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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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  • DIPQUO hydrochloride


    DIPQUO hydrochloride: ALP activator (EC50=6.27μM, C2C12 cells), induces osteoblast differentiation via p38 MAPK-β.
    Fórmula:C20H18ClN3O
    Pureza:98.09%
    Forma y color:Soild
    Peso molecular:351.83
  • 2H-Cho-Arg (trifluoroacetate salt)

    CAS:
    <p>2H-Cho-Arg, a cationic lipid, enables gene delivery into cells and shows cytotoxicity at 92.7 μg/ml.</p>
    Fórmula:C43H73F6N5O7
    Forma y color:Solid
    Peso molecular:886.06
  • (25R)-12α-Hydroxyspirost-4-en-3-one

    CAS:
    <p>'(25R)-12α-Hydroxyspirost-4-en-3-one is a minor metabolite resulting from Nocardia globerula's metabolization of Hecogenin [1].'</p>
    Fórmula:C27H40O4
    Forma y color:Solid
    Peso molecular:428.6
  • RARα antagonist 1


    <p>Compound 21, an orally active and selective RARα antagonist, exhibits a potent inhibition of the retinoic acid receptor α with an IC50 of 4.6 nM [1].</p>
    Fórmula:C26H23NO4
    Forma y color:Solid
    Peso molecular:413.47
  • PDE4-IN-3

    CAS:
    <p>PDE4-IN-3, a new oral drug, potently blocks PDE4 enzyme with 4.2 nM IC50.</p>
    Fórmula:C35H33FO8
    Forma y color:Solid
    Peso molecular:600.639
  • 2-Nitrophenyl a-D-glucopyranoside

    CAS:
    <p>2-Nitrophenyl a-D-glucopyranoside is a substrate of β-glucosidase [1] .</p>
    Fórmula:C12H15NO8
    Forma y color:Solid
    Peso molecular:301.25
  • hCAII-IN-8

    CAS:
    <p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>
    Fórmula:C15H16N2O5S
    Pureza:99.73%
    Forma y color:Soild
    Peso molecular:336.36
  • Stephacidin B

    CAS:
    <p>Stephacidin B, from A. ochraceus, forms avrainvillamide in vitro. Cytotoxic to various cancer cells; induces apoptosis in hepatocarcinoma at 4 μM.</p>
    Fórmula:C52H54N6O8
    Forma y color:Solid
    Peso molecular:891.038
  • Sofosbuvir impurity B


    <p>Sofosbuvir impurity B, a less active byproduct, inhibits HCV RNA with potent anti-HCV effects.</p>
    Fórmula:C22H29FN3O9P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:529.45
  • Trityl olmesartan medoxomil impurity III

    CAS:
    <p>Trityl olmesartan medoxomil impurity III is an intermediate impurity in Olmesartan medoxomil synthesis.</p>
    Fórmula:C48H42N6O5
    Forma y color:Solid
    Peso molecular:782.88
  • 13,14-dihydro Prostaglandin E1

    CAS:
    <p>13,14-dihydro PGE1, a metabolite of PGE1, inhibits platelet aggregation and activates adenylate cyclase with IC50 of 31/21 nM and Kact 668 nM.</p>
    Fórmula:C20H36O5
    Forma y color:Solid
    Peso molecular:356.503
  • 4,7,10,13,16-Docosapentaenoic acid

    CAS:
    <p>4,7,10,13,16-Docosapentaenoic acid is an endogenous metabolite.</p>
    Fórmula:C22H34O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:330.51
  • MEY-003


    <p>MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potency</p>
    Forma y color:Odour Solid
  • Febuxostat sec-butoxy acid

    CAS:
    <p>Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>
    Fórmula:C16H16N2O3S
    Forma y color:Solid
    Peso molecular:316.37
  • (Rac)-Mono(3,5,5-trimethylhexyl) phthalate

