Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(74 productos)
- CETP(20 productos)
- Anhídrido carbónico(185 productos)
- Caseína quinasa(137 productos)
- DHFR(34 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(289 productos)
- FAAH(65 productos)
- FXR(59 productos)
- Factor Xa(83 productos)
- Ácido graso sintasa(36 productos)
- Ferroptosis(218 productos)
- GR(3 productos)
- GSNOR(4 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(145 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(34 productos)
- IDO(84 productos)
- LDL(8 productos)
- Lipasa(104 productos)
- Lípido(62 productos)
- Lipoxigenasa(132 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(38 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(168 productos)
- Fosfolipasa(82 productos)
- ROR(43 productos)
- Receptor de retinoides(28 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(43 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9054 productos de "Metabolismo"
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MTHFD2-IN-4
MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].Fórmula:C26H21F6N2O5Forma y color:SolidPeso molecular:555.45Diadenosine pentaphosphate pentasodium
CAS:Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.Fórmula:C20H24N10Na5O22P5Forma y color:SolidPeso molecular:1026.28Malate dehydrogenase
CAS:Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .Forma y color:SolidMK-8262
CAS:MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.Fórmula:C35H25F9N2O5Forma y color:SolidPeso molecular:724.58Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Fórmula:C22H24O11Forma y color:SolidPeso molecular:464.4H-Gly-Pro-Gly-NH2
CAS:<p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>Fórmula:C9H16N4O3Forma y color:SolidPeso molecular:228.25Teprotide
CAS:<p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>Fórmula:C53H76N14O12Forma y color:SolidPeso molecular:1101.26Dansylphenylalanine
CAS:<p>Dansylphenylalanine is a typical fluorescent analyte.</p>Fórmula:C21H22N2O4SForma y color:SolidPeso molecular:398.48DPP-4-IN-11
<p>DPP-4-IN-11 (compound 10) is an orally active DPP-4 inhibitor (IC50=2.75 μM) with anti-type 2 diabetes activity. This compound exerts its hypoglycemic effects by inhibiting the activity of α-glucosidase (IC50=3.02 μM) and α-amylase (IC50=3.3 μM).</p>Forma y color:Odour SolidDefensin HNP-2 human
CAS:<p>Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.</p>Fórmula:C147H223N43O37S6Forma y color:SolidPeso molecular:3377.03PROTAC CYP1B1 degrader-2
CAS:PROTAC CYP1B1 degrader-2 (compound PV2), a VHL (von Hippel - Landau) E3 ligase-based degrader of CYP1B1, exhibits a DC50 of 1.0 nM after 24 hours in A549/Taxol cells. Furthermore, it effectively inhibits the growth, migration, and invasion of A549/Taxol cells.Fórmula:C49H56ClN7O5S3Forma y color:SolidPeso molecular:954.6613C C16 Sphingomyelin (d18:1/16:0)
CAS:<p>'13C-enriched C16 Sphingomyelin is a standard for quantifying C16 sphingomyelin by MS. Common in eggs; less in brain/milk; interacts with cholesterol.'</p>Fórmula:C39H79N2O6PForma y color:SolidPeso molecular:704.035CooP
CAS:<p>CooP is a nonapeptide targeting glioblastoma. It binds to FABP3 for chemotherapy delivery.</p>Fórmula:C32H57N9O11SForma y color:SolidPeso molecular:775.91H-Ile-Pro-Pro-OH hydrochloride
CAS:<p>H-Ile-Pro-Pro-OH HCl, milk peptide, blocks ACE with 5 μM IC50. Antihypertensive.</p>Fórmula:C16H28ClN3O4Forma y color:SolidPeso molecular:361.86Fmoc-Ile-Ser(psi(Me,Me)pro)-OH
CAS:<p>Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide.</p>Fórmula:C27H32N2O6Forma y color:SolidPeso molecular:480.55α-Glucosidase-IN-54
CAS:<p>α-Glucosidase-IN-54 (compound 2) functions as an α-glucosidase inhibitor, exhibiting an IC 50 value of 0.011 mM, and is derived from Syzygium jambos (L.). This compound is employed in diabetes research [1].</p>Fórmula:C24H36O3Forma y color:SolidPeso molecular:372.54HLF1-11
CAS:<p>HLF1-11: human lactoferrin peptide, antimicrobial, inhibits MPO, steers monocytes to macrophages, boosts immunity.</p>Fórmula:C56H95N25O14SForma y color:SolidPeso molecular:1374.58N,S-Bis-Fmoc-Glutathione
CAS:<p>N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].</p>Fórmula:C40H37N3O10SForma y color:SolidPeso molecular:751.8Methionylserine
CAS:<p>Methionylserine (H-MET-SER-OH), a dipeptide, binds hPEPT1 (Km 0.2 mM), inhibits ACE, used in hypertension research.</p>Fórmula:C8H16N2O4SForma y color:SolidPeso molecular:236.29Tianeptine Metabolite MC5 sodium
CAS:<p>Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activation</p>Fórmula:C19H20ClN2O4S·NaForma y color:SolidPeso molecular:430.88Glycyllysine
CAS:<p>Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.</p>Fórmula:C8H17N3O3Forma y color:SolidPeso molecular:203.24SHP2-IN-37
SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 μM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 μM and 0.67 μM, respectively.Fórmula:C19H22Cl2N4O2SForma y color:SolidPeso molecular:440.084053-Oxocholic acid
CAS:3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Fórmula:C24H38O5Pureza:99.44%Forma y color:SolidPeso molecular:406.56NDH-1 inhibitor-1
