Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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HX-600
CAS:<p>HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.</p>Fórmula:C29H30N2O2Forma y color:SolidPeso molecular:438.56(Rac)-3′-Hydroxy simvastatin
CAS:<p>(Rac)-3′-Hydroxy Simvastatin, a metabolite of Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, demonstrating a K i value of 0.2 nM.</p>Fórmula:C25H38O6Forma y color:SolidPeso molecular:434.57BMS 740808
CAS:<p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>Fórmula:C31H27F3N6O3Forma y color:SolidPeso molecular:588.58TMCB
CAS:<p>CK2 and ERK8 inhibitor</p>Fórmula:C11H9Br4N3O2Pureza:98%Forma y color:SolidPeso molecular:534.82Chaetomellic acid A
CAS:<p>Chaetomellic acid A inhibits farnesyltransferase (IC50=55nM), not active in cells, and selective over geranylgeranyltransferases (IC50: 92µM, 34µM).</p>Fórmula:C19H34O4Forma y color:SolidPeso molecular:326.47LEO-29102
CAS:<p>LEO-29102: Potent, selective PDE4 inhibitor, promising for treating skin diseases, phase 2 efficacy in atopic dermatitis.</p>Fórmula:C20H22Cl2N2O5Forma y color:SolidPeso molecular:441.31HIF-PHD-IN-2
CAS:<p>HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].</p>Fórmula:C17H15N5O3SForma y color:SolidPeso molecular:369.4α-Amylase-IN-2
CAS:α-Glucosidase-IN-3, an oxime ester derivative of oleanolic acid (OA), exhibits inhibitory activity against α-glucosidase (IC50 = 1.28 µM) and α-amylase (IC50 =Fórmula:C39H52BrNO4Forma y color:SolidPeso molecular:678.74RYL-552
CAS:<p>RYL-552 is a potent inhibitor of PfNDH2.</p>Fórmula:C24H17F4NO2Pureza:98%Forma y color:SolidPeso molecular:427.39HIF-1α-IN-3
CAS:<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Fórmula:C19H17N5O2Forma y color:SolidPeso molecular:347.37α-Glucosidase-IN-9
CAS:<p>α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].</p>Fórmula:C19H12N4OSForma y color:SolidPeso molecular:344.39Metyltetraprole
CAS:<p>Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.</p>Fórmula:C19H17ClN6O2Forma y color:SolidPeso molecular:396.83GKA-71
CAS:<p>GKA-71 is an effective glucokinase activator (GKA).</p>Fórmula:C21H23N3O6S2Forma y color:SolidPeso molecular:477.55JNJ-61803534
CAS:<p>JNJ-61803534: RORγt inverse agonist, IC50=9.6 nM, oral, anti-inflammatory, reduces IL-17A in T cells.</p>Fórmula:C23H23Cl2F6N3O4SForma y color:SolidPeso molecular:622.41Umbralisib tosylate
CAS:<p>Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.</p>Fórmula:C38H32F3N5O6SForma y color:SolidPeso molecular:743.75SYN20028567
CAS:<p>SYN20028567, an aromatase (CYP19) inhibitor, exhibits an IC50 value of 9.4 nM. It has potential applications in breast cancer research [1].</p>Fórmula:C20H29N3O3SForma y color:SolidPeso molecular:391.53mEH-IN-1
CAS:<p>mEH-IN-1 (Compound 62) is a potent mEH enzyme inhibitor with an IC50 of 2.2 nM, relevant in preeclampsia, hypercholanemia, and cancer research.</p>Fórmula:C16H17F6NOSForma y color:SolidPeso molecular:385.37hCAIX-IN-3
CAS:<p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>Fórmula:C21H21BrN6O4SForma y color:SolidPeso molecular:533.4Fmoc-5-aminopentanoic acid
CAS:<p>Fmoc-5-aminopentanoic acid: alkane, Fmoc-protected amine, carboxyl group, PROTAC linker, deprotects to free amine, forms amides with activators.</p>Fórmula:C20H21NO4Forma y color:SolidPeso molecular:339.39Antitumor agent-88
CAS:<p>Antitumor agent-88, a potent antimitotic, arrests G2/M phase, disrupts microtubules in breast cancer, and inhibits CYP1A1 (Ki: 1.4 μM).</p>Fórmula:C23H30N2O7SForma y color:SolidPeso molecular:478.56α-Glucosidase-IN-21
