Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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DSPE-PEG2000-YIGSR
<p>DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.</p>Forma y color:Odour Solid1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS:<p>Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.</p>Fórmula:C40H80NO8PPureza:99.23%Forma y color:SolidPeso molecular:734.04Rennin
CAS:<p>Rennin or Chymosin, a stomach enzyme in some animals, curdles milk by cleaving K-casein; key in cheese making.</p>Forma y color:Solid(S,S)-GSK321
CAS:<p>(S,S)-GSK321 is a (S,S)-enantiomer of GSK321 [1] .</p>Fórmula:C28H28FN5O3Forma y color:SolidPeso molecular:501.55FXIIa-IN-1 HCl
CAS:<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Fórmula:C21H17ClN2O6Pureza:99.61%Forma y color:SoildPeso molecular:428.82(±)13-HODE cholesteryl ester
CAS:<p>(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Fórmula:C45H76O3Forma y color:SolidPeso molecular:665.1Abiraterone N-oxide
CAS:<p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>Fórmula:C24H31NO2Forma y color:SolidPeso molecular:365.51Sphingolipid ceramide N-deacylase (SCDase)
CAS:<p>SCDase splits fatty acids from sphingosine in glycosphingolipids, forming lysoglycosphingolipids.</p>Forma y color:SolidZaragozic acid D(2)
CAS:<p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Fórmula:C36H50O14Pureza:98%Forma y color:SolidPeso molecular:706.77PDE4-IN-3
CAS:<p>PDE4-IN-3, a new oral drug, potently blocks PDE4 enzyme with 4.2 nM IC50.</p>Fórmula:C35H33FO8Forma y color:SolidPeso molecular:600.639Isodihydroauroglaucin
CAS:<p>Isodihydroauroglaucin is a useful organic compound for research related to life sciences. The catalog number is T124274 and the CAS number is 74886-31-0.</p>Fórmula:C19H24O3Forma y color:SolidPeso molecular:300.3983,3'-Bipyridine
CAS:<p>3,3'-Bipyridine is an inhibitor of CYP2A6, CYP3A4, and CYP2B6, and also inhibits gastric acid secretion in rats.</p>Fórmula:C10H8N2Forma y color:SolidPeso molecular:156.18(±)-threo-3-Methylglutamic acid
CAS:<p>glutamate transport blocker</p>Fórmula:C6H11NO4Pureza:98%Forma y color:SolidPeso molecular:161.16Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Fórmula:C12H16F2N2O4SForma y color:SolidPeso molecular:322.07988Beauverolide Ja
CAS:<p>Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.</p>Fórmula:C35H46N4O5Forma y color:SolidPeso molecular:602.76H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.Fórmula:C18H31N3O6Pureza:97.15%Forma y color:SolidPeso molecular:385.46(±)20-HDHA
CAS:<p>(±)20-HDHA is an autoxidation product and is a racemic mixture of Docosahexaenoic acid (DHA).</p>Fórmula:C22H32O3Pureza:98%Forma y color:SolidPeso molecular:344.49Azide-phenylalanine hydrochloride
CAS:UAA crosslinker 2 is a phenylalanine derivative.Fórmula:C9H11ClN4O2Pureza:98%Forma y color:SolidPeso molecular:242.66DSPE-PEG5000-CREKA
<p>DSPE-PEG5000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide is utilized for targeting tumor cells and tumor vasculature, exhibiting anti-tumor activity. DSPE-PEG5000-CREKA is applicable in drug delivery systems.</p>Forma y color:Odour Solid2'-Rhamnoechinacoside
CAS:<p>2'-Rhamnoechinacoside is a naturally occurring compound sourced from Cistanche tubulosa.</p>Fórmula:C41H56O24Forma y color:SolidPeso molecular:932.92H-Cho-Arg (trifluoroacetate salt)
CAS:<p>2H-Cho-Arg, a cationic lipid, enables gene delivery into cells and shows cytotoxicity at 92.7 μg/ml.</p>Fórmula:C43H73F6N5O7Forma y color:SolidPeso molecular:886.06DIPQUO hydrochloride
DIPQUO hydrochloride: ALP activator (EC50=6.27μM, C2C12 cells), induces osteoblast differentiation via p38 MAPK-β.Fórmula:C20H18ClN3OPureza:98.09%Forma y color:SoildPeso molecular:351.83BIRM 271