CAS:NDH-1 inhibitor-1 is an effective NDH-1 inhibitor, which can inhibit bovine SMP (mitochondrial granules), potato SMP and Escherichia coli, with pI50 values of <Fórmula:C20H19NO3Pureza:99.91%Forma y color:SolidPeso molecular:321.37Zabicipril HCl
CAS:<p>Zabicipril HCl（S 9650） is a potent angiotensin-converting enzyme inhibitor.</p>Fórmula:C23H33ClN2O5Pureza:99.66%Forma y color:SoildPeso molecular:452.97PKM2 inhibitor G
CAS:<p>PKM2 inhibitor G is a inhibitor of pyruvate kinase.</p>Fórmula:C16H15NO3SPureza:99.89%Forma y color:SoildPeso molecular:301.36Nicotinic Acid Adenine Dinucleotide
CAS:Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthaseFórmula:C21H26N6O15P2Forma y color:SoildPeso molecular:664.41N-Desbutyl Dronedarone-d7 HCl
N-Desbutyl Dronedarone-d7 HCl is the deuterium-labelled isomer of N-Desbutyl Dronedarone HCl, used for isotope tracing. N-Desbutyl Dronedarone is a metabolite of the antiarrhythmic drug Dronedarone.Fórmula:C27H30D7ClN2O5SForma y color:SolidPeso molecular:544.15Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Fórmula:C4H5NO4SForma y color:SolidPeso molecular:163.15Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Fórmula:C29H49N7NaO17P3SForma y color:SolidPeso molecular:915.71GSK-3β/CK-1δ-IN-1
GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.Fórmula:C22H17F3N4OForma y color:SolidPeso molecular:410.39PKM2-IN-10
PKM2-IN-10 is a PKM2 inhibitor. It effectively suppresses the proliferation of A549 and HCC1833 cell lines with IC50 values of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 demonstrates antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. It is applicable for research in lung cancer.Fórmula:C21H15F4N5Forma y color:SolidPeso molecular:413.126361-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS:1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.Fórmula:C12H14N2O4Pureza:99.49%Forma y color:SolidPeso molecular:250.25Lysylcysteine TFA
Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.Fórmula:C13H21F6N3O7SForma y color:SolidPeso molecular:477.10044Prolylglutamic acid
CAS:<p>Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.</p>Fórmula:C10H16N2O5Forma y color:SolidPeso molecular:244.24SY-640
CAS:SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.Fórmula:C11H13NO3Pureza:99.51% - 99.66%Forma y color:SolidPeso molecular:207.23IDO1/TDO-IN-8
<p>IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.</p>Fórmula:C17H14N2SForma y color:SolidPeso molecular:278.37Casein Kinase 2 Substrate Peptide
CAS:<p>CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.</p>Fórmula:C45H73N19O24Forma y color:SolidPeso molecular:1264.17hCES2A-IN-2
hCES2A-IN-2 (compound 14n) is an orally active, highly specific, irreversible, covalent inhibitor of hCES2A with an IC50 of 0.04 nM. It targets and covalently binds to the catalytic serine residue (Ser-228) of hCES2A. hCES2A-IN-2 can significantly mitigate irinotecan-induced gastrointestinal toxicity (ITGT) without diminishing the antitumor efficacy of irinotecan in tumor-bearing mice.Forma y color:Odour SolidCasein kinase 1δ-IN-9
CAS:<p>Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.</p>Fórmula:C15H12ClN3Pureza:99.93%Forma y color:SolidPeso molecular:269.731-Methylisatin
CAS:Compound 2058-74-4, with CAS No. 2058-74-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 2058-74-4 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H7NO2Pureza:99.71%Forma y color:Orange To Brownish Crystalline PowderPeso molecular:161.16CK1-IN-4
CK1-IN-4 (Compound 59) is an inhibitor of casein kinase CK1δ with an IC50 of 2.74 μM. It exhibits neuroprotective activity in SH-SY5Y cells treated with Ethacrynic acid.Forma y color:Odour Solid(5S)-Neosamine C
CAS:(5S)-Neosamine C, an aminocyclic alcohol antibiotic derived from microbial secondary metabolites, possesses a cyclized structure and is utilized in the biosynthesis of Neomycins.Fórmula:C6H14N2O4Forma y color:SolidPeso molecular:178.19DPTIP
CAS:<p>DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.</p>Fórmula:C21H18N2O3SPureza:99.88%Forma y color:SolidPeso molecular:378.44H-Met-Val-OH
CAS:H-Met-Val-OH is a dipeptide inhibiting FMO1 and FMO3 and promoting neurite outgrowth, relevant for neuroregenerative and enzymatic modulation studies.Fórmula:C10H20N2O3SForma y color:SolidPeso molecular:248.34N1,N12-Diacetylspermine dihydrochloride
CAS:<p>Diacetylspermine 2HCl, a diacetylated Spermine, is a cancer biomarker linked to the disease's up-regulation.</p>Fórmula:C14H32Cl2N4O2Pureza:98%Forma y color:SolidPeso molecular:359.34Nucleocidin
CAS:<p>Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.</p>Fórmula:C10H13FN6O6SPureza:98%Forma y color:SolidPeso molecular:364.31D-Threonine
CAS:<p>D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.</p>Fórmula:C4H9NO3Pureza:≥98%Forma y color:SolidPeso molecular:119.121,1,3-Tribromoacetone
CAS:<p>1,1,3-Tribromoacetone (1,1,3-tribromo-2-propanone) is an impurity of methotrexate.</p>Fórmula:C3H3Br3OPureza:98%Forma y color:SolidPeso molecular:294.77FABP4-IN-3