CAS:<p>α-Glucosidase-IN-21 (Compound 2B) is a highly potent and orally bioavailable inhibitor of α-glucosidase.</p>Fórmula:C24H23NO2SForma y color:SolidPeso molecular:389.513,3-Dimethyl-1-butanol
CAS:<p>3,3-Dimethyl-1-butanol (DMB) inhibits TMA/TMAO and affects p65 NF-κB, TGF-β1/Smad3 signaling; potential for CVD treatment.</p>Fórmula:C6H14OForma y color:SolidPeso molecular:102.17hCA IX-IN-2
<p>hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative</p>Fórmula:C23H24N2O4STeForma y color:SolidPeso molecular:552.11Carbonic anhydrase inhibitor 7
CAS:<p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>Fórmula:C23H17N3O5SForma y color:SolidPeso molecular:447.46Arasertaconazole
CAS:<p>Arasertaconazole, a sterol-14-alpha demethylation inhibitor, is used potentially for the treatment of vulvovaginal candcanidiasis.</p>Fórmula:C20H15Cl3N2OSForma y color:SolidPeso molecular:437.77A-908292
CAS:<p>A-908292: potent ACC2 inhibitor with 38 nM IC50, useful for studying fatty acid metabolism.</p>Fórmula:C18H20N2O4SForma y color:SolidPeso molecular:360.43FABP-IN-2
CAS:<p>FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.</p>Fórmula:C25H21ClN2O3Forma y color:SolidPeso molecular:432.9PDE4-IN-11
CAS:<p>PDE4-IN-11: Potent PDE4 inhibitor with strong bronchodilatory and anti-inflammatory effects for airway disease research.</p>Fórmula:C21H19FN2O2Forma y color:SolidPeso molecular:350.39Xanthine oxidase-IN-4
CAS:<p>Xanthine oxidase-IN-4: an oral XO inhibitor with 0.039 μM IC50, useful for hyperuricemia/gout research.</p>Fórmula:C15H13N5O2Forma y color:SolidPeso molecular:295.3PRRSV/CD163-IN-1
CAS:<p>PRRSV/CD163-IN-1 blocks PRRSV GP2a/GP4 and CD163-SRCR5, aiding PRRS research.</p>Fórmula:C25H24FN5O5S2Forma y color:SolidPeso molecular:557.62D-threo-PPMP hydrochloride
CAS:<p>D-threo-PPMP inhibits GlyCer synthetase; active enantiomer; reduces MDCK cell growth by 70% at 20 μM.</p>Fórmula:C29H51ClN2O3Forma y color:SolidPeso molecular:511.19α-Amylase/α-Glucosidase-IN-2
CAS:α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μMFórmula:C22H16ClN5Forma y color:SolidPeso molecular:385.85Lp-PLA2-IN-3
CAS:<p>Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.</p>Fórmula:C20H13ClF3N3O3SPureza:99.65%Forma y color:SolidPeso molecular:467.85Hydroxychlorodenafil
CAS:<p>Hydroxychlorodenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.</p>Fórmula:C19H23ClN4O3Forma y color:SolidPeso molecular:390.86HS79
CAS:<p>HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.</p>Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47Boc-Glu(OBzl)-OSu
CAS:<p>Boc-Glu(OBzl)-OSu can be used for the synthesis of solid phase peptides containing benzyl glutamate residues.</p>Fórmula:C21H26N2O8Forma y color:SolidPeso molecular:434.44AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Fórmula:C14H22N2OSPureza:98%Forma y color:SolidPeso molecular:266.4JTP-4819
CAS:<p>JTP-4819: potent PEP inhibitor, may treat Alzheimer's, boosts brain peptides and acetylcholine, aiding memory.</p>Fórmula:C19H25N3O4Forma y color:SolidPeso molecular:359.42PDE5-IN-4
CAS:<p>PDE5-IN-4, a phosphodiesterase 5 (PDE5) inhibitor, is utilized in research concerning acute myocardial infarction and reperfusion-related damage,</p>Fórmula:C21H27N5O5SForma y color:SolidPeso molecular:461.53Oxagrelate
CAS:<p>Oxagrelate inhibits cAMP phosphodiesterase and reduces platelet aggregation by collagen and ADP.</p>Fórmula:C14H16N2O4Forma y color:SolidPeso molecular:276.29Quinethazone
CAS:<p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>Fórmula:C10H12ClN3O3SForma y color:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecular:289.74MitoTEMPO hydrate