CAS:<p>BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.</p>Fórmula:C21H25N3OPureza:99.64%Forma y color:SoildPeso molecular:335.44N-Demethylerythromycin A
CAS:<p>N-Demethylerythromycin A, a metabolite of erythromycin from S. erythreus, may contaminate its preparations.</p>Fórmula:C36H65NO13Forma y color:SolidPeso molecular:719.9Pantothenoylcysteine
CAS:<p>Pantothenoylcysteine is a bioactive chemical.</p>Fórmula:C12H22N2O6SForma y color:SolidPeso molecular:322.38(E)-Dehydrodiconiferyl alcohol
CAS:<p>(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.</p>Fórmula:C20H22O6Forma y color:SolidPeso molecular:358.39HBPC-GSH
CAS:<p>HBPC-GSH, a derivative of glutathione, functions as an inhibitor for the glyoxalase system, specifically inhibiting cGloI and cGloII with IC50 values of 0.6μM</p>Fórmula:C17H23BrN4O8SForma y color:SolidPeso molecular:523.36ACAT-IN-8
CAS:<p>ACAT-IN-8 is an ACAT inhibitor which regulates cholesterol and blocks NF-κB mediated transcription.</p>Fórmula:C32H49N3O5SForma y color:SolidPeso molecular:587.82ecMetAP-IN-1
CAS:<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Fórmula:C13H11N3Pureza:99.34%Forma y color:SolidPeso molecular:209.25NoxA1ds
CAS:<p>Selective NOX1 inhibitor; IC50 at 20 nM; spares NOX2/4/5 and xanthine oxidase; reduces HT-29 O2- and hinders VEGF-induced cell migration.</p>Fórmula:C50H88N14O15Pureza:98%Forma y color:SolidPeso molecular:1125.33N-Desmethyl imatinib mesylate
CAS:<p>Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.</p>Fórmula:C29H33N7O4SForma y color:SolidPeso molecular:575.68Dextranase
CAS:<p>Dextranase, a glucan hydrolase, breaks down α-(1,6)-glucosidic bonds in dextran, useful in food, sugar modification, medicine, and more.</p>Forma y color:SolidVU533
CAS:<p>VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.</p>Fórmula:C21H22FN3O3S2Pureza:99.08%Forma y color:SolidPeso molecular:447.55Boc-L-aspartic acid 4-benzyl ester
CAS:<p>Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.</p>Fórmula:C16H21NO6Pureza:99.57%Forma y color:SolidPeso molecular:323.34Ellagic acid 4-O-β-D-xylopyranoside
CAS:<p>Ellagic acid 4-O-β-D-xylopyranoside, an ellagitannin found naturally, exhibits antimicrobial properties and acts as an inhibitor of xanthine oxidase, displaying</p>Fórmula:C19H14O12Forma y color:SolidPeso molecular:434.31FCE 28073
CAS:<p>FCE 28073 is a Monoamine oxidase B inibitor with IC50 of 0.45 uM.</p>Fórmula:C17H19FN2O2Pureza:99.92%Forma y color:SolidPeso molecular:302.34Diorcinol
CAS:<p>Diorcinol is a natural product that can be used as a reference standard. The CAS number of Diorcinol is 20282-75-1.</p>Fórmula:C14H14O3Forma y color:SolidPeso molecular:230.263Adenosine 5'-succinate
CAS:<p>Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.</p>Fórmula:C14H17N5O7Forma y color:SolidPeso molecular:367.318MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Forma y color:SolidPeso molecular:555.45DSPE-PEG2000-R9
<p>DSPE-PEG2000-R9 is a PEG compound composed of DSPE and polyarginine-9 peptide (R9) peptide. It can be used for drug delivery.</p>Forma y color:Odour SolidDSPE-PEG2000-GRGDS
<p>DSPE-PEG2000-GRGDS is a PEG-based compound formed from DSPE and the anti-adhesion peptide (GRGDS). GRGDS serves to inhibit the binding and adhesion between the extracellular matrix and cell surface integrins. This compound is applicable in drug delivery.</p>Forma y color:Odour SolidOno EI-601
CAS:<p>Ono EI-601 is the main metabolite of ONO-5046, the human neutrophil elastase inhibitor .</p>Fórmula:C15H14N2O6SPureza:98%Forma y color:SolidPeso molecular:350.35ACAT-IN-9
CAS:<p>ACAT-IN-9, derived from EP1236468A1 (example 207), is an ACAT inhibitor that suppresses NF-κB transcription.</p>Fórmula:C33H51N3O5SForma y color:SolidPeso molecular:601.85Risperidone E-oxime
