Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(74 productos)
- CETP(20 productos)
- Anhídrido carbónico(185 productos)
- Caseína quinasa(137 productos)
- DHFR(34 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(289 productos)
- FAAH(65 productos)
- FXR(59 productos)
- Factor Xa(83 productos)
- Ácido graso sintasa(36 productos)
- Ferroptosis(218 productos)
- GR(3 productos)
- GSNOR(4 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(145 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(34 productos)
- IDO(84 productos)
- LDL(8 productos)
- Lipasa(104 productos)
- Lípido(62 productos)
- Lipoxigenasa(132 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(38 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(168 productos)
- Fosfolipasa(82 productos)
- ROR(43 productos)
- Receptor de retinoides(28 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(43 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9054 productos de "Metabolismo"
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LYP-IN-3
<p>LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway</p>Fórmula:C35H27NO6SPureza:98%Forma y color:SolidPeso molecular:589.66ω-Conotoxin CVIF
<p>ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, demonstrating an IC50 value of 34.3 nM in isolated rat DRG neurons.</p>Fórmula:C101H170N40O33S6Pureza:98%Forma y color:SolidPeso molecular:2665.07L-Isoleucyl-L-arginine
CAS:<p>L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in</p>Fórmula:C12H25N5O3Pureza:98%Forma y color:SolidPeso molecular:287.36PTPσ Inhibitor, ISP
PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling.Fórmula:C177H306N66O54S3Pureza:98%Forma y color:SolidPeso molecular:4318.93Erythronic acid potassium
<p>Potassium erythronate is an intrinsic carbohydrate metabolite utilized in researching metabolic diseases.</p>Fórmula:C4H7KO5Pureza:98%Forma y color:SolidPeso molecular:173.99305Imperatoxin A
CAS:Imperatoxin A, a peptide toxin sourced from the African scorpion Pandinus imperator, functions as an activator of Ca2+-release channels/ryanodine receptors (Fórmula:C148H254N58O45S6Pureza:98%Forma y color:SolidPeso molecular:3758.35Mortatarin F
<p>Mortatarin F (Compound 1), a renyleted flavonoid derived from mulberry leaves, functions as an α-glucosidase inhibitor with an IC50 value of 8.7 μM, making it</p>Fórmula:C25H30O7Pureza:98%Forma y color:SolidPeso molecular:442.5Ovalbumin (154-159)
CAS:<p>Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in</p>Fórmula:C28H52N10O9Pureza:98%Forma y color:SolidPeso molecular:672.77CA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Fórmula:C7H9N7O3S3Pureza:98%Forma y color:SolidPeso molecular:335.39Denecimig
CAS:<p>Denecimig (Mim8) is a bispecific and humanized IgG4κ antibody, hemophilia A, activated coagulation factors IXa (FIXa) and X (FX) arresting bleeding.</p>Pureza:95%Forma y color:LiquidCarbonic anhydrase inhibitor 15
<p>Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].</p>Fórmula:C27H33N5O2S2Pureza:98%Forma y color:SolidPeso molecular:523.71IHMT-IDH1-053
IHMT-IDH1-053 (compound 16) is an irreversible inhibitor exhibiting high selectivity for the IDH1 R132H mutant, achieving an IC50 of 4.7 nM.Fórmula:C25H33FN6O4SPureza:98%Forma y color:SolidPeso molecular:532.63Ledelabricin alfa
<p>Ledelabricin alfa, an isoform A variant of human proteoglycan 4 (PRG4), functions as a lubricant for joints and boundaries.</p>Pureza:98%Forma y color:Odour Liquidω-Conotoxin FVIA
ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerveFórmula:C98H164N36O33S6Pureza:98%Forma y color:SolidPeso molecular:2566.96Cryptosporioptide A
