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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 8626 productos de "Metabolismo"

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  • PDE4-IN-12


    <p>PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).</p>
    Fórmula:C34H35NO6
    Forma y color:Solid
    Peso molecular:553.64
  • 7PPD-Q

    CAS:
    <p>7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).</p>
    Fórmula:C19H24N2O2
    Forma y color:Solid
    Peso molecular:312.41
  • PF-07202954

    CAS:
    <p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>
    Fórmula:C22H23FN6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:438.45
  • Estradiol 3-glucuronide

    CAS:
    <p>Estradiol 3-glucuronide is an immunogen with antigenic properties. The antiserum induced in rabbits exhibits high affinity and specificity for Estradiol 3-glucuronide. This compound shows promise for use in research involving radioimmunoassay.</p>
    Fórmula:C24H32O8
    Forma y color:Solid
    Peso molecular:448.51
  • RO5101576

    CAS:
    <p>RO5101576 is a potent antagonist of LTB4 receptor.</p>
    Fórmula:C36H38O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:630.75
  • BPU17

    CAS:
    <p>BPU17 interacts with PHB1 and disrupts the PHB1-PHB2 interaction, causing slight mitochondrial dysfunction. This damage hinders transcription dependent on SRF/CArG-box, thereby inhibiting epithelial-mesenchymal transition (EMT) in retinal pigment epithelial cells (RPEs). BPU17 has demonstrated anti-fibrotic activity in vivo. It holds potential as a research agent for anti-angiogenic age-related macular degeneration (nAMD).</p>
    Fórmula:C12H13ClN2O2
    Forma y color:Solid
    Peso molecular:252.70
  • 3'-Hydroxy Repaglinide

    CAS:
    <p>'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.</p>
    Fórmula:C27H36N2O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:468.59
  • SHP2-IN-9


    <p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>
    Fórmula:C20H20FN3O2S
    Forma y color:Solid
    Peso molecular:385.46
  • Complex III-IN-2


    <p>Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.</p>
    Fórmula:C15H21ClN2O2S
    Forma y color:Solid
    Peso molecular:328.86
  • 2-Amino-5-methyl-5-hexenoic acid

    CAS:
    <p>2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.</p>
    Fórmula:C7H13NO2
    Forma y color:Solid
    Peso molecular:143.184
  • Etamicastat

    CAS:
    <p>Etamicastat can be used in the research of cardiovascular diseases.</p>
    Fórmula:C14H15F2N3OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:311.35
  • PF-00489791

    CAS:
    <p>PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.</p>
    Fórmula:C20H28N8O4S
    Pureza:99.97%
    Forma y color:Solid
    Peso molecular:476.55
  • Diethylumbelliferyl phosphate

    CAS:
    <p>Diethylumbelliferyl phosphate (DEUP) is a potent and selective inhibitor of cholesterol esterase that does not inhibit protein kinase A activity in vitro. It disrupts steroidogenesis by blocking cholesterol transport to mitochondria in steroidogenic cells, with an IC50 of 11.6 μM. This compound may also limit the absorption of dietary cholesterol.</p>
    Fórmula:C14H17O6P
    Forma y color:Solid
    Peso molecular:312.25
  • Oxythiamine diphosphate ammonium


    <p>Oxythiamin diphosphate ammonium is a potent inhibitor of transketolase (TK).</p>
    Forma y color:Solid
  • Anticancer agent 143

    CAS:
    <p>Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.</p>
    Fórmula:C19H15BrF2N3O6PS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:594.34
  • CAII-IN-3


    <p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>
    Fórmula:C18H18F2N4S
    Forma y color:Solid
    Peso molecular:360.42
  • RORγ-IN-2

    CAS:
    <p>RORγ-IN-2 (Compound 22) is an inhibitor of RORγ, with a Ki value of 16.6 nM for hRORγ. It is useful for research in IL-17-dependent autoimmune diseases.</p>
    Fórmula:C28H32F3N5O4S2
    Forma y color:Solid
    Peso molecular:623.71
  • Complex III-IN-1


    <p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>
    Fórmula:C14H20ClNO2S2
    Forma y color:Solid
    Peso molecular:333.9
  • NAZ2329

    CAS:
    <p>NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) &amp; hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.</p>
    Fórmula:C21H18F3NO4S3
    Forma y color:Soild
    Peso molecular:501.56
  • FXIa-IN-9

    CAS:
    <p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>
    Fórmula:C23H18Cl2F3N9O2
    Forma y color:Solid
    Peso molecular:580.35