CAS:<p>Risperidone E-oxime: Risperidone impurity, 5-HT2 & dopamine D2 blocker (Ki: 4.8, 5.9 nM), P-Glycoprotein inhibitor.</p>Fórmula:C23H28F2N4O2Pureza:98%Forma y color:SolidPeso molecular:430.49PKCζ/ι pseudosubstrate inhibitor
CAS:<p>PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of</p>Fórmula:C76H128N30O16Forma y color:SolidPeso molecular:1718.02N-β-alanyldopamine hydrochloride
CAS:<p>N-β-Alanyldopamine hydrochloride (NBAD hydrochloride) represents the primary dopamine derivative found in haemolymph [1].</p>Fórmula:C11H17ClN2O3Forma y color:SolidPeso molecular:260.72α-Glucosidase-IN-24
CAS:<p>α-Glucosidase-IN-24 (Compound 13), an α-Glucosidase inhibitor, exhibits an IC50 value of 451 μM and can be derived from Swertia kouitchensis [1].</p>Fórmula:C26H30O15Forma y color:SolidPeso molecular:582.51O-Desisobutyl-O-n-propyl Febuxostat
CAS:<p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>Fórmula:C15H14N2O3SForma y color:SolidPeso molecular:302.359AzNue5Ac
CAS:<p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>Fórmula:C11H18N4O8Pureza:≥98%Forma y color:SolidPeso molecular:334.28CYP1B1-IN-7
CAS:<p>CYP1B1-IN-7 is a CYP1B1 inhibitor that can be used in synergy with anticancer compounds for the treatment of cancers.</p>Fórmula:C19H13ClOPureza:99.49%Forma y color:SoildPeso molecular:292.76DSPE-PEG5000-APRPG
<p>DSPE-PEG5000-APRPG is a PEG compound composed of DSPE and the APRPG peptide, utilized for drug delivery.</p>Forma y color:Odour Solid1'-Hydroxy bufuralol
CAS:1'-Hydroxy bufuralol is a metabolite of bufuralol, an orally active β-adrenoceptor blocker used in the study of hypertension and cardiac arrhythmias.Fórmula:C16H23NO3Forma y color:SolidPeso molecular:277.36N-acetyl Dapsone
CAS:N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy, malaria, acne and various immune disorders.Fórmula:C14H14N2O3SPureza:99.83%Forma y color:WhitePeso molecular:290.34MJ33-OH lithium
CAS:<p>MJ33-OH lithium is a metabolite of MJ33.</p>Fórmula:C22H43F3LiO7PPureza:98%Forma y color:SolidPeso molecular:514.4811(R)-HETE
CAS:<p>11(R)-HETE aids in oocyte maturation in sea urchins and tentacle regeneration in hydras; it is also made by aspirin-influenced COX-2 and arachidonic acid.</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.473BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Forma y color:Odour SolidDansylphenylalanine
CAS:<p>Dansylphenylalanine is a typical fluorescent analyte.</p>Fórmula:C21H22N2O4SForma y color:SolidPeso molecular:398.48Guignardone J
CAS:<p>Guignardone J, a secondary metabolite, is isolated from the endophytic fungus Phyllosticta capitalensis [1].</p>Fórmula:C17H24O5Forma y color:SolidPeso molecular:308.37cis-5-Tetradecenoic acid
CAS:<p>cis-5-Tetradecenoic acid, found in blood, helps study Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency.</p>Fórmula:C14H26O2Forma y color:SolidPeso molecular:226.36Monoisobutyl phthalic acid
CAS:<p>Monoisobutyl phthalic acid is a metabolite of phthalate that is in human semen and in meconium.</p>Fórmula:C12H14O4Pureza:98%Forma y color:SolidPeso molecular:222.2410 FTHF disodium
CAS:<p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>Fórmula:C20H21N7Na2O7Forma y color:SolidPeso molecular:517.4IDO1-IN-12
CAS:<p>IDO1-IN-12 is a potent and orally available IDO1 inhibitor.</p>Fórmula:C21H19F3N2O2Forma y color:SolidPeso molecular:388.3913C C16 Sphingomyelin (d18:1/16:0)
CAS:<p>'13C-enriched C16 Sphingomyelin is a standard for quantifying C16 sphingomyelin by MS. Common in eggs; less in brain/milk; interacts with cholesterol.'</p>Fórmula:C39H79N2O6PForma y color:SolidPeso molecular:704.035(Ile8)-Oxytocin acetate
<p>(Ile8)-Oxytocin acetate is a neurohypophysial hormone analog of oxytocin produced in marsupials.</p>Fórmula:C45H70N12O14S2Forma y color:SolidPeso molecular:1067.24Monoglyceride lipase