<p>FABP4-IN-3 (Compound C3) is a highly selective inhibitor of FABP4, with an inhibition constant (Ki) of 25 ± 3 nM for FABP4 and a Ki of 15.03 μM for FABP3, showcasing a selectivity factor of 601 times over FABP3. It also demonstrates metabolic stability and potent anti-inflammatory activity in cells, making it a promising candidate for research in metabolic disorders, cardiac dysfunction, and inflammation-related diseases.</p>Fórmula:C20H16ClNO2Peso molecular:337.08696α-Amylase/α-Glucosidase-IN-12
α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase, with IC50 values of 34.52 nM and 24.62 nM, respectively. This inhibitor is designed based on [triazolo[4,3-b][1,2,4]triazine and holds potential for diabetes research.Fórmula:C19H13F3N6OSPeso molecular:430.08236Transketolase-IN-5
Transketolase-IN-5 (compound 6ba) is an inhibitor of transketolase. It exhibits herbicidal activity against Amaranthus retroflexus, Setaria viridis, and Digitaria sanguinalis.Fórmula:C20H24ClN5OPeso molecular:385.16694Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Fórmula:C26H28N4O6S2Peso molecular:556.14503Hexokinase II VDAC binding domain peptide, cell-permeable
HexokinaseIIVDACbinding domain peptide (Hxk2VBD peptide) is a cell-permeable peptide derived from the hexokinase II VDAC binding domain. This peptide inhibits the mitochondrial localization of hexokinase 2 (HXK2) and also suppresses neurotrophic factor-induced axon growth.Fórmula:C188H291N53O40S2Peso molecular:3995.18073Carbonic anhydrase/AChE-IN-2
<p>Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), with inhibition efficiencies (Ei) of 8.54 nM, 13.54 nM, and 5.21 nM, respectively.</p>Fórmula:C17H12BrF3O2Peso molecular:383.99728α-Glucosidase-IN-65
<p>α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.</p>Fórmula:C15H14N2O6Peso molecular:318.08519GZ22-4
<p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>Fórmula:C88H126F3N6NaO24S4Peso molecular:1858.75561FXIIa-IN-4
<p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.</p>Fórmula:C11H9FN4O3Peso molecular:264.06587LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Antibacterial agent 218
<p>Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.</p>Fórmula:C30H24N4OSPeso molecular:488.16708α-Glucosidase-IN-49
<p>α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.</p>Fórmula:C21H13F3N4O3S3Peso molecular:522.01019α-Glucosidase-IN-46
<p>α-Glucosidase-IN-46 is a potent inhibitor of α-glucosidase, with an IC50 of 26.0 μM. This compound is applicable in the research of Type 2 diabetes.</p>Fórmula:C35H32N4O5Peso molecular:588.23727LYP-8
<p>LYP-8 is a potent NAMPT degrader that achieves a maximum degradation rate of 97% in NAMPT within SKOV-3 cells at a concentration of 0.5 μM. LYP-8 also demonstrates anticancer activity both in vitro and in vivo.</p>Fórmula:C56H74N8O10SPeso molecular:1050.52486hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.06553IDO1-IN-24
IDO1-IN-24 (compound 2c) inhibits the production of IDO1 during cell assays, with an IC50 value of 17 μM.Fórmula:C18H22N2O4Peso molecular:330.15796AChE/BChE-IN-17
<p>AChE/BChE-IN-17 (compound 8m) is a potent inhibitor of AChE and BChE, displaying IC50 values of 125.06 nM and 119.68 nM, respectively. Additionally, AChE/BChE-IN-17 inhibits α-glucosidase, with an IC50 of 41050 nM.</p>Fórmula:C28H25N3O4Peso molecular:467.18451CTL26
CTL26 is an effective, orally active α-glucosidase inhibitor, with an IC50 value of 2.81 µM, demonstrating antidiabetic properties.Fórmula:C25H18N6O3SPeso molecular:482.11611α-Amylase/α-Glucosidase-IN-11
<p>α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazoline-indigo hybrid with notable antidiabetic properties. It acts as a competitive inhibitor of the key digestive enzymes α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM). Additionally, it does not penetrate the blood-brain barrier.</p>Fórmula:C33H40ClN5O5Peso molecular:621.2718α-Glucosidase-IN-60
α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.Fórmula:C23H14N2O5Peso molecular:398.09027MPO-IN-6
MPO-IN-6 (compound ADC) is an electrophilic agent with excellent antioxidant and anti-inflammatory properties. It acts as an inhibitor of myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD), with IC50 values of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 may serve as a potential cardiovascular protective agent.Fórmula:C16H12N2O6Peso molecular:328.06954SGK1-IN-3 hydrochloride
<p>SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the β-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.</p>Fórmula:C23H21Cl3N6O3SPeso molecular:566.04614α-Glucosidase-IN-58
α-Glucosidase-IN-58 (Compound 6d) is an α-glucosidase inhibitor with an IC50 of 1.47 μM.Fórmula:C22H13F3N2OSPeso molecular:410.07007Butyryl-Coenzyme A trisodium
Butyryl-Coenzyme A (trisodium) is a microbial metabolite that can be synthesized into butyric acid or butyrate.Fórmula:C25H39N7Na3O17P3SPeso molecular:903.10291PR280
<p>PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.</p>Fórmula:C27H49NO4Peso molecular:451.36616Conagenin
CAS:Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.Fórmula:C10H19NO6Pureza:98%Forma y color:SolidPeso molecular:249.26Triornicin
