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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8628 productos de "Metabolismo"

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  • ZK159222

    CAS:
    <p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>
    Fórmula:C32H48O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:512.72
  • 3-Oxochenodeoxycholic acid

    CAS:
    3-Oxochenodeoxycholic acid is an endogenous metabolite detectable in feces and may serve as a diagnostic marker for various diseases, including COVID-19.
    Fórmula:C24H38O4
    Peso molecular:390.556
  • Lipid PPz-2R1

    CAS:
    Lipid PPz-2R1 is an ionizable cationic lipid employed in crafting lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. LNPs with lipid PPz-2R1, encapsulating an mRNA reporter, target the lungs preferentially over the heart, liver, spleen, and kidneys in mice. Additionally, these LNPs, when encapsulating mRNA encoding phosphatase and tensin homolog (PTEN), enhance PTEN protein levels in PTEN-deficient Lewis lung carcinoma (LLC) cells. In an orthotopic murine LLC model, these Lipid PPz-2R1-containing LNPs, carrying PTEN mRNA, reduce tumor growth either when administered alone or alongside an antibody against programmed cell death protein 1 (PD-1).
    Fórmula:C48H94N2O4
    Peso molecular:763.27
  • AD012


    <p>AD012, a dual cACE/NEP inhibitor, leverages lenopril-tryptophan for potential anti-hypertensive and cardioprotective benefits.</p>
    Fórmula:C25H32N2O6
    Forma y color:Solid
    Peso molecular:456.53
  • Cephapirin lactone

    CAS:
    Cephapirinlactone is a metabolite of the antibiotic Cephapirin.
    Fórmula:C15H13N3O4S2
    Peso molecular:363.41
  • Nampt-IN-15

    CAS:
    Nampt-IN-15 (Example 3) is a Nampt inhibitor that exhibits cytotoxic effects on various cell lines, including BxPC-3, HepG2, L540cy, and MOLM-13. The respective IC50 values for these cell lines are 38.5 nM, 8 nM, 8.5 nM, and 7 nM.
    Fórmula:C24H30N4O2
    Forma y color:Solid
    Peso molecular:406.52
  • FXR agonist 12

    CAS:
    <p>FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.</p>
    Fórmula:C26H44O3
    Forma y color:Solid
    Peso molecular:404.626
  • trans-Doxercalciferol

    CAS:
    <p>trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.</p>
    Fórmula:C28H44O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:412.65
  • PDE4B/7A-IN-2

    CAS:
    <p>5-HT1A/5-HT7 antagonist; 5-HT1A Ki=8 nM, 5-HT7 Ki=451 nM; PDE4B IC50=80.4 μM, PDE7A IC50=151.3 μM; stronger than escitalopram.</p>
    Fórmula:C25H35N3O2
    Forma y color:Solid
    Peso molecular:409.56
  • Diacylglycerol acyltransferase inhibitor-1

    CAS:
    <p>Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.</p>
    Fórmula:C21H23N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:377.44
  • hDHODH-IN-10


    <p>hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.</p>
    Fórmula:C21H15ClF4N2O4
    Forma y color:Solid
    Peso molecular:470.8
  • RXR antagonist 1


    <p>RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.</p>
    Fórmula:C28H33F3N2O3
    Forma y color:Solid
    Peso molecular:502.57
  • Turoctocog alfa

    CAS:
    <p>Turoctocog alfa: recombinant FVIII from CHO cells for hemophilia A study.</p>
    Forma y color:Solid
  • CAII-IN-3


    <p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>
    Fórmula:C18H18F2N4S
    Forma y color:Solid
    Peso molecular:360.42
  • Rostratin A

    CAS:
    <p>Rostratin A, a disulfide from Exserohilum rostratum, is cytotoxic to HCT-116 cells with an IC50 of 8.5 μg/mL.</p>
    Fórmula:C18H24N2O6S2
    Forma y color:Solid
    Peso molecular:428.52
  • Nonsteroidal aromatase inhibitor 1


    <p>Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.</p>
    Fórmula:C22H16N4O2
    Forma y color:Solid
    Peso molecular:368.39
  • BMS-185354

    CAS:
    BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.
    Fórmula:C26H27NO3
    Forma y color:Solid
    Peso molecular:401.497
  • Omesdafexor

    CAS:
    <p>Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.</p>
    Fórmula:C34H43N3O3
    Forma y color:Solid
    Peso molecular:541.72
  • Ranosidenib

    CAS:
    <p>Ranolisib is an isocitrate dehydrogenase (IDH) inhibitor known for its antitumor activity.</p>
    Fórmula:C15H16F9N5O
    Forma y color:Solid
    Peso molecular:453.31
  • DH376

    CAS:
    <p>DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.</p>
    Fórmula:C31H28F2N4O3
    Forma y color:Solid
    Peso molecular:542.58