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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8625 productos de "Metabolismo"

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  • Ingenol disoxate

    CAS:
    <p>Ingenol disoxate (LEO43204) is a compound for treating actinic keratosis, a natural Euphorbia peplus extract.</p>
    Fórmula:C28H37NO7
    Forma y color:Solid
    Peso molecular:499.6
  • XW-032


    <p>XW-032 is an apo-IDO1 inhibitor with an IC50 of 21 nM. In the CT26 syngeneic mouse model, XW-032 demonstrates significant in vivo antitumor efficacy with a TGI of 63%, showing potential for cancer research applications.</p>
    Forma y color:Odour Solid
  • Ferroleuton


    <p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>
    Fórmula:C13H16FeN2O2
    Forma y color:Solid
    Peso molecular:288.12
  • m-PEG8-DSPE


    <p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>
    Fórmula:C59H116NO17P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1142.52
  • Atocalcitol

    CAS:
    <p>Atocalcitol is a vitamin D analog. It also acts as an agonist of alcitriol receptor.</p>
    Fórmula:C32H46O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:494.71
  • GPX4-IN-16


    <p>GPX4-IN-16 ((R)-9i) is a potent inhibitor of GPX4 with a KD value of 20.4 nM, exhibiting cytotoxic properties and anticancer activity.</p>
    Fórmula:C29H24N4O3S2
    Forma y color:Solid
    Peso molecular:540.656
  • Naroparcil

    CAS:
    <p>Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.</p>
    Fórmula:C19H17NO4S2
    Pureza:98.71% - 99.88%
    Forma y color:Solid
    Peso molecular:387.47
  • Leuhistin

    CAS:
    Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.
    Fórmula:C11H19N3O3
    Pureza:98%
    Forma y color:White To Off-White Solid
    Peso molecular:241.29
  • Coformycin

    CAS:
    <p>Coformycin is a ribonucleoside antibiotic synergist and adenosine deaminase inhibitor.</p>
    Fórmula:C11H16N4O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:284.27
  • Propiverine N-oxide

    CAS:
    <p>Propiverine N-oxide is the primary metabolite of propiverine hydrochloride, and it influences bladder contraction and saliva secretion in miniature pigs.</p>
    Fórmula:C23H29NO4
    Forma y color:Solid
    Peso molecular:383.48
  • ICMT-IN-35


    <p>ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative.</p>
    Forma y color:Odour Solid
  • Sofosbuvir impurity E


    <p>Sofosbuvir impurity E, a less active byproduct, inhibits HCV RNA replication with potent anti-HCV effects.</p>
    Fórmula:C22H29FN3O9P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:529.45
  • α-Glucosidase-IN-83


    <p>α-Glucosidase-IN-83 (compound I-1) is a potent inhibitor of α-glucosidase, demonstrating an IC50 of 1.49 μg/mL. This compound effectively reduces blood glucose levels in vivo.</p>
    Fórmula:C25H20N4O6S
    Forma y color:Solid
    Peso molecular:504.514
  • PDE5-IN-10


    <p>PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,</p>
    Fórmula:C21H20N4O2
    Forma y color:Solid
    Peso molecular:360.41
  • BE2647


    <p>BE2647 is a selective inhibitor of the mitochondrial pyruvate carrier (MPC), with an EC50 of 70 nM. It exhibits good metabolic stability in mouse liver microsomes. BE2647 can be utilized in research related to metabolic diseases, metabolic-associated steatotic liver disease (MASLD), or metabolic-associated steatohepatitis (MASH).</p>
    Fórmula:C13H7Br2N3O2
    Forma y color:Solid
    Peso molecular:397.022
  • α-Glucosidase-IN-82


    <p>α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-glucosidase, with an IC50 value of 13.66 μM. Its inhibitory activity is 52 times greater than that of Acarbose.</p>
    Fórmula:C30H24N4O4
    Forma y color:Solid
    Peso molecular:504.536
  • Gluconapin

    CAS:
    <p>Gluconapin serves as a precursor to sulforaphane, an effective anticancer isothiocyanate. It has been found to reduce the increase in plasma triglycerides induced by corn oil consumption in mice.</p>
    Fórmula:C11H19NO9S2
    Forma y color:Solid
    Peso molecular:373.4
  • Ascorbate oxidase

    CAS:
    <p>Ascorbate oxidase, a REDOX enzyme, catalyzes ascorbic acid and oxygen to dehydroascorbic acid, regulating the extracellular matrix.</p>
    Forma y color:Solid
  • Geranyl pyrophosphate triammonium

    CAS:
    <p>Geranyl pyrophosphate, an intermediary for making cholesterol, terpenes, and others, forms from dimethylallyl and isopentenyl pyrophosphates.</p>
    Fórmula:C10H29N3O7P2
    Forma y color:Solid
    Peso molecular:365.304
  • TDO-IN-2


    <p>TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 μM. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.</p>
    Fórmula:C20H15N3O3
    Forma y color:Solid
    Peso molecular:345.11134