CAS:<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>Forma y color:Solid(±)-Hexanoylcarnitine chloride
CAS:<p>(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into small compounds that can be utilized by the body.</p>Fórmula:C13H26ClNO4Pureza:99.45%Forma y color:SolidPeso molecular:295.8PTP Inhibitor IV
CAS:<p>PTP Inhibitor IV selectively inhibits DUSP14 (IC50=5.21µM) and other PTPs, affecting cellular signaling.</p>Fórmula:C26H26F6N2O4S2Pureza:99.76%Forma y color:SolidPeso molecular:608.62Penicillinase
CAS:<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Forma y color:SolidC-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS:<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Forma y color:SolidFABP4-IN-4
<p>FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.</p>Forma y color:Odour Solidα-Glucosidase-IN-73
<p>α-Glucosidase-IN-73 (compound 16b), an α-Glucosidase inhibitor, exhibits an IC 50 value of 0.158 μM and possesses the ability to activate PPAR γ. This compound is applicable in studies focusing on anti-diabetic and anti-inflammatory treatments.</p>Fórmula:C24H21N3O2SForma y color:SolidPeso molecular:415.51BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Fórmula:C44H52N8O5Forma y color:SolidPeso molecular:772.93PKM2 activator 6
<p>Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM,</p>Forma y color:Odour SolidTSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Fórmula:C35H51N3O3Forma y color:SolidPeso molecular:561.7983-O-Dihydro-p-coumaroyltohogenol
<p>3-O-Dihydro-p-coumaroyltohogenol functions as a PTP1B inhibitor (IC50 = 6.27 μM), exhibiting anti-diabetic and anti-obesity activities.</p>Fórmula:C39H60O5Forma y color:SolidPeso molecular:608.89ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Forma y color:SolidPhosphofructokinase
CAS:<p>Phosphofructokinase, a crucial glycolytic enzyme, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolysis pathway. Its activity is inhibited by the binding of Phosphoenolpyruvate (PEP), which regulates the rate of glycolysis. Additionally, Phosphofructokinase is utilized in the measurement of fructose-6-phosphate (fructose-6-phosphate) levels.</p>Forma y color:SolidIONIS PTP1BRx
CAS:<p>IONIS PTP1BRx (ISIS 404173) acts as an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). This compound exhibits anti-diabetic properties, making it suitable for research into insulin resistance related to obesity and type 2 diabetes.</p>Forma y color:SolidAntibacterial agent 237
<p>Anti bacterial agent 237 (compound Ru-8) acts as a potent antibacterial agent against Staphylococcus aureus, exhibiting minimum inhibitory concentrations (MICs) ranging from 0.78 to 1.56 μg/mL. It works by disrupting bacterial cell membranes, altering their permeability, and inducing the production of reactive oxygen species, which leads to bacterial cell death without promoting resistance. Additionally, Anti bacterial agent 237 demonstrates low hemolytic toxicity towards rabbit erythrocytes and Raw 264.7 cells. It has shown significant antibacterial activity in models of skin wound infections in mice and larval infections by the greater wax moth, effectively combating Staphylococcus aureus infections.</p>Fórmula:C65H69Cl3N10RuS2Forma y color:SolidPeso molecular:1261.87Imperatoxin A TFA
Imperatoxin A TFA, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, acts as an activator of Ca2+-release channels/ryanodine receptors (RyRs). It facilitates the influx of Ca2+ from the sarcoplasmic reticulum into the cell.Fórmula:C148H254N58O45S6·xC2HF3O2Forma y color:SolidPeso molecular:3758.35 (free base)NAD Synthetase
