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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8625 productos de "Metabolismo"

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  • ERAP1 modulator-1

    CAS:
    <p>ERAP1 modulator-1 (Compound 1) is a regulator of endoplasmic reticulum aminopeptidase 1 (ERAP1) with an IC50 of less than 250 nM.</p>
    Fórmula:C23H23F3N2O5S
    Forma y color:Solid
    Peso molecular:496.5
  • APOL1-IN-2

    CAS:
    <p>APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1). It effectively reduces HEK293 cell death induced by APOL1 G2/G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2/G1/G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.</p>
    Fórmula:C28H30ClF3N4O5
    Forma y color:Solid
    Peso molecular:595.01
  • PPARγ agonist 15


    <p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>
    Fórmula:C21H16N4O3S2
    Forma y color:Solid
    Peso molecular:436.51
  • APL180

    CAS:
    <p>APL180 (L-4F) is an apolipoprotein A-I mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). It is applicable for cardiovascular disease research.</p>
    Fórmula:C114H156N24O28
    Forma y color:Solid
    Peso molecular:2310.6
  • Plipastatin A1

    CAS:
    <p>Plipastatin A1, a lipopeptide isolated from B.</p>
    Fórmula:C72H110N12O20
    Forma y color:Solid
    Peso molecular:1463.71
  • hCAI/II-IN-10


    <p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>
    Fórmula:C24H17Cl2N3O3S2
    Forma y color:Solid
    Peso molecular:530.446
  • cis-Vitamin K1

    CAS:
    <p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>
    Fórmula:C31H46O2
    Forma y color:Solid
    Peso molecular:450.70
  • ZG-2033

    CAS:
    <p>ZG-2033 (Compound 26) is an orally active HIF-2α agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.</p>
    Fórmula:C15H14N2O2S
    Forma y color:Solid
    Peso molecular:286.35
  • PPARγ agonist 16

    CAS:
    <p>PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.</p>
    Fórmula:C19H14BrNO4S
    Forma y color:Solid
    Peso molecular:432.29
  • Galactose 1-phosphate

    CAS:
    <p>Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways</p>
    Fórmula:C6H13O9P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:260.14
  • Hydroxycotinine

    CAS:
    <p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>
    Fórmula:C10H12N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:192.218
  • Calcium Channel antagonist 5

    CAS:
    <p>Calcium Channel antagonist5 (compound 32) is a calcium channel antagonist with a pIC50 of 5.50.</p>
    Fórmula:C17H18N2O6
    Forma y color:Solid
    Peso molecular:346.34
  • Adenosine 3',5'-diphosphate sodium salt

    CAS:
    <p>Adenosine 3',5'-diphosphate sodium inhibits hydroxysteroid sulfotransferases and studies SULT kinetics/structure.</p>
    Fórmula:C10H15N5NaO10P2
    Pureza:95%
    Forma y color:Solid
    Peso molecular:450.19
  • DSPE-PEG1000-R6H4


    <p>DSPE-PEG1000-R6H4 is a PEG compound comprised of DSPE and pH-responsive cell-penetrating peptide (R6H4), designed for pH-sensitive anti-cancer drug delivery. It is utilized in drug delivery applications.</p>
    Forma y color:Odour Solid
  • AK-4


    <p>AK-4 is an antidiabetic agent that functions as a mitochondrial uncoupler.</p>
    Fórmula:C21H14Cl2N2O4S
    Forma y color:Solid
    Peso molecular:461.32
  • LYP-IN-3


    <p>LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway</p>
    Fórmula:C35H27NO6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:589.66
  • BDM_92499


    <p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>
    Forma y color:Odour Solid
  • L-Isoleucyl-L-arginine

    CAS:
    <p>L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in</p>
    Fórmula:C12H25N5O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:287.36
  • Anticancer agent 232


    Anticanceragent 232 (compound 12f) is a sugar hybrid designed from 1-azide glycosides derived from d-glucose, d-galactose, and d-mannose. The IC50 values for this compound are 1.05 μM against MCF-7 cells and 18.03 μM for MDA-MB231 cells.
    Fórmula:C32H31BrN4O11
    Peso molecular:726.11727
  • 1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol

    CAS:
    <p>1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.</p>
    Fórmula:C12H14N2O4
    Pureza:99.49%
    Forma y color:Solid
    Peso molecular:250.25