CAS:Triornicin is a siderophore and tumor inhibitory factor isolated from Epicoccum purpurascens similar in structure to desferricoprogen.Fórmula:C31H50N6O12Pureza:98%Forma y color:SolidPeso molecular:698.76Deoxyadenosine diphosphate sodium
CAS:Deoxyadenosine diphosphate sodium is a diphosphate nucleoside featuring deoxyadenosine as its nucleoside component. It plays a role in the synthesis and repair of DNA. Deoxyadenosine diphosphate sodium acts as an inhibitor of polynucleotide phosphorylase, thereby interfering with the polymerization of ADP and CDP.Fórmula:C10H12N5Na3O9P2Forma y color:SolidPeso molecular:477.15Cyperine
CAS:Cyperine is a useful organic compound for research related to life sciences. The catalog number is T125020 and the CAS number is 33716-82-4.Fórmula:C15H16O4Forma y color:SolidPeso molecular:260.289(+)-Menthofuran
(+)-Menthofuran is a useful organic compound for research related to life sciences and the catalog number is T125544.Fórmula:C10H14OForma y color:SolidPeso molecular:150.221Cefetamet Hydrochloride
CAS:Cefetamet is a potent antibiotic to treat respiratory and urinary tract infections.Fórmula:C14H16ClN5O5S2Pureza:98%Forma y color:SolidPeso molecular:433.89Triethyl phosphate
CAS:Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".Fórmula:C6H15O4PPureza:98%Forma y color:Clear LiquidPeso molecular:182.16Leucomyosuppressin
CAS:Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.Fórmula:C59H84N16O15Pureza:98%Forma y color:SolidPeso molecular:1257.418Phytosterols
CAS:Phytosterols found in algae have anti-cancer activity and are used in the study of cardiovascular diseases and cancer.Pureza:98%Forma y color:SolidERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Fórmula:C22H22N2O4SForma y color:SolidPeso molecular:410.49Largazole
CAS:Largazole is a potent and selective histone deacetylase (HDAC) inhibitor and antiproliferative agent from Symploca.Fórmula:C29H42N4O5S3Forma y color:SolidPeso molecular:622.86Probestin
CAS:Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.Fórmula:C26H38N4O6Pureza:98%Forma y color:SolidPeso molecular:502.60BtGH84 Activator I
CAS:BtGH84 Activator I is a BtGH84 activator. It is the small molecule activator of a glycoside hydrolase.Fórmula:C10H10N2OForma y color:SolidPeso molecular:174.20COMT-IN-2
<p>COMT-IN-2 (compound 9) is the most potent inhibitor of COMT, exhibiting selective inhibition for brain (IC50=24 nM) and liver (IC50=81 nM) MB-COMT compared to the liver S-COMT isoform (IC50=620 nM).</p>Forma y color:Odour SolidFexarene
CAS:<p>Fexarene is a non-steroidal FXR agonist.</p>Fórmula:C32H33NO3Pureza:98%Forma y color:SolidPeso molecular:479.62Evinacumab
CAS:<p>Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.</p>Pureza:100% (SEC-HPLC) - 99.43% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5 kDaLipstatin
CAS:Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.Fórmula:C29H49NO5Pureza:98%Forma y color:SolidPeso molecular:491.7Campestanol
CAS:Campestanol is a natural plant sterol from Brassica campestris.Fórmula:C28H50OForma y color:SolidPeso molecular:402.71PDE1-IN-8
<p>PDE1-IN-8 (Compound 3f) acts as an inhibitor of PDE1, with an IC50 of 11 nM. It hinders cAMP and cGMP signaling pathways, impeding the differentiation and proliferation of cells into myofibroblasts, and demonstrates antifibrotic effects in the Bleomycin-induced rat model of pulmonary fibrosis.</p>Fórmula:C17H11Cl2N3OS2Forma y color:SolidPeso molecular:408.32BVT-2733 hydrochloride
CAS:BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Fórmula:C17H22Cl2N4O3S2Forma y color:SolidPeso molecular:465.42DJ-53
<p>DJ-53 (compound 68) is an orally active, phenyl-quinoline-based soluble epoxide hydrolase inhibitor.</p>Forma y color:Odour SolidLY 135114
CAS:LY 135114 is a metabolite of LY 195448, which is a phenethanolamine with anti-tumour activity.Fórmula:C20H26N2O3Pureza:98%Forma y color:SolidPeso molecular:342.43MNI caged kainic acid
CAS:<p>Generates large inward currents at resting membrane potential</p>Fórmula:C19H23N3O6Pureza:98%Forma y color:SolidPeso molecular:389.40EC1454
CAS:EC1454 is an anti-tumor compound.Fórmula:C65H98N16O34SPureza:98%Forma y color:SolidPeso molecular:1679.63Enpp-1-IN-21
CAS:Enpp-1-IN-21 (compound 4g) is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC50 values of 0.45 μM for ENPP1 and 0.19 μM for ENPP3.Fórmula:C21H16F3NO5SForma y color:SolidPeso molecular:451.42Rovicurt
CAS:<p>Rovicurt is use as a pesticide.</p>Fórmula:C40H45Cl2NO7Pureza:98%Forma y color:SolidPeso molecular:722.7hDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Fórmula:C18H20N2O2Forma y color:SolidPeso molecular:296.36Anirolac
CAS:<p>Anirolac is a nonsteroidal anti-inflammatory agent.</p>Fórmula:C16H15NO4Pureza:98%Forma y color:SolidPeso molecular:285.29NPE-caged-proton
CAS:Generates rapid acidifications down to pH 2Fórmula:C8H9NNaO6SPureza:98%Forma y color:SolidPeso molecular:270.22isomer-GAT 107
CAS:isomer-GAT 107 ((-)GAT 107) is an inactive isomer of (+)GAT 107.Fórmula:C18H17BrN2O2SPureza:99.33%Forma y color:SoildPeso molecular:405.31MP 518
