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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8626 productos de "Metabolismo"

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  • Logo de CymitQuimica
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    3-O-Dihydro-p-coumaroyltohogenol

    <p>3-O-Dihydro-p-coumaroyltohogenol functions as a PTP1B inhibitor (IC50 = 6.27 μM), exhibiting anti-diabetic and anti-obesity activities.</p>
    Fórmula:C39H60O5
    Forma y color:Solid
    Peso molecular:608.89

    Ref: TM-T200206

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    ADP-specific glucokinase

    CAS:
    <p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>
    Forma y color:Solid

    Ref: TM-T89882

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    Phosphofructokinase

    CAS:
    <p>Phosphofructokinase, a crucial glycolytic enzyme, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolysis pathway. Its activity is inhibited by the binding of Phosphoenolpyruvate (PEP), which regulates the rate of glycolysis. Additionally, Phosphofructokinase is utilized in the measurement of fructose-6-phosphate (fructose-6-phosphate) levels.</p>
    Forma y color:Solid

    Ref: TM-T200040

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    IONIS PTP1BRx

    CAS:
    <p>IONIS PTP1BRx (ISIS 404173) acts as an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). This compound exhibits anti-diabetic properties, making it suitable for research into insulin resistance related to obesity and type 2 diabetes.</p>
    Forma y color:Solid

    Ref: TM-T200394

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    Antibacterial agent 237

    <p>Anti bacterial agent 237 (compound Ru-8) acts as a potent antibacterial agent against Staphylococcus aureus, exhibiting minimum inhibitory concentrations (MICs) ranging from 0.78 to 1.56 μg/mL. It works by disrupting bacterial cell membranes, altering their permeability, and inducing the production of reactive oxygen species, which leads to bacterial cell death without promoting resistance. Additionally, Anti bacterial agent 237 demonstrates low hemolytic toxicity towards rabbit erythrocytes and Raw 264.7 cells. It has shown significant antibacterial activity in models of skin wound infections in mice and larval infections by the greater wax moth, effectively combating Staphylococcus aureus infections.</p>
    Fórmula:C65H69Cl3N10RuS2
    Forma y color:Solid
    Peso molecular:1261.87

    Ref: TM-T89870

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    Imperatoxin A TFA

    <p>Imperatoxin A TFA, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, acts as an activator of Ca2+-release channels/ryanodine receptors (RyRs). It facilitates the influx of Ca2+ from the sarcoplasmic reticulum into the cell.</p>
    Fórmula:C148H254N58O45S6·xC2HF3O2
    Forma y color:Solid
    Peso molecular:3758.35 (free base)

    Ref: TM-TP2838

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    NAD Synthetase

    CAS:
    <p>NAD Synthetase is responsible for the final step in the synthesis of Nicotinamide Adenine Dinucleotide (NAD). The enzyme sourced from Escherichia coli exhibits Km values of 200 μM for NAD, 11 μM for ATP, and 0.65 μM for ammonia. Conversely, NAD Synthetase derived from yeast demonstrates Km values of 170 μM for NAD, 190 μM for ATP, and 64 μM for ammonia. This enzyme is applicable in enzymatic assays for ATP, ammonia, urea, or creatinine and can also be used in enzymatic recycling methods. Additionally, NAD Synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative disorders.</p>
    Forma y color:Solid

    Ref: TM-T200236

  • 6-Ethyl-2,7-dimethoxyjuglone
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    6-Ethyl-2,7-dimethoxyjuglone

    CAS:
    <p>6-Ethyl-2,7-dimethoxyjuglone is a metabolite isolated from freshwater fungi [1] .</p>
    Fórmula:C14H14O5
    Forma y color:Solid
    Peso molecular:262.26

    Ref: TM-T75462

  • Amastatin hydrochloride
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    Amastatin hydrochloride

    CAS:
    <p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>
    Fórmula:C21H39ClN4O8
    Forma y color:White To Off-White Powder
    Peso molecular:511.01

    Ref: TM-T19665

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    h15-LOX-2 inhibitor 2

    <p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>
    Fórmula:C22H30Cl2N6O3
    Forma y color:Solid
    Peso molecular:497.42

    Ref: TM-T200017

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    PBI-6DNJ

    <p>PBI-6DNJ, an oral multivalent glycosidase inhibitor, has a K i of 0.14 μM against mouse α-glucosidase and aids type 2 diabetes research.</p>
    Fórmula:C120H146N26O36
    Forma y color:Solid
    Peso molecular:2528.6

    Ref: TM-T74901

  • Menthol glucuronide
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    Menthol glucuronide

    CAS:
    <p>Menthol glucuronide is a metabolite of L-(-)-Menthol, the natural form of Methanol.</p>
    Fórmula:C16H28O7
    Forma y color:Solid
    Peso molecular:332.39

    Ref: TM-T33284

  • Revizinone
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    Revizinone

    CAS:
    <p>Revizinone is a novel selective phosphodiesterase inhibitor with IC50 values on this enzyme to 0.036 microM.</p>
    Fórmula:C26H29N5O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:459.54

    Ref: TM-T12611L

  • 9(R)-HODE cholesteryl ester
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    9(R)-HODE cholesteryl ester

    CAS:
    <p>9(R)-HODE cholesteryl ester, from atherosclerotic lesions, may form enzymatically or by lipid peroxidation; used as a chiral analysis standard.</p>
    Fórmula:C45H76O3
    Forma y color:Solid
    Peso molecular:665.1

    Ref: TM-T35843

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    Maurocalcine TFA

    <p>Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.</p>
    Fórmula:C156H270N56O46S6·xC2HF3O2
    Forma y color:Solid
    Peso molecular:3858.55 (free base)

    Ref: TM-TP2868

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    Epoxide hydrolase

    CAS:
    <p>Epoxide hydrolase, an enzyme responsible for catalyzing the reaction of epoxides with water to convert epoxy groups into diols, plays a crucial role in the metabolism of environmental pollutants and lipids. It is instrumental in detoxification, inflammatory responses, and regulating the health of the cardiovascular system. Additionally, Epoxide hydrolase is used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, which are important for the synthesis of chiral pharmaceutical molecules.</p>
    Forma y color:Solid

    Ref: TM-T200049

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    DSPE-PEG2000-F3

    <p>DSPE-PEG2000-F3 is a PEG compound composed of DSPE and the nucleolin-targeting peptide (F3). The F3 peptide can specifically bind to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG2000-F3 is applicable for drug delivery.</p>
    Forma y color:Odour Solid

    Ref: TM-TCL-01188

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    DSPE-PEG2000-R8

    <p>DSPE-PEG2000-R8 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (R8). It can be applied in drug delivery.</p>
    Forma y color:Odour Solid

    Ref: TM-TCL-01093

  • ESI1
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    ESI1

    <p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>
    Fórmula:C18H18ClN5O
    Forma y color:Solid
    Peso molecular:355.82

    Ref: TM-T200212

  • Abiraterone N-oxide
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    Abiraterone N-oxide

    CAS:
    <p>Abiraterone N-oxide is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>
    Fórmula:C24H31NO2
    Forma y color:Solid
    Peso molecular:365.51

    Ref: TM-T74685