CAS:Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides.Fórmula:C18H17NO10Pureza:98%Forma y color:SolidPeso molecular:407.33ITH12711
ITH12711, a PP2A ligand, can traverse the blood-brain barrier (BBB) and exerts neuroprotection by restoring PP2A-phosphatase activity [1].Fórmula:C12H20O5Pureza:98%Forma y color:SolidPeso molecular:244.28Stevisalioside A
Stevisalioside A (Compound 2), isolated from the roots of Stevia serrata, is an orally active antidiabetic agent that inhibits Protein Tyrosine Phosphatase 1B (Fórmula:C35H50O15Pureza:98%Forma y color:SolidPeso molecular:710.76PF-07247685
<p>PF-07247685, a potent BCKDC kinase (BDK) inhibitor (EC 50 = 2.2 nM), enhances the binding between BDK and the BCKDH E2 core subunit to block E1 phosphorylation.</p>Fórmula:C21H20N2O3SPureza:98%Forma y color:SolidPeso molecular:380.46Maurocalcine
CAS:<p>Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3.</p>Fórmula:C156H270N56O46S6Pureza:98%Forma y color:SolidPeso molecular:3858.55NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.Fórmula:C56H74N8O7SPureza:98%Forma y color:SolidPeso molecular:1003.3A3373
CAS:<p>A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of</p>Fórmula:C17H9F7N2OPureza:98%Forma y color:SoildPeso molecular:390.26α-Glucosidase-IN-31
<p>α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and</p>Fórmula:C18H18N4Pureza:98%Forma y color:SolidPeso molecular:290.36RORγt inverse agonist 31
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (Fórmula:C23H15Cl2F3N4O3SPureza:98%Forma y color:SolidPeso molecular:555.36Eurestobart
CAS:<p>Eurestobart is a humanized IgG1κ (IgG1 kappa) monoclonal antibody that specifically targets the enzyme ectonucleoside triphosphate diphosphohydrolase (ENTPDase</p>Pureza:98%Forma y color:Liquidα-Glucosidase-IN-38
α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor, demonstrating an IC50 of 12.44±0.38 μM, and is significant in the context of DiabetesPureza:98%Forma y color:Odour SolidAlternaphenol B2
<p>Alternaphenol B2, a selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1m), is sourced from the coral-derived fungus Parengyodontium album SCSIO</p>Pureza:98%Forma y color:Odour SolidVHL-IN-1
<p>VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1α and</p>Fórmula:C28H37FN4O4SPureza:98%Forma y color:SolidPeso molecular:544.68Myoregulin TFA
Myoregulin (MLN peptide) TFA, belonging to the regulin family, is a regulator of muscle performance through modulation of intracellular calcium dynamics.Fórmula:C239H391N53O67S3·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:5175.17 (free base)α-Glucosidase-IN-36
α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65Fórmula:C26H24BrN5O3SPureza:98%Forma y color:SolidPeso molecular:566.47Ovotransferrin (328-332)
CAS:<p>Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and</p>Fórmula:C25H46N8O7Pureza:98%Forma y color:SolidPeso molecular:570.68MAGL-IN-9
<p>MAGL-IN-9, also referred to as compound 16, is a reversible inhibitor of monoacylglycerol lipase (MAGL) with a potent IC50 value of 2.7 nM [1].</p>Pureza:98%Forma y color:Odour Solidα-Glucosidase-IN-40
<p>α-Glucosidase-IN-40 (compound 5) serves as a noncompetitive inhibitor of the α-glucosidase enzyme, exhibiting an inhibitory concentration (IC50) of 24.62 μM [1</p>Pureza:98%Forma y color:Odour SolidAntioxidant agent-13
<p>Compound 5f (Antioxidant agent-13) is an antioxidant that demonstrates inhibition of DPPH and FRAP with half maximal inhibitory concentrations (IC50s) of 80.33</p>Fórmula:C12H8N4O7Pureza:98%Forma y color:SolidPeso molecular:320.21Hepcidin-25 (human) (acetate)