CAS:<p>MitoTEMPO, a mitochondria-targeted antioxidant, scavenges superoxide and alkyl radicals supporting potential therapy for mitochondrial dysfunction.</p>Fórmula:C29H35N2O2P·Cl·H2OForma y color:SolidPeso molecular:528.04Enpp-1-IN-5
CAS:<p>Enpp-1-IN-5 is a potent enpp-1 inhibitor with potential in cancer and infectious disease research.</p>Fórmula:C17H26N6O4SForma y color:SolidPeso molecular:410.49mIDH1-IN-1
CAS:<p>mIDH1-IN-1 is a selective mIDH1 inhibitor (IC50: 961.5 nM), blocks 2-HG production, and hinders IDH1 mutant cell growth (IC50: 41.8 nM).</p>Fórmula:C25H27N3O5Forma y color:SolidPeso molecular:449.5UK-414,495
CAS:<p>UK-414,495 is a potent, selective inhibitor of the neutral endopeptidase, the enzyme normally serves to break down the neuropeptide VIP.</p>Fórmula:C16H25N3O3SForma y color:SolidPeso molecular:339.45Xanthine oxidoreductase-IN-2
CAS:<p>Xanthine oxidoreductase-IN-2 inhibits XOR with 7.2 nM IC50 and shows hypouricemic effects in mice.</p>Fórmula:C21H19N3O2Forma y color:SolidPeso molecular:345.39Glucokinase activator 3
CAS:<p>Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.</p>Fórmula:C26H33N2O9PS2Forma y color:SolidPeso molecular:612.65α-Glucosidase-IN-8
CAS:<p>α-Glucosidase-IN-8 (Compound 4k) is a potent, competitive inhibitor of α-glucosidase. It displays an impressive IC50 value of 0.18 μg/mL [1].</p>Fórmula:C19H20FN3O2Forma y color:SolidPeso molecular:341.38hCAIX-IN-6
CAS:<p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>Fórmula:C18H12N2O4SForma y color:SolidPeso molecular:352.36Carbonic anhydrase inhibitor 13
CAS:<p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>Fórmula:C17H15N5O3S2Forma y color:SolidPeso molecular:401.46IDO1-IN-17
CAS:<p>IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .</p>Fórmula:C28H32BrClFN5O2Forma y color:SolidPeso molecular:604.94IDO-IN-14
CAS:<p>IDO-IN-14 is an IDO inhibitor (IC50: 0.6928 nM).</p>Fórmula:C23H23ClN4O2Forma y color:SolidPeso molecular:422.91CYP3A4-IN-1
CAS:<p>CYP3A4-IN-1 is a potent inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.085 μM).</p>Fórmula:C31H37N5O3SForma y color:SolidPeso molecular:559.72CK2-IN-6
CAS:<p>CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.</p>Fórmula:C19H16ClN7O2Forma y color:SolidPeso molecular:409.83RORγt modulator 2
CAS:RORγt modulator 2 is a modulator of retinol-related orphan receptor γt (RORyt) (IC50<50 nM) and can be used in the study of RORγt-mediated diseases such as painFórmula:C28H29ClN2O4SForma y color:SolidPeso molecular:525.06FXR agonist 4
<p>FXR agonist 4: EC50 of 1.05μM, treats hyperlipidemia, steatosis, insulin resistance, inflammation in DIO mice, for NAFLD research.</p>Fórmula:C21H28ClN3OForma y color:SolidPeso molecular:373.92Protizinic acid
CAS:<p>Protizinic acid is an oral NSAID with anti-inflammatory and antipyretic properties, inhibiting PLA2 at IC50 of 210μM.</p>Fórmula:C17H17NO3SForma y color:SolidPeso molecular:315.39ACC1/2-IN-2
CAS:<p>PF-3: potent ACC1/2 inhibitor; IC50: 22 nM (ACC1), 48 nM (ACC2); anti-cancer research potential.</p>Fórmula:C24H25N3O3Forma y color:SolidPeso molecular:403.47CYP1B1-IN-3
CAS:<p>CYP1B1-IN-3: strong CYP1B1 inhibitor (IC50: 6.6 nM); weak on CYP1A1/CYP1A2; hinders cell migration, invasion; blocks P-gp, AKT/ERK, FAK/SRC, EMT.</p>Fórmula:C20H16FN3O2S2Forma y color:SolidPeso molecular:413.49CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Fórmula:C19H15FN4OSForma y color:SolidPeso molecular:366.41Oxythiamine diphosphate
CAS:<p>Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).</p>Fórmula:C12H17N3O8P2SPureza:98%Forma y color:SolidPeso molecular:425.29(S)-Bromoenol lactone
