato(17 productos)
- NKCC(2 productos)
- NPC1L1(3 productos)
- Cotransportador de Na-K-Cl(8 productos)
- OAT(27 productos)
- OCT(7 productos)
- P-gp(53 productos)
- Canal de potasio(276 productos)
- Bomba de protones(39 productos)
- SGLT(30 productos)
- Canal de sodio(202 productos)
- Canal TRP / TRPV(92 productos)
Mostrar 13 subcategorías más
Se han encontrado 2272 productos de "Transportador de membrana / canal de iones"
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Leptomycin A
CAS:<p>Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.</p>Fórmula:C32H46O6Pureza:98%Forma y color:SolidPeso molecular:526.7A-317567
CAS:<p>A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, and it has antidepressant and antinociception effects[1][2].</p>Fórmula:C27H31N3Pureza:98%Forma y color:SolidPeso molecular:397.56BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Fórmula:C22H23F7N2O3Forma y color:SolidPeso molecular:496.418ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Fórmula:C120H182N38O43S6Pureza:98%Forma y color:SolidPeso molecular:3037Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H11NO2Forma y color:Off-White To Pale Yellow-Beige PowderPeso molecular:129.16ABCB1-IN-1
<p>ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis.</p>Fórmula:C36H33F3FeN2O4PSForma y color:SolidPeso molecular:733.54Tiludronate disodium hemihydrate
CAS:<p>Tiludronate: an oral bisphosphonate for bone disorder research; inhibits osteoclasts and reduces inflammation.</p>Fórmula:C14H16Cl2Na4O13P4S2Forma y color:SolidPeso molecular:743.16GSK2332255B
CAS:<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Fórmula:C18H19ClFN3O3SForma y color:SolidPeso molecular:411.88N-Oleoyl Glutamine
CAS:<p>N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.</p>Fórmula:C23H42N2O4Pureza:99.61%Forma y color:SolidPeso molecular:410.59LTGO-33
CAS:<p>LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.</p>Fórmula:C21H17F4N3O3SPureza:97.6%Forma y color:SoildPeso molecular:467.445-Hydroxy-2′,3,4′,7-tetramethoxyflavone
CAS:<p>5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.</p>Fórmula:C19H18O7Pureza:98%Forma y color:SoildPeso molecular:358.34S-Sulfo-L-cysteine sodium salt
CAS:<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Fórmula:C3H6NNaO5S2Pureza:99.88%Forma y color:SolidPeso molecular:223.2NF864
CAS:<p>NF864, a suramin analog, is a P2X1 receptor inhibitor.</p>Fórmula:C57H28N6Na12O41S12Pureza:98%Forma y color:SolidPeso molecular:2113.518β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Fórmula:C30H46O7SForma y color:SolidPeso molecular:550.75Phrixotoxin 3
CAS:<p>Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.</p>Fórmula:C176H269N51O48S6Pureza:98%Forma y color:SolidPeso molecular:4059.74TRPA1-IN-1
CAS:<p>TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.</p>Fórmula:C19H17ClN6O3Forma y color:SolidPeso molecular:412.8317α-Hydroxywithanolide D
<p>17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.</p>Fórmula:C28H46O7Forma y color:SolidPeso molecular:494.661Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Pureza:96.97%Forma y color:SolidConantokin G TFA
<p>Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.</p>Fórmula:C90H139F3N26O46Forma y color:SolidPeso molecular:2378.21GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Fórmula:C11H16N6OPureza:99.79%Forma y color:SoildPeso molecular:248.28LY-466195
CAS:<p>LY-466195 is a competitive antagonist of GLUK5 receptor.</p>Fórmula:C16H24F2N2O4Forma y color:SolidPeso molecular:346.37ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Fórmula:C168H250N46O41S8Pureza:98%Forma y color:SolidPeso molecular:3826.59Conantokin G
CAS:<p>GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.</p>Fórmula:C88H138N26O44Pureza:98%Forma y color:White Lyophilised SolidPeso molecular:2264.21NSC265473