CAS:<p>Hepcidin-25 (human) acetate is a modulator of iron metabolism that demonstrates anti-inflammatory and antibacterial effects through the modulation of iron-</p>Fórmula:C113H170N34O31S9·xC2H4O2Pureza:98%Forma y color:Solidω-Conotoxin MVIID
<p>ω-Conotoxin MVIID (SNX-238) is a peptide from the Conus genus that inhibits the ω-Conotoxin-GVIA-sensitive, high-threshold calcium (Ca 2+) current in fish</p>Fórmula:C99H164N42O33S7Pureza:98%Forma y color:SolidPeso molecular:2695.08ω-Conotoxin CVIA
CAS:<p>ω-Conotoxin CVIA, a 27-amino acid neuropeptide, functions as a blocker of voltage-sensitive calcium channels (VSCCs) [1].</p>Fórmula:C97H161N39O36S6Pureza:98%Forma y color:SolidPeso molecular:2641.95Casuarictin
CAS:<p>Casuarictin, a potent competitive inhibitor of α-glucosidase, exhibits an IC50 of 0.21 μg/mL and functions as a presenilin stabilization factor-like (PSFL)</p>Fórmula:C41H28O26Pureza:98%Forma y color:SolidPeso molecular:936.65Flaccidoside III
CAS:<p>Flaccidoside III, a flavonoid and triterpenoid compound extracted from the aerial parts of N.</p>Fórmula:C59H96O26Pureza:98%Forma y color:SolidPeso molecular:1221.38hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFórmula:C17H14N6O3SPureza:98%Forma y color:SolidPeso molecular:382.4HIF-1α-IN-2 hydrochloride
<p>HIF-1α-IN-2 hydrochloride is a potent HIF-1α inhibitor exhibiting anticancer activity, demonstrated by IC50 values of 28 nM in MDA-MB-231 cells and 15 nM in</p>Fórmula:C21H20ClN3OSPureza:98%Forma y color:SolidPeso molecular:397.92Forrestiacids K
CAS:<p>Forrestiacid K, a terpenoid derived from Pseudotsuga forrestii, functions as an inhibitor of ATP-citrate lyase (ACL) [1].</p>Fórmula:C50H74O6Pureza:98%Forma y color:SolidPeso molecular:771.12Forrestiacids J
CAS:<p>Forrestiacid J is an inhibitor of ATP-citrate lyase (ACL), exhibiting an IC50 value of 2.6 μM [1].</p>Fórmula:C50H74O6Pureza:98%Forma y color:SolidPeso molecular:771.12Stevisaliosides D
<p>Stevisaliosides D (Compound 5), extracted from the roots of Stevia serrata, exhibits inhibition of PTP1B with an IC50 of 31.8 μM and has applications in</p>Fórmula:C35H54O16Pureza:98%Forma y color:SolidPeso molecular:730.79Glucocerebrosidase
CAS:<p>Glucocerebrosidase (Glucosylceramidase; GBA), a lysosomal enzyme, catalyzes the hydrolysis of the β-glucosidic linkage in glucocerebroside (GC) to yield glucose</p>Pureza:98%Forma y color:SolidPF-07238025
<p>PF-07238025, a potent branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with an EC50 of 19 nM, enhances the stability of the BDK-BCKDH core E2</p>Fórmula:C19H18N2O3SPureza:98%Forma y color:SolidPeso molecular:354.42Alanine aminotransferase
CAS:<p>Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-</p>Pureza:98%Forma y color:SolidCalciseptin
CAS:<p>Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p.</p>Fórmula:C299H468N90O87S10Pureza:98%Forma y color:SolidPeso molecular:7036.12HIF-1α-IN-6
<p>HIF-1α-IN-6 (compound 3s) is a potent inhibitor of HIF-1α, demonstrating IC50 values of 0.6 nM and 53.3 nM in MiaPaCa-2 and MDA-MB-231 cells, respectively.</p>Pureza:98%Forma y color:Odour SolidIDO1-IN-23
<p>IDO1-IN-23 (compound 41) is a potent inhibitor of human indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 13 μM [1].</p>Pureza:98%Forma y color:Odour SolidAmidase
CAS:<p>Amidases, belonging to the nitrilase superfamily, catalyze amide hydrolysis to yield carboxylic acid and ammonia.</p>Pureza:98%Forma y color:Solid