CAS:NAD Synthetase is responsible for the final step in the synthesis of Nicotinamide Adenine Dinucleotide (NAD). The enzyme sourced from Escherichia coli exhibits Km values of 200 μM for NAD, 11 μM for ATP, and 0.65 μM for ammonia. Conversely, NAD Synthetase derived from yeast demonstrates Km values of 170 μM for NAD, 190 μM for ATP, and 64 μM for ammonia. This enzyme is applicable in enzymatic assays for ATP, ammonia, urea, or creatinine and can also be used in enzymatic recycling methods. Additionally, NAD Synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative disorders.Forma y color:SolidHexasodium phytate
CAS:Hexasodium phytate is used potentially to treat vascular calcification and calciphylaxis.Fórmula:C6H12Na6O24P6Pureza:98%Forma y color:SolidPeso molecular:791.93Yokonoside
CAS:Yokonoside is a biochemical.Fórmula:C20H21NO11Forma y color:SolidPeso molecular:451.384FCPR03
CAS:FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.Fórmula:C15H19F2NO3Pureza:99.94%Forma y color:SolidPeso molecular:299.31Nap-FF
CAS:<p>Nap-FF is a cell-penetrating dipeptide used in the preparation of hydrogel chemical sensors and for research in targeted drug delivery.</p>Fórmula:C30H28N2O4Forma y color:SolidPeso molecular:480.554sn-Glycerol 3-phosphate lithium
<p>Lithium sn-glycerol 3-phosphate made by converting dihydroxyacetone phosphate via NADH from glycolysis.</p>Forma y color:SolidTpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Fórmula:C40H54BrN6O7PSForma y color:SolidPeso molecular:873.84IONIS PTP1BRx sodium
<p>IONIS PTP1BRx (ISIS 404173) sodium, an antisense inhibitor of protein tyrene phosphatase 1B (PTP-1B), exhibits antidiabetic properties. This compound is utilzed in researching insulin resistance and type 2 diabetes mellitus associated with obesity.</p>Forma y color:Odour SolidMaurocalcine TFA
<p>Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.</p>Fórmula:C156H270N56O46S6·xC2HF3O2Forma y color:SolidPeso molecular:3858.55 (free base)Febuxostat impurity 7
CAS:<p>Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H18N2O4SForma y color:SolidPeso molecular:334.39IPI-9119
CAS:<p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>Fórmula:C24H19F2N5O5Pureza:99.81%Forma y color:SolidPeso molecular:495.43Fasnall HCl
<p>Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.</p>Fórmula:C19H23ClN4SPureza:99.9%Forma y color:SoildPeso molecular:374.93ESI1
<p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>Fórmula:C18H18ClN5OForma y color:SolidPeso molecular:355.82PDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Forma y color:Odour SolidSofosbuvir impurity C
CAS:<p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>Fórmula:C22H29FN3O9PPureza:98%Forma y color:SolidPeso molecular:529.45Galactose 1-dehydrogenase
<p>Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.</p>Forma y color:Odour SolidFASN-IN-6
<p>FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs</p>Fórmula:C24H16BrF4N3O2Forma y color:SolidPeso molecular:534.313-cis-Retinyl acetate
CAS:<p>13-cis-Retinyl acetate: active 13-cis isomer of Retinyl acetate, metabolite of vitamin A.</p>Fórmula:C22H32O2Forma y color:SolidPeso molecular:328.49Glycerol-3-phosphate dehydrogenase
CAS:<p>Glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is an enzyme that catalyzes the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP), playing a crucial role in glycerol metabolism and energy production. This enzyme acts as the rate-limiting step in glycerol production within Saccharomyces cerevisiae, regulating glycerol formation and accumulation to aid the yeast in adapting to hyperosmotic environments. Additionally, glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is relevant in research within the field of metabolic engineering.</p>Forma y color:SolidDiacetinase
Diacetinase, a member of the esterase family, catalyzes the hydrolysis of glyceryl diacetate (Diacetin). It is utilized in the measurement of lipase activity.Forma y color:Odour Solid