CAS:<p>NSC265473 is an ABCG2 substrate.</p>Fórmula:C21H35N3O4SForma y color:SolidPeso molecular:425.58Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Fórmula:C18H33NOPureza:98%Forma y color:SolidPeso molecular:279.46α,β-Methylene-ATP dilithium
CAS:<p>α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.</p>Fórmula:C11H16Li2N5O12P3Forma y color:SolidPeso molecular:517.07MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Fórmula:C19H13BrFN3O2Pureza:98%Forma y color:SolidPeso molecular:414.23Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Fórmula:C15H20O8Forma y color:SolidPeso molecular:328.317Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Fórmula:C36H67NO17Forma y color:SolidPeso molecular:785.9224-oxo-2-Nonenal
CAS:<p>4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.</p>Fórmula:C9H14O2Forma y color:SolidPeso molecular:154.209Mesoridazine free base
CAS:<p>Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.</p>Fórmula:C21H26N2OS2Forma y color:SolidPeso molecular:386.57Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Forma y color:SolidPeso molecular:352.73Resolvin D2 methyl ester
CAS:<p>RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.</p>Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.52(+)-Lycoctonine
CAS:<p>Compound TJS1874 is a useful organic compound for research related to life sciences. The catalog number is TJS1874 and the CAS number is 26000-17-9.</p>Fórmula:C25H41NO7Forma y color:SolidPeso molecular:467.6PtdIns-(1,2-dioctanoyl) (sodium salt)
CAS:<p>PtdIns phosphates, a minor membrane lipid fraction, are vital for cell signaling. Synthetic PtdIns-(1,2-dioctanoyl) has C8:0 fatty acids and high solubility.</p>Fórmula:C25H47NaO13PForma y color:SolidPeso molecular:609.602Tariquidar dimesylate
CAS:<p>Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.</p>Fórmula:C80H94N8O25S4Pureza:98%Forma y color:SolidPeso molecular:1695.9Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Fórmula:C22H32O5Pureza:98%Forma y color:SolidPeso molecular:376.49BMS 199264
CAS:<p>BMS 199264 hydrochlorid a inhibitor of mitochondrial F1F0 ATP hydrolase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia.</p>Fórmula:C26H31ClN4O4SPureza:99.83%Forma y color:SoildPeso molecular:531.07Venturicidin A
CAS:<p>Venturicidin A is a macrolide antibiotic.</p>Fórmula:C41H67NO11Pureza:98%Forma y color:SolidPeso molecular:749.97Foslevcromakalim
CAS:<p>Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].</p>Fórmula:C16H19N2O6PForma y color:SolidPeso molecular:366.31α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Fórmula:C60H94N14O16Forma y color:SolidPeso molecular:1267.47P-gp inhibitor 13
<p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>Fórmula:C32H34O8Forma y color:SolidPeso molecular:546.61NT 13
CAS:<p>NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.</p>Fórmula:C18H30N4O7Pureza:98%Forma y color:SolidPeso molecular:414.453-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Fórmula:C3H10NO2PForma y color:SolidPeso molecular:123.092Vedroprevir
CAS:<p>Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.</p>Fórmula:C45H60ClN7O9SForma y color:SolidPeso molecular:910.53A 80915A
CAS:<p>A80915A: Semi-naphthoquinone antibiotic, blocks gastric (H(+)-K+)-ATPase; potency varies with enzyme conformation; K+ reduces binding rate.</p>Fórmula:C26H31Cl3O5Forma y color:SolidPeso molecular:529.88(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.4726-FAM-AEEAC-SHK TFA
<p>6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.</p>Fórmula:C196H295N55O57S7·xCHF3O2Forma y color:SolidPeso molecular:4558.23 (free acid)ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Fórmula:C106H178N40O32S7Pureza:98%Forma y color:White Lyophilised SolidPeso molecular:2749Homocarnosine TFA
<p>Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.</p>Fórmula:C12H17F3N4O5Forma y color:SolidPeso molecular:354.28