CAS:<p>MP 518 is a PDE inhibitor with antihypertensive properties. It prevents the degradation of cAMP, leading to increased ICa levels, and counteracts the effects of β-adrenergic stimulation, resulting in vasodilation.</p>Fórmula:C10H11ClN2O2Forma y color:SolidPeso molecular:226.66Diphenamid
CAS:<p>Diphenamid is a chemical compound from the group of acetamides and a herbicide. The effect is based on the inhibition of acetyl-CoA carboxylase.</p>Fórmula:C16H17NOPureza:98%Forma y color:White Diphenamid Is A Colorless To Off-White Crystals Used As An HerbicidePeso molecular:239.31Bromacil
CAS:Bromacil, a substituted uracil herbicide used worldwide, is not readily biodegradable and therefore has consequences to the environment.Fórmula:C9H13BrN2O2Forma y color:SolidPeso molecular:261.12Fibrostatin C
CAS:Fibrostatin C is an inhibitor of prolyl 4-hydroxylase. It is produced by Streptomyces catenulae subsp.Fórmula:C18H19NO8SForma y color:SolidPeso molecular:409.41(R)-AS-1
CAS:(R)-AS-1 is a selective positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2), with an EC50 of 11 nM. At doses of 60 and 90 mg/kg, (R)-AS-1 enhances spontaneous locomotor activity in mice. It demonstrates anticonvulsant properties in mouse seizure models induced by maximal electroshock (MES), pentylenetetrazole (PTZ), or electric current stimulation (32 or 44 mA), with ED50 values of 66.3, 36.3, 15.6, and 41.6 mg/kg, respectively. This compound is applicable in neurological disease research.Fórmula:C14H16N2O3Forma y color:SolidPeso molecular:260.29Dactylocycline A
CAS:<p>Dactylocyclines A: novel antibiotic from Dactylosporangium, effective against tetracycline-resistant microbes.</p>Fórmula:C31H40ClN3O13Pureza:98%Forma y color:SolidPeso molecular:698.11tetranor-12(R)-HETE
CAS:<p>Corneal metabolism of 12(R)-HETE yields 8(R)-HHxTrE via β-oxidation, losing four carbons from C-1.</p>Fórmula:C16H26O3Forma y color:SolidPeso molecular:266.381Endocrocin
CAS:Endocrocin is a useful organic compound for research related to life sciences. The catalog number is T124800 and the CAS number is 481-70-9.Fórmula:C16H10O7Forma y color:SolidPeso molecular:314.249SHP2-IN-34
CAS:SHP2-IN-34 (compound A8) is a phenylurea SHP2 inhibitor with anti-cancer properties. It significantly suppresses tumor growth in CT26 mouse models.Fórmula:C23H25Cl2N7OSForma y color:SolidPeso molecular:518.46Rubratoxin B
CAS:Rubratoxin B is a mycotoxin that causes hypoglycemia and fatty liver and has exhibited anticancer activity.Fórmula:C26H30O11Pureza:98%Forma y color:Long Lathes; Hexagonal Plates From Amyl Acetate SolidPeso molecular:518.511,3-Dipalmitoleoyl-rac-glycerol
CAS:1,3-Dipalmitoleoyl-rac-glycerol: a diacylglycerol inhibiting yeast α-glucosidase over rat's (IC50s: 4.45 vs 9326.5 μM). Used to study membrane potentials.Fórmula:C35H64O5Forma y color:SolidPeso molecular:564.892Methylbenzethonium chloride hydrate
CAS:Methylbenzethonium chloride hydrate exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Additionally, it is utilized as a preservative in cosmetics and pharmaceutical formulations to inhibit microbial growth.Fórmula:C28H46ClNO3Forma y color:SolidPeso molecular:480.124-Hydroxybenzoic acid-d4
CAS:4-Hydroxybenzoicacid-d4 is a deuterated form of 4-Hydroxybenzoicacid, which is a phenolic derivative of benzoic acid. It is effective in inhibiting most Gram-positive bacteria and some Gram-negative bacteria with an IC50 of 160 μg/mL.Fórmula:C7H6O3Forma y color:SolidPeso molecular:142.15Purpactin A
CAS:<p>Purpactin A is a useful organic compound for research related to life sciences. The catalog number is T126026 and the CAS number is 133806-59-4.</p>Fórmula:C23H26O7Forma y color:SolidPeso molecular:414.454Etodolac Acyl Glucuronide
CAS:<p>Etodolac acyl glucuronide is an NSAID metabolite formed by UGT1A9, UGT1A10, and UGT2B7 glucuronidation.</p>Fórmula:C23H29NO9Forma y color:SolidPeso molecular:463.4831,2,3,6,7,8-Hexachlorodibenzofuran
CAS:1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.Fórmula:C12H2Cl6OForma y color:SolidPeso molecular:374.86Ciwujianoside C2
CAS:Ciwujianoside C2 is a useful organic compound for research related to life sciences. The catalog number is T126337 and the CAS number is 114892-56-7.Fórmula:C60H94O26Forma y color:SolidPeso molecular:1231.39Porfimer Sodium
CAS:Porfimer sodium, a sodium salt with photodynamic properties, targets tumor cells and induces cytotoxicity with 630 nm laser activation.Fórmula:C68H74N8O11Forma y color:SolidPeso molecular:1179.385(±)13(14)-EpDPA
CAS:<p>Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.</p>Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.495KOTX1
CAS:KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Fórmula:C17H16FN3O2Forma y color:SolidPeso molecular:313.33(Iso)-Dehydroemetine
CAS:<p>(Iso)-Dehydroemetine (Dehydroisoemetine, (+/-)-) is a compound with antispasmolytic effect on smooth muscle.</p>Fórmula:C29H38N2O4Pureza:98.26% - 98.31%Forma y color:SoildPeso molecular:478.62Meproscillarin
CAS:<p>Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.</p>Fórmula:C31H44O8Forma y color:SolidPeso molecular:544.68(±)7(8)-EpDTE
CAS:(±)7(8)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid .Fórmula:C22H34O3Forma y color:SolidPeso molecular:346.511MeIQx