    CAS:
    <p>(Rac)-Mono(3,5,5-trimethylhexyl) phthalate: a key metabolite of phthalate plasticizers with immune-suppressing effects.</p>
    Fórmula:C17H24O4
    Forma y color:Solid
    Peso molecular:292.37
  • 1,4-Butanediamine

    CAS:
    <p>1, 4-butanediamine is an aliphatic diamine compound that can be used as an analytical reagent to assist in precise detection experiments and also as a dye intermediate to facilitate the synthesis of various functional dyes.</p>
    Fórmula:C4H12N2
    Forma y color:Solid
    Peso molecular:88.1515
  • IDO-IN-15

    CAS:
    <p>IDO-IN-15 is an IDO1 inhibitor ( IC 50 &lt; 0.51 nM).</p>
    Fórmula:C29H39N5O4
    Forma y color:Solid
    Peso molecular:521.662
  • Pomonic acid

    CAS:
    <p>Pomonic acid, a triterpenoid, inhibits cholesterol ester build-up and ACAT activity.</p>
    Fórmula:C30H46O4
    Forma y color:Solid
    Peso molecular:470.68
  • (-)-Dihydroguaiaretic acid


    <p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>
    Fórmula:C20H26O4
    Forma y color:Solid
    Peso molecular:330.424
  • 13-cis-Vitamin A palmitate

    CAS:
    <p>13-cis-Retinyl palmitate in corn flakes is 75% as active as all-trans form.</p>
    Fórmula:C36H60O2
    Forma y color:Solid
    Peso molecular:524.86
  • Ethyl gentisate

    CAS:
    <p>Ethyl gentisate acts as a dual regulator of cell differentiation, promoting osteoblast differentiation while inhibiting osteoclast differentiation.</p>
    Fórmula:C9H10O4
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:182.17
  • Mitochondrial respiration-IN-1 hydrobromide


    <p>Mitochondrial inhibitor 49 (respiration-IN-1 hydrobromide, IC50=8.8 mg/mL) from US20110301180A1 reduces platelet respiration.</p>
    Forma y color:Solid
  • Archangelicin

    CAS:
    <p>Archangelicin is a useful organic compound for research related to life sciences. The catalog number is T125179 and the CAS number is 2607-56-9.</p>
    Fórmula:C24H26O7
    Forma y color:Solid
    Peso molecular:426.465
  • 2,4-Dimethylquinoline

    CAS:
    <p>2,4-Dimethylquinoline is a potential CYP1A2 inhibitor , and it also exhibits weak inhibitory activity against CYP2A5, CYP2A6, and CYP2B6.</p>
    Fórmula:C11H11N
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:157.21
  • Sucrose phosphorylase

    CAS:
    Sucrose phosphorylase, a bacterial enzyme, transforms sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose.
    Forma y color:Solid
  • VU534

    CAS:
    <p>VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related</p>
    Fórmula:C21H22FN3O3S2
    Pureza:98.85%
    Forma y color:Solid
    Peso molecular:447.55
  • MTHFD2-IN-3


    <p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>
    Fórmula:C22H19NO7S
    Forma y color:Solid
    Peso molecular:441.45
  • FUT8-IN-1


    <p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>
    Fórmula:C23H25ClN2O
    Forma y color:Solid
    Peso molecular:380.91
  • 20,26-Dihydroxyecdysone

    CAS:
    <p>20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite [1] .</p>
    Fórmula:C27H44O8
    Forma y color:Solid
    Peso molecular:496.63
  • β-Tetralone

    CAS:
    <p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>
    Fórmula:C10H10O
    Pureza:97.26% - 99.18%
    Forma y color:Clear To Yellow Liquid
    Peso molecular:146.19
  • Diorcinol

    CAS:
    <p>Diorcinol is a natural product that can be used as a reference standard. The CAS number of Diorcinol is 20282-75-1.</p>
    Fórmula:C14H14O3
    Forma y color:Solid
    Peso molecular:230.263
  • (-)-OPC-51803

