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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • Varespladib methyl

    CAS:
    <p>Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.</p>
    Fórmula:C22H22N2O5
    Pureza:99.42% - 99.97%
    Forma y color:Solid
    Peso molecular:394.42
  • NEP-IN-1

    CAS:
    <p>NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.</p>
    Fórmula:C21H30ClNO4
    Pureza:99.69%
    Forma y color:Solid
    Peso molecular:395.92
  • Dechloro Rivaroxaban

    CAS:
    <p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>
    Fórmula:C19H19N3O5S
    Pureza:98.63%
    Forma y color:Solid
    Peso molecular:401.44
  • ER 50891

    CAS:
    <p>ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.</p>
    Fórmula:C29H24N2O2
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:432.51
  • DGAT-1 inhibitor 2

    CAS:
    <p>DGAT-1 inhibitor 2: effective against obesity, targets enzyme in triglyceride synthesis for diabetes treatment.</p>
    Fórmula:C24H28N4O3
    Pureza:98.36%
    Forma y color:Solid
    Peso molecular:420.5
  • ML400

    CAS:
    <p>ML400 (CID73050863) is an allosteric inhibitor of LMPTP with an EC50 of 1μM. ML400 displays good cell-based activity and rodent pharmacokinetics.</p>
    Fórmula:C24H29N3O
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:375.51
  • Cis-22a

    CAS:
    <p>Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.</p>
    Fórmula:C24H30F3N3O2
    Pureza:99.07%
    Forma y color:Solid
    Peso molecular:449.51
  • Xanthine oxidase-IN-1

    CAS:
    <p>Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM.</p>
    Fórmula:C16H8F2N2O3
    Pureza:97.36% - 99.22%
    Forma y color:Solid
    Peso molecular:314.24
  • Mutant IDH1-IN-2

    CAS:
    <p>Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of <22 nM in LS-</p>
    Fórmula:C24H31F2N5O2
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:459.53
  • (-)-Mesembrine

    CAS:
    <p>Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).</p>
    Fórmula:C17H23NO3
    Forma y color:Solid
    Peso molecular:289.37
  • Dihydrokainic acid

    CAS:
    EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
    Fórmula:C10H17NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:215.25
  • 11β-HSD2-IN-2

    CAS:
    <p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>
    Fórmula:C22H21NO2
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:331.41
  • AZD 4407

    CAS:
    <p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>
    Fórmula:C19H21NO3S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:375.5
  • IDO1-IN-25

    CAS:
    <p>IDO1-IN-25, a dual inhibitor of IDO1/TDO2, showcases IC50 values of 0.17 μM for IDO1 and 3.2 μM for TDO2. It effectively suppresses NO production in RAW264.7 cells following stimulation with lipopolysaccharide (LPS). Additionally, IDO1-IN-25 demonstrates anti-inflammatory properties in a mouse ear edema model of acute inflammation induced by croton oil.</p>
    Fórmula:C14H8Cl3NO2S
    Forma y color:Solid
    Peso molecular:360.64
  • DLCI-1

    CAS:
    <p>DLCI-1 is a potent and selective oral inhibitor of cytochrome P450 2A6 (CYP2A6), significantly reducing self-administered nicotine doses in both male and female mice.</p>
    Fórmula:C12H14N2S
    Forma y color:Solid
    Peso molecular:218.32
  • 2R,4R-Sacubitril

    CAS:
    <p>2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.</p>
    Fórmula:C24H29NO5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:411.49
  • Utibaprilat

    CAS:
    <p>Utibaprilat is the primary degradation product of Utibapril and functions as an ACE inhibitor.</p>
    Fórmula:C20H27N3O5S
    Forma y color:Solid
    Peso molecular:421.51
  • hCAIX/XII-IN-15

    CAS:
    <p>hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.</p>
    Fórmula:C17H18O4S
    Forma y color:Solid
    Peso molecular:318.387
  • Calcium 2-hydroxypropanoate pentahydrate

    CAS:
    <p>Calcium 2-hydroxypropanoate (pentahydrate) acts as an activator of the hydroxyl-carboxylic acid receptor 1 (HCAR1) and serves as an epigenetic regulator that induces lysine residue lactylation. This compound, a glycolysis end product, bridges the gap between glycolysis and oxidative phosphorylation and functions as a tumor metabolite with immunoprotective effects of lactate in antitumor immunity.</p>
    Fórmula:C3H5O3CaH2O
    Forma y color:Solid
    Peso molecular:154.147
  • 6′SLN

    CAS:
    <p>6′SLN is a characteristic glycan found on the surface of cancer-related extracellular vesicles (EVs) and serves as the primary form of protein glycosylation within EVs. Additionally, 6′SLN, a derivative of sialic acid, interacts with hemagglutinins (HAs) from both human and avian influenza strains, making it relevant in the study of anti-influenza drugs.</p>
    Fórmula:C25H42N2O19
    Forma y color:Solid
    Peso molecular:674.6