CAS:<p>(S)-BEL, a chiral inhibitor of iPLA2β, blocks vasopressin-induced arachidonate release in A10 cells; IC50 = 2μM.</p>Fórmula:C16H13BrO2Forma y color:SolidPeso molecular:317.18PTP1B-IN-15
CAS:<p>PTP1B-IN-15 is a potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor that has shown research potential in type II diabetes and obesity.</p>Fórmula:C19H17Br2NO5SForma y color:SolidPeso molecular:531.22Carbonic anhydrase inhibitor 11
CAS:<p>Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.</p>Fórmula:C19H15F3N4O3S2Forma y color:SolidPeso molecular:468.47hCAIX/XII-IN-4
CAS:<p>hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).</p>Fórmula:C20H16N2O5Forma y color:SolidPeso molecular:364.3514(S)-HDHA
CAS:<p>DHA is an ω-3 important for development and therapy for inflammation and cancer; its derivative, 14(S)-HDHA, aids in reducing inflammation.</p>Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.4911β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Fórmula:C21H19ClN4OForma y color:SolidPeso molecular:378.86DGAT1-IN-3
CAS:<p>DGAT1-IN-3: a potent, selective DGAT-1 inhibitor (IC50: 38 nM human, 120 nM rat), oral, for obesity and dyslipidemia research.</p>Fórmula:C20H19F3N4O3Forma y color:SolidPeso molecular:420.39Nampt-IN-7
CAS:<p>Nampt-IN-7 (GF8) inhibits NAMPT (IC50: 7.31 μM) and kills HepG2 cells (IC50: 24.28 μM).</p>Fórmula:C20H21N5O3Forma y color:SolidPeso molecular:379.41(±)-γ-Tocopherol
CAS:<p>(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.</p>Fórmula:C28H48O2Forma y color:SolidPeso molecular:416.68CL 242817
CAS:<p>CL 242817 is an inhibitor of angiotensin converting enzyme (ACE).</p>Fórmula:C18H21NO5SForma y color:SolidPeso molecular:363.4311β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Fórmula:C13H9F3N2OForma y color:SolidPeso molecular:266.22FASN-IN-4
CAS:<p>FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.</p>Fórmula:C26H27N3O4SPureza:98%Forma y color:SolidPeso molecular:477.58BMS-351
CAS:<p>BMS-351: potent, selective CYP17A1 inhibitor, promising for prostate cancer, minimal side effects.</p>Fórmula:C15H12F3N3Forma y color:SolidPeso molecular:291.27AMPD2 inhibitor 2
<p>AMPD2 inhibitor 2: strong h/mAMPD2 blocker, IC50s: 0.1/0.28μM. Potentially assesses AMPD2's role in high-fat diet mice.</p>Fórmula:C26H27F2N3O3Forma y color:SolidPeso molecular:467.51ME-143
CAS:<p>ME-143, a 2nd-gen NADH oxidase inhibitor, blocks WNT/β-catenin pathway, active against various cancers in vitro/vivo.</p>Fórmula:C21H18O4Forma y color:SolidPeso molecular:334.37LEO 39652
CAS:<p>LEO 39652: Dual-soft PDE4 inhibitor, IC50s: PDE4A/B: 1.2 nM, PDE4C: 3.0 nM, PDE4D: 3.8 nM; TNF-α IC50: 6.0 nM; for Atopic dermatitis research.</p>Fórmula:C23H23N3O5Forma y color:SolidPeso molecular:421.453-Oxo-hop-22(29)-ene
CAS:<p>3-Oxo-hop-22(29)-ene inhibits yeast α-glucosidase, moderately affects T. cruzi and L. mexicana, and has slight anti-inflammatory activity.</p>Fórmula:C30H48OForma y color:SolidPeso molecular:424.7hCAXII-IN-4
CAS:<p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>Fórmula:C22H27N5O6SForma y color:SolidPeso molecular:489.54Antiproliferative agent-10
<p>Antiproliferative agent-10: Ruthenium(II) complex that blocks cancer cell growth by halting mitochondrial calcium uptake.</p>Fórmula:C35H36Cl2N7PRuForma y color:SolidPeso molecular:757.66MK-0952
CAS:<p>MK-0952 treats memory loss and cognitive issues; it's a potent, selective PDE4 inhibitor with restricted blood activity.</p>Fórmula:C28H22FN3O4Forma y color:SolidPeso molecular:483.49MitoPBN