    CAS:
    <p>(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.</p>
    Fórmula:C26H32ClN3O2
    Pureza:98.73% - 99.59%
    Forma y color:Soild
    Peso molecular:454
  • tetranor-PGEM

    CAS:
    <p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>
    Fórmula:C16H24O7
    Forma y color:Solid
    Peso molecular:328.361
  • D-γ-Glutamyl-D-glutamic acid

    CAS:
    D-γ-Glutamyl-D-glutamic acid is a linear polymer with repeating D-glutamic acid units, useful in studies of microbial cell walls and immunological recognition.
    Fórmula:C10H16N2O7
    Pureza:99.41%
    Forma y color:Solid
    Peso molecular:276.24
  • Casein kinase 1δ-IN-14

    CAS:
    <p>Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.</p>
    Fórmula:C17H11ClN4O2
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:338.75
  • Ellagic acid 4-O-β-D-xylopyranoside

    CAS:
    <p>Ellagic acid 4-O-β-D-xylopyranoside, an ellagitannin found naturally, exhibits antimicrobial properties and acts as an inhibitor of xanthine oxidase, displaying</p>
    Fórmula:C19H14O12
    Forma y color:Solid
    Peso molecular:434.31
  • 5-Aminolevulinic acid

    CAS:
    <p>5-Aminolevulinic acid: heme synthesis intermediate, photosensitizer, antineoplastic, prodrug, treats actinic keratosis with blue light.</p>
    Fórmula:C5H9NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:131.13
  • DSPE-PEG1000-ESBP


    <p>DSPE-PEG1000-ESBP is a PEG compound composed of DSPE and an E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>
    Forma y color:Odour Solid
  • Angiotensinogen (1-14), human acetate


    <p>Angiotensinogen (1-14), human acetate is a fragment of angiotensinogen which is a passive substrate of the renin-angiotensin system.</p>
    Fórmula:C85H126N24O21
    Pureza:98.4%
    Forma y color:Solid
    Peso molecular:1820.06
  • Ninerafaxstat trihydrochloride

    CAS:
    <p>Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation.</p>
    Fórmula:C22H32Cl3N3O5
    Pureza:99.71%
    Forma y color:Soild
    Peso molecular:524.87
  • MTHFD2-IN-4


    <p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>
    Fórmula:C26H21F6N2O5
    Forma y color:Solid
    Peso molecular:555.45
  • SDUY817


    <p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>
    Fórmula:C18H16IN3O3
    Forma y color:Solid
    Peso molecular:449.24
  • N-Decanoyl p-Nitroaniline

    CAS:
    <p>DepNA, a nitroaniline fatty acid amide, measures FAAH activity by releasing yellow dye p-nitroaniline upon exposure, detectable via spectrophotometer.</p>
    Fórmula:C16H24N2O3
    Forma y color:Solid
    Peso molecular:292.379
  • D-Sedoheptulose-7-phosphate (barium salt)

    CAS:
    <p>D-Sedoheptulose-7-phosphate: Key in pentose phosphate path, carbon fixation, and compound biosynthesis.</p>
    Fórmula:C7H17BaO10P
    Forma y color:Solid
    Peso molecular:429.504
  • Cellobiosan

    CAS:
    <p>Cellobiosan is an anhydro sugar formed during biofuel production from the fast pyrolysis of wood.</p>
    Fórmula:C12H20O10
    Forma y color:Solid
    Peso molecular:324.282
  • Adenosine 5'-succinate

    CAS:
    <p>Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.</p>
    Fórmula:C14H17N5O7
    Forma y color:Solid
    Peso molecular:367.318
  • SDUY816


    <p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>
    Fórmula:C18H16IN3O3
    Forma y color:Solid
    Peso molecular:449.24
  • AH078


    <p>AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.</p>
    Fórmula:C51H60F2N10O5S
    Forma y color:Solid
    Peso molecular:963.15
  • Diadenosine pentaphosphate pentasodium

    CAS:
    <p>Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.</p>
    Fórmula:C20H24N10Na5O22P5
    Forma y color:Solid
    Peso molecular:1026.28
  • NGR peptide

