Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(270 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(125 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8625 productos de "Metabolismo"
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m-PEG8-DSPE
<p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>Fórmula:C59H116NO17PPureza:98%Forma y color:SolidPeso molecular:1142.52IDO1-IN-12
CAS:<p>IDO1-IN-12 is a potent and orally available IDO1 inhibitor.</p>Fórmula:C21H19F3N2O2Forma y color:SolidPeso molecular:388.39cis-Vitamin K1
CAS:<p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>Fórmula:C31H46O2Forma y color:SolidPeso molecular:450.70Vitamin K1 2,3-epoxide
CAS:<p>Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle.</p>Fórmula:C31H46O3Pureza:98% - 98.05%Forma y color:SolidPeso molecular:466.72,5-Anhydro-D-glucitol-1,6-diphosphate
CAS:<p>2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.</p>Fórmula:C6H14O11P2Forma y color:SolidPeso molecular:324.12THX6
<p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>Fórmula:C22H18Cl2N4O2Forma y color:SolidPeso molecular:441.31Hydroxycotinine
CAS:<p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>Fórmula:C10H12N2O2Pureza:98%Forma y color:SolidPeso molecular:192.218NU227326
CAS:<p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>Fórmula:C53H61FN8O7Forma y color:SolidPeso molecular:941.099Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS:<p>Preterramide C is a fungal metabolite that has been found inA.</p>Fórmula:C24H23N3O7Forma y color:SolidPeso molecular:465.46(S)-3,4-Dihydroxybutyric acid
CAS:<p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>Fórmula:C4H8O4Pureza:98%Forma y color:SolidPeso molecular:120.12-Hydroxyquinoline
CAS:<p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7NOForma y color:White SolidPeso molecular:145.15L-Lactate dehydrogenase
CAS:<p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>Forma y color:SolidH-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.Fórmula:C18H31N3O6Pureza:97.15%Forma y color:SolidPeso molecular:385.46FXIIa-IN-1 HCl
CAS:<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Fórmula:C21H17ClN2O6Pureza:99.61%Forma y color:SoildPeso molecular:428.823-Oxo-7-hydroxychol-4-enoic acid
CAS:<p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>Fórmula:C24H36O4Forma y color:SolidPeso molecular:388.541α, 25-Dihydroxy VD2-D6
CAS:<p>1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.</p>Fórmula:C28H44O3Pureza:98%Forma y color:SolidPeso molecular:434.68ZINC77292789
CAS:<p>ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which</p>Fórmula:C33H38N2O13Pureza:99.24%Forma y color:SolidPeso molecular:670.66DSPE-PEG2000-PP1
<p>DSPE-PEG2000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide specifically targets inflammatory atherosclerotic plaques. DSPE-PEG2000-PP1 is utilized in drug delivery applications.</p>Forma y color:Odour SolidDSPE-PEG1000-LTLRWVGLMS
<p>DSPE-PEG1000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). The receptor for LLRWVGLMS is the chondroitin sulfate proteoglycan NG2. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG1000-LTLRWVGLMS can be utilized for drug delivery.</p>Forma y color:Odour SolidDSPE-PEG2000-NGR
<p>DSPE-PEG2000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide specifically targets the tumor vasculature antigen CD13. This compound is suitable for drug delivery applications.</p>Forma y color:Odour SolidDSPE-PEG1000-YIGSR
<p>DSPE-PEG1000-YIGSR is a PEG compound consisting of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP) to enhance adhesion and spreading of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG1000-YIGSR is applicable for drug delivery.</p>Forma y color:Odour SolidDSPE-PEG1000-T7
<p>DSPE-PEG1000-T7 is a PEG compound composed of DSPE and transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR. DSPE-PEG1000-T7 is applicable in drug delivery.</p>Forma y color:Odour SolidDSPE-PEG2000-ANG
<p>DSPE-PEG2000-ANG is a PEG compound composed of DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficiency to LRP1 and has been used for targeted delivery to gliomas. DSPE-PEG2000-ANG can be utilized in drug delivery applications.</p>Forma y color:Odour SolidSinbaglustat
CAS:<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Fórmula:C11H23NO4Pureza:99.93%Forma y color:SolidPeso molecular:233.3DSPE-PEG5000-M2pep
<p>DSPE-PEG5000-M2pep is a PEG compound composed of DSPE and the M2 macrophage-targeting peptide (M2pep). Serving either as a monovalent or multivalent ligand, M2pep is conjugated with pro-apoptotic peptides to direct toxicity specifically toward M2 macrophages. DSPE-PEG5000-M2pep is applicable for drug delivery.</p>Forma y color:Odour SolidIrsogladine maleate
