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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • PAT-347

    CAS:
    <p>PAT-347 is a potent inhibitor of Autotaxin, an enzyme linked to cell survival and diseases like cancer and fibrosis.</p>
    Fórmula:C28H21ClF2N2O3S
    Forma y color:Solid
    Peso molecular:538.99
  • hCAII-IN-4

    CAS:
    <p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>
    Fórmula:C31H23NO9
    Forma y color:Solid
    Peso molecular:553.52
  • Tovinontrine

    CAS:
    <p>Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.</p>
    Fórmula:C21H26N6O2
    Pureza:98.14%
    Forma y color:Solid
    Peso molecular:394.47
  • CYP1B1-IN-2


    <p>CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].</p>
    Fórmula:C20H11F3O2
    Forma y color:Solid
    Peso molecular:340.3
  • RORγt inhibitor 4

    CAS:
    <p>RORγt inhibitor 4 (Compound 9a) is an orally active RORγt inhibitor capable of penetrating the central nervous system. It has been shown to improve experimental autoimmune encephalomyelitis.</p>
    Fórmula:C22H16Cl2F3NO4S
    Forma y color:Solid
    Peso molecular:518.333
  • HIF-2α-IN-5

    CAS:
    <p>HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of &lt; 50 nM [1].</p>
    Fórmula:C15H12F4O3S2
    Forma y color:Solid
    Peso molecular:380.38
  • hMAO-B/MB-COMT-IN-2


    <p>Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) &amp; MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.</p>
    Fórmula:C17H18N2O3
    Forma y color:Solid
    Peso molecular:298.34
  • L-739750

    CAS:
    <p>L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.</p>
    Fórmula:C23H39N3O6S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:517.7
  • PENAO

    CAS:
    <p>PENAO is a potent mitochondrial toxin for tumor cells. It deactivates the mitochondria of tumor cells by targeting the adenine nucleotide translocase in the cell membrane.</p>
    Fórmula:C13H19AsN2O5S
    Forma y color:Solid
    Peso molecular:390.29
  • CIT-ALD

    CAS:
    <p>CIT-ALD is an aldehyde intermediate formed during the metabolism of Citalopram. It has potential applications in the research of neurological disorders.</p>
    Fórmula:C18H14FNO2
    Peso molecular:295.31
  • Lumirubin

    CAS:
    <p>Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.</p>
    Fórmula:C33H36N4O6
    Forma y color:Solid
    Peso molecular:584.66
  • MDL-100240

    CAS:
    <p>MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.</p>
    Fórmula:C26H28N2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:480.58
  • Atorvastatin 3-Deoxyhept-2E-Enoic Acid

    CAS:
    <p>Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.</p>
    Fórmula:C33H33FN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:540.62
  • Mibefradil

    CAS:
    <p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>
    Fórmula:C29H38FN3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:495.63
  • TAP311


    <p>TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).</p>
    Fórmula:C34H40F6N6O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:710.71
  • PDE4-IN-6


    <p>PDE4-IN-6: Potent PDE4 inhibitor, IC50 - 0.125μM (B), 0.43μM (D), anti-inflammatory, for arthritis research.</p>
    Fórmula:C25H20FNO5S
    Forma y color:Solid
    Peso molecular:465.49
  • 8-Hydroxychlorpromazine

    CAS:
    <p>8-Hydroxychlorpromazine is a metabolite of Chlorpromazine that can enhance the hyperglycemic response following glucose loading, suggesting a possible synergistic role in Chlorpromazine-induced glucose metabolism disorders. It holds potential for research into metabolic diseases.</p>
    Fórmula:C17H19ClN2OS
    Forma y color:Solid
    Peso molecular:334.864
  • DS44470011

    CAS:
    <p>DS44470011 is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) with oral bioavailability. It enhances the release of erythropoietin (EPO) from cells and is utilized in research related to renal anemia.</p>
    Fórmula:C21H19N3O4
    Forma y color:Solid
    Peso molecular:377.39
  • NAMPT activator-6

    CAS:
    <p>NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].</p>
    Fórmula:C17H21N5O3S
    Forma y color:Solid
    Peso molecular:375.45
  • Antidiabetic agent 5

    CAS:
    <p>Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1].</p>
    Fórmula:C17H15N3O4S
    Forma y color:Solid
    Peso molecular:357.38