CAS:<p>MitoPBN: mitochondria-targeted antioxidant, inhibits UCP1-3 at 250 nM, traps hydroxyl & carbon radicals, prevents lipid peroxidation.</p>Fórmula:C33H37BrNO2PForma y color:SolidPeso molecular:590.542hCA I-IN-2
CAS:<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Fórmula:C26H20BrN5O3SForma y color:SolidPeso molecular:562.44RORγt modulator 3
CAS:<p>RORγt modulator 3 is a modulator of retinol-related orphan receptor γt (RORγt) and can be used to study RORγt-mediated diseases such as pain, COPD, inflammation</p>Fórmula:C25H25ClFN3O4SForma y color:SolidPeso molecular:518Zidovudine glucuronide
CAS:<p>Zidovudine glucuronide: an NRTI antiretroviral for HIV/AIDS treatment; blocks HIV reverse transcriptase, stops viral DNA formation.</p>Fórmula:C16H21N5O10Forma y color:SolidPeso molecular:443.37BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Fórmula:C18H18O4SForma y color:SolidPeso molecular:330.4JZP-MA-13
<p>JZP-MA-13: selective α/β-hydrolase domain 6 inhibitor, IC 50 392 nM, doesn't inhibit MAGL/ABHD12/FAAH, used in PET imaging.</p>Fórmula:C14H15FN4O3SForma y color:SolidPeso molecular:338.36BRD9500
CAS:<p>BRD9500 is an oral PDE3 inhibitor, IC50: 10 nM (PDE3A), 27 nM (PDE3B); effective in SK-MEL-3 cancer model.</p>Fórmula:C15H18FN3O2Forma y color:SolidPeso molecular:291.32Enpp-1-IN-17
CAS:<p>Enpp-1-IN-17 (example 274) is a potent inhibitor of ENPP1, exhibiting inhibition constants (Ki values) of 100 nM-1 μM for cGAMP hydrolysis and >1 μM for ATP</p>Fórmula:C18H24N4O2Forma y color:SolidPeso molecular:328.41Glyoxalase I inhibitor 4
CAS:<p>Glyoxalase I inhibitor 4 is a potent inhibitor of glyoxalase I (GLO1) (Ki: 10 nM).</p>Fórmula:C17H21IN4O8SForma y color:SolidPeso molecular:568.34hCAI/II-IN-4
CAS:<p>hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>Fórmula:C15H15N3O5S2Forma y color:SolidPeso molecular:381.43THPP-4
CAS:<p>THPP-4 inhibits phosphodiesterase 10A (PDE10A).</p>Fórmula:C20H21ClN6O2Forma y color:SolidPeso molecular:412.87Glyoxalase I inhibitor 7
CAS:<p>Glyoxalase I inhibitor 7 (Compound 6) is a potent inhibitor of glyoxalase I (Glo-I) with an IC50 of 3.65 μM. It exhibits potential as an anticancer agent [1].</p>Fórmula:C17H16N4O3SForma y color:SolidPeso molecular:356.4BTX161
CAS:<p>BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.</p>Fórmula:C15H16N2O3Forma y color:SolidPeso molecular:272.3BMP-22
CAS:<p>BMP-22 selectively inhibits autotaxin (IC50=170 nM), blocks LPA production and MM1 cell invasion, and reduces lung metastases in mice at 0.5 mg/kg/day.</p>Fórmula:C22H39O3PForma y color:SolidPeso molecular:382.52SAHO
CAS:<p>SAHO is a methyl donor cleaved by SAM enzymes into adenosylhomocysteine and thioadenosine derivatives.</p>Fórmula:C14H20N6O6SForma y color:SolidPeso molecular:400.41Diapocynin
CAS:<p>Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase.</p>Fórmula:C18H18O6Forma y color:SolidPeso molecular:330.33Tebuconazole-d9
CAS:<p>Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.</p>Fórmula:C16H13ClD9N3OForma y color:SolidPeso molecular:316.87FABP4/5-IN-5
CAS:<p>FABP4/5-IN-5 (compound D9) serves as a potent inhibitor of both FABP 4 and FABP 5, demonstrating IC50 values of 4.68 μM and 10.72 μM, respectively. It is notably effective in addressing metabolic disorders such as diabetes mellitus [1].</p>Fórmula:C23H14ClF2NO4SForma y color:SolidPeso molecular:473.88RO6806051
CAS:RO6806051 (compound 12) is a potent dual inhibitor of fatty acid binding proteins 4 and 5 (FABP4 and FABP5), exhibiting excellent selectivity and absorption, distribution, metabolism, and excretion (eADME) properties.Fórmula:C21H19ClN6Forma y color:SolidPeso molecular:390.87