CAS:<p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7Cl2N5Forma y color:SolidPeso molecular:256.09Adefovir diphosphate 2TEA
<p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>Fórmula:C20H43N7O7P2Pureza:98.33%Forma y color:SolidPeso molecular:555.55DSPE-PEG5000-ANG
<p>DSPE-PEG5000-ANG is a PEGylated compound formed by DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficacy to LRP1 and has been utilized for targeting glioma delivery. DSPE-PEG5000-ANG is applicable in drug delivery.</p>Forma y color:Odour SolidDSPE-PEG5000-T7
<p>DSPE-PEG5000-T7 is a PEG-based compound composed of DSPE and transferrin receptor peptide (T7). T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG5000-T7 is applicable in drug delivery.</p>Forma y color:Odour SolidDSPE-PEG5000-TH
<p>DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.</p>Forma y color:Odour SolidDSPE-PEG1000-EB1
<p>DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.</p>Forma y color:Odour SolidDSPE-PEG3000-TAT
<p>DSPE-PEG3000-TAT is a PEG compound composed of DSPE and a cell-penetrating peptide (TAT). It is used for drug delivery.</p>Forma y color:Odour SolidZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Fórmula:C23H24FNO4Pureza:99.68% - >99.99%Forma y color:SolidPeso molecular:397.44GGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H26Cl2N6O5Forma y color:SolidPeso molecular:428.13417CP-LC-1422
<p>CP-LC-1422 is a homocysteine-derived ionizable amino lipid known for its efficient RNA delivery capabilities, enabling high-level protein expression in vivo. When formulated in lipid nanoparticles (LNP) and administered intravenously, it demonstrates significant spleen-targeting properties without observed notable toxicity.</p>Fórmula:C51H97N3O8S3Forma y color:SolidPeso molecular:975.64378DSPE-PEG2000-T7
<p>DSPE-PEG2000-T7 is a PEG compound composed of DSPE and the transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR, making DSPE-PEG2000-T7 useful for drug delivery applications.</p>Forma y color:Odour SolidPorcine Factor Xa
CAS:<p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>Forma y color:SolidCP-610431
CAS:<p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>Fórmula:C30H37N3O2Forma y color:SolidPeso molecular:471.645C12 DG PEG (MW 2000)
<p>C12 DG PEG (1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol) (MW 2000) is a polyethylene glycol lipid that can be utilized in the formation of lipid nanoparticles and liposomes. C12 DG PEG (MW 2000) shows potential for use in cancer research.</p>Forma y color:Odour SolidAminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Fórmula:C12H16F2N2O4SForma y color:SolidPeso molecular:322.07988DSPE-PEG2000-ESBP
<p>DSPE-PEG2000-ESBP is a PEGylated compound composed of DSPE and E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Forma y color:Odour SolidPhosphodiesterase
CAS:<p>PDE enzyme hydrolyzes cyclic nucleotides, regulates signal transduction, and varies in type (PDE1-PDE11) with disease research potential.</p>Forma y color:Solid1'-Hydroxy bufuralol
CAS:<p>1'-Hydroxy bufuralol is a metabolite of bufuralol, an orally active β-adrenoceptor blocker used in the study of hypertension and cardiac arrhythmias.</p>Fórmula:C16H23NO3Forma y color:SolidPeso molecular:277.369(S)-HOTrE
CAS:<p>9(S)-HOTrE is a plant metabolite and octadecatrienoic acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid.</p>Fórmula:C18H30O3Forma y color:SolidPeso molecular:294.43SCD1 inhibitor-3
CAS:<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Fórmula:C19H16FN7O2Pureza:99.5%Forma y color:SolidPeso molecular:393.37Equilenin
CAS:<p>Equilenin (E 400) is a natural estrogen that is an endocrine disruptor and has been used in breast cancer research.</p>Fórmula:C18H18O2Pureza:99.4%Forma y color:SolidPeso molecular:266.33Seco Rapamycin sodium salt
CAS:<p>Seco Rapamycin sodium salt is a ring-opened product of Rapamycin.</p>Fórmula:C51H79NNaO13Pureza:98%Forma y color:SolidPeso molecular:937.177DSPE-PEG5000-SP94
<p>DSPE-PEG5000-SP94 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (SP94). SP94 demonstrates specific binding affinity to hepatocellular carcinoma (HCC) cells.</p>Forma y color:Odour SolidDSPE-PEG5000-F3
<p>DSPE-PEG5000-F3 consists of DSPE and the nucleolin-targeting peptide (F3) and is a PEGylated compound. The F3 peptide specifically binds to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG5000-F3 is applicable for drug delivery.</p>Forma y color:Odour SolidImperatoxin A TFA
<p>Imperatoxin A TFA, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, acts as an activator of Ca2+-release channels/ryanodine receptors (RyRs). It facilitates the influx of Ca2+ from the sarcoplasmic reticulum into the cell.</p>Fórmula:C148H254N58O45S6·xC2HF3O2Forma y color:SolidPeso molecular:3758.35 (free base)