    CAS:
    <p>Cell-penetrating peptide</p>
    Fórmula:C20H36N10O8S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:608.69
  • Lysylcysteine TFA


    <p>Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.</p>
    Fórmula:C13H21F6N3O7S
    Forma y color:Solid
    Peso molecular:477.10044
  • CAIX Inhibitor S4

    CAS:
    <p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>
    Fórmula:C15H17N3O4S
    Pureza:99.07%
    Forma y color:Solid
    Peso molecular:335.38
  • α-Glucosidase-IN-84


    <p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>
    Fórmula:C25H29N7O3S
    Forma y color:Solid
    Peso molecular:507.608
  • 11-cis Retinol

    CAS:
    <p>11-cisRetinol, a vitamin A isomer, forms from a retinyl ester via RPE65. It's crucial for the visual cycle and cone pigment formation.</p>
    Fórmula:C20H30O
    Forma y color:Solid
    Peso molecular:286.459
  • IP3RPEP6

    CAS:
    IP3RPEP6 serves as a competitive inhibitor of IP3R. Its IC50 values for IP3R1, IP3R2, and IP3R3 are 9.0 μM, 3.9 μM, and 4.3 μM, respectively. This compound does not affect ryanodine receptors and Cx43 hemichannels, and it is capable of modulating intracellular calcium signaling.
    Fórmula:C49H79N15O24
    Forma y color:Solid
    Peso molecular:1262.24
  • Adrenergic Receptor-Targeted Compound Library


    <p>A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;</p>
    Forma y color:Odour Solid
  • PKM2-IN-4


    <p>Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial</p>
    Fórmula:C15H17BrClNO3Se
    Forma y color:Solid
    Peso molecular:453.62
  • ROR1 ligand-1


    <p>ROR1ligand-1 (9-1) serves as the ligand for PROTAC ROR1 degrader-1. By linking with ligands of either the VHL type or CRBN, the first selective and efficient ROR1 PROTAC molecule was designed and synthesized.</p>
    Fórmula:C23H30BrN7
    Forma y color:Solid
    Peso molecular:484.44
  • O-Desisobutyl-O-n-propyl Febuxostat

    CAS:
    <p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>
    Fórmula:C15H14N2O3S
    Forma y color:Solid
    Peso molecular:302.35
  • 2-Methylnicotinamide

    CAS:
    <p>2-Methylnicotinamide is an endogenous metabolite of nicotinamide and can be used for related research in the life sciences.</p>
    Fórmula:C7H8N2O
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:136.15
  • ACAT-IN-9

    CAS:
    <p>ACAT-IN-9, derived from EP1236468A1 (example 207), is an ACAT inhibitor that suppresses NF-κB transcription.</p>
    Fórmula:C33H51N3O5S
    Forma y color:Solid
    Peso molecular:601.85
  • Crotonyl-CoA tetrasodium


    Crotonyl-CoA tetrasodium is the tetrasodium salt form of Crotonyl-CoA. It serves as an intermediate in butyrate fermentation and in the metabolism of lysine and tryptophan. This compound plays a crucial role in the metabolism of fatty acids and amino acids.
    Fórmula:C25H36N7Na4O17P3S
    Forma y color:Solid
    Peso molecular:923.54
  • hCAIX/XII-IN-14


    <p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>
    Fórmula:C16H14F3N3O4S
    Forma y color:Solid
    Peso molecular:401.36
  • PNGase F

    CAS:
    <p>PNGase F is an endoglycosidase and amide hydrolase that catalyses the cleavage of internal glycosidic bonds in oligosaccharides.</p>
    Forma y color:Solid
  • O-desmethyl Mebeverine acid

    CAS:
    <p>O-desmethyl Mebeverine acid is a metabolite of Mebeverine.</p>
    Fórmula:C15H23NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:265.35
  • (Rac)-Azide-phenylalanine