CAS:<p>MeIQx, a carcinogenic compound in cooked fish/meat, triggers DNA-reactive metabolites and rat tumors.</p>Fórmula:C11H11N5Forma y color:SolidPeso molecular:213.2444-hydroxy Valsartan
CAS:<p>4-hydroxy Valsartan, a key valsartan metabolite, curbs epinephrine and collagen-caused platelet clumping, not ADP's.</p>Fórmula:C24H29N5O4Forma y color:SolidPeso molecular:451.527Monononadecanoin
CAS:Monononadecanoin is a lipid compound known for its anti-inflammatory and antioxidant properties. It is frequently used in skincare products as a moisturizer and skin-repairing agent. Additionally, Monononadecanoin serves as a flavor enhancer and preservative in food additives.Fórmula:C22H46O5Forma y color:SolidPeso molecular:390.6ochracin
CAS:<p>(S)-(+)-ochracin (8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one) is a marine derived natural products found in Helicascus kanaloanus.</p>Fórmula:C10H10O3Pureza:90% - 99.79%Forma y color:SoildPeso molecular:178.18SK&F 104976
CAS:SK&F 104976 is a 32-carboxylic acid derivative of lanosterol. It was found to be a potent lanosterol 14 alpha-demethylase (14 alpha DM) inhibitor.Fórmula:C31H50O3Pureza:98%Forma y color:SolidPeso molecular:470.73Betulin ditosylate
CAS:<p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>Fórmula:C44H62O6S2Forma y color:SolidPeso molecular:751.09UK-383367
CAS:<p>UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs.</p>Fórmula:C15H24N4O4Pureza:>99.99%Forma y color:SolidPeso molecular:324.38Benzoic acid (Standard)
CAS:<p>Benzoic acid (Standard) is a standard substance for quantitative analysis.Benzoic acid (Dracylic acid) is an aromatic alcohol and common additive.</p>Fórmula:C7H6O2Pureza:99.99%Forma y color:White Solid Monoclinic Tablets Plates LeafletsPeso molecular:122.12H-Tyr-Ala-OH
CAS:<p>Tyrosylalanine (H-Tyr-Ala-OH), a dipeptide comprising L-tyrosine and L-alanine, is referenced in studies [1] [2].</p>Fórmula:C12H16N2O4Pureza:99.74%Forma y color:SolidPeso molecular:252.27Prenisteine
CAS:<p>Prenisteine is a bioactive chemical.</p>Fórmula:C8H15NO2SForma y color:SolidPeso molecular:189.2752,3,4,5-Tetrachlorophenol
CAS:2,3,4,5-Tetrachlorophenol, a γ-lindane byproduct, is toxic to minnows, trout (LC50: 0.496, 0.304 mg/L).Fórmula:C6H2Cl4OForma y color:SolidPeso molecular:231.88Mesembrenone
CAS:<p>Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.</p>Fórmula:C17H21NO3Pureza:98%Forma y color:SolidPeso molecular:287.35Leukotriene C4 methyl ester
CAS:LTC4, made by neutrophils and others via LTC4 synthase, causes smooth muscle contractions and is involved in asthma/allergic responses.Fórmula:C31H49N3O9SForma y color:SolidPeso molecular:639.81Uricosuric agent-1
CAS:<p>Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- is a compound used for antiviral activity determinations.</p>Fórmula:C19H16O5Pureza:99.88%Forma y color:SolidPeso molecular:324.33(±)10(11)-DiHDPA
CAS:(±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid .Fórmula:C22H34O4Forma y color:SolidPeso molecular:362.51Sandosaponin A
CAS:Sandosaponin A, an olean-12-ene-type triterpene oligoglycoside, is isolated from kidney bean, the seed of Phaseolus vulgaris L.Fórmula:C48H76O19Pureza:98%Forma y color:SolidPeso molecular:957.11Leukotriene B3
CAS:<p>LTB3, a LTA3-derived leukotriene, matches LTB4's inflammation effect but is 5x weaker in neutrophil chemotaxis.</p>Fórmula:C20H34O4Forma y color:SolidPeso molecular:338.488Nodularin
CAS:<p>Nodularin from N. spumigena is a hepatotoxic pentapeptide that inhibits PP1 and PP2A with IC50s of 1.8 nM and 0.026 nM, respectively.</p>Fórmula:C41H60N8O10Forma y color:SolidPeso molecular:824.977Linoleoyl-L-carnitine (chloride)
CAS:Linoleoyl-L-carnitine, a natural acylcarnitine, rises in mouse liver post high-dose isoniazid (200 mg/kg).Fórmula:C25H46ClNO4Forma y color:SolidPeso molecular:460.1Osteogenic Growth Peptide, OGP
CAS:<p>OGP, a natural 14-mer serum peptide at μM levels, is crucial for osteogenic response to bone injury.</p>Fórmula:C68H110N22O18Pureza:98%Forma y color:SolidPeso molecular:1523.74SMS2-IN-1
CAS:<p>SMS2-IN-1: potent SMS2 inhibitor; IC50: 6.5 nM, Kd: 37 nM; 150x selectivity over SMS1.</p>Fórmula:C34H37F6N3O5Pureza:98%Forma y color:SolidPeso molecular:681.67SBI993
CAS:<p>SBI993, a SBI-477 analog, confirms MondoA gene action in vivo and lowers muscle TAG and liver fat.</p>Fórmula:C23H23N3O5SPureza:99.20%Forma y color:SolidPeso molecular:453.51Alphitonin
CAS:<p>Alphitonin: a flavonoid in L. leptolepis wood, metabolized from quercetin by E. ramulus in the gut.</p>Fórmula:C15H12O7Forma y color:SolidPeso molecular:304.25(-)-OPC-51803
CAS:(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.Fórmula:C26H32ClN3O2Pureza:98.73% - 99.59%Forma y color:SoildPeso molecular:454Hydroxydehydro Nifedipine Carboxylate
CAS:Hydroxydehydro nifedipine carboxylate is a metabolite of nifedipine .1Fórmula:C16H14N2O7Forma y color:SolidPeso molecular:346.295Oseltamivir acid methyl ester hydrochloride
CAS:<p>Oseltamivir acid methyl ester hydrochloride, a precursor to oseltamivir, is converted by CES1.</p>Fórmula:C15H27ClN2O4Pureza:98.78%Forma y color:SoildPeso molecular:334.843-keto Fusidic Acid
CAS:<p>3-keto Fusidic acid (3-keto FA) is an active metabolite of the antibiotic fusidic acid .13-keto FA is active againstM. tuberculosis(MIC99= 1.25 μM).</p>Fórmula:C31H46O6Forma y color:SolidPeso molecular:514.70317(R)-HETE
CAS:<p>Kidney sodium transport is partly controlled by 17-HETE, a CYP450 metabolite of arachidonic acid, with the (S) enantiomer inhibiting ATPase at 2 μM.</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.473Thymus peptide C
CAS:<p>Thymus peptide C, a hormonal drug derived from the thymus glands of young calves, acts as a substitute for the physiological functions of the thymus.</p>Fórmula:NAPureza:98%Forma y color:SolidPeso molecular:N/A16(S)-HETE
CAS:16(S)-HETE, a CYP450 byproduct of arachidonic acid, inhibits kidney tubule ATPase by 60% at 2 μM upon angiotensin II trigger.Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.473Glycidamide
CAS:<p>Glycidamide is a carcinogen and metabolite of acrylamide that induces DNA adduct formation and mutations.</p>Fórmula:C3H5NO2Forma y color:SolidPeso molecular:87.08Acremin F
CAS:<p>Acremin F is a useful organic compound for research related to life sciences. The catalog number is T124074 and the CAS number is 863480-61-9.</p>Fórmula:C12H20O4Forma y color:SolidPeso molecular:228.288Isariin C
CAS:Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.Fórmula:C28H49N5O7Forma y color:SolidPeso molecular:567.72Moth Cytochrome C (MCC) (88-103)
CAS:Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.Fórmula:C79H133N23O25Pureza:98%Forma y color:SolidPeso molecular:1805.04Mefox
CAS:<p>Mefox is a bioactive chemical.</p>Fórmula:C20H23N7O7Forma y color:SolidPeso molecular:473.44AY 9944 dihydrochloride
CAS:<p>AY 9944 dihydrochloride is a intermediate.</p>Fórmula:C22H30Cl4N2Pureza:99.22% - 99.82%Forma y color:SoildPeso molecular:464.3C22 Galactosylceramide (d18:1/22:0)
CAS:<p>C22 Galactosylceramide, a CNS sphingolipid, rises in mouse spinal cord on a methionine-restricted diet, found in Alzheimer's hippocampus.</p>Fórmula:C46H89NO8Forma y color:SolidPeso molecular:784.204-methyl-2-Oxovalerate (sodium salt)
CAS:<p>4-Methyl-2-oxovalerate is an L-leucine precursor/metabolite and a key compound in 2-methylpropyl glucosinolate synthesis and diabetes marker.</p>Fórmula:C6H9NaO3Forma y color:SolidPeso molecular:152.12(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
CAS:<p>(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups.</p>Fórmula:C10H18N2O2S2Forma y color:SolidPeso molecular:262.395-hydroxy Indomethacin
CAS:<p>5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes.</p>Fórmula:C18H14ClNO4Forma y color:SolidPeso molecular:343.76Glycolithocholic acid, sodium salt
CAS:<p>Sodium glycolithocholate is a bile acid salt used to diagnose UC, NASH, and PSC.</p>Fórmula:C26H42NNaO4Pureza:99.95%Forma y color:SolidPeso molecular:455.61Spaglumic acid acetate
Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.Fórmula:C13H20N2O10Pureza:99.49%Forma y color:SolidPeso molecular:364.3124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Fórmula:C27H44O2Peso molecular:400.64Osteocalcin, bovine
Osteocalcin, bovine is a vitamin K-dependent bone-specific protein, also known as bone gamma-carboxyglutamate protein (BGLAP). It is a small (49 amino acids) non-collagenous hormone.Fórmula:C263H372N66O82S2Peso molecular:5830.64094AMK318
AMK318 (Immobilized cephalexin acylase) is a biocatalyst and a critical enzyme in novel biocatalyst technology. Enzyme engineering focuses on improving enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions (such as low or high pH). By incorporating stimulus responsiveness into these enzyme modifications, dynamic control of activity becomes feasible.3-Methylcholanthrene
CAS:3-Methylcholanthrene is a carcinogenic polycyclic hydrocarbon formed during combustion, accumulates in prostate tissue, and serves as a prostate cancer model.Fórmula:C21H16Pureza:99.49%Peso molecular:268.35M145724
CAS:M145724 ((3Z,6E)-1-N-Methylalbonoursin) is a metabolite that can be extracted from Streptomyces albus.Fórmula:C16H18N2O2Peso molecular:270.33Aspartate Aminotransferase, Human
Aspartate Aminotransferase, Human is a biocatalyst and serves as a pivotal enzyme in new biotechnology. Enzyme engineering aims to improve the reaction kinetics, substrate specificity, and activity under extreme conditions (such as low or high pH). By introducing stimuli-responsive modifications to these enzymes, the dynamic regulation of activity can also be achieved.Creatine Kinase (CPK/CK), Bovine Heart
Creatine Kinase (CPK/CK), Bovine Heart (CK, CPK, Creatine Phosphokinase), is a biological material or organic compound suitable for use in life sciences research.ASP8477
CAS:ASP8477 is a potent and selective FAAH inhibitor. It increases anandamide levels in the brain when administered orally. In rat models of neuropathic and osteoarthritic pain, ASP8477 demonstrates significant efficacy without causing motor coordination issues. A single oral dose of ASP8477 improves thermal hyperalgesia and cold allodynia in rats with chronic constriction nerve injury. Moreover, ASP8477 restores the decreased muscle pressure threshold in a myalgia model induced by reserpine. Research indicates that ASP8477 possesses analgesic effects effective for alleviating neuropathic and functional pain, making its pharmacological properties suitable for chronic pain treatment.Fórmula:C18H19N3O3Peso molecular:325.36(Z)-7-Dodecen-1-ol
CAS:(Z)-7-Dodecen-1-ol counteracts the attractive properties of Z-7-dodecen-1-yl acetate.Fórmula:C12H24OPeso molecular:184.32RSRGVFF
<p>RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 μM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of ACE. RSRGVFF can be further explored for hypertension research.</p>Fórmula:C40H61N13O9Forma y color:SolidPeso molecular:867.994UK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Fórmula:C72H105N19O25S3Forma y color:SolidPeso molecular:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Forma y color:SolidPeso molecular:1904.11(2R,3R)-2,3,4-Trihydroxybutanoic acid
CAS:(2R,3R)-2,3,4-Trihydroxybutanoic acid, also known as erythorbic acid, is a naturally occurring organic acid found in various bodily fluids including aqueous humor, urine, plasma, cerebrospinal fluid, and synovial fluid. It is prevalent in both healthy adults and children and is produced through the oxidation of GlcNAc.Fórmula:C4H8O5Forma y color:SolidPeso molecular:136.1iso-C15:0 3-OH
CAS:Iso-C15:0 3-OH is a fatty acid that can be isolated from the PLRT strain. PLRT is a rod-shaped, Gram-negative, chemolithoheterotrophic, obligately aerobic bacterium, obtained from the feces of the mollusk Aplysia punctata.Fórmula:C15H30O3Forma y color:SolidPeso molecular:258.397Glucoiberin potassium
CAS:Glucoiberin potassium is an active compound.Fórmula:C11H21KNO10S3Forma y color:SolidPeso molecular:462.58Epothilone C
CAS:<p>Epothilone C is a polyketide natural product. It is produced through the collaborative action of a nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) molecules within a multi-enzyme system. Epothilone C is utilized in tumor research.</p>Fórmula:C26H39NO5SForma y color:SolidPeso molecular:477.65720-hydroxy Prostaglandin E2
CAS:20-hydroxy PGE2 is a cytochrome P450 metabolite of PGE2, formed via ω-oxidation and β-oxidation.Fórmula:C20H32O6Forma y color:SolidPeso molecular:368.46308-R-C4-PEG3-C1-Boc
CAS:308-R-C4-PEG3-C1-Boc is an SGK3 ligand-linker conjugate, utilized in the synthesis of PROTAC SGK3 degrader-2.Fórmula:C39H53FN6O9SForma y color:SolidPeso molecular:800.943-Aminobenzoic acid
CAS:Compound PDK0420, with CAS No. 99-05-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0420 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C7H7NO2Forma y color:SolidPeso molecular:137.13α-Amylase/α-Glucosidase-IN-17
<p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>Fórmula:C19H18FNOForma y color:SolidPeso molecular:295.35RORγ agonist 2
RORγ agonist2 (Compound 34) is a selective RORγ agonist with an EC50 of 0.03 μM for hRORγ. It significantly inhibits tumor growth in an MC38 tumor mouse model with the same genetic background.Forma y color:Odour SolidDeacetylsclerotiorin, (-)-
CAS:deacetylsclerotiorin is a new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.Fórmula:C19H21ClO4Forma y color:SolidPeso molecular:348.82PPL-100
CAS:PPL-100, a HIV protease inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C33H45N4O9PSPureza:98%Forma y color:SolidPeso molecular:704.77DSPE-PEG3400-CSTSMLKAC
DSPE-PEG3400-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. CSTSMLKAC is capable of mediating phage selective homing to ischemic cardiac tissue. DSPE-PEG3400-CSTSMLKAC can be utilized for drug delivery.Forma y color:Odour SolidPROTAC sEH degrader-2
PROTACsEH degrader-2 is a PROTAC degrader that targets soluble epoxide hydrolase (sEH), with pIC50 values of 8.37 (human sEH-H) and 7.12 (mouse sEH-H). It is applicable for research into inflammation and neuroinflammation-related diseases, such as Alzheimer's disease.Forma y color:Odour SolidCK1δ/CK1ε liagnd-1
<p>CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.</p>Fórmula:C21H20F2N6Forma y color:SolidPeso molecular:394.42VH-N412
CAS:VH-N412 is a carrier-modified neurotrophin (NT) known for its excellent ability to penetrate the blood-brain barrier. This compound actively binds to both low-density lipoprotein receptor (LDLR) and neurotropin receptor 1 (NTSR-1), acting as an inducer of pharmacologically induced hypothermia (PIH). Additionally, VH-N412 exhibits anticonvulsant and neuroprotective properties, making it a valuable agent for research in neurological disorders such as epilepsy.Fórmula:C94H163N27O24S3Forma y color:SolidPeso molecular:2151.66Petromyzonol
CAS:Petromyzonol: A sea lamprey bile product; key to spawning as a pheromone, detectable at low levels.Fórmula:C24H42O4Forma y color:SolidPeso molecular:394.59Corynecin V
CAS:Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.Fórmula:C14H18N2O6Forma y color:SolidPeso molecular:310.3S-4048
CAS:S-4048 is a potent inhibitor of glucose-6-phosphate translocase (G6P T1).Fórmula:C32H30ClN3O7Forma y color:SolidPeso molecular:604.05Alytesin
CAS:Amphibian bombesin-like peptideFórmula:C68H106N22O17SPureza:98%Forma y color:SolidPeso molecular:1535.77