    CAS:
    <p>(Rac)-Azide-phenylalanine: racemate, non-natural amino acid derivative for protein labeling.</p>
    Fórmula:C9H10N4O2
    Forma y color:Solid
    Peso molecular:206.20
  • (±)18-HETE

    CAS:
    <p>(±)18-HETE (18-Hydroxyeicosatetraenoic acid) is an arachidonic acid metabolite with a hydroxyl group on carbon 18, catalyzed by cytochrome P-450.</p>
    Fórmula:C20H32O3
    Forma y color:Solid
    Peso molecular:320.47
  • 9-cis-Vitamin A palmitate

    CAS:
    <p>9-cis-Vitamin A palmitate, a 9-cis isomer in corn flakes, has 26% activity of all-trans-vitamin A, the most active form.</p>
    Fórmula:C36H60O2
    Forma y color:Solid
    Peso molecular:524.874
  • EN3356

    CAS:
    <p>EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage</p>
    Fórmula:C16H13FN2OS
    Pureza:97.47%
    Forma y color:Soild
    Peso molecular:300.35
  • Dansylphenylalanine

    CAS:
    <p>Dansylphenylalanine is a typical fluorescent analyte.</p>
    Fórmula:C21H22N2O4S
    Forma y color:Solid
    Peso molecular:398.48
  • Antibacterial agent 132

    CAS:
    <p>Antibacterial agent 132 showed antimicrobial activity against C.</p>
    Fórmula:C24H17ClN4OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:444.94
  • Tetomilast

    CAS:
    <p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>
    Fórmula:C19H18N2O4S
    Forma y color:Solid
    Peso molecular:370.42
  • AP-III-a4 hydrochloride

    CAS:
    <p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>
    Fórmula:C31H44ClFN8O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:631.18
  • Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-

    CAS:
    <p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>
    Fórmula:C24H23NO5S
    Pureza:99.59%
    Forma y color:Soild
    Peso molecular:437.51
  • Seco Rapamycin ethyl ester


    <p>Seco Rapamycin ethyl ester, an open-ring metabolite of the Rapamycin derivative, reportedly does not impact mTOR function [1].</p>
    Fórmula:C53H83NO13
    Forma y color:Solid
    Peso molecular:942.23
  • Motapizone

    CAS:
    <p>Motapizone (NAT 05-239), a PDE3 inhibitor, moderates LPS-induced cytokine release and blocks platelet aggregation by boosting cAMP.</p>
    Fórmula:C12H12N4OS
    Forma y color:Solid
    Peso molecular:260.32
  • SHP2-IN-36


    <p>SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2 with an IC50 of 9.0 nM, and it exhibits an IC50 of 40 nM against p-ERK. Moreover, SHP2-IN-36 demonstrates significant antitumor activity in the KYSE520 xenograft mouse model and is applicable for research in the field of antitumor studies.</p>
    Forma y color:Odour Solid
  • (±)15-HEDE

    CAS:
    <p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>
    Fórmula:C20H36O3
    Forma y color:Solid
    Peso molecular:324.505
  • L-Lactic acid-13C3

    CAS:
    <p>L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.</p>
    Fórmula:C3H6O3
    Forma y color:Solid
    Peso molecular:93.055
  • γ-Glu-Phe

    CAS:
    <p>γ-Glu-Phe (γ-Glutamylphenylalanine) is a γ-3 glutamyl dipeptide found in sourdough.it is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae</p>
    Fórmula:C14H18N2O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:294.3
  • Impurity C of Alfacalcidol

    CAS:
    <p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>
    Fórmula:C35H49N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:575.78
  • Teprotide

    CAS:
    <p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>
    Fórmula:C53H76N14O12
    Forma y color:Solid
    Peso molecular:1101.26
  • 2,7"-Phloroglucinol-6,6'-bieckol

    CAS:
    <p>2,7"-Phloroglucinol-6,6'-bieckol serves as an effective oral dual α-amylase/α-glucosidase inhibitor, demonstrating IC 50 concentrations of 6.94 μM and 23.35 μM, respectively. This compound is beneficial in mitigating postprandial hyperglycemia among diabetic mice and is applicable in diabetes research [1].</p>
    Fórmula:C48H30O23
    Forma y color:Solid
    Peso molecular:974.74
  • Abiraterone N-oxide

    CAS:
    <p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>
    Fórmula:C24H31NO2
    Forma y color:Solid
    Peso molecular:365.51
  • Cholesterol esterase

    CAS:
    <p>Cholesterol esterase breaks down cholesterol ester into cholesterol and free fatty acids, aiding absorption.</p>
    Forma y color:Solid
  • Casein kinase 1δ-IN-15

    CAS:
    <p>Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].</p>
    Fórmula:C19H17FN6O
    Forma y color:Solid
    Peso molecular:364.38
  • (S)-3-Thienylglycine

    CAS:
    <p>(S)-3-Thienylglycine is a thiophene derivative and can be used to investigate the genotoxicity of the similar structures with thiophene derivatives.</p>
    Fórmula:C6H7NO2S
    Pureza:99.68%
    Forma y color:Solid
    Peso molecular:157.19
  • TRH Precursor Peptide


    <p>Thyrotropin Releasing Hormone Precursor Peptide</p>
    Fórmula:C42H75N19O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1006.17
  • N-acetyl Dapsone

    CAS:
    N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy, malaria, acne and various immune disorders.
    Fórmula:C14H14N2O3S
    Pureza:99.83%
    Forma y color:White
    Peso molecular:290.34
  • 3,3'-Bipyridine

    CAS:
    <p>3,3'-Bipyridine is an inhibitor of CYP2A6, CYP3A4, and CYP2B6, and also inhibits gastric acid secretion in rats.</p>
    Fórmula:C10H8N2
    Forma y color:Solid
    Peso molecular:156.18
  • BMS 195614

    CAS:
    <p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>
    Fórmula:C29H24N2O3
    Pureza:97.7%
    Forma y color:Solid
    Peso molecular:448.51
  • PLA2-IN-1


    <p>PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.</p>
    Forma y color:Odour Solid
  • Retinyl glucoside

    CAS:
    <p>Retinyl-β-D-glucoside, a biologically active metabolite of vitamin A, naturally occurs in fish and mammals.</p>
    Fórmula:C26H40O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:448.59
  • PKCζ/ι pseudosubstrate inhibitor

    CAS:
    <p>PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of</p>
    Fórmula:C76H128N30O16
    Forma y color:Solid
    Peso molecular:1718.02
  • Neo-inositol

    CAS:
    <p>Neo-Inositol, a stable, polar compound, is a rare natural inositol stereoisomer.</p>
    Fórmula:C6H12O6
    Forma y color:Solid
    Peso molecular:180.16
  • DSPE-PEG1000-PP1


    <p>DSPE-PEG1000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide targets inflammatory atherosclerotic plaques. DSPE-PEG1000-PP1 is suitable for drug delivery applications.</p>
    Forma y color:Odour Solid
  • GSK-3β/CK-1δ-IN-1


    GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.
    Fórmula:C22H17F3N4O
    Forma y color:Solid
    Peso molecular:410.39
  • human TDO2-IN-1


    <p>Human TDO2-IN-1 (Cpd-2) is a potent inhibitor of human TDO2, with an IC50 of 14.8 nM. It plays a significant role in studies related to metabolism, inflammation, and tumor immune surveillance.</p>
    Fórmula:C30H36N4O5
    Forma y color:Solid
    Peso molecular:532.631
  • Dextranase

    CAS:
    <p>Dextranase, a glucan hydrolase, breaks down α-(1,6)-glucosidic bonds in dextran, useful in food, sugar modification, medicine, and more.</p>
    Forma y color:Solid
  • Galactose oxidase

    CAS:
    <p>GOase, a type II copper enzyme from fungus, oxidizes alcohols to aldehydes and reduces O2 to H2O2.</p>
    Forma